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Surgical apgar score predicts early complication in transfemoral amputees:Retrospective study of 170 major amputations

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World Journal of Orthopedics 2016年第12期7卷 832-838页

作者： Christian Wied Nicolai B Foss Morten t Kristensen Gitte Holm thomas Kallemose Anders troelsen Department of Orthopedic Surgery Copenhagen University Hospital Hvidovre Department of Anesthesiology and Intensive Care Copenhagen University Hospital Hvidovre Physical Medicine and Rehabilitation Research-Copenhagen Department of Physical TherapyCopenhagen University Hospital Hvidovre Clinical Research Centre Copenhagen University Hospital Hvidovre

AIM to assess whether the surgical apgar score(SAS) is a prognostic tool capable of identifying patients at risk of major complications following lower extremity amputations *** this was a single-center,retrospective observational cohort study conducted between January 2013 and April 2015. All patients who had either a primary transtibial amputation(ttA) or transfemoral amputation(tFA) conducted at our institution during the study period were assessed for inclusion. All ttA patients underwent a standardized one-stage operative procedure(ad modum Persson amputation) performed approximately 10 cm below the knee joint. All ttA procedures were performedwith sagittal flaps. tFA procedures were performed in one stage with amputation approximately 10 cm above the knee joint,performed with anterior/posterior flaps. trained residents or senior consultants performed the surgical procedures. the SAS is based on intraoperative heart rate,blood pressure and blood loss. Intraoperative parameters of interest were collected by revising electronic health records. the first author of this study calculated the SAS. Data regarding major complications were not revealed to the author until after the calculation of SAS. the SAS results were arranged into four groups(SAS 0-4,SAS 5-6,SAS 7-8 and SAS 9-10). the cohort was then divided into two groups representing low-risk(SAS ≥ 7) and highrisk patients(SAS tablished threshold. the outcome of interest was the occurrence of major complications and death within 30-d of *** A logistic regression model with SAS 9-10 as a reference showed a significant linear association between lower SAS and more postoperative complications [all patients: OR = 2.00(1.33-3.03),P = 0.001]. this effect was pronounced for tFA [OR = 2.61(1.52-4.47),P t increase was observed for the high-risk group compared to the low-risk group for all patients [OR = 2.80(1.40-5.61),P = 0.004] and for the tFA sub-

关键词： Surgical apgar score Mortality transfemoral amputation Post-operative complication Lower extremity amputation

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Proteomics of protein post-translational modifications implicated in neurodegeneration

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translational Neurodegeneration 2014年第1期3卷 156-168页

作者： Ru-Jing Ren Eric B Dammer Gang Wang Nicholas t Seyfried Allan I Levey Department of Neurology Center for Neurodegenerative DiseasesEmory University School of MedicineAtlantaGA 30322USA Department of Biochemistry Center for Neurodegenerative DiseasesEmory University School of MedicineAtlantaGA 30322USA Department of Pharmacology Center for Neurodegenerative DiseasesEmory University School of MedicineAtlantaGA 30322USA Emory Proteomics Service Center Center for Neurodegenerative DiseasesEmory University School of MedicineAtlantaGA 30322USA

Mass spectrometry(MS)-based proteomics has developed into a battery of approaches that is exceedingly adept at identifying with high mass accuracy and precision any of the following:oxidative damage to proteins(redox proteomics),phosphorylation(phosphoproteomics),ubiquitination(diglycine remnant proteomics),protein fragmentation(degradomics),and other posttranslational modifications(PtMs).Many studies have linked these PtMs to pathogenic mechanisms of *** date,identifying PtMs on specific pathology-associated proteins has proven to be a valuable step in the evaluation of functional alteration of proteins and also elucidates biochemical and structural explanations for possible pathophysiological mechanisms of neurodegenerative *** review provides an overview of methods applicable to the identification and quantification of PtMs on proteins and enumerates historic,recent,and potential future research endeavours in the field of proteomics furthering the understanding of PtM roles in the pathogenesis of neurodegeneration.

关键词： Proteomics Protein posttranslational modifications Neurodegeneration Alzheimer’s disease Parkinson’s disease

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Dielectric properties of amorphous Zr-Al-O and Zr-Si-O thin films

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Journal of Advanced Dielectrics 2015年第1期5卷 71-78页

作者： t.A.Naoi Hanjong Paik M.L.Green R.B.van Dover Department of Materials Science and Engineering Cornell University IthacaNew York 14853USA National Institute of Standards and technology Gaithersburg Maryland 20899USA

We have systematically studied the composition dependence of the dielectric properties of Zr_(1-x)Al_(x)O_(2-x/2)and Zr_(1-x)Si_(x)O_(2).An essentially linear variation of the static dielectric constant,ε_(s),was observed as a function of composition,x,for compositions rich in the p-block element,i.e.,x>0.4,for both chemical *** an abrupt change inε_(s)is found near x≈0.35,associated with the onset of crystallinity in as-deposited *** fields do not show a comparable composition *** of the index of refraction at optical frequencies,combined with a simple Clausius-Mossotti interpretation,indicates that low-frequency(ionic)contributions to the polarizability exhibit systematic deviation with respect to values linearly interpolated from the *** trends are not consistently affected by the presence of crystalline order,but are related to changes associated with heterogeneous local oxygen coordination and bonding.

关键词： Permitivitty amorphous zirconia

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Using a systems modeling approach to improve soil management and soil quality

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Frontiers of Agricultural Science and Engineering 2020年第3期7卷 289-295页

作者： Enli WANG Di HE Zhigan ZHAO Chris J.SMItH Ben C.t.MACDONALD CSIRO Agriculture and Food CanberraACT 2601Australia

Soils provide the structural support, water andnutrients for plants in nature and are considered to be thefoundation of agriculture production. Improving soilquality and soil health has been advocated as the goal ofsoil management toward sustainable agricultural intensifi-cation. there have been renewed efforts to define andquantify soil quality and soil health but establishing aconsensus on the key indicators remains difficult. It isargued that such difficulties are due to the former ways ofthinking in soil management which largely focus on soilproperties alone. A systems approach that treats soils as akey component of agricultural production systems ispromoted. It is argued that soil quality must be quantifiedin terms of crop productivity and impacts on ecosystemsservices that are also strongly driven by climate andmanagement interventions. A systems modeling approachcaptures the interactions among climate, soil, crops andmanagement, and their impacts on system performance,thus helping to quantify the value and quality of ***, three examples are presented to demonstrate this. Inthis systems context, soil management must be an integralpart of systems management practices that also includemanaging the crops and cropping systems under specificclimatic conditions, with cognizance of future climatechange.

关键词： APSIM available water capacity nitrogen management soil functional properties soil health soil-plant modeling

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低温金属环境中^198Au半衰期的测量

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原子能科学技术 2009年第6期43卷 481-484页

作者：曾晟 t. Spillane F. Raiola C. Rolls 中国原子能科学研究院核物理研究所北京102413 鲁尔大学鲁尔44780

利用德国鲁尔大学DtL实验室的中子源,通过197Au(n,γ)198Au反应得到198Au@Au样品,在室温(t=293 K)和低温(t=12 K)条件下交替测量金属Au环境中198Au的412 keV特征γ射线,通过分析得到不同温度下198Au的半衰期。实验结果表明,与文献值t1/2... 详细信息

利用德国鲁尔大学DtL实验室的中子源,通过197Au(n,γ)198Au反应得到198Au@Au样品,在室温(t=293 K)和低温(t=12 K)条件下交替测量金属Au环境中198Au的412 keV特征γ射线,通过分析得到不同温度下198Au的半衰期。实验结果表明,与文献值t1/2=(2.694 3±0.000 8)d相比,t=293 K时198Au的半衰期变长(0.4±0.7)%;t=12 K时变长(4.0±0.7)%。这一变化趋向与德拜等离子体模型的预言相符,但其幅度显著小于模型的估计值。

关键词： β-衰变半衰期金属环境温度效应德拜等离子体模型

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A Novel Deep Neural Network for Intracranial Haemorrhage Detection and Classification

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Computers, Materials & Continua 2021年第9期68卷 2877-2893页

作者： D.Venugopal t.Jayasankar Mohamed Yacin Sikkandar Mohamed Ibrahim Waly Irina V.Pustokhina Denis A.Pustokhin K.Shankar Department of ECE KPR Institute of Engineering and TechnologyCoimbatore641407India Department of Electronics and Communication Engineering University College of EngineeringBIT CampusAnna UniversityTiruchirappalli620024India Department of Medical Equipment technology College of Applied Medical SciencesMajmaah UniversityAl Majmaah11952Saudi Arabia Department of Entrepreneurship and Logistics Plekhanov Russian University of EconomicsMoscow117997Russia Department of Logistics State University of ManagementMoscow109542Russia Department of Computer Applications Alagappa UniversityKaraikudi630001India

Data fusion is one of the challenging issues,the healthcare sector is facing in the recent *** diagnosis from digital imagery and treatment are deemed to be the right *** Haemorrhage(ICH),a condition characterized by injury of blood vessels in brain tissues,is one of the important reasons for *** generated by X-rays and Computed tomography(Ct)are widely used for estimating the size and location of *** use manual planimetry,a time-consuming process for segmenting Ct scan *** Learning(DL)is the most preferred method to increase the efficiency of diagnosing *** this paper,the researcher presents a unique multi-modal data fusion-based feature extraction technique with Deep Learning(DL)model,abbreviated as FFE-DL for Intracranial Haemorrhage Detection and Classification,also known as *** proposed FFEDL-ICH model has four stages namely,preprocessing,image segmentation,feature extraction,and *** input image is first preprocessed using the Gaussian Filtering(GF)technique to remove ***,the Density-based Fuzzy C-Means(DFCM)algorithm is used to segment the ***,the Fusion-based Feature Extraction model is implemented with handcrafted feature(Local Binary Patterns)and deep features(Residual Network-152)to extract useful ***,Deep Neural Network(DNN)is implemented as a classification technique to differentiate multiple classes of *** researchers,in the current study,used benchmark Intracranial Haemorrhage dataset and simulated the FFEDL-ICH model to assess its diagnostic *** findings of the study revealed that the proposed FFEDL-ICH model has the ability to outperform existing models as there is a significant improvement in its *** future researches,the researcher recommends the performance improvement of FFEDL-ICH model using learning rate scheduling techniques for DNN.

关键词： Intracerebral hemorrhage fusion model feature extraction deep features classification

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Immersion in the Design: Design-for-assembly of Cable Harnesses

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厦门大学学报（自然科学版） 2002年第S1期41卷 205-206页

作者： J E L Simmons J M Ritchie P O'B Holt G t Russell Manufacturing Systems Research Group Manufacturing Systems Research Group Image Systems Engineering LaboratoryHeriot-Watt UniversityImage Systems Engineering LaboratoryHeriot-Watt University Edinburgh UKEdinburgh UK

Approaches to efficiency in manufacturing and assem bl y over the past 100 years have concentrated frequently on the twin themes of div iding jobs done by people into defined segments and to automating as many of tho se segments as possible. this approach to manufacturing engineering may be char acterised as one of deconstruction and replacement so far as the role of the hum an being is concerned. More recently design engineering has been approached in a similar light with research into ’intelligent’ methods involving, for example, expert systems or genetic algorithms to handle an increasing proportion of desi gn tasks. Expert systems are predicated on the idea that it is possible to capture and systemise significant amounts of professional knowledge: a task that has proved with experience to be much more difficult than when such systems wer e first proposed. Genetic algorithms, notwithstanding considerable research eff ort, have yet to make significant inroads into the practise of design and manufa cture. this paper will draw on new and previous experimental work carried out with supp ort from industry to propose an alternative approach that is enabled by the prod ucts of modern information technology. In this paradigm it is recognised that t he involvement of the human design expert is, for the time being at least, inevi table. Rather than seeking to reduce or even eliminate the " expert" with his or her tacit knowledge, the aim is to provide the expert with interactive to ols including immersive virtual reality so that implicit, human expertise can be applied effectively in the design cycle. the proposed approach is considered in the context of a particularly costly and difficult task, namely the design and planning for manufacture and assembly of c able harnesses for use in electro-mechanical artefacts. the efficient and reli able manufacture of cabling systems for many such products in the aerospace, aut omotive and It sectors provides diverse challenges to des

关键词： Immersion in the Design

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Hybridized Nano-Structure Composed of Metal and Polydiacetylene

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复旦学报（自然科学版） 2005年第5期44卷 821-822页

作者： H. Oikawa A. Masuharat t. Onodera H. Kasai H. Nakanishi Nanomaterials Lab. National Institute for Materials Science Tsukuba 305 - 0044 Japan IMRAM Tohoku University Sendai 980 - 8577 Japan CRESt Japan Science and Technology Agency Tokyo 110-0015 Japan

Polydiacetylene (PDA) is one of the promising candidates for organic third-order nonlinear optical (NLO) material, due to fast optical responsibility and easy processability in comparison with semiconductors etc. the magnitude of NLO property, however, is not still sufficient for the devices applications. Neeves, et al[1] theoretically predicted the enhancement of NLO property for core-shell type hybridized nanocrystal (NC) composed of PDA and metal. In the present study, we have prepared the two kinds of core-shell type hybridized nano-structure, and investigated their optical properties.

关键词：金属纳米结构聚乙烯丁二炔纳米晶体表面胞质基因

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高、低核酸含量原核生物应对资源可利用性降低和原生动物选择性摄食的适应性策略

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中国科学：地球科学 2024年第6期54卷 1901-1913页

作者：胡晨余柳倩陈晓炜刘纪化张瑶 John BAtt 肖喜林石蔷张锐骆庭伟焦念志徐大鹏厦门大学环境与生态学院厦门361102 近海海洋环境科学国家重点实验室厦门大学海洋与地球学院福建省海洋碳汇重点实验室厦门361102 Joint Lab for Ocean Research and Education(LORE)of Dalhousie University Canadaand Shandong University and Xiamen UniversityXiamen 361102China 香港科技大学(广州)地球与海洋大气科学学域广州510000 山东大学海洋研究院青岛266237 Department of Oceanography Dalhousie UniversityHalifaxNova Scotia B3H 4R2Canada 深圳大学高等研究院深圳518060 厦门大学碳中和创新研究中心厦门361102

原核生物在全球海洋生物地球化学循环中发挥重要作用,然而对它们不同生态亚群(即:高核酸(HNA)和低核酸(LNA)含量亚群)的丰度和代谢活性,以及它们的调控因素如何随着海洋环境条件的变化而变化,仍知之甚少.我们在117,000升的大体积培养体... 详细信息

原核生物在全球海洋生物地球化学循环中发挥重要作用,然而对它们不同生态亚群(即:高核酸(HNA)和低核酸(LNA)含量亚群)的丰度和代谢活性,以及它们的调控因素如何随着海洋环境条件的变化而变化,仍知之甚少.我们在117,000升的大体积培养体系中进行了73天的培养实验,深入研究HNA和LNA亚群对资源可利用性降低和原生动物选择性摄食随时间变化的动态响应.研究结果显示,当培养环境资源充足时, HNA亚群的代谢活性高于LNA亚群,但随着资源日益稀缺, HNA亚群代谢下降速度比LNA亚群快,从而使LNA亚群对原核生物活性的贡献稳步增加.与此同时,随着培养体系资源可利用性逐步降低,原生动物的摄食偏好从HNA亚群转向LNA亚群,使得LNA亚群对培养体系的碳流贡献增加.这些结果突显了LNA亚群在资源有限环境中的韧性,阐明了原生动物选择性摄食在资源条件变化时平衡不同亚群中的关键作用,并展示了在不同环境背景下原生动物和原核生物之间复杂的相互适应性.

关键词：微生物环大体积培养实验原核生物自上而下和自下而上调控作用碳流

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Composition of Essential Oils from <i>Litsea acutivena</i>Hayata

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American Journal of Plant Sciences 2019年第4期10卷 615-621页

作者： Do N. Dai Nguyen t. t. Lam Nguyen A. Dung Le t. Huong Dao t. M. Chau Isiaka A. Ogunwande Graduate University of Science and technology Vietnam Academy of Science and Technology Hanoi Vietnam Faculty of Agriculture Forestry and Fishery Nghean College of Economics Vinh Vietnam School of Natural Science Education Vinh University Vinh Vietnam 7 University Drive Aleku Area Osogbo Nigeria

the chemical components of the leaf oil of Litsea acutivena Hayata collected from Pù Huong Natural Reserve, Nghe An Province, Vietnam, were identified by co-chromatography with authentic samples, gas chromatography/mass spectrometry (GC/MS) and linear retention indices. the significant compounds of L. acutivena were α-phellandrene (30.4%) and α-pinene (14.2%). the constituents of essential oil of L. acutivena from Vietnam are being reported for the first time.

关键词： Litsea acutivena Essential Oil terpenes

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