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Recovery of serum testosterone following neoadjuvant and adjuvant androgen deprivation therapy in men treated with prostate brachytherapy

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World Journal of Radiology 2015年第12期7卷 494-500页

作者： Hideyasu tsumura takefumi Satoh Hiromichi Ishiyama Shuhei Hirano Kenichi tabata Shinji Kurosaka Kazumasa Matsumoto tetsuo Fujita Masashi Kitano Shiro Baba Kazushige hayakawa Masatsugu Iwamura Department of Urology Kitasato University School of Medicine Department of Radiation Oncology Kitasato University School of Medicine

AIM: to investigate the time course of testosterone(t) recovery after cessation of androgen deprivation therapy(ADt) in patients treated with brachytherapy. MEtHODS: One-hundred and seventy-four patients treated between June 1999 and February 2009 were studied. Patients were divided into a short-term usage group(≤ 12 mo, n = 91) and a long-term usage group(≥ 36 mo, n = 83) according to the duration of gonadotropin-releasing hormone agonist therapy. Median follow-up was 29 mo in the short-term group and was 60 mo in the long-term ***: Cumulative incidence rates of t recovery to normal and supracastrate levels at 24 mo after cessationwere 28.8% and 74.6%, respectively, in the long-term usage group, whereas these values were 96.4% and 98.8% in the short-term usage group. t recovery to normal and supracastrate levels occurred significantly more rapidly in the short-term than in the long-term usage group(P tively). Five years after cessation, 22.6% of patients maintained a castrate t level in the long-term usage group. On multivariate analysis, lower t levels(t cessation of ADt was significantly associated with prolonged t recovery to supracastrate levels in the longterm usage group(P = 0.002). CONCLUSION: Lower t levels at cessation of ADt were associated with prolonged t recovery in the longterm usage group. Five years after cessation of longterm ADt, approximately one-fifth of patients still had castrate t levels. When determining the therapeutic effect, especially biochemical control, we should consider this delay in t recovery.

关键词： Androgen deprivation Gonadotropinreleasing hormone agonist Prostate brachytherapy Prostate cancer testosterone

关键核天体反应18Ne（α,ｐ）21Na的实验研究（英文）

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IMP & HIRFL Annual Report 2011年 52-53页

作者：张立勇 H. Yamaguchi S. Kubono Y. Wakabayashi Y. togano t. Hashimoto D. Kahl t. teranishi S. hayakawa N. Iwasa t. Yamada t. Komatsubara

A nuclear astrophysics experiment was performed at CRIB (CNS low-energy Radioactive-Ion Beam separator) on Mar. 2011. the goal of this experiment is to study the reaction rate of 18Ne(α, p)21Na reaction, which might be a key breakout reaction from the hot CNO cycle to rp-process in X-ray burst and nova. Yet its reaction rate is poorly known.

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^(126)Cs的高自旋态能级结构

高能物理与核物理 2004年第5期28卷 491-494页

作者：王守宇马英君 t. Komatsubara 刘运祚张玉虎梁国栋 K. Furuno t. hayakawa J. Mukai Y. Iwata t. Morikawa G. B. Hagcmann G. Sletten J. Nyberg D. Jerrestam H.J. Jensen J.Espino J. Gascon N. Gjrnp B.Cederwall P.O. tjm 吉林大学物理学院长春130023 Institute of Physics and tandem Accelerator Center 中国科学院近代物理研究所兰州730000 Department of Physics Department of Physics Faculty of Science Niels Bohr Institute Manne Siegbabn Institute of Physics

利用融合蒸发反应 116Cd(14 N ,4n) 12 6Cs布居了 12 6Cs的高自旋态 .观测到了 10 0多条新的γ跃迁和相应的能级 ,建立了双奇核 12 6Cs由 9个转动带构成的能级纲图 .尝试性地指定了大部分能级的自旋和宇称以及各转动带的Nilsson单粒子组... 详细信息

利用融合蒸发反应 116Cd(14 N ,4n) 12 6Cs布居了 12 6Cs的高自旋态 .观测到了 10 0多条新的γ跃迁和相应的能级 ,建立了双奇核 12 6Cs由 9个转动带构成的能级纲图 .尝试性地指定了大部分能级的自旋和宇称以及各转动带的Nilsson单粒子组态 .极大地丰富了已有的实验结果 .

关键词：铯原子高自旋态能级纲图转动带 Nilsson单粒子组态 γ跃迁

与地壳活动有关的ULF地磁变化:RIKEN-NASDA项目概要和最新结果

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世界地震译丛 2005年第3期36卷 50-53页

作者： K．Hattori I．takahashi M．hayakawa N．Isezaki K．Yumoto t．Nagao S．Uyeda 李琪杨冬梅不详中国地震局地球物理研究所

尽管地震短临预报极其重要,并且经过了人们多年的努力,但它仍是目前未能解决的问题。近年来,与地震相关的电磁现象被认为是解决地震短临预报的有效途径之一。现在已经积累了大量的地震电磁前兆信号的震例,这些信号分布在很宽的频带范围(... 详细信息

尽管地震短临预报极其重要,并且经过了人们多年的努力,但它仍是目前未能解决的问题。近年来,与地震相关的电磁现象被认为是解决地震短临预报的有效途径之一。现在已经积累了大量的地震电磁前兆信号的震例,这些信号分布在很宽的频带范围(DC-VHF)内,其中ULF地磁变化是最有希望的地磁前兆之一。通过监测ULF地磁变化,有望实现地震短临预报。本文将阐述从ULF电磁信号中提取震磁异常变化的方法。

关键词：地磁变化 ULF 地壳活动地震短临预报概要项目电磁现象前兆信号信号分布地磁前兆异常变化电磁信号震例震磁

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酶免疫法检测血清脂肪酶诊断胰腺疾病

临床消化病杂志 1990年第2期2卷 96-96页

作者： hayakawa t 谢小平

对41例正常对照组,76例胰腺疾患病人及60例非胰腺疾患病人用酶免疫法和比浊法测定血清脂肪酶及血清总淀粉酶,以评价血清免疫反应脂肪酶(IRL)诊断价值.血清IRL在13例急性胰腺炎病人中有12例升高.44例慢性胰腺炎中有12例升高,19例胰腺癌中... 详细信息

对41例正常对照组,76例胰腺疾患病人及60例非胰腺疾患病人用酶免疫法和比浊法测定血清脂肪酶及血清总淀粉酶,以评价血清免疫反应脂肪酶(IRL)诊断价值.血清IRL在13例急性胰腺炎病人中有12例升高.44例慢性胰腺炎中有12例升高,19例胰腺癌中有12例升高。血清IRL在44例慢性胰腺炎中9例降低,与晚期胰腺外分泌功能不全有关。在胰腺疾病中血清IRL的总敏感性为59％,比浊法为38％,血清淀粉酶为51％。在正常对照组与非胰腺疾病组的血清IRL特异性是80％,比浊法为86％,血清淀粉酶是88％.

关键词：胰腺疾病酶免疫法血清淀粉酶慢性胰腺炎比浊法胰腺外分泌功能血清脂肪酶胰腺炎病人血清免疫特异性

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年轻发病的COPD患者的临床特征

中华结核和呼吸杂志 1997年第Z1期20卷 100-100页

作者： toyoshima M Sato A tsuchiya t Sato J todate A tsukamoto K Morita S Imokawa S Nakano Y hayakawa H Chida K 叶藏(译) SecondDivision DepartmentfoInternalMedicineHamamatsuUniversitySchoolofMedicineHamamatsuJapan

Study of Multi-particle Excitations in 146tb

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IMP & HIRFL Annual Report 2004年 68-68页

作者： t. hayakawa,M. Oshima,t. toh,t. Shizuma,J. Katakura,Y. Hatsukawa,M. Matsuda,H. Kusakari,M. Sugawara Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Japan Atomic Energy Research Institute tokai Ibaraki 319-1195 Japan Chiba University Inage-ku Chiba 263-8512 Japan Chiba Institute of technology Narashino Chiba 275-0023 Japan

Study of in-beam γ-ray spectroscopy of 146tb has been carried out by using the 118Sn(32S,1p3n)146tb reaction. Based on the experimental measured results, the level scheme of 146tb has been revised significantly and extended up to an excitation energy of 8.39 MeV. Preliminary results of the present work have been reported in a letter. the level structure shows characteristics of a spherical nucleus. the odd-odd nucleus 146tb has one proton-particle and one neutron-hole with respect to the doubly closed nucleus 146Gd, and its low-

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脑室周围白质软化早产儿的闪光视觉诱发电位的发展变化过程

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世界核心医学期刊文摘（神经病学分册） 2005年第7期1卷 17-17页

作者： Kato t. Okumura A. hayakawa F. 江山 Department of Pediatrics Nagoya University Graduate School of Medicine 65 Tsurumai-cho Showa-ku Nagoya Aichi466-8550 Japan

Objective: the aim of this study was to prospectively investigate flash visual evoked potential (VEP) findings and their chronological changes in preterm infa nts with cystic periventricular leukomalacia (PVL) during the early neonatal per ***: the subjects of this study were 14 preterm infants with cystic PVL. the patients underwent serial cranial ultrasonography and diagnosed as having c ystic PVL. Flash VEPs were diagnosed at least twice within the first 3 weeks of ***: All infants had at least one or more flash VEP *** m ost common finding was ‘absent VEP’, which was seen in 13 infants (93%). ‘De layed latency’was seen in two infants and ‘abnormal waveform’was seen in one *** the chronological changes, all records were abnormal in 4 infa nts, and the other 10 had transient normal VEP findings. Among them, flash VEPs changed from normal to abnormal within 10 days after birth in most cases. Conclu sions:Almost all infants with cystic PVL had abnormal flash VEPs within the firs t 3 weeks of life, but chronological changes of flash VEP findings were seen dur ing the period. Significance:this manuscript may be useful as a reference to the flash VEP sin preterm infants with cystic PVL.

关键词：脑超声波检查新生儿期发展变化过程出生后 neonatal evoked twice abnormal cranial birth

Study of Multi-particle Excitations in ^(146)tb

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2004年第1期 47-47页

作者： Xie Chengying Zhou Xiaohong Zheng Yong Zhang Yuhu Liu Zhong t. hayakawa M. Oshima t. toh t. Shizuma J. Katakura Y. Hatsukawa M. Matsuda H. Kusakari M. Sugawara japan Atomic Energy Research Institute Tokai Ibaraki 319-1195 Japan. Chiba University Inage-ku Chiba 263-8512 Japan. Chiba Institute of technology Narashino Chiba 275-0023 Japan.

关键词：激发能量多粒子实验测量层次结构 MCV 水