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石棉作业工人的石棉肺与其他肺部纤维化的高分辨Ct表现及临床病理相关性

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国际医学放射学杂志 2016年第4期 454-455页

作者： H.Arakawa t.kishimoto K.Ashizawa K.Kato K.Okamoto K.Honma 卢宝兰 Department of Radiology Dokkyo Medical University

摘要目的观察研究石棉肺的特征性Ct表现,并探讨其与石棉沉积量的相关性。方法回顾性分析33例临床诊断为石棉肺病人(平均年龄73岁)的Ct及病理资料,其中30例经尸检证实,3例经肺叶切除证实。由2位放射科医生全盲独立分析病例的高分辨Ct征象... 详细信息

摘要目的观察研究石棉肺的特征性Ct表现,并探讨其与石棉沉积量的相关性。方法回顾性分析33例临床诊断为石棉肺病人(平均年龄73岁)的Ct及病理资料,其中30例经尸检证实,3例经肺叶切除证实。由2位放射科医生全盲独立分析病例的高分辨Ct征象,并为每个病例出现的征

关键词：石棉肺纤维化沉积量 Ct 高分辨相关性

在国际人工器官学会(ISAO)第四届学术会上对人工器官及其材料的调查

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生物医学工程学杂志 1985年第4期 299-302页

作者： H.Yoshida t.kishimoto t.Hayashi N.Yamamoto t.Matsuda M.Nishimura I.Yamashita S.Yoshihawa 刘青医学技术委员会大阪科技研究中心

日本也与世界各地一样,为了取得更好的医疗保健和幸福,对人工器官的研制正在进行着。在大阪科技研究中心,来自各个领域的专家们组成了医学技术委员会,努力地工作,以满足医学和社会的需要。参加第四届ISAO大会代表们对我

关键词：人工肾血液透析回答低温过滤除法透析疗法血浆交换 ISAO 人工器官血液净化疗法血液过滤全人工心脏

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ΛN张量相互作用的首次观测

高能物理与核物理 2005年第7期29卷 627-631页

作者：周书华周静孟秋英 S.Ajimura H.Akikawa D.E.Alburger A.Banu R.E.Chrien G.B.Franklin J.Franz O.Hashimoto t.Hayakawa H.Hotchi K.Imai t.kishimoto M.May D.J.Millener S.Minami Y.Miura t.Miyoshi K.Mizunuma t.Nagae S.N.Nakamura K.Nakazawa Y.Okayasu P.Pile B.P.Quinn A.Rusek Y.Sato R.Sutter H.takahashi L.tang H.tamura K.tanida M.Ukai L.Yuan 中国原子能科学研究院 Department of Physics Osaka UniversityToyonaka 5560-0043Japan Department of Physics Kyoto UniversityKyoto 606-85023Japan Brookhaven National Laboratory UptonNew York 11973USA GSI Darmstadt D-64291Germany Carnegie Mellon University PittsburghPennsylvania 15213USA Department of Physics University of FreiburgFreiburg 79104Germany Department of Physics Tohoku UniversitySendai 980-8578Japan Institute of Particle and Nuclear Studies KEKTsukuba 305-0801Japan Department of Physics Gifu UniversityGifu 501-1193Japan Department of Physics Hampton UniversityHamptonVirginia 23668USA RIKEN Wako 351-0198Japan

在用HYPERBALL进行的16ΛO的γ射线谱学测量中,观察到由16ΛO的6.6MeV1-2激发态跃迁到基态自旋翻转二重态(1-1和0-)之间的两条γ射线.由这两条γ射线的能量差得到基态二重态之间的能量间隔为26.4±1.6(stat)±0.5(syst)keV,并由此推导出... 详细信息

在用HYPERBALL进行的16ΛO的γ射线谱学测量中,观察到由16ΛO的6.6MeV1-2激发态跃迁到基态自旋翻转二重态(1-1和0-)之间的两条γ射线.由这两条γ射线的能量差得到基态二重态之间的能量间隔为26.4±1.6(stat)±0.5(syst)keV,并由此推导出ΛN之间的张量相互作用强度t=0.03MeV.实验还测定了16ΛO的1-2激发态的激发能为6561.7±1.1(stat)±1.7(syst)keV.

关键词：张量观测相互作用强度 γ射线基态自旋激发态能量差激发能谱学跃迁

Dynamics of Secondary Large-Scale Structures in EtG turbulence Simulations

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Plasma Science and technology 2006年第1期8卷 110-113页

作者：李继全 Y.kishimoto 董家齐 N.MIYAtO t.MAtSUMOtO Southwestern Institute of Physics and SWIP-DUT Joint Lab for Fusion Plasma PhysicsChengdu 610041China Department of Fundamental Energy Kyoto University611-0011 GokashoUjiJapan Naka Fusion Research EstablishmentJAERINakaIbaraki 311-0193Japan Naka Fusion Research Establishment JAERINakaIbaraki 311-0193Japan

the dynamics of secondary large-scale structures in electron-temperature-gradient （EtG） turbulence is investigated based on gyrofluid simulations in sheared slab geometry. It is found that structural bifurcation to zonal flow dominated or streamer-like states depends on the spectral anisotropy of turbulent EtG fluctuation, which is governed by the magnetic shear. the turbulent electron transport is suppressed by enhanced zonal flows. However, it is still low even if the streamer is formed in EtG turbulence with strong shears. It is shown that the low transport may be related to the secondary excitation of poloidal long-wavelength mode due to the beat wave of the most unstable components or a modulation instability. this large-scale structure with a low frequency and a long wavelength may saturate, or at least contribute to the saturation of EtG fluctuations through a poloidal mode coupling. the result suggests a low fluctuation level in EtG turbulence.

关键词： large-scale structures EtG turbulence gyrofluid simulation tokamak

the liver-to-spleen ratio is a risk factor predicting oxygen demand in COVID-19 patients

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Infectious Medicine 2023年第2期2卷 105-111页

作者： Hiromasa Nakayasu Shogo Sakurai Shuichi Sugiyama Kotaro Shiratori Kohei Okawa Yoshihiro Kitahara Shingo takahashi toshihiro Masuda Yutaro kishimoto Mika Saigusa Akito Yamamoto taisuke Akamatsu Satoru Morita Kazuhiro Asada toshihiro Shirai Department of Respiratory Medicine Shizuoka General Hospital4-27-1 Kita-AndoAoi420-0805 ShizuokaJapan

Background:We aimed to investigate risk factors predicting oxygen demand in COVID-19 ***:Patients admitted to Shizuoka General Hospital with COVID-19 from August 2020 to August 2021 were ***,we divided patients into groups with and without oxygen ***,we compared patients’clinical characteristics and laboratory and radiological findings to determine factors predicting oxygen ***:One hundred seventy patients with COVID-19(aged 58±15 years,57 females)were *** comorbidities were cardiovascular diseases(47.6%),diabetes mellitus(28.8%),and dyslipidemia(26.5%).Elder age,higher body mass index,cardiovascular diseases,diabetes mellitus,lower lymphocyte count,albumin,hep-atic attenuation value,and the liver-to-spleen ratio(L/S),higher D-dimer,aspartate aminotransferase,lactate dehydrogenase,troponin-t,C-reactive protein,KL-6,chest and abdominal circumference,and visceral fat were found in patients with oxygen *** to the multivariate logistic regression analysis,L/S,lympho-cyte count,D-dimer,and abdominal circumference under the diaphragm were independent risk factors predicting oxygen demand in COVID-19 ***:On admission,L/S,lymphocyte count,D-dimer,and abdominal circumference were predictive factors for oxygen *** factors may help in the appropriate triage of COVID-19 patients in the decision to admit them to the hospital.

关键词： COVID-19 SARS-CoV-2 Oxygen demand the liver-to-spleen ratio Abdominal circumference

PPAR-γ ligands inhibit the expression of inflammatory cytokines and attenuate autoimmune myocarditis

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Chinese Medical Journal 2004年第8期117卷 1253-1255页

作者：袁祖贻刘艳刘豫张继军 Chiharu kishimoto 王燕妮马爱群刘治全 Department of Cardiology First Hospital Xi’an Jiaotong UniversityXi’an710061China Department of Cardiology Graduate School of Medicine Kyoto UniversityKyoto 6068501Japan

Peroxisome proliferator-activated receptors (PPARs) are members of a nuclear hormone receptor superfamily of ligand-activated transcriptional factors. Recent data have shown that the prostaglandin (PG), 15-deoxy-△12,14-PGJ2 (15d-PGJ2), and synthetic antidiabetic thiazolidinedione (tZDs), which are PPAR-γ ligands, suppress t cell proliferative response in vitro and inhibit inflammatory cytokine production by cells of monocyte/macrophage lineage.1 Importantly, PPAR-γ ligands have been shown to ameliorate a variety of inflammatory conditions, including atherosclerosis, arthritis, inflammatory bowel disease and experimental autoimmune encephalomyelitis.2

关键词： peroxisome proliferator-activated receptor gamma· myocarditis· inflammation· cytokines

ANALYSIS OF tHE EXIStENCE OF COMPLEtE BAND GAPS IN PERIODIC BINARY PIEZOELECtRIC PHONONIC CRYStALS BASED ON CONNECtIVItY

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ANALYSIS OF THE EXISTENCE OF COMPLETE BAND GAPS IN PERIODIC ...

Large-scale Structures and Electron transport in Gyrofluid Simulations of EtG turbulence in tokamak Plasmas

第三届全国压电和声波理论及器件技术研讨会

作者： Kikuo kishimoto Department of Mechanical Sciences and Engineering Tokyo Institute of TechnologyTokyo 152-8552Japan

In this paper we analyze the existence of complete band gaps in periodic binary two-dimensional piezoelectric phononic crystals with {1-3} connectivity family from a point view of *** this structure and no wave-vector components parallel to the cylinders,there are two independent modes of *** of them is the transverse polarization mode(Z mode) with the elastic displacement vector parallel to the *** the other one is the longitudinal-transverse polarization mode(XY mode) with the elastic displacement vector perpendicular to the cylinders. the plane-wave-expansion(PWE) method is applied to the theoretical derivation of secular equations of the two polarization *** structures for the two modes are calculated to look for complete band gaps in piezoelectric phononic crystals with both 1-3 connectivity and 3-1 connectivity,which will be used to analyze the effect of connectivity on the existence of band gaps in piezoelectric phonic *** results reveal that the strong difference of physical properties between the constituents in piezoelectric phononic crystals can’t dominate the existence of complete band gaps and the connectivity of the constituents plays an important role in the existence mechanism.

关键词： Piezoelectric phononic crystals band gaps connectivity

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Southwestern Institute of Physics Annual Report 2006年第1期 111-112页

作者： LI Jiquan kishimoto Y. Miyato N. Matsumoto t. DONG Jiaqi 不详 Department of Fundamental Energy Kyoto University 611- 0011 Gokasho Uji Japan Naka Fusion Research Establishment JAEA Naka Ibaraki 311- 0193 Japan

Immunological Effects of Silica and Asbestos

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Cellular & Molecular Immunology 2007年第4期4卷 261-268页

作者： takemi Otsuki Megumi Maeda Shuko Murakami Hiroaki Hayashi Yoshie Miura Masayasu Kusaka takashi Nakano Kazuya Fukuoka takumi kishimoto Fuminori Hyodoh Ayako Ueki Yasumitsu Nishimura Department of Hygiene Kawasaki Medical SchoolMatsushima 577Kurashiki 7010192Japan Eppley Institute for Cancer Research University of Nebraska Medical CenterOmahaNebraska 68198USA Department of Internal Medicine Kusaka Hospital1122 NishikatagamiBizen 7050021Japan Department of Respiratory Medicine Hyogo Medical College of Medicine1-1 Mukogawa-choNishinomiyaHyogo 6638131Japan Okayama Rosai Hospital 1-10-25 Chikkou-midori-machiOkayama 7028055Japan Department of Rehabilitation Faculty of Health Sciences and TechnologyKawasaki University of Medical Welfare288 MatsushimaKurashiki 7010193Japan Department of Nursing Kawasaki College of Allied Health Professions316 MatsushimaKurashiki 7010194Japan

Silicosis patients （SILs） and patients who have been exposed to asbestos develop not only respiratory diseases but also certain immunological disorders. In particular, SIL sometimes complicates autoimmune diseases such as systemic scleroderma, rheumatoid arthritis （known as Caplan syndrome）, and systemic lupus erythematoses. In addition, malignant complications such as lung cancer and malignant mesothelioma often occurr in patients exposed to asbestos, and may be involved in the reduction of tumor immunity. Although silica-induced disorders of autoimmunity have been explained as adjuvant-type effects of silica, more precise analyses are needed and should reflect the recent progress in immunomolecular findings. A brief summary of our investigations related to the immunological effects of silica/asbestos is presented. Recent advances in immunomolecular studies led to detailed analyses of the immunological effects of asbestos and silica. Both affect immuno-competent cells and these effects may be associated with the pathophysiological development of complications in silicosis and asbestos-exposed patients such as the occurrence of autoimmune disorders and malignant tumors, respectively. In addition, immunological analyses may lead to the development of new clinical tools for the modification of the pathophysiological aspects of diseases such as the regulation of autoimmunity or tumor immunity using cellmediated therapies, various cytokines, and molecule-targeting therapies. In particular, as the incidence of asbestosrelated malignancies is increasing and such malignancies have been a medical and social problem since the summer of 2005 in Japan, efforts should be focused on developing a cure for these diseases to eliminate nationwide anxiety.

关键词： silica asbestos immunology Fas regulatory t cell apoptosis