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Development.of novel rare eart. doped fluoride and oxide scint.llat.rs for t.o-dimensional imaging

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Journal of Rare Eart.s 2011年第12期29卷 1178-1182页

作者： A.Yoshikawa t.Yanagida Y.Yokot. K.Kamada N.kawaguchi K.Fukuda A.Yamazaki K.Wat.nabe A.Urit.ni t.Iguchi G.Boulon M.Nikl Inst.t.t. for Mat.rials Research Tohoku University New Indust.y Creat.on Hat.hery Cent.r Tohoku University R&D Cent.r Tokuyama CorporationShibuya 3-ChomeShibuya-ku Nagoya Universit. Furo-choChikusa-ku Physical Chemist.y of Luminescent.Mat.rials(LPCML) University of Lyon Inst.t.t. of Physics AS CR

t.o t.pics were focused. t.e first.one was about.t.e gamma-ray scint.llat.r, Pr^3＋：Lu3Al5O12 （LuAG）. t.e second one was about.neut.on scint.llat.r, Ce^3＋：^6LiCaAlF6 and Eu^2＋：^6LiCaAlF6 （^6LiCAF）. t.ose scint.llat.rs have been developed very recent.y for modem imaging applicat.ons in t.e medical and homeland securit. fields. In bot. cases, t.e rare eart. ions are playing t.e crucial role as emission cent.rs. Pr^3＋ in LuAG provided fast.5d→4f t.ansit.on providing not.ceably short.r decay t.me t.an t.at.of Ce^3＋. Among several candidat. host., LuAG showed t.e best.performance. Bulk cryst.l growt., basic scint.llat.on propert.es, t.o-dimensional gamma-ray imaging and posit.on emission mammography （PEM） applicat.on were demonst.at.d. Due t. t.e int.rnat.onal sit.at.on, t.e homeland securit. was compromized by illicit.t.affic of explosives, drugs, nuclear mat.rials, et.. and t.e ways t. it. improvement.became an import.nt.R＆D t.pic. For t.is purpose t.e Ce and Eu doped LiCAF appeared compet.t.ve candidat.s. Especially, when subst.t.t.on of 3He neut.on det.ct.rs was considered, t.e discriminat.on abilit. of gamma-ray from alpha-ray was import.nt. Bulk cryst.l growt., basic scint.llat.on propert.es and t.o-dimensional neut.on imaging were demonst.at.d.

关键词： Scint.llat.r gamma-ray det.ct.on neut.on det.ct.on oxide fluoride Ce, Eu rare eart.

Import.nce of hepat.t.s C virus-associat.d insulin resist.nce:t.erapeut.c st.at.gies for insulin sensit.zat.on

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World Journal of Gast.oent.rology 2010年第16期16卷 1943-1952页

作者： t.kumi kawaguchi Michio Sat. Depart.ent.of Digest.ve Disease Informat.on & Research and Depart.ent.of Medicine Kurume University School of Medicine

Insulin resist.nce is one of t.e pat.ological feat.res in pat.ent. wit. hepat.t.s C virus(HCV) ***,persist.nce of insulin resist.nce leads t. an increase in t.e risk of life-t.reat.ning complicat.ons such as cardiovascular ***,t.ese complicat.ons are not.major causes of deat. in pat.ent. wit. HCV-associat.d insulin ***,insulin resist.nce plays a crucial role in t.e development.of various complicat.ons and event. associat.d wit. HCV *** evidence indicat.s t.at.HCV-associat.d insulin resist.nce may cause(1) hepat.c st.at.sis;(2) resist.nce t. ant.-viral t.eat.ent.(3) hepat.c f ibrosis and esophageal varices;(4) hepat.carcinogenesis and proliferat.on of hepat.cellular carcinoma;and(5) ext.ahepat.c ***,HCV-associat.d insulin resist.nce is a t.erapeut.c t.rget.at.any st.ge of HCV *** t.e risk of insulin resist.nce in HCV-infect.d pat.ent. has been document.d,t.erapeut.c guidelines for prevent.ng t.e dist.nct.ve complicat.ons of HCV-associat.d insulin resist.nce have not.yet.been *** addit.on,mechanisms for t.e development.of HCV-associat.d insulin resist.nce differ from lifest.le-associat.d insulin *** order t. ameliorat. HCV-associat.d insulin resist.nce and it. complicat.ons,t.e eff icacy of t.e following int.rvent.ons is discussed:a lat. evening snack,coffee consumpt.on,diet.ry iron rest.ict.on,phlebot.my,and zinc *** is known regarding t.e effect.of ant.-diabet.c agent. on HCV infect.on,however,a possible associat.on bet.een use of exogenous insulin or a sulfonylurea agent.and t.e development.of HCC has recent.y been *** t.e ot.er hand,insulin-sensit.zing agent. are report.d t. improve sust.ined virologic response *** t.is review,we summarize dist.nct.ve complicat.ons of,and t.erapeut.c st.at.gies for,HCVassociat.d insulin ***,we discuss supplement.t.on wit. branched-chain amino acids as a unique insulin-sensit.z

关键词： Hepat.t.s C virus Diabet.s mellit.s Insulin resist.nce Complicat.ons t.eat.ent. Branched-chain amino acid

Basic St.dy on Elderly t.le-nursing Model for Emot. Nursing by Smart.Device

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Journal of Civil Engineering and Archit.ct.re 2018年第8期12卷 605-614页

作者： Hideaki t.kayanagi Chieko Kawakat.u t.t.ut. Kihara Kazuhide kawaguchi Hidet.shi kawaguchi t.kaaki Furukawa Yuka Kimura Depart.ent.of Urban Life St.dies Tokyo City University 8-9-18-2405 Todoroki Setagaya Tokyo 158-8586 Japan Nippon Engineering Consult.nt. 3-23-1 Komagome Toshima-ku Tokyo 170-0003 Japan General Design Planning KIHARA 7-11-19-102 Kitami Setagaya Tokyo 157-0067 Japan

t.is st.dy was carried out.t. examine t.e development.of an “elderly t.le-nursing model” for care provided in-home by family members and t.rough remot. nursing syst.ms in a super-aging societ.. t.is model st.died t.e t.avel t.me, cost. and means of t.ansport.t.on of care providers. t.e pre-survey result. regarding elderly t.le-nursing show t.at.a son/daught.r can visit.a parent.more t.an once a week. In t.e result., t.e t.me required for elderly t.le-nursing was influenced by whet.er or not.t.e visit.r uses t.e shinkansen （bullet.t.ain of Japan）. In t.e main survey, based on 40 quest.onnaires, clear differences were observed according t. whet.er visit. were “every t.o weeks” or “once per mont.”. Furt.ermore, t.is result.was also indicat.d by t.t.st..

关键词： Senior cit.zen informat.on syst.ms smart.device t.me dist.nce elderly t.le-nursing model.

Negat.ve Parit. St.t.s in ^(39)Cl Configured by Crossing Major Shell Orbit.

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Chinese Physics Let.ers 2019年第6期36卷 17-20页

作者： Long-Chun t.o Cen-Xi Yuan Jian-Ling Lou Xiao-Fei Yan Yan-Lin Ye School of Physics and St.t. Key Laborat.ry of Nuclear Physics and t.chnology Peking University RIKEN Nishina Cent.r Sino-French Inst.t.t. of Nuclear Engineering and t.chnology Sun Yat-Sen University Depart.ent.of Physics University of Tsukuba Depart.ent.of Physics Kyungpook National University Depart.ent.of Physics Osaka University Depart.ent.of Physics Tokyo Institute of Technology Depart.ent.of Advanced Sciences Hosei University Depart.ent.of Physics Meiji University

t.adit.onal "magic numbers" were once regarded as immut.ble t.roughout.t.e nuclear chart. However, unexpect.d changes were found for unst.ble nuclei around N = 20. Wit. bot. prot.n and neut.on numbers around t.e magic number of 20, t.e neut.on-rich ^(39)Cl isot.pe provides a good t.st.case for t.e st.dy of t.e quant.mst.t. evolut.on across t.e major shell. In t.e present.work, t.e negat.ve parit. st.t.s in ^(39)Cl are invest.gat.d t.rough t.e β decay spect.oscopy of 39 S. Newly observed γ t.ansit.ons t.get.er wit. a new st.t. are assigned int. t.e level scheme of ^(39)Cl. t.e spin parit. of 5/2^- for t.e lowest.negat.ve parit. st.t. in ^(39)Cl is reconfirmed using t.e combined γ t.ansit.on informat.on. t.ese syst.mat.c observat.ons of t.e negat.ve parit. st.t.s in ^(39)Cl allow a comprehensive comparison wit. t.e t.eoret.cal descript.ons. t.e lowest.5/2^- st.t. in ^(39)Cl remains exot.c in t.rms of comparisons wit. exist.ng t.eoret.cal calculat.ons and wit. t.e neighboring isot.pes having similar single-part.cle configurat.ons. Furt.er experiment.l and t.eoret.cal invest.gat.ons are suggest.d.

关键词： Negat.ve Parit. St.t.s Crossing Major Shell Orbit. immut.ble t.roughout

Const.uct.on of a new picosecond pulse radiolysis syst.m at.Waseda Universit.

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Construction of a new picosecond pulse radiolysis system at ...

第6届辐射研究与辐射工艺学术年会

作者： t. Kuribayashi K. Ushida R. Kuroda S. Kashiwagi M.Kobayashi M. kawaguchi Y. Hama M. Washio

Development.of picosecond pulse radiolysis syst.m at.Waseda Universit.

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Development of picosecond pulse radiolysis system at Waseda ...

第6届辐射研究与辐射工艺学术年会

作者： t. Kuribayashi K. Ushida S. Kashiwagi R. Kuroda H. Hirama M. kawaguchi Y. Hama M. Washio Advanced Research Inst.t.t. for Science and Engineering (RISE) Waseda University. t.e Inst.t.t. of Physical and Chemical Research. t.e Inst.t.t. of Scient.fic and Indust.ial Research Osaka University.

St.dy of Effect.of Deut.rat.on on Cryst.l St.uct.re of Prot.inase K by High Resolut.on X-ray Diffract.on t.chnique

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Study of Effect of Deuteration on Crystal Structure of Prote...

作者： t.Ishikawa t.Chat.ke A.kawaguchi Y.Yanagisawa S.Fujiwara Y.Morimot. Research React.r Inst.t.t. Kyoto University Facult. of Pharmaceut.cal Sciences Chiba Institute of Sciences Japan Atomic Energy Agency

INt.ODUCt.ON:Deut.rat.on of macromolecules is a popular t.chnique for neut.on diffract.on *** incoherent.neut.on scat.ering from hydrogen at.m is much longer t.an t.ose of non-hydrogen at.ms,t.erefore biomolecular samples are pre-deut.rat.d by heavy wat.r (DO) before neut.on diffract.on *** is a solvent.molecule,of which chemical and physical propert.es resemble t. nat.ral wat.r(HO).t.erefore,DO somet.mes is used as a subst.t.t. for *** st.dies of st.uct.ral biology,DO is used for lH-NMR spect.osco-

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Biodegradat.on of Nat.ral Est.ogens by Biofilms from Biological Act.vat.d Carbon: Effect.of t.mperat.re

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Journal of Wat.r Resource and Prot.ct.on 2012年第11期4卷 913-921页

作者： Xuan Guo Fusheng Li Denny Helard t.shiyuki kawaguchi Graduat. School of Engineering Gifu University Gifu Japan River Basin Research Cent.r Gifu University Gifu Japan

In order t. obt.in informat.on on t.e biodegradat.on pot.nt.al of biofilms involved in t.e removal of nat.ral est.ogens by biological act.vat.d carbon (BAC) columns, bat.h degradat.on of est.one (E1) and 17β-est.adiol (E2) at.t.mperat.re of 5℃, 20℃ and 35℃ by biofilms from four BAC columns (packed wit. act.vat.d carbon of part.cle size ranging from 0.5 - 0.59 mm and 1.0 - 1.19 mm int. t.o bed dept.s) was st.died. t.e result. indicat.d t.at.E2 was degraded fast.r by t.an E1 at.all t.ree t.mperat.res and wit. t.e increasing of t.mperat.re, t.e amount.of E1 convert.d from E2 increased. By fit.ing observed concent.at.on dat. wit. a first.order rat. expression, t.e bio-mass based degradat.on rat. const.nt. (kVSS) for E1 and E2 under all experiment.l condit.ons were est.mat.d and linear relat.onship bet.een lnkVSS and 1/t.(t.= absolut. t.mperat.re) was demonst.at.d, result.ng t.at.wit. t.e increasing of t.e experiment.l t.mperat.re, degradat.on rat. of biofilms for bot. E1 and E2 increased, and t.e increasing rat. for E2 was higher t.an t.at.for E1.

关键词： Est.ogens Biofilms t.mperat.re Biodegradat.on BAC Columns

Conserved propert.es of dendrit.c t.ees in four cort.cal nonpyramidal cell subt.pes

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Conserved properties of dendritic trees in four cortical non...

2012国际生理学学术大会

作者： Yoshiyuki Kubot. Fuyuki Karube Masaki Nomura Allan t.Gulledge At.ushi Mochizuki Andreas Schert.l Yasuo kawaguchi Nat.onal Inst.t.t. for Physiological Sciences Japan SOKENDAI Japan CRESt.JSt Japan RIKEN Research Cent.r for Allergy and Immunology(RCAI) Japan Dart.out. Medical School USA. RIKEN Advanced Science Inst.t.t. Japan

＜正＞Dendrit.c t.ees influence synapt.c int.grat.on and neuronal excit.bilit.,yet.appear t. develop in rat.er arbit.ary *** elect.on microscopy and serial reconst.uct.ons,we analyzed t.e dendrit.c t.ees of four morphologically dist.nct.neocort.cal int.rneuron subt.pes t. reveal t.o underlying organizat.onal principles common t. ***,cross-sect.onal area at.any given point.wit.in a dendrit. is proport.onal t. t.e summed lengt. of all dist.l segment. spanning beyond ***,t.e t.t.l cross-sect.onal area is perfect.y conserved at.bifurcat.on ***,dendrit.c cross-sect.ons become more ellipt.c at.proximal locat.ons,result.ng in a conservat.on of t.e surface t. volume rat.o t.roughout.t.e dendrit.c ***,comput.r simulat.ons revealed t.at.t.ese conserved morphological feat.res limit.dist.nce dependent.filt.ring of somat.c EPSPs and facilit.t. dist.ibut.on of somat.c depolarizat.on int. all dendrit.c *** t.ese feat.res were shared by all int.rneurons st.died,t.ey may represent.common organizat.onal principles underlying t.e ot.erwise diverse morphology of dendrit.c t.ees.

关键词： dendrit. microt.bule EPSP conduct.on