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t.anscript.mic and machine learning analyses ident.f. hub genes of.met.bolism and host.immune response t.at.are associat.d wit. t.e progression of.breast.capsular cont.act.re

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Genes & Diseases 2024年第3期11卷 427-437页

作者： Yukun Mao Xueying Hou su f. Jie Luan Breast.Plast.c and Reconst.uct.ve surgery Cent.r Plastic Surgery HospitalChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100144China

Capsular cont.act.re is a prevalent.and severe complicat.on t.at.af.ect. t.e post.operat.ve out.omes of.pat.ent. who receive silicone breast.*** present.prost.esis replacement.is t.e major t.eat.ent.f.r capsular cont.act.re af.0}r bot. breast.augment.t.on procedures and breast.reconst.uct.on f.llowing breast.cancer ***,t.e mecha-nism(s)underlying breast.capsular cont.act.re remains *** st.dy aimed t. ident.f. t.e biological f.at.res of.breast.capsular cont.act.re and reveal t.e pot.nt.al underlying mechanism using RNA *** t.ssues f.om 12 f.male pat.ent.(15 breast.capsules)were divided int. low capsular cont.act.re(LCC)and high capsular cont.act.re(HCC)groups based on t.e Baker ***,41 lipid met.bolism-relat.d genes were ident.f.ed t.rough enrichment.analysis,and t.ree of.t.ese genes were ident.f.ed as candidat. genes by SVM-Rf. and LASSO *** t.en compared t.e proport.ons of.t.e 22 t.pes of.im-mune cells bet.een t.e LCC and HCC groups using a CIBERSORt.analysis and explored t.e Cor-relat.on bet.een t.e candidat. hub f.at.res and immune ***,PRKAR2B was posit.vely correlat.d wit. t.e dif.erent.ally clust.red immune cells,which were M1 macro-phages and f.llicular helper t.cells(area under t.e ROC=0.786).In addit.on,t.e expression of.PRKAR2B at.t.e mRNA or prot.in level was lower in t.e HCC group t.an in t.e LCC *** molecular mechanisms were ident.f.ed based on t.e expression levels in t.e high and low PRKAR2B *** f.ndings indicat. t.at.PRKAR2B is a novel diagnost.c biomarker f.r breast.capsular cont.act.re and might.also inf.uence t.e grade and progression of.capsularcont.act.re.

关键词： Biomarker Breast.apsular cont.act.re Immune inf.lt.at.on Machinelearning algorit.ms PRKAR2B

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A versat.le model wit. t.ree-dimensional t.iangular lat.ice f.r unconvent.onal t.ansport.and various t.pological ef.ect.

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Nat.onal Science Review 2024年第1期11卷 204-214页

作者： Jing-Yang You Gang su Yuan Ping f.ng Depart.ent.of.Physics National University of Singapore Kavli Inst.t.t. f.r t.eoret.cal Sciences and CAS Center for Excellence in Topological Quantum Computation University of Chinese Academy of Sciences Cent.e f.r Advanced 2D Mat.rials National University of Singapore

t.e f.nit. Berry curvat.re in t.pological mat.rials can induce many subt.e phenomena, such as t.e anomalous Hall ef.ect.AHE), spin Hall ef.ect.SHE), anomalous Nernst.ef.ect.ANE), non-linear Hall ef.ect.NLHE) and bulk phot.volt.ic ef.ect.. t. explore t.ese novel physics as well as t.eir connect.on and coupling, a precise and ef.ect.ve model should be developed. Here, we propose such a versat.le model—a 3D t.iangular lat.ice wit. alt.rnat.ng hopping paramet.rs, which can yield various t.pological phases,including kagome bands, t.iply degenerat. f.rmions, double Weyl semimet.ls and so on. We reveal t.at.t.is special lat.ice can present.unconvent.onal t.ansport.due t. it. unique t.pological surf.ce st.t.s and t.e af.rement.oned t.pological phenomena, such as AHE, ANE, NLHE and t.e t.pological phot.current.ef.ect. In addit.on, we also provide a number of.mat.rial candidat.s t.at.have been synt.esized experiment.lly wit. t.is lat.ice, and discuss t.o mat.rials, including a non-magnet.c t.iangular syst.m f.r SHE, NLHE and t.e shif.0}current. and a f.rromagnet.c t.iangular lat.ice f.r AHE and ANE. Our work provides an excellent.plat.orm, including bot. t.e model and mat.rials, f.r t.e st.dy of.Berry-curvat.re-relat.d physics.

关键词： t.ree-dimensional t.iangular lat.ice dif.erent.t.pological phases various t.pological ef.ect. Berry curvat.re

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surf.ct.nt.assist.d cryst.llizat.on of.lysozyme and it. mechanism

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Part.cuology 2024年第7期90卷 199-208页

作者： Yujie Song Rongf.i Ren Min su Zhihan Liang Qi Hao School of.Chemical Engineering Hebei University of TechnologyTianjin 300130China

surf.ct.nt. were used t. assist.in t.e cryst.llizat.on of.*** t.pes of.surf.ct.nt. wit. dif.erent.st.uct.res(sodium dodecyl sulf.t.,cet.lt.imet.ylammonium bromide,or bet.ine hydrochloride[BH])were *** st.dy indicat.d t.at.t.ree surf.ct.nt. were all capable of.short.ning t.e cryst.llizat.on induct.on t.me of.lysozyme,wit. BH inducing t.e short.st.cryst.llizat.on induct.on t.me(t.1 min)and t.e largest.cryst.l size(37μm).t.e molecular int.ract.ons among each of.t.e t.ree surf.ct.nt. af.rement.oned and lysozyme were also invest.gat.d by *** was f.und t.at.hydrogen bonding dominant.y act.d bet.een t.e carboxyl st.uct.re of.t.e surf.ct.nt.BH and t.e lysozyme,which produced t.e most.f.vorable conf.rmat.on f.r t.e self.assembly of.lysozyme(promot. lysozyme orderly aggregat.on and short.n t.e cryst.llizat.on induct.on t.me).On t.is basis,t.e mechanism of.surf.ct.nt.promot.d lysozyme cryst.llizat.on was proposed.

关键词： Prot.in Cryst.llizat.on surf.ct.nt Lysozyme Molecular int.ract.on Mechanism

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Int.rmet.llic Compounds f.rmat.on in Dissimilar f.ict.on St.r Welding of.Mg/Cu Alloys

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Act. Met.llurgica Sinica(English Let.ers) 2024年第9期37卷 1523-1532页

作者： Xue Li Qingzhen Zhao Hao su Ji Chen Chuansong Wu MOE Key Lab f.r Liquid-Solid St.uct.re Evolut.on and Mat.rials Processing Institute of Materials JoiningShandong UniversityJinan250061China

Joining dissimilar Mg/Cu alloys was st.ll an int.act.ble problem because of.t.e excessive int.rmet.llic compounds(IMCs)and poor mechanical propert.es using convent.onal welding *** t.e present.st.dy,f.ict.on st.r welding was employed f.r t.e but. joining of.dissimilar AZ31B Mg-alloy and t. pure Cu ***-f.ee Mg/Cu joint. were obt.ined wit. Mg-RS and Cu-AS conf.gurat.on,at.a welding speed of.50 mm/min and t.ol rot.t.ng speeds of.325 r/min,625 r/min and 925 r/*** t.e joining int.rf.ce,bot. Mg_(2)Cu and MgCu_(2) IMC phases were observed,wit. a clear,unif.rm and cont.nuous IMCs layer composed of.t.o sub-layers,layer-A of.Mg+Mg_(2)Cu and layer-B of.Mg_(2)Cu+MgCu_(2).t.e maximum ult.mat. t.nsile st.engt. of.t.e Mg/Cu f.ict.on st.r welding joint.reached 130 MPa at.925 r/min due t. enhanced mechanical int.rlocking bet.een Mg and Cu,as well as suf.icient.met.llurgical bonding at.t.e joining int.rf.ce wit. an IMCs layer t.ickness in t.e range of.1.0-2.0μm.

关键词： f.ict.on st.r welding Magnesium Copper Int.rmet.llic compounds Mechanical propert.es

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Ext.act.on,chemical component.,bioact.ve f.nct.ons and adult.rat.on ident.f.cat.on of.walnut.oils:A review

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Grain & Oil Science and t.chnology 2024年第1期7卷 30-41页

作者： Yuan Gao Jia Hu Xia su Qi Li Caihong su Yongling Li Gaiqin Ma Siyu Zhang Xiuzhu Yu Engineering Research Cent.r of.Grain and Oil f.nct.onalized Processing College of Food Science and EngineeringNorthwest A&F UniversityShaanxi 712100China Animal Product. and Animal Medicine f.ed Qualit. Inspect.on Cent.r Hebei 050041China

Walnut.oil is a f.nct.onal wood oil known t. researchers t.at.may pot.nt.ally be a large source of.Chinese edible *** are various ext.act.on met.ods f.r walnut.oil,including t.adit.onal(pressing,solvent.and enzymeassist.d ext.act.on)and novel met.ods(microwave,ult.asound,supercrit.cal CO_(2),subcrit.cal and ot.er ext.act.on t.chnologies).Walnut.oil is rich in nut.ient.,including phyt.st.rols,t.copherols,polyphenols,squalene and *** provides many healt. benef.t.,such as ant.oxidant.ant.t.mor,ant.-inf.ammat.ry,ant.diabet.c and lipid met.bolism-relat.d *** addit.on,t.e aut.ent.cat.on of.walnut.oil has received much research *** present.review provides det.iled research on walnut.oil ext.act.on,composit.on,healt. benef.t. and adult.rat.on ident.f.cat.on *** pat. t.ward f.rt.er walnut.oil improvement.in t.e cont.xt.of.t.e market.value of.walnut.oil is also discussed.

关键词： Ext.act.on t.chnology Chemical composit.on Bioact.ve Aut.ent.cat.on

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Molecular Dynamics Simulat.on St.dies on t.e Micromorphology and Prot.n t.ansport.of.Naf.on/t._(3)C_(2)t.(x) Composit. Membrane

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Chinese Journal of.Polymer Science 2024年第3期42卷 373-387,I0009页

作者： Zhi-Yue Han su-Peng Pei Chun-Yang Yu Yong-f.ng Zhou School of.Chemical and Environment.l Engineering Shanghai Institute of TechnologyShanghai 201418China School of.Chemist.y&Chemical Engineering Frontiers Science Center for Transformative MoleculesShanghai Key Laboratory of Electrical Insulation and Thermal AgingShanghai Jiao Tong UniversityShanghai 200240China Key Laborat.ry of.Green and High-end Ut.lizat.on of.Salt.Lake Resources Chinese Academy of SciencesXining 810008China

t.e perf.uorosulf.nic acid(Pf.A) membrane doped wit. t.o-dimensional conduct.ve f.ller t._(3)C_(2)t.(x) is a f.el cell prot.n exchange membrane wit. high applicat.on pot.nt.al. Experiment.l st.dies showed t.at.t.e prot.n conduct.vit. of.Naf.on/t._(3)C_(2)t.(x) composit. membrane is improved signif.cant.y compared wit. t.at.in pure Naf.on. However, t.e microscopic mechanism of.doping on t.e enhancement.of.membrane perf.rmance is remain unclear now. In t.is work, molecular dynamics simulat.on was used t. invest.gat. t.e microscopic morphology and prot.n t.ansport.behaviors of.Naf.on/t._(3)C_(2)t.(x) composit. membrane at.t.e molecular level. t.e result. shown t.at.t.ere were signif.cant.dif.erences about.t.e dif.usion kinet.cs of.wat.r molecules and hydroxium ions in Naf.on/t._(3)C_(2)t.(x) at.low and high hydrat.on levels in t.e nanoscale *** t.e increase of.wat.r cont.nt. t._(3)C_(2)t.(x) in membrane was gradually surrounded by ambient.wat.r molecules t. f.rm a hydrat.on layer, and f.rming a relat.vely cont.nuous prot.n t.ansport.channel bet.een Naf.on polymer and t._(3)C_(2)t.(x) monomer. t.e cont.nuous prot.n t.ansport.channel could increase t.e number of.binding sit.s of.prot.n and t.us achieving high prot.n conduct.vit. and high mobilit. of.wat.r molecules at.higher hydrat.on level. t.e current.work can provide a t.eoret.cal guidance f.r designing new t.pe of.Naf.on composit. membranes.

关键词： Naf.on/t._(3)C_(2)t.(x)composit. membrane Prot.n t.ansport Molecular dynamics simulat.on

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Engineered plant.ext.acellular vesicles f.r aut.immune diseases t.erapy

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Nano Research 2024年第4期17卷 2857-2873页

作者： Ruina Han Yan Wu Yaf.i Han Xiangf.i Liu Han Liu Jiacan su Inst.t.t. of.t.anslat.onal Medicine Shanghai UniversityShanghai 200444China Organoid Research Cent.r Shanghai UniversityShanghai 200444China Nat.onal Cent.r f.r t.anslat.onal Medicine(Shanghai)SHU Branch Shanghai UniversityShanghai 200444China Depart.ent.of.Ort.opedics Shanghai Zhongye HospitalShanghai 200941China Depart.ent.of.Ort.opedics Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China

Aut.immune diseases(AID)encompass a diverse array of.condit.ons charact.rized by immune syst.m dysregulat.on,result.ng in aberrant.responses of.B cells and t.cells against.t.e body’s own healt.y *** ext.acellular vesicles(PEVs)are nanoscale part.cles enclosed by phospholipid bilayers,secret.d by plant.cells,which f.cilit.t. int.rcellular communicat.on by t.ansport.ng various bioact.ve *** t. t.eir nanoscale st.uct.re,saf.t.,abundant.sources,low immunogenicit.,high yield,biocompat.bilit.,and ef.ect.ve t.rget.ng of.t.e colon and liver,PEVs are regarded as a promising plat.orm f.r t.e t.eat.ent.of.*** review provides a comprehensive summary of.PEV biogenesis,physicochemical and biological propert.es,int.rnalizat.on mechanisms,isolat.on met.ods,and t.eir applicat.ons in various diseases,wit. a specif.c f.cus on t.eir pot.nt.al roles in ***,we propose engineering approaches and administ.at.on met.ods f.r ***,we present.an overview of.t.e advant.ges and challenges associat.d wit. ut.lizing PEVs f.r t.e t.eat.ent.of.*** gaining a comprehensive underst.nding of.PEVs,we ant.cipat. t.e development.of.innovat.ve t.erapeut.c st.at.gies f.r *** and engineered PEVs hold subst.nt.al promise as a valuable resource f.r innovat.ve t.chnologies in AID t.eat.ent.

关键词： aut.immune diseases plant.ext.acellular vesicles ext.acellular vesicles engineering modif.cat.on

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t.ermoluminescence charact.rizat.on of.nat.ral and synt.et.c irradiat.d Ce-monazit.s

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Journal of.Rare Eart.s 2024年第4期42卷 643-650页

作者： V.Correcher C.Boronat.J.Garcia-Guinea J.f.Benavent. t.Rivera-Mont.lvo CIEMAt Av.Complutense 4028040MadridSpain MNCN-CSIC J.Gutierrez Abascal 228006MadridSpain Inst.t.t. Polit.cnico Nacional CICATA-IPNAv.Legaria 694Mexico City11500Mexico

t.e t.ermoluminescence(t.)emission of.synt.et.c and nat.ral Ce-monazit.s was charact.rized here t. det.rmine t.e pot.nt.al applicat.on in t.e ident.f.cat.on of.microscopic def.ct. f.om a qualit.t.ve point.of.view t.ying t. link each t. peak t. a chemical-physical *** kinet.c paramet.rs t.at.lead t.e luminescence processes were calculat.d by means of.variable heat.ng rat. and comput.ng glow curve deconvolut.on met.ods and allow ident.f.ing t.ree groups of.component. at.90,130 and 290℃(f.r t.e mineral sample)and~90,170,220,270 and 320℃(f.r t.e synt.et.c CePO_(4):Nd_(0.20),La_(0.25)).t.e main dif.erences appreciat.d in t.ese complex t. curves are mainly due t.(i)t.e cont.nt.of.impurit.es(nat.ral sample cont.ins lant.anides as well as U 0.60%and t. 5.22%)and(ii)t.e degree of.cryst.llinit. of.t.e samples which is direct.y relat.d t. t.e t.pe of.impurit.es(synt.et.c monazit. relies only on Nd and La).t.e behavior of.t.e dose response in t.e range of.1-8 Gy is similar f.r bot. samples;t.e t. int.nsit. increases linearly as t.e dose increases wit.out.changes in t.e posit.on of.t.e maxima,denot.ng f.rst.order kinet.c luminescence *** peak could be most.y associat.d wit. st.uct.ral def.ct.(i.e.,phase t.ansit.ons),chemical react.ons(i.e.,Ce3+?Ce4+redox react.on,dehydrat.on or dehydroxylat.on processes)or int.insic def.ct.(i.e.,f.enkel def.ct.,ODCs or NBOHCs).

关键词： t.ermoluminescence Kinet.cparamet.rs Phosphat. Ce-monazit. Def.ct. Rare eart.s

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Equit.ble t.t.l Coloring of.f.bonacci Graphs

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Journal of.Mat.emat.cal Research wit. Applicat.ons 2024年第2期44卷 143-151页

作者： Yong LI Chunling t.NG Senyuan su Yanan su School of.Inf.rmat.on Science and Elect.icit. Engineering Shandong Jiaotong University Depart.ent.of.Mat.emat.cs Simon Fraser University

t.e equit.ble t.t.l coloring of.a graph G is a t.t.l coloring such t.at.t.e numbers of.element. in any t.o colors dif.er by at.most.one. t.e smallest.number of.colors needed f.r an equit.ble t.t.l coloring is called t.e equit.ble t.t.l chromat.c number. t.is paper cont.ibut.s t. t.e equit.ble t.t.l coloring of.f.bonacci graphs f.,n. We det.rmine t.e equit.ble t.t.l chromat.c numbers of.f.,nf.r ? = 3, 4, 5 and propose a conject.re on t.at.f.r ? >= 6.

关键词： f.bonacci graph equit.ble t.t.l coloring equit.ble t.t.l chromat.c number

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A st.r-like phot.det.ct.r f.r angle-based light.sensing in 3D space

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Nano Research 2024年第8期17卷 7567-7573页

作者： Qi Pan Sisi Chen Hongf.i Xie Qiling Xu Meng su Yanlin Song College of.Chemist.y Zhengzhou UniversityZhengzhou 450051China Key Laborat.ry of.Green Print.ng CAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of Sciences(ICCAS)Beijing Engineering Research Center of Nanomaterials for Green Printing TechnologyBeijing National Laboratory for Molecular Sciences(BNLMS)Beijing 100190China Universit. of.Chinese Academy of.Sciences Beijing 100049China

t.e development.of.t.ree-dimensional(3D)space light.angle det.ct.on is vit.l in opt.cal t.chnology f.r applicat.ons such as 3D imaging,comput.r vision,and augment.d *** met.ods involve advanced sensors and algorit.ms,including t.me-of.light.cameras,which need mult.ple cameras and light.sources t. improve ***,it.is a great.challenge t. int.grat. t.ese complex component. int. compact.*** semiconduct.r st.uct.res of.er opt.cal resonance charact.rist.cs,enabling precise light.mat.er int.ract.on regulat.on.A 3D st.r-like phot.det.ct.r,f.bricat.d using a t.mplat. assist.nt.print.ng st.at.gy,demonst.at.s opt.cal resonances of.t.e subwavelengt. f.cade and t.e shielding ef.ect.of.spat.al *** achieves light.angle det.ct.on wit. t.e resolut.on of.10°in vert.cal space and t.e resolut.on of.36°in horizont.l space,making it.a promising prot.t.pe f.r various applicat.ons.

关键词： phot.det.ct.r light.angle det.ct.on print.ng subwavelengt. st.uct.re shielding ef.ect

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