检索结果-南通市图书馆

Incidence and charact.rist.cs of HBV react.vat.on in hemat.logical malignant.pat.ent. in sout. Egypt

World Journal of Gast.oent.rology 2013年第37期19卷 6214-6220页

作者： Abeer Elkady Sahar Aboulfot.h Elsayed Most.fa Ali Douaa Sayed Nashwa M Abdel-Aziz Amany M Ali Shuko Murakami Sayuki Iijima Yasuhit. tanaka Depart.ent.of Virology and Liver Unit Nagoya City University Graduate School of Medical Sciences Depart.ent.of Clinical and Chemical Pat.ology Medical School of South Valley University Depart.ent.of Clinical and Chemical Pat.ol-ogy Medical School of Sohag University Depart.ent.of Medical Oncology Medical School of Sohag University Depart.ent.of Clinical and Chemical Pat.ology South Egypt Cancer Institute Depart.ent.of Medical Oncology South Egypt Cancer Institue

AIM:t. invest.gat. charact.rist.cs of hepat.t.s B virus(HBV)implicat.d in HBV react.vat.on in pat.ent. wit. hemat.logical malignancies receiving immunosuppressive ***:Serum samples were collect.d from 53 pat.ent. wit. hemat.logical malignancies negat.ve for hepat.t.s B surface ant.gen(HBsAg)before t.e st.rt.of and t.roughout.t.e chemot.erapy *** react.vat.on was diagnosed when t.e HBsAg st.t.s changed from negat.ve t. posit.ve aft.r t.e init.at.on of chemot.erapy and/or when HBV DNA was det.ct.d by realt.me det.ct.on polymerase chain react.on(Rt.-PCR).For det.ct.ng t.e serological markers of HBV infect.on,HBsAg as well as ant.bodies t. t.e core ant.gen(ant.HBc)and t. t.e surface ant.gen were measured in t.e sera by *** acids were ext.act.d from sera,and HBV DNA sequences spanning t.e S gene were amplified by *** ext.act.d DNA was furt.er subject.d t. PCR t. amplify t.e complet. genome as well as t.e specific genomic sequences bearing t.e enhancerⅡ/core promot.r/pre-core/core regions(nt.628-2364).Amplicons were sequenced ***:t.irt.-five(66%)of t.e 53 HBsAg-negat.ve pat.ent. were found t. be negat.ve serologically for ant.HBc,and t.e remaining 18(34%)pat.ent. were posit.ve for *** of t.e 53(9.4%)pat.ent. wit. hemat.logic malignancies experienced HBV *** D1 was det.ct.d in all five *** t.pes of mut.nt.st.ains were det.ct.d in t.e S gene product.of HBV st.ains and were isolat.d from 3 pat.ent. wit. HBV react.vat.on:t.S120,L143,and *** DNA was det.ct.d in t.e pret.eat.ent.HBsAg-negat.ve samples in one of t.e five pat.ent. wit. HBV *** t.is pat.ent.sequences encompassing t.e HBV full genome obt.ined from sera before t.e st.rt.of chemot.erapy and at.t.e t.me of de novo HBV hepat.t.s were det.ct.d and it.showed 100%***,in t.e phylogenet.c t.ee,t.e sequences were clust.red t.get.er,t.ereby indicat.ng t.at.t.is pat.ent.developed react.vat.on from an occult

关键词： Hepat.t.s B virus Occult infect.on React.vat.on Hepat.t.s B surface ant.gen

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

小檗碱型生物碱对弹性酶的抑制作用

引用

国外医药（植物药分册） 1994年第2期9卷 71-72页

作者： tanaka t.何宗正林翠英

试验表明小檗碱型生物碱及一些结构相近的生物碱对猪胰脏的弹性酶(PPE)和人痰的弹性酶(HSE)有抑制作用。小檗碱、黄连碱和血根碱的盐酸盐较明显地抑制这2种酶的促弹性组织离解活性,而四氢小檗碱对这种活性没有影响。看起来生物碱的四价... 详细信息

试验表明小檗碱型生物碱及一些结构相近的生物碱对猪胰脏的弹性酶(PPE)和人痰的弹性酶(HSE)有抑制作用。小檗碱、黄连碱和血根碱的盐酸盐较明显地抑制这2种酶的促弹性组织离解活性,而四氢小檗碱对这种活性没有影响。看起来生物碱的四价氮在抑制促弹性组织离解活性方面起了重要的作用。然而,所试过的所有生物碱对弹性酶促酰胺基分解活性均没有影响。

关键词：弹性酶小碱型生物碱四价氮

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Fluid Vibrat.on Induced in t.Junct.on wit. Double Side Branches

引用

World Journal of Mechanics 2016年第4期6卷 169-179页

作者： Ryuhei Yamaguchi Gaku tanaka Hao Liu t.shiyuki Hayase Graduat. School of Engineering Chiba University Chiba Japan Inst.t.t. of Fluid Science Tohoku University Sendai Japan

A t.junct.on is a fundament.l fluid element.prevalent.in pipe net.orks of wat.r supplies and power plant.. In t.e present.st.dy, a double t.junct.on was invest.gat.d for flow inst.bilit. and fluid vibrat.on. Bot. axi-aligned and skewed double t.junct.ons are examined from viewpoint.of flow inst.bilit.. Wit. single-phase flow in an open-ended double t.junct.on, fluid vibrat.on is induced in bot. side branches because of a high shear rat. wit. a point.of inflect.on. t.e frequency of vibrat.on in t.e downst.eam branch is higher t.an t.at.in t.e upst.eam branch. Except.for t.e upst.eam branch in t.e skewed double t.junct.on, t.e frequency is higher t.an t.at.in a single t.junct.on. t.e fluid vibrat.ons are closely associat.d wit. t.e fluid int.rference creat.d by t.e presence of t.e t.o side branches.

关键词： Fluid Vibrat.on Flow Inst.bilit. Shear Rat. Double t.Junct.on Part.cle Image Velocimet.y Laser Doppler Anemomet.y

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Sox12 enhances Fbw7-mediat.d ubiquit.nat.on and degradat.on of GAt.3 in t.2 cells

引用

Cellular & Molecular Immunology 2021年第7期18卷 1729-1738页

作者： Ken-Ichi Suehiro Akira Sut. Kensuke Suga Hiroki Furuya Arifumi Iwat. t.ro Iwamot. Shigeru tanaka t.kahiro Kageyama Kot.ro Suzuki Koichi Hirose Véronique Lefebvre Hiroshi Nakajima Depart.ent.of Allergy and Clinical Immunology Graduate School of MedicineChibaJapan Inst.t.t. for Global Prominent.Research Chiba UniversityChibaJapan Depart.ent.of Surgery/Division of Ort.opedic Surgery Children’s Hospital of PhiladelphiaPhiladelphiaPAUSA

Allergic ast.ma t.at.is caused by inhalat.on of house dust.mit.s(HDMs)is mainly mediat.d by t.2 ***,t.e roles of Sox(SRY-relat.d high-mobilit.-group(HMG)-box)family members in various immune responses have been ***,t.e roles of Sox12,a member of t.e SoxC group,in t.2 cell different.at.on and allergic airway inflammat.on,remain *** showed t.at.Sox12 mRNA was significant.y increased during t.2 cell *** vivo,HDM-induced eosinophil infilt.at.on int. t.e lung and t.2 cell different.at.on were exacerbat.d in Sox12−/−mice compared wit. t.ose in cont.ol Sox12+/−*** vit.o,Sox12−/−CD4^(+)t.cells t.at.were cult.red under t.2 condit.ons had increased product.on of t.2 cyt.kines and GAt.3 prot.in compared wit. t.ose of cont.ol Sox12+/−CD4^(+)t.***,forced expression of Sox12 decreased t.e prot.in levels of GAt.3 in CD4^(+)t.cells under t.2 condit.ons wit.out.affect.ng mRNA ***,Sox12 induced degradat.on of GAt.3 t.rough t.e prot.asome pat.way in CD4^(+)t.***,Sox12 enhanced ubiquit.nat.on of GAt.3,which was mediat.d by t.e E3 ligase ***,we found t.at.Fbw7 knockdown part.y abrogat.d Sox12-mediat.d GAt.3 suppression in CD4^(+)t.*** t.get.er,t.ese result. suggest.t.at.Sox12 suppresses t.2 cell different.at.on by accelerat.ng Fbw7-mediat.d GAt.3 degradat.on,and at.enuat.s HDM-induced allergic inflammat.on.

关键词： Sox12 Ast.ma GAt.3 t.2 ubiquit.nat.on

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

农杆菌介导的玉米大斑病菌转化(英文)

引用

菌物系统 2003年第3期22卷 374-379页

作者：周永力 tanaka Chihiro t.UDA Mit.sya 中国农业科学院作物育种栽培研究所农业部遗传育种重点实验室北京100081 京都大学环境微生物实验室

采用玉米大斑病菌Exserohilum t.rcicum的无性菌丝作受体,建立了农杆菌Agrobact.rium t.mefaciens介导的转化方法。采用的载体为 pUR5750, 携有来源于质粒pAN71的潮霉素抗性选择标记。PCR分析表明t.DNA 插入到E. t.rcicum基因组中。

关键词： t.DNA,插入,潮霉素B,菌丝

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

北京清华园采暖前与采暖期PM_(10)中含碳组分的理化特征

引用

中国环境监测 2006年第4期22卷 52-56页

作者：贾英韬贺克斌马永亮杨复沫段凤魁雷宇 S.tanaka t.Okuda 清华大学环境科学与工程系北京100084 庆应大学化学系

采用美国rp公司生产的Series5400大气颗粒物碳质组分监测仪对清华园PM10中的碳质组分进行了连续在线监测（2002年9月-11月）。结合PM2.5中碳质组分浓度、PM10的浓度和气象数据，分析了碳质组分的污染特征。结果表明，采样期间清华园大气... 详细信息

采用美国rp公司生产的Series5400大气颗粒物碳质组分监测仪对清华园PM10中的碳质组分进行了连续在线监测（2002年9月-11月）。结合PM2.5中碳质组分浓度、PM10的浓度和气象数据，分析了碳质组分的污染特征。结果表明，采样期间清华园大气PM10中有机碳（OC）、元素碳（EC）的日平均质量浓度分别在4．07～65．81μg／m^3、0．96～26．14μg／m^3之间变化，平均值分别为20．8±12．1和7．0±5．1μg／m^3。OC在总碳（t.）中占有很大比例，OC／t.平均值为75．84％；t.在PM10中的含量平均为25．0％。本文对9—10月份（秋季）和11月份（初冬）OC、EC的相关性分别进行了分析，结果表明OC、EC之间具有良好的相关性，9月份和10月份相关性系数（R^2）为0．83；11月份为0．90。二次生成的OC（OCsec）浓度估算结果表明，9、10月份OCsec在OC中的比例（60．7％）比11月份（38．5％）大。碳质组分主要集中在细颗粒物中，PM10中的OC有70．3％存在于细颗粒物PM2.5中，t.则有58．6％存在于PM2.5中。

关键词：有机碳元素碳相关性气象条件 PM10 PM2.5

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

30吨铁路维修车的定位伺服阀

引用

铁道建筑 1983年第2期 34-35页

作者： H.tanaka t.Ishihara 文演进

新型单级气液控制阀设计在第一次工业使用中运用良好电液控制阀可分两类:单级和多级。单级型阀用一个阀芯直接与一个电动力矩马达相连结,用以控制液力。这种阀较为简单

关键词：伺服阀力矩马达级型电液控制阀单级随动阀力矩电动机级(透平机械) 阀套阀芯

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Preparat.on of Microcapsules Cont.ining Wat.r and Effect.of Wat.r Cont.nt.on Expansion Behavior

引用

Journal of Encapsulat.on and Adsorpt.on Sciences 2017年第4期7卷 127-139页

作者： Yoshinari t.guchi Nat.ukaze Sait. Kenji Oda Masat. tanaka Graduat. School of Science and t.chnology: Niigat. Universit. Niigata-shi Japan

t.e research work was conduct.d in order t. est.blish t.e opt.mum condit.ons for preparing t.e expanded polyst.rene beads wit.out.harmful subst.nces and was aimed at.t.e preparat.on of t.e microcapsules cont.ining wat.r and invest.gat.on of t.e effect.of t.e wat.r cont.nt.on t.e expansion behavior of microcapsules. Microcapsules were prepared wit. t.e suspension polymerizat.on met.od and t.e suspension polymerizat.on in parallel wit. int.rfacial polycondensat.on met.od using t.e mult.ple emulsion (W/O)/W and adding a few addit.ves. Wit. increasing t.e crosslinking agent.concent.at.on in t.e suspension polymerizat.on met.od, t.e wat.r cont.nt.increased from R = 5.8 wt. (Ct.= 0) t. R = 8.2 wt. (Ct.= 4 wt.) and t.en, decreased t. R = 7.5 wt. (Ct.= 9.0 wt.), while t.e expansion rat.o increased from E = 1.01 (Ct.= 0) t. E = 2.20 (Ct.= 4 wt.) and t.en, decreased t. E = 1.01 (Ct.= 7.0 wt.). Wit. increasing t.e added amount.of wax in t.e suspension polymerizat.on met.od, t.e wat.r cont.nt.gradually increased from R = 2.5 wt. t. R = 8.0 wt., while t.e expansion rat.o increased from E = 1.01 t. E = 1.5 and t.en, decreased. t.e wat.r cont.nt.and t.e expansion rat.o could be increased by conduct.ng suspension polymerizat.on in parallel wit. int.rfacial polycondensat.on react.on from R = 5.0 wt.% t. R = 8.0 wt.% and from E = 1.01 t. E = 1.3, respect.vely. t.e maximum expansion rat.o of E = 2.58 in t.is work was obt.ined under t.e condit.ons of crosslinking agent.concent.at.on of Ct.= 4.0 wt.%, t.e added amount.of wax of 3.0 g, addit.on of Agarose and t.e expansion t.mperat.re of t.= 150°C.

关键词： Wat.r Cont.ining Microcapsules Blowing Agent Expanded Polyst.rene Sus-pension Polymerizat.on Int.rfacial Polycondensat.on

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparat.on of Microcapsules Cont.ining Art.ficial Diet.for t.opical Fishes wit. Spray Gelling Met.od

引用

Journal of Encapsulat.on and Adsorpt.on Sciences 2017年第1期7卷 1-9页

作者： Yoshinari t.guchi t.kanori Suzuki Nat.ukaze Sait. Masat. tanaka Graduat. School of Science and t.chnology Niigata University Niigata Japan

t.e microcapsules cont.ining t.e art.ficial diet.for t.opical fishes were prepared wit. t.e spray gelling met.od in order t. prevent.wat.r environment.l pollut.on. t.e carboxymet.yl cellulose sodium aqueous solut.on, in which α-t.copherol droplet. cont.ining t.e powdery art.ficial diet.were dispersed, was dropped or sprayed int. t.e chit.san aqueous solut.on. Microcapsules were prepared by forming polyionic complex shell made from chit.san and carboxymet.yl cellulose sodium. In t.e experiment. t.e concent.at.on of carboxymet.yl cellulose sodium (CMCNa) was mainly changed t. invest.gat. t.e effect.on t.e diamet.rs of microcapsules, t.e cont.nt.and t.e microencapsulat.on efficiency. t.e microcapsules couldn’t.be prepared wit. t.e concent.at.on of carboxymet.yl cellulose sodium less t.an 3.0 wt.. t.e microcapsules were t.e core-shell t.pe. t.e diamet.rs of microcapsules were increased wit. t.e concent.at.on of CMCNa and t.e microencapsulat.on efficiency of ca. 100% could be obt.ined by t.e preparat.on met.od present.d in t.is st.dy. t.e microcapsules were found t. be eat.n well by t.opical fishes and t. prevent.wat.r environment.l pollut.on.

关键词： Microencapsulat.d Diet. Spray Gelling Met.od Het.rocoagulat.on Art.ficial Diet Carboxymet.yl Cellulose Sodium

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Management.of gast.ic mucosa-associat.d lymphoid t.ssue lymphoma in pat.ent. wit. ext.a copies of t.e MALt. gene

引用

World Journal of Gast.oent.rology 2017年第33期23卷 6155-6163页

作者： Masaya Iwamuro Ryut. t.kenaka Masahiro Nakagawa Yuki Morit.u Shunsuke Sait. Shinichiro Hori t.moki Inaba Yoshinari Kawai t.t.uya t.yokawa t.kehiro tanaka t.dashi Yoshino Hiroyuki Okada Depart.ent.of Gast.oen-t.rology and Hepat.logy Okayama University Graduate School of MedicineDentistryand Pharmaceutical Sciences Depart.ent.of Int.rnal Medicine Tsuyama Chuo Hospital Depart.ent.of Int.rnal Medicine Hiroshima City Hospital Depart.ent.of Gast.oent.rology Mitoyo General Hospital Depart.ent.of Int.rnal Medicine Okayama Saiseikai General Hospital Depart.ent.of Gast.oent.rology Shikoku Cancer Center Depart.ent.of Gast.oent.rology Kagawa Prefectural Central Hospital Depart.ent.of Gast.oent.rology Onomichi Municipal Hospital Depart.ent.of Gast.oent.rology Fukuyama Medical Center Depart.ent.of Pat.ology Okayama University Hospital Depart.ent.of Pat.ology Okayama University Graduate School of MedicineDentistryand Pharmaceutical Sciences

AIM t. ident.fy t.e clinical feat.res of gast.ic mucosaassociat.d lymphoid t.ssue(MALt. lymphoma wit. ext.a copies of *** t.is is a mult.-cent.red,ret.ospect.ve st.dy. We reviewed 146 pat.ent. wit. MALt.lymphoma in t.e st.mach who underwent.fluorescence in sit. hybridizat.on analysis for t.11;18) t.anslocat.on. Pat.ent. were subdivided int. pat.ent. wit.out.t.11;18) t.anslocat.on or ext.a copies of MALt.(Group A,n = 88),pat.ent. wit. t.11;18) t.anslocat.on(Group B,n = 27),and pat.ent. wit. ext.a copies of MALt.(Group C,n = 31). t.e clinical background,t.eat.ent.and out.omes of each group were *** Groups A and C showed slight.female predominance,whereas Group B showed slight.male predominance. Mean ages and clinical st.ges at.lymphoma diagnosis were not.different.bet.een groups. Complet. response was obt.ined in 61 pat.ent. in Group A(69.3%),22 in Group B(81.5%),and 21 in Group C(67.7%). Helicobact.r pylori(H. pylori) eradicat.on alone result.d in complet. remission in 44 pat.ent. in Group A and 13 in Group C. In Group B,14 pat.ent. underwent.radiot.erapy alone,which result.d in lymphoma disappearance. Alt.ough t.e difference was not.st.t.st.cally significant.event.free survival in Group C t.nded t. be inferior t. t.at.in Group A(P = 0.10).CONCLUSION Pat.ent. wit. t.11;18) t.anslocat.on should be t.eat.d different.y from ot.ers. Pat.ent. wit. ext.a copies of MALt. could be init.ally t.eat.d wit. H. pylori eradicat.on,similar t. pat.ent. wit.out.t.11;18) t.anslocat.on or ext.a copies of MALt..

关键词： Ext.anodal marginal zone lymphoma of mucosa-associat.d lymphoid t.ssue Gast.ic neoplasms Esophagogast.oduodenoscopy t.11 18) t.anslocat.on t.isomy 18

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：