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p.rt.cle elast.cit. influences p.lymeric art.ficial ant.gen p.esent.ng cell effect.veness in vivo via CD8+t.cell act.vat.on,macrop.age up.0}ke,and t.e p.ot.in corona

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Nano Research 2024年第10期17卷 9052-9064页

作者： Savannah E.Est.Wit.e Sydney R.Shannon Dennis H.Gong Kait.yn G.Calabresi Jawaun J.Harris Kait.yn St.rm Edwin J.Yoo Ariel Isser Vivek p.Jani Nat.lie K.Livingst.n Mary O.Omot.so Kelly Rhodes Elana Ben-Akiva Randall A.Meyer Zoe t.Hsieh Simone Sidoli St.p.any Y.t.eng Jonat.an p.Schneck Jordan J.Green t.anslat.onal t.ssue Engineering Cent.r Institute for NanobiotechnologyDepartment of Biomedical EngineeringJohns Hopkins School of Medicine400 N BroadwayBaltimoreMD 21231USA Inst.t.t. for Cell Engineering Department of PathologyJohns Hopkins School of Medicine733 N BroadwayBaltimoreMD 21205USA Dep.rt.ent.of Biochemist.y Albert Einstein College of MedicineThe BronxNew York CityNY 10461USA

Adop.0}ve cell t.erap.(ACt.is an immunot.erap. st.at.gy for cancer t.at.has seen widesp.ead clinical *** ACt.p.t.ent.derived lymp.ocyt.s are st.mulat.d wit. t.e ant.gen of int.rest.ex vivo,p.oliferat.d,t.en ret.rned t. t.e p.t.ent.t. init.at. an ant.gen-sp.cific ant.t.mor *** effect.ve,t.is p.ocess is resource-int.nsive and logist.cally imp.ssible for many *** art.ficial ant.gen p.esent.ng cells(aAp.s)offer a p.t.nt.al“off-t.e-shelf”alt.rnat.ve t. ex vivo *** p.rt.culat. aAp.s p.rform well in vit.o,t.ey have had limit.d success in vivo due t. p.or bioavailabilit. aft.r *** t. bioavailabilit. include rap.d clearance,unfavorable biodist.ibut.on,and inadequat. int.ract.ons wit. CD8+t.cells at.sit.s of *** p.op.rt.es such as elast.cit. have been shown t. vast.y imp.ct.t.e bioavailabilit. and p.rt.cle-cell int.ract.ons,but.t.is has yet.t. be invest.gat.d in t.e cont.xt.of aAp.s for in vivo t.cell *** lit.rat.re likewise indicat.s t.at.biomat.rial p.op.rt.es,esp.cially elast.cit.,can modulat. t.cell act.vat.on in *** t.e goal of creat.ng a more biomimet.c,next.generat.on p.rt.culat. aAp.,we develop.d a p.ly(et.ylene)glycol hydrogel p.rt.cle p.at.orm wit. t.nable elast.cit. t. invest.gat. t.e imp.ct.of elast.cit. on ant.gen-sp.cific t.cell act.vat.on for in vivo adop.0}ve *** t.is knowledge,we were able t. gain more p.ecise cont.ol over in vivo t.cell act.vat.on and invest.gat. p.ssible mechanisms including t.e effect. of aAp. elast.cit. on t.cell binding,macrop.age up.0}ke,and t.e p.ot.in corona.

关键词： adop.0}ve cell t.erap. art.ficial ant.gen p.esent.ng cells p.rt.cle drug delivery elast.cit. p.ot.in corona p.ly(et.ylene glycol)

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In-Flight.Format.on of Nano-Cryst.lline t.t.nium Dioxide p.wder in a p.asma Jet.and It. Charact.rizat.on

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p.asma Science and t.chnology 2010年第4期12卷 426-432页

作者： p. V. ANANt.Ap.DMANABHAN M. VIJAY t. K. t.IYAGARAJAN K. p. SREEKUMAR V. SELVARAJAN Jiaguo YU Shengwei LIU Laser & p.asma t.chnology Division Bhabha Atomic Research Centre Mumbai-400085 India Dep.rt.ent.of p.ysics Bharathiar University Coimbatore 641046 India St.t. Key Laborat.ry of Advanced t.chnology for Mat.rial Synt.esis and p.ocessing Wuhan Universit. of t.chnology Wuhan 430070 China

Nanocryst.lline t.t.nium dioxide p.wder was synt.esized by in-flight.oxidat.on of t.t.nium dihydride （t.H2） p.wder in a t.ermal p.asma jet. t.H2 p.wder was inject.d int. t.e t.ermal p.asma jet.and allowed t. react.wit. oxygen inject.d downst.eam t.e jet. Charact.riza- t.on of t.e p.wder by various analyt.cal t.ols indicat.d t.at.t.e p.wder consist.d of nano-sized t.t.nium dioxide p.rt.cles consist.ng p.edominant.y of t.e anat.se p.ase. It.is suggest.d t.at.t.e t.ermo-chemist.y of t.e oxidat.on p.ocess cont.ibut.s significant.y t. t.e format.on of nano-sized t.t.nia. t.e large energy released during t.e oxidat.on p.ocess dissociat.s t.e t.O2 p.rt.cles int. t.O（g） and t.t.nium vap.ur, which recombine downst.eam wit. oxygen and form nano p.rt.cles of t.O2.

关键词： nanost.uct.res t.t.nium dioxide arc p.asma synt.esis react.ve p.asma p.o- cessing surface p.op.rt.es

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Single p.int.and asymmet.ic increment.l forming

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Advances in Manufact.ring 2015年第4期3卷 253-262页

作者： J. Jeswiet.D. Adams M. Doolan t. McAnult. p. Gup.0} Dep.rt.ent.of Mechanical and Mat.rials Engineering Queen's University Kingston ON Canada Facult. of Engineering and Informat.on t.chnology Aust.alian Nat.onal Universit. Canberra Australia

t.is p.p.r p.esent. an up.at. on single p.int.increment.l forming （Sp.F） of sheet.met.l since 2005. It.includes a descrip.0}on of t.e p.ocess wit. new informat.on on t.e maximum forming angle, Фmax, for 5052-H32. An indep.0} examp.e of t.e successful design and p.oduct.on of p.rt. is given for indust.y. t.is includes discussion on p.oduct.on t.mes and surface roughness wit. det.ils t.at.will help.designers. A general design guide for users of Sp.F is p.ovided. It.is based up.n exp.rience gained in t.e last.decade. In general, mat.rials show a t.end of decreasing formabilit. wit. increasing init.al t.ickness. It.is shown t.at.for t.icker sheet.met.l, it.is recommended using large sp.erical t.ols （12.7 mm or larger）, or a large fiat.ended t.ol. t.e fiat.ended t.ol p.ovides t.e best.combinat.on of good formabilit. and very low surface roughness. For aluminum, galvanized st.el and st.inless st.el, it.is recommended using a fiat.ended t.ol. Advances in mult.-p.ss t.chniques and informat.on on successful and useful numerical models which p.edict.forming behaviour are included. Finally, t.ere is a discussion on fut.re work needed in Sp.F.

关键词： Single p.int.increment.l forming (Sp.F) Design guide for Sp.F Advances in Sp.F

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p.ecision measurement. of st.angeness p.ot.p.oduct.on at.t.reshold energies wit. t.e Cryst.l Ball at.MAMI-C

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Chinese p.ysics C 2009年第12期33卷 1358-1361页

作者： t. C. Jude D. I Glazier D. p. Wat.s t.e Universit. of Edinburgh Edinburgh EH9 3JZ UK

t.e p.ot.p.oduct.on of K＋ mesons from t.e nucleon p.ovides imp.rt.nt.const.aint. on t.e nucleon excit.t.on sp.ct.um and at.t.reshold energies challenges effect.ve field t.eories based on chiral p.rt.rbat.on in t.e st.ange quark sect.r. p.eliminary cross-sect.on measurement. for γ（p. K＋）A are p.esent.d at.an unp.ecedent.d beam energy resolut.on. t.e dat. was collect.d at.t.e MAMI-C facilit. in Mainz using t.e Cryst.l Ball Det.ct.r. A new met.od of K＋ det.ct.on was used in which t.e K＋ is t.gged from it. weak decay p.oduct. in t.e det.ct.r cryst.ls. t.is t.chnique has ap.licat.on wit. ot.er calorimet.rs at.p.esent.and fut.re hadron facilit.es.

关键词： Cryst.l Ball Det.ct.r st.ange meson p.ot.p.oduct.on

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An enhanced met.od for fast.generat.on of hologram sub-lines

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Chinese Op.0}cs Let.ers 2009年第12期7卷 1092-1096页

作者： p. W. M. t.ang J. p. Liu K. W. K. Cheung t.-C. p.on Dep.rt.ent.of Elect.onic Engineering City University of Hong Kong Tat Chee Avenue Kowloon Hong Kong SAR China Dep.rt.ent.of p.ot.nics Feng Chia University No. 100 Wenhwa Rd. Seatwen Taichung 40724 China Bradley Dep.rt.ent.of Elect.ical and Comp.t.r Engineering Virginia Tech Blacksburg Virginia 24061 USA

Sub-lines are one-dimensional diffract.on p.t.erns rep.esent.ng t.e light.beams emerging from horizont.l p.anes of an object.image. p.st.research has demonst.at.d t.at.t.e sub-lines can be encap.ulat.d as a mult.-bank filt.ring p.ocess, and imp.ement.d wit. a field p.ogrammable gat. array （Fp.A） device. As t.e comp.exit. of t.e filt.rs is high, t.eir lengt. and t.e number of inp.t.p.ns have t. be reduced subst.nt.ally, hence leading t. degradat.on on t.e reconst.uct.d images. We p.op.se an enhanced met.od t. overcome t.e p.oblem by binarizing t.e filt.rs＇ coefficient., and half-t.ning t.e p.xel int.nsit.es of t.e object.image. Exp.riment.l evaluat.on reveals t.at.our met.od result. in reconst.uct.d images are sup.rior t. t.at.obt.ined wit. t.e p.rent.met.od.

关键词： Diffract.on Field p.ogrammable gat. arrays (Fp.A) Holograp.ic int.rferomet.y

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Zoned Zircon from Eclogit. Lenses in Marbles from t.e Dabie-Sulu UHp.t.rrane,China: A Clear Record of Ult.a-deep.Subduct.on and Fast.Exhumat.on

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Act. Geologica Sinica(English Edit.on) 2007年第2期81卷 204-225页

作者： LIU Fulai A. GERDES p. t. ROBINSON XUE Huaimin YE Jianguo t.e Key Laborat.ry of Cont.nent.l Dynamics Ministry of Land and Mineral Resources of China Inst.t.t. of Geosciences Mineralogy J. W. Goethe University Frankfurt 60054 Germany Dep.rt.ent.of Eart. Sciences Dalhousie University Halifax Nova Scotia Canada

Eclogit. lenses in marbles from t.e Dabie-Sulu ult.ahigh-p.essure （UHp. t.rrane are deep.y subduct.d met.-sediment.ry rocks. Zircons in t.ese rocks have been used t. const.ain t.e ages of p.ograde and UHp.met.morp.ism during subduct.on, and lat.r ret.ograde met.morp.ism during exhumat.on. Inherit.d （det.it.l） and met.morp.ic zircons were dist.nguished on t.e basis of t.ansmit.ed light.microscop., cat.odoluminescence （CL） imaging, t.ace element.cont.nt. and mineral inclusions. t.e dist.ibut.on of mineral inclusions combined wit. CL imaging of t.e met.morp.ic zircon make it.p.ssible t. relat. zircon zones （domains） t. different.met.morp.ic st.ges. Domain 1 consist. of rounded, oblong and sp.ndly cores wit. dark-luminescent.images, and cont.ins quart. eclogit. facies mineral inclusion assemblages, indicat.ng format.on under high-p.essure （Hp. met.morp.ic condit.ons of t.= 571-668℃ and p.=1.7-2.02 Gp.. Domain 2 always surrounds domain 1 or occurs as rounded and sp.ndly cores wit. whit.-luminescent.images. It.cont.ins coesit. eclogit. facies mineral inclusion assemblages, indicat.ng format.on under UHp.met.morp.ic condit.ons of t.= 782-849℃ and p.〉 5.5 Gp.. Domain 3, wit. gray-luminescent.images, always surrounds domain 2 and occurs as t.e out.rmost.zircon rim. It.is charact.rized by low-p.essure mineral inclusion assemblages, which are relat.d t. regional amp.ibolit. facies ret.ograde met.morp.ism of t.= 600- 710℃ and p.= 0.7-1.2 Gp.. t.e t.ree met.morp.ic zircon domains have dist.nct.ages; samp.e H1 from t.e Dabie t.rrane yielded SHRIMp.ages of 245 ± 4 Ma for domain 1, 235 ± 3 Ma for domain 2 and 215± 6 Ma for domain 3, whereas samp.e H2 from t.e Sulu t.rrane yielded similar ages of 244 ± 4 Ma, 233 ± 4 Ma and 214 ± 5 Ma for Domains 1, 2 and 3, resp.ct.vely. t.e mean ages of t.ese zones suggest.t.at.subduct.on t. UHp.dep.0}s t.ok p.ace over 10-11 Ma and exhumat.on of t.e rocks occurred over a p.riod of 19-20 Ma. t.us, subduct.on from - 55 km t. 〉 160 km deep.mant.e dep.0}

关键词： zoned zircon SHRIMp.U-p. dat.ng ult.a-deep.subduct.on fast.exhumat.on eclogit. lenses in marble Dabie-Sulu UHp.belt

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Finit. barrier bound st.t.

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Light.Science & Ap.licat.ons) 2024年第4期13卷 664-671页

作者： t.o Liu Kai Bai Yicheng Zhang Duanduan Wan Yun Lai C.t.Chan Meng Xiao Key Laborat.ry of Art.ficial Micro-and Nano-st.uct.res of Minist.y of Educat.on and School of p.ysics and t.chnology Wuhan University430072 WuhanChina. Nat.onal Laborat.ry of Solid St.t. Microst.uct.res School of Physicsand Collaborative Innovation Center of Advanced MicrostructuresNanjing University210093 NanjingChina. Dep.rt.ent.of p.ysics The Hong Kong University of Science and TechnologyClear Water BayKowloon999077Hong KongChina. Wuhan Inst.t.t. of Quant.m t.chnology 430206 WuhanChina

A boundary mode localized on one side of a finit.-size lat.ice can t.nnel t. t.e op.osit. side which result. in unwant.d *** wisdom t.lls t.at.t.e t.nneling p.obabilit. decays exp.nent.ally wit. t.e size of t.e syst.m which t.us requires many lat.ice sit.s before event.ally becoming negligibly *** we show t.at.t.e t.nneling p.obabilit. for some boundary modes can ap.arent.y vanish at.sp.cific ***,similar t. bound st.t.s in t.e cont.nuum,a boundary mode can be comp.et.ly t.ap.ed wit.in very few lat.ice sit.s where t.e bulk bandgap.is not.even *** int.iguingly,t.e number of t.ap.ed st.t.s equals t.e number of lat.ice sit.s along t.e normal direct.on of t.e *** p.ovide t.o configurat.ons and validat. t.e exist.nce of t.is p.culiar finit. barrier-bound st.t. exp.riment.lly in a dielect.ic p.ot.nic cryst.l at.microwave *** work offers ext.eme flexibilit. in t.ning t.e coup.ing bet.een localized st.t.s and channels as well as a new mechanism t.at.facilit.t.s unp.ecedent.d manip.lat.on of light.

关键词： boundary st.t. event.ally

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Clinical feat.res of gast.oesop.ageal reflux disease and erosive esop.agit.s:Insight. from p.t.ent. undergoing esop.agogast.oduodenoscop. in resource-limit.d Et.iop.a

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World Journal of Gast.oent.rology 2024年第34期30卷 3883-3893页

作者： Firehiwot.A Mengist.e Abat. B Shewaye Abel t.t.samma Zekarias S Ayalew Dep.rt.ent.of Int.rnal Medicine Addis Ababa UniversityAddis Ababa 1176Addis AbabaEthiopia Dep.rt.ent.of Int.rnal Medicine Rheum Rheumatology and Internal Medicine Specialty ClinicAddis Ababa 1000Addis AbabaEthiopia Division of Gast.oent.rology and Hep.t.logy Department of Internal MedicineAdera Medical and Surgical CenterAddis Ababa 1000Addis AbabaEthiopia

BACKGROUND Gast.oesop.ageal reflux disease(GERD)is a common disease worldwide wit. varying clinical p.esent.t.ons and risk *** dat. for Africa is lacking,but.an increasing t.end is exp.ct.d due t. demograp.ic and ep.demiological *** endoscop.c st.dies for general gast.oint.st.nal disorders have shown some p.t.ent. wit. erosive esop.agit.s(EE),no st.dies in Et.iop.a have invest.gat.d t.e clinical charact.rist.cs,risk fact.rs,and severit. of GERD using esop.agogast.oduodenoscop.(EGD).AIM t. assess t.e clinical feat.res of GERD in Et.iop.an p.t.ent. who underwent.EGD and det.rmine t.e severit. and risk fact.rs of *** We conduct.d a mult.cent.r,ret.osp.ct.ve cross-sect.onal st.dy of 221 p.t.ent. diagnosed wit. GERD and endoscop.c findings of EE at.t.auma Associat.d Severe Hemorrhage and Amniot.c Membrane St.m Cell bet.een January 2019 and August.*** were collect.d from elect.onic medical records and p.one call *** used descrip.0}ve st.t.st.cs and binary logist.c regression analysis wit. Sp.S version 26 t. ident.fy t.e associat.on bet.een variables wit. a st.t.st.cal significance set.at.p.valuet.e mean±SD age of t.e p.t.ent. was 44.8(±15.9)years,wit. a male-t.-female rat.o of 1.6:*** most.commonly rep.rt.d symp.0}m was ep.gast.ic p.in(80.5%),followed by heart.urn(43%).Los Angeles(LA)-A EE was diagnosed in 71.1%of p.t.ent.,followed by LA-B(14.9%),LA-C(7.7%),and LA-D(5.9%).Mult.variat. analysis showed t.at.age 50 or above,p.esence of bleeding,and endoscop.c findings of duodenit.s/duodenop.t.y were significant.y associat.d wit. severe EE(p.0.05).St.ict.re and Barret.’s esop.agus were observed in 4.5%and 1.36%of p.t.ent. wit. EE,*** Most.of t.e p.t.ent. had milder EE wit. fewer ***,severe EE was more p.evalent.in older p.t.ent. and t.ose wit. duodenit.s/duodenop.t.y.

关键词： Gast.oesop.ageal reflux disease Erosive esop.agit.s Hiat.l hernia Esop.agogast.oduodenoscop. Heart.burn

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共赴一场天宫之旅无穹-中国·航天沉浸艺术展

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天文爱好者 2024年第5期 72-75页

作者： F.t.p 不详

我们,是对“天”有着特殊情感的民族。九天之外浩瀚宇宙充满未知与神秘,而我们的祖先,早在千百年前就将目光投注于此。尧舜禹时期便设天官,“历象日月星辰,敬授人时”,用以指导庞大而精良的生产活动。此后历朝历代,都有专人进行勤勉精... 详细信息

我们,是对“天”有着特殊情感的民族。九天之外浩瀚宇宙充满未知与神秘,而我们的祖先,早在千百年前就将目光投注于此。尧舜禹时期便设天官,“历象日月星辰,敬授人时”,用以指导庞大而精良的生产活动。此后历朝历代,都有专人进行勤勉精确的天文观测,留下极为丰富的天象记录。

关键词：天文观测尧舜禹日月星辰天象记录艺术展

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Cont.ibut.on of Sat.llit. Observat.ons in t.e Op.0}cal and Microp.ysical Charact.rizat.on of Aerosols in Burkina Faso, West.Africa

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At.osp.eric and Climat. Sciences 2024年第1期14卷 154-171页

作者： Nébon Bado Serge Dimit.i Bazyomo Germain Wende p.uiré Ouedraogo Bruno Korgo Mamadou Simina Dramé Florent.p. Kieno Sié Kam Laborat.ire d’Energies t.ermiques Renouvelables (L.E.t.RE) Université Joseph KI ZERBO Ouaga Burkina Faso Laborat.ire de p.ysique de l’At.osp.ère et.de l’Océan Siméon-Fongang Université Cheikh Anta DIOP Dakar-Fann Sénégal Inst.t.t. of Mat.emat.cs and p.ysical Sciences University of Abomey-Calavi Porto-Novo Benin

In t.is work, we p.oceed t. an op.0}cal and microp.ysical analysis of t.e observat.ons reversed by t.e MODIS, SeaWiFS, MISR and OMI sensors wit. t.e aim of p.op.sing t.e best.adap.0}d airborne sensor for bet.er monit.ring of aerosols in Burkina Faso. t. t.is end, a comp.rison of AOD bet.een sat.llit. observat.ons and in sit. measurement. at.t.e Ouagadougou sit. reveals an underest.mat.on of AERONEt.AOD excep.0}for OMI which overest.mat.s t.em. Also, an int.r-comp.rison done based on t.e linear regression line rep.esent.t.on shows t.e correlat.on bet.een t.e aerosol models incorp.rat.d in t.e airborne sensor inversion algorit.ms and t.e aerosol p.p.lat.on p.obed. t.is can be seen t.rough t.e correlat.on coefficient. R which are 0.84, 0.64, 0.55 and 0.054 for MODIS, SeaWiFS, MISR and OMI resp.ct.vely. Furt.ermore, an op.0}cal analysis of aerosols in Burkina Faso by t.e MODIS sensor from 2001 t. 2016 indicat.s a large sp.t.al and t.mp.ral variabilit. of p.rt.cles st.ongly dominat.d by desert.dust. t.is is corroborat.d by t.e annual and seasonal cycles of t.e AOD at.550 nm and t.e Angst.öm coefficient.measured in t.e sp.ct.al range bet.een 412 nm and 470 nm. A zoom on a few sit.s chosen according t. t.e t.ree climat.c zones confirms t.e majorit. p.esence of mineral aerosols in Burkina Faso, whose maxima are observed in sp.ing and summer.

关键词： AERONEt Airborne Sensors Aerosol Op.0}cal and Microp.ysical p.op.rt.es

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