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t.nnel silicon nit.ide manipulat.d reconf.gurable bi-mode nocicept.r analog

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Phot.nics Research 2024年第8期12卷 1820-1827页

作者： CHENGDONG YANG YILONG LIU LINLIN su XINWEI LI LIHUA XU QIMEI CHENG Jiangsu Province Engineering Research Cent.r of.Int.grat.d Circuit.Reliabilit. t.chnology and t.st.ng Syst.m Wuxi UniversityWuxi 214105China

Neuromorphic applicat.ons have shown great.promise not.only f.r ef.icient.parallel comput.ng mode t. hold cert.in comput.t.onal t.sks,such as percept.on and recognit.on,but.also as key biomimet.c element. f.r t. int.lligent.sensory syst.m of.next.generat.on ***,achieving such a biomimet.c nocicept.r t.a can adapt.vely swit.h operat.on mode wit. a st.mulat.on t.reshold remains a *** rat.onal design of.mat.rial propert.es and device st.uct.res,we realized an easily-f.bricat.d,low-energy,and reconf.gurable no *** is capable of.t.reshold-t.iggered adapt.ve bi-mode jump t.at.resembles t.e biological alarm syst.m Wit. a t.nnel silicon nit.ide(Si_(3)N_(4))we mimicked t.e int.nsit.-and rehearsal-t.iggered jump by means of.t. t.nneling mode t.ansit.on of.Si_(3)N_(4)*** t.reshold signals t.e device can also express some common synapt.c f.nct.ons wit. an ext.emely low energy densit. of.33.5 f.J∕μm^(2).In addit.on,t.rough t.e modulat.on o Si_(3)N_(4)t.ickness it.is relat.vely easy t. f.bricat. t.e device wit. dif.ering pain *** nocicept.r analog based on a t.nneling layer provides an opport.nit. f.r t.e analog pain alarm syst.m and opens up a new pat. t.ward t.reshold-relat.d novel applicat.ons.

关键词： t.nnel t.nneling rat.onal

t.eoret.cal underst.nding of.correlat.on bet.een magnet.c phase t.ansit.on and t.e superconduct.ng dome in high-t. cuprat.s

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Science China(Physics,Mechanics & Ast.onomy) 2024年第2期67卷 167-173页

作者： Chen Zhang Cai-Xin Zhang su-Huai Wei Haiqing Lin Hui-Xiong Deng St.t. Key Laborat.ry of.superlat.ices and Microst.uct.res Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Cent.r of.Mat.rials Science and Opt.elect.onics Engineering University of Chinese Academy of SciencesBeijing 100049China Beijing Comput.t.onal Science Research Cent.r Beijing 100193China

Many issues concerning t.e origin of.high-t.mperat.re superconduct.vit.(Ht.)are st.ll under *** example,how t.e magnet.c order varies wit. doping and it. relat.onship wit. t.e superconduct.ng t.mperat.re(t.);and why t.always peaks near t.e quant.m crit.cal *** t.is paper,t.king hole-doped La_(2)CuO_(4)as a classical example,we employ t.e f.rst.principles band st.uct.re and t.t.l energy calculat.ons wit. Mont. Carlo simulat.ons t. explore how t.e symmet.y-breaking magnet.c ground st.t. evolves wit. hole doping and t.e origin of.a dome-shaped superconduct.vit. region in t.e phase *** demonst.at. t.at.t.e local ant.f.rromagnet.c order and doping play key roles in det.rmining t.e elect.on-phonon coupling,t.us ***,t.e La_(2)CuO_(4)possesses a checkerboard local ant.f.rromagnet.c ground *** t.e hole doping increases,t.increases wit. t.e enhanced elect.on-phonon coupling *** as t.e doping increases f.rt.er,t.e st.engt. of.t.e ant.f.rromagnet.c int.ract.on weakens and spin f.uct.at.on *** t.e crit.cal doping level,a magnet.c phase t.ansit.on occurs t.at.reduces t.e local ant.f.rromagnet.sm-assist.d elect.on-phonon coupling,t.us diminishing t.e *** superconduct.vit. disappears in t.e heavily overdoped region when t.e f.rromagnet.c order *** observat.ons could account.f.r why cuprat.s have a dome-shaped superconduct.vit. region in t.e phase *** st.dy,t.us,cont.ibut.s t. a f.ndament.l underst.nding of.t.e correlat.on bet.een doping,local magnet.c order,and superconduct.vit. of.Ht..

关键词： high-t.mperat.re superconduct.vit. ant.f.rromagnet.c order elect.on-phonon coupling doping ef.ect cuprat.s

Mapk7 delet.on in chondrocyt.s causes vert.bral def.ct. by reducing MEf.C/Pt.N/AKt.signaling

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Genes & Diseases 2024年第2期11卷 964-977页

作者： Chengzhi Wu Hengyu Liu Dongmei Zhong Xiaoming Yang Zhiheng Liao Yuyu Chen Shun Zhang Deying su Baolin Zhang Chuan Li Liru t.an Caixia Xu Peiqiang su Guangdong Provincial Key Laborat.ry of.Ort.opedics and t.aumat.logy Department of Spine SurgeryThe First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510080China Research Cent.r f.r t.anslat.onal Medicine The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510080China Precision Medicine Inst.t.t. The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510080China Depart.ent.of.Ort.opedics Renmin Hospital of Wuhan UniversityWuhanHubei 430060China Guangdong Provincial Key Laborat.ry of.Prot.omics and St.t. Key Laborat.ry of.Organ f.ilure Research School of Basic Medical SciencesSouthern Medical UniversityGuangzhouGuangdong 510515China

Mut.t.on of.t.e MAPK7 gene was relat.d t. human ***7 regulat.d t.e development.of.limb bones and skulls in ***,t.e role of.MAPK7 in vert.bral development.is st.ll *** t.is st.dy,we const.uct.d Col2a1-cre;Mapk7 f.f.t.ansgenic mouse model t. delet. Mapk7 in cart.lage,which displayed kyphosis and ***,Mapk7 loss decreased MEf.C expression and t.us act.vat.d Pt.N t. oppose PI3K/AKt.signaling in vert.bral growt. plat. chondrocyt.s,which impaired chondrocyt. hypert.ophy and at.enuat.d vert.bral *** vivo,syst.mic pharmacological act.vat.on of.AKt.rescued impaired chondrocyt. hypert.ophy and alleviat.d mouse vert.bral def.ct. caused by Mapk7 *** st.dy f.rst.y clarif.ed t.e mechanism by which MAPK7 was involved in vert.bral development.which might.cont.ibut. t. underst.nding t.e pat.ology of.spinal def.rmit. and provide a basis f.r t.e t.eat.ent.of.development.l disorders of.t.e spine.

关键词： Chondrocyt. hypert.ophy Growt. plat. Kyphosis MAPK7 MEf.C Ost.openia PI3K/AKt Pt.N

t.ssue dist.ibut.on of.cadmium and it. ef.ect.on reproduct.on in Spodopt.ra exigua

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Journal of.Int.grat.ve Agricult.re 2024年第1期23卷 195-204页

作者： Honghua su Menglu Wu Yong Yang Yan Deng Yizhong Yang Qingming sun College of.Plant.Prot.ct.on Yangzhou UniversityYangzhou 225009China Inst.t.t. of.f.uit.t.ee Research Guangdong Academy of Agricultural Sciences/Key Laboratory of South Subtropical Fruit Biology and Genetic Resource UtilizationMinistry of Agriculture and Rural Affairs/Guangdong Provincial Key Laboratory of Tropical and Subtropical Fruit Tree ResearchGuangzhou 510640China

Veget.ble f.elds are of.0}n cont.minat.d by heavy met.ls,and Spodopt.ra exigua is a major veget.ble pest.which is st.essed by heavy met.ls mainly by *** t.is st.dy,cadmium accumulat.on in t.e t.ssues of.*** exposed t. cadmium and it. ef.ect. on t.e growt. and development.of.t.e parent. and t.e of.spring were *** t.e st.ess of.dif.erent.concent.at.ons of.cadmium(0.2,3.2,and 51.2 mg kg^(-1)),t.e cadmium cont.nt.in each t.ssue of.*** increased in a dose-dependent.*** t.e larval st.ge,t.e highest.cadmium accumulat.on was f.und in midgut.in all t.ree cadmium t.eat.ent.,but.at.t.e adult.st.ge,t.e highest.cadmium cont.nt.was f.und in f.t.*** addit.on,t.e cadmium cont.nt.in ovaries was much higher t.an in *** *** was st.essed by cadmium and t.e f.(2)generat.on was not.f.d a cadmium-cont.ining diet.t.e larval survival,pupat.on rat.,emergence rat. and f.cundit. of.t.e f.(2)generat.on were signif.cant.y reduced in t.e 51.2 mg kg^(-1)t.eat.ent.compared t. t.e corresponding *** in t.e f.(2)generat.on of.t.e 3.2 mg kg^(-1)t.eat.ent.t.e f.cundit. was signif.cant.y lower t.an in t.e parent.l *** f.cundit. of.t.e only-f.male st.essed t.eat.ent.was signif.cant.y lower t.an t.at.of.t.e only-male st.essed t.eat.ent.at.t.e 3.2 and 51.2 mg kg^(-1)cadmium exposure *** only mot.ers were st.essed at.t.e larval st.ge,t.e f.cundit. of.t.e f.(2)generat.on was signif.cant.y lower t.an t.at.of.t.e f.generat.on in t.e 51.2 mg kg^(-1)t.eat.ent.and it.was also signif.cant.y lower t.an in t.e 3.2 and 0.2 mg kg^(-1)*** result. of.our st.dy can provide usef.l inf.rmat.on f.r f.recast.ng t.e populat.on increase t.ends under dif.erent.heavy met.l st.ess condit.ons and f.r t.e reliable environment.l risk assessment.of.heavy met.l pollut.on.

关键词： heavy met.l pollut.on cadmium Spodopt.ra exigua t.ssue dist.ibut.on reproduct.on

f.bricat.ng f.nct.onally graded f.-Cr-Co permanent.magnet.c alloys via laser powder bed f.sion

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Journal of.Iron and St.el Research Int.rnat.onal 2024年第3期31卷 729-737页

作者： Ya-zhou He Ya-qing Hou Peng Shen Hao Zhang Dong Zhou Hang su Cent.al Iron and St.el Research Inst.t.t. Co. Ltd.Beijing 100081China Mat.rial Digit.l R&D Cent.r China Iron and Steel Research Institute Group Co.Ltd.Beijing 100081China

Laser powder bed f.sion(LPBf.in-sit. alloying t.chnology of.ers t.e possibilit. t. const.uct.gradient.mat.rials wit. varied st.uct.res and *** graded f.-Cr-Co permanent.magnet.c alloys were f.bricat.d by LPBf.and in-sit. alloying mixed powders of.f.,Cr,and Co *** ef.ect. of.dif.erent.f.,Cr and Co cont.nt. on t.e microst.uct.re,magnet.c propert.es and hardness of.f.-Cr-Co alloys prepared by LPBf.were *** as-built.f.-Cr-Co alloys present.a single body-cent.red-cubic phase and have a homogeneous dist.ibut.on of.*** mechanical propert.es and magnet.c propert.es of.t.e composit.onally graded sample show a gradient.*** t.e increase in Cr cont.nt.t.e Vickers hardness of.t.e sample increases,and t.e sat.rat.on magnet.zat.on of.t.e sample *** opt.mal magnet.c propert.es in an isot.opic st.t. are given as coercivit. HcB=21.65 kA/m,remanence Br=0.70 t.and energy product.BH)_(max)=5.35 kJ/m^(3),which are comparable t. or higher t.an t.e report.d magnet.c propert.es in an isot.opic st.t. prepared by t.adit.onal powder *** in-sit. alloying t.chnology has t.e pot.nt.al t. f.rt.er explore f.-Cr-Co magnet.c mat.rials,such as t.ose consist.ng of.mult.ple or more const.t.ent.element.,and t. maximize t.e composit.onal f.exibilit. of.magnet.c mat.rials.

关键词： f.-Cr-Co alloy Laser powder bed f.sion In-sit. alloying f.nct.onal mat.rial Magnet.c propert.

Mult.ple conduct.ve net.ork f.r Kt._(2)(PO_(4))_(3)anode based on MXene as a binder f.r high-perf.rmance pot.ssium st.rage

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Chinese Chemical Let.ers 2024年第8期35卷 539-544页

作者： t.ng su Yue Wang Qizhen Zhu Mengyao Xu Ning Qiao Bin Xu St.t. Key Laborat.ry of.Organic-Inorganic Composit.s Beijing Key Laboratory of Electrochemical Process and Technology for MaterialsBeijing University of Chemical TechnologyBeijing 100029China

Kt._(2)(PO_(4))_(3)is a promising anode mat.rial f.r pot.ssium st.rage,but.suf.ers f.om low conduct.vit. and dif.icult.balance bet.een high capacit. and good st.uct.ral ***,t.e t._(3)C_(2)t.(x)MXene is used as a mult.f.nct.onal binder t. f.bricat. t.e Kt._(2)(PO_(4))_(3)elect.ode by t.e t.adit.onal homogenizing-coat.ng *** MXene nanosheet.,t.get.er wit. t.e conduct.ve agent.super P nanopart.cles,const.uct.a mult.ple conduct.ve net.ork f.r f.st.elect.on/ion t.ansf.r and high elect.ochemical ***,t.e net.ork ensures t.e st.uct.ral st.bilit. of.t.e Kt._(2)(PO_(4))_(3)elect.ode during t.e de-int.rcalat.on/int.rcalat.on of.4 K^(+)ions,which is benef.cial f.r simult.neously achieving high capacit. and good cycle ***,t.e MXene-bonded Kt._(2)(PO_(4))_(3)elect.ode delivers a reversible capacit. of.255.2 mAh/g at.50 mA/g,out.t.nding rat. capabilit. wit. 132.3 mAh/g at.2 A/g,and ex-cellent.cycle perf.rmance wit. 151.6 mAh/g at.1 A/g af.0}r 2000 *** work not.only suggest. a high-perf.rmance anode mat.rial f.r pot.ssium-ion bat.eries,but.also demonst.at.s t.at.t.e MXene is a promising binder mat.rial f.r const.uct.ng conduct.ve elect.odes in rechargeable bat.eries.

关键词： MXene t._(3)C_(2)t.(x) Kt._(2)(PO_(4))_(3) Anode Conduct.ve net.ork Pot.ssium st.rage

Evolut.on of.nonmet.llic inclusions in 80-t.9CrMoCoB large-scale ingot. during elect.oslag remelt.ng process

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Int.rnat.onal Journal of.Minerals,Met.llurgy and Mat.rials 2024年第7期31卷 1525-1539页

作者： Shengchao Duan Min Joo Lee Yao su Wangzhong Mu Dong Soo Kim Joo Hyun Park School of.Mechanical and Mat.rials Engineering North China University of TechnologyBeijing 100144China Depart.ent.of.Mat.rials Science and Chemical Engineering Hanyang UniversityAnsan 15588Rep.of Korea Depart.ent.of.Mat.rials Science and Engineering KTH Royal Institute of TechnologyBrinellvägen 23Stockholm 10044Sweden Depart.ent.of.Engineering Science and Mat.emat.cs Division of Materials ScienceLuleåUniversity of Technology97187 LuleåSweden Cast.ng&f.rging Business Unit Nuclear Business GroupDoosan EnerbilityChangwon 51711Rep.of Korea

In combinat.on wit. t.eoret.cal calculat.ons,experiment. were conduct.d t. invest.gat. t.e evolut.on behavior of.nonmet.llic inclusions(NMIs)during t.e manuf.ct.re of.large-scale heat.resist.nt.st.el ingot. using 9CrMoCoB heat.resist.nt.st.el and Caf.(2)–CaO–Al_(2)O_(3)–SiO_(2)–B_(2)O_(3)elect.oslag remelt.ng(ESR)-t.pe slag in an 80-t.indust.ial ESR *** main t.pes of.NMI in t.e consumable elect.ode comprised pure alumina,a mult.phase oxide consist.ng of.an Al_(2)O_(3)core and liquid CaO–Al_(2)O_(3)–SiO_(2)–MnO shell,and M_(23)C_(6)carbides wit. an MnS *** Al_(2)O_(3)and MnS inclusions had higher precipit.t.on t.mperat.res t.an t.e M_(23)C_(6)-t.pe carbide under equilibrium and nonequilibrium solidif.cat.on ***,inclusions can act.as nucleat.on sit.s f.r carbide layer *** ESR process complet.ly removed t.e liquid CaO–Al_(2)O_(3)–SiO_(2)–MnO oxide and MnS inclusion wit. a carbide shell,and only t.e Al_(2)O_(3)inclusions and Al_(2)O_(3)core wit. a carbide shell occupied t.e remelt.d *** M_(23)C_(6)-t.pe carbides in st.el were det.rmined as Cr_(23)C_(6)based on t.e analysis of.t.ansmission elect.on microscopy *** subst.t.t.on of.Cr wit. W,f.,or/and Mo in t.e Cr_(23)C_(6)lat.ice caused slight.changes in t.e lat.ice paramet.r of.t.e Cr_(23)C_(6)***,Cr_(21.34)f._(1.66)C_(6),(Cr_(19)W_(4)C_(6),Cr_(18.4)Mo_(4.6)C_(6),and Cr_(16)f._(5)Mo_(2)C_(6)can mat.h t.e f.act.on pat.ern of.Cr_(23)C_(6)*** Al_(2)O_(3)inclusions in t.e remelt.d ingot.f.rmed due t. t.e reduct.on of.CaO,SiO_(2),and MnO component. in t.e liquid *** increased Al cont.nt.in liquid st.el or t.e higher supersat.rat.on degree of.Al_(2)O_(3)precipit.t.on in t.e remelt.d ingot.t.an t.at.in t.e elect.ode can be at.ribut.d t. t.e evaporat.on of.Caf.(2)and t.e increase in CaO cont.nt.in t.e ESR-t.pe slag.

关键词： nonmet.llic inclusion heat.resist.nt.st.el elect.oslag remelt.ng M_(23)C_(6) carbide MnS inclusion supersat.rat.on degree

In-sit. const.uct.on of.grass-like hybrid archit.ct.re responsible f.r ext.aordinary corrosion perf.rmance: Experiment.l and t.eoret.cal approach

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Nano Mat.rials Science 2024年第1期6卷 44-59页

作者： t.suhart.no f.Hazmat.lhaq Y.Sheng A.Chaouiki M.P.Kamil Y.G.Ko Mat.rials Elect.ochemist.y Group School of Materials Science and EngineeringYeungnam UniversityGyeongsan38541Republic of Korea Research Cent.r f.r Advanced Mat.rials National Research and Innovation Agency(BRIN)South TangerangBanten15314Indonesia

Despit. t.e engineering pot.nt.al by t.e co-exist.nce of.inorganic and organic subst.nces t. prot.ct.vulnerable met.llic mat.rials f.om corrosive environment.,bot. t.eir int.ract.on and in-sit. f.rmat.on mechanism t. induce t.e nat.re-inspired composit. remained less *** present.work used t.ree dist.nct.ve mercapt.benzazole(MB)compounds working as corrosion inhibit.rs,such as 2-mercapt.benzoxazole(MBO),2-mercapt.benzot.iazole(MBt.,and 2-mercapt.benzimidazole(MBI)in a bid t. underst.nd how t.e geomet.ical st.uct.re arising f.om O,S,and N at.ms af.ect.d t.e int.ract.on t.ward inorganic *** compounds t.at.were used here t. cont.ol t.e corrosion kinet.cs would be int.ract.d readily wit. t.e pre-exist.ng MgO layer f.bricat.d by plasma *** phenomenon t.iggered t.e nucleat.on of.t.e root.net.ork since MB compounds were seen t. be adsorbed act.vely on t.e def.ct.ve surf.ce t.rough t.e act.ve sit.s in MB ***,t.e molecule wit. t.in donor at.ms adjacent.t. t.e mercapt.-sit.s af.ect.d t.e f.cile growt. of.t.e grass-like st.uct.res wit.‘unif.rm’dist.ibut.on via molecular self.assembly,which showed bet.er corrosion perf.rmance t.an t.ose wit. having dissimilar donor at.ms wit. t.e inhibit.on ef.iciency(η)of.97%*** f.rmat.on mechanism underlying nucleat.on and growt. behavior of.MB molecule was discussed concerning t.e t.eoret.cal calculat.on of.densit. f.nct.onal t.eory.

关键词： Nat.re-inspired composit. Organic-inorganic int.ract.on Corrosion inhibit.r Densit. f.nct.onal t.eory Elect.ochemist.y

Benchmarking Algorit.ms f.r Gene Set.Scoring of.Single-cell At.C-seq Dat.

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Genomics, Prot.omics & Bioinf.rmat.cs 2024年第2期22卷 27-42页

作者： Xi Wang Qiwei Lian Haoyu Dong Shuo Xu Yaru su Xiaohui Wu Past.urien College Suzhou Medical College of Soochow UniversitySoochow UniversitySuzhou 215000China Depart.ent.of.Aut.mat.on Xiamen UniversityXiamen 361005China College of.Mat.emat.cs and Comput.r Science Fuzhou UniversityFuzhou 350116China

Gene set.scoring(GSS)has been rout.nely conduct.d f.r gene expression analysis of.bulk or single-cell RNA sequencing(RNA-seq)dat.,which helps t. decipher single-cell het.rogeneit. and cell t.pe-specif.c variabilit. by incorporat.ng prior knowledge f.om f.nct.onal gene ***-cell assay f.r t.ansposase accessible chromat.n using sequencing(scAt.C-seq)is a powerf.l t.chnique f.r int.rrogat.ng single-cell chromat.n-based gene regulat.on,and genes or gene set. wit. dynamic regulat.ry pot.nt.als can be regarded as cell t.pe-specif.c markers as if.in single-cell RNA-seq(scRNA-seq).However,t.ere are f.w GSS t.ols specif.cally designed f.r scAt.C-seq,and t.e applicabilit. and perf.rmance of.RNA-seq GSS t.ols on scAt.C-seq dat. remain t. be ***,we syst.mat.cally benchmarked t.n GSS t.ols,including f.ur bulk RNA-seq t.ols,f.ve scRNA-seq t.ols,and one scAt.C-seq ***,using mat.hed scAt.C-seq and scRNA-seq dat.set.,we f.und t.at.t.e perf.rmance of.GSS t.ols on scAt.C-seq dat. was comparable t. t.at.on scRNA-seq,suggest.ng t.eir applicabilit. t. ***,t.e perf.rmance of.dif.erent.GSS t.ols was ext.nsively evaluat.d using up t. t.n scAt.C-seq ***,we evaluat.d t.e impact.of.gene act.vit. conversion,dropout.imput.t.on,and gene set.collect.ons on t.e result. of.*** show t.at.dropout.imput.t.on can signif.cant.y promot. t.e perf.rmance of.almost.all GSS t.ols,while t.e impact.of.gene act.vit. conversion met.ods or gene set.collect.ons on GSS perf.rmance is more dependent.on GSS t.ols or ***,we provided pract.cal guidelines f.r choosing appropriat. preprocessing met.ods and GSS t.ols in dif.erent.applicat.on scenarios.

关键词： Single-cell At.C-seq Gene set.scoring Pat.way analysis Single-cell RNA-seq Benchmark