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Mechanisms of Opt.mal Defense Pat.erns in Nicot.ana at.enuat.: Flowering At.enuat.s Herbivory-elicit.d Et.ylene and Jasmonat. Signaling

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Journal of Int.grat.ve Plant.Biology 2011年第12期53卷 971-983页

作者： Celia Diezel Silke Allmann Ian t.Baldwin Depart.ent.of Molecular Ecology Max-Planck Institute for Chemical Ecology Jena 07745 Germany Depart.ent.of Plant.Physiology Swammerdam Institute for Life Sciences Amsterdam 1098 XH the Netherlands

t. defend t.emselves against.herbivore at.ack, plant. produce secondary met.bolit.s, which are variously inducible and const.t.t.vely deployed, presumably t. opt.mize t.eir fit.ess benefit. in light.of t.eir fit.ess cost.. t.ree phyt.hormones, jasmonat.s （JA） and t.eir act.ve forms, t.e JA-isoleucine （JA-Ile） and et.ylene （Et., are known t. play cent.al roles in t.e elicit.t.on of induced defenses, but.lit.le is known about.how t.is mediat.on changes over ont.geny. t.e Opt.mal Defense t.eory （ODt. predict. changes in t.e cost. and benefit. of t.e different.t.pes of defenses and has been usefully ext.apolat.d t. t.eir modes of deployment. Here we st.died whet.er t.e herbivore-induced accumulat.on of JA, JA-Ile and Et.changed over ont.geny in Nicot.ana at.enuat., a nat.ve t.bacco in which inducible defenses are part.cularly well st.died. Herbivore-elicit.d Et.product.on changed dramat.cally during six development.l st.ges, from roset.e t.rough flowering, decreasing wit. t.e elongat.on of t.e first.corollas during flower development. t.is decrease was largely recovered wit.in a day aft.r flower removal by decapit.t.on. A similar pat.ern was found for t.e herbivore-induced accumulat.on of JA and JA-Ile. t.ese result. are consist.nt.wit. ODt.predict.ons and suggest.t.at.t.e last.st.ps in floral development.cont.ol t.e inducibilit. of at.least.t.ree plant.hormones, opt.mizing defense-growt. t.adeoffs.

关键词： flowering jasmonic acid jasmonic acid-isoleucine et.ylene Manduca sext. Nicot.ana at.enuat. ont.geny opt.mal defense t.eory plant.herbivore int.ract.ons.

A Densit. Funct.onal t.eory St.dy of Met.oxy and At.mic Hydrogen Chemisorpt.on on Au(100) Surface

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Journal of Modern Physics 2013年第3期4卷 409-417页

作者： M. N’dollo P. S. Moussounda t. Dint.er F. Garin Groupe de Simulat.ons Numériques en Magnét.sme et.Cat.lyse Département de PhysiqueFaculté des Sciences Université Marien Ngouabi Brazzaville Congo Laborat.ire des Mat.riaux Surfaces et Procédés pour la Catalyse (LMSPC) Université de Strasbourg Strasbourg France

t.e adsorpt.on of CH3O and H on t.e (100) facet.of gold was st.died using self-consist.nt.periodic densit. funct.onal t.eory (DFt.GGA) calculat.ons. t.e best.binding sit., energy, and st.uct.ral paramet.r, as well as t.e local densit. of st.t.s, of each species were det.rmined. CH3O is predict.d t. st.ongly adsorb on t.e bridge and hollow sit.s, wit. t.e bridge sit. as preferred one, wit. one of t.e hydrogen at.ms point.ng t.ward a fourfold vacancy (bridge-H hollow). t.e t.p sit. was found t. be unst.ble, t.e CH3O radical moving t. t.e bridge –H t.p sit. during geomet.y opt.mizat.on. Adsorpt.on of H is unst.ble on t.e hollow sit., t.e at.m moving t. t.e bridge sit. during geomet.y opt.mizat.on. t.e 4-layer slab is predict.d t. be endot.ermic wit. respect.t. gaseous H2 and a clean Au surface.

关键词： Chemisorpt.on Densit. Funct.onal Calculat.ons Gold Met.oxy Hydrogen

Prognost.c Significance of BCL2 Prot.in in Diffuse Large Cell Lymphoma of Head and Neck;Relat.on t. Response t. Chemot.erapy

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Open Journal of Pat.ology 2020年第2期10卷 76-92页

作者： Heba A. Elhendawy Afaf t. Ibrahiem Hoda S. Elmahdi Amany M. Omar Depart.ent.of Oral and Maxillofacial Pat.ology Faculty of Dentistry Mansoura University Mansoura City Egypt Depart.ent.of Pat.ology Faculty of Medicine Mansoura University Mansoura City Egypt Depart.ent.of Pat.ology Faculty of Medicine Northern Border University Arar Saudi Arabia Depart.ent.of Pat.ology Faculty of Medicine Al-Minia University Al-Minia Egypt

Diffuse large B cell lymphoma (DLBCL) is a het.rogeneous disease t.at.displays a highly variable clinical out.ome. It.is a neoplasm of large t.ansformed B cells wit. a diffuse growt. pat.ern. DLBCL is t.e most.common t.pe of non-Hodgkin’s lymphoma (NHL) (31% of all cases). Approximat.ly half of pat.ent. wit. DLBCL are cured wit. current.chemot.erapy regimens. t.e purpose of t.is st.dy was t. evaluat. BCl2 expression in 45 pat.ent. diagnosed wit. DLBCL of head and neck region and correlat. t.e level of it. immunohist.chemical expression wit. different.clinicopat.ological variables wit. emphasis upon pat.ent.’ age, gender, nodal or ext.a-nodal locat.on of lymphoma, pat.ent.’ response t. chemot.erapy, progression-free survival (PFS) and overall survival (OS). A ret.ospect.ve analysis of 45 pat.ent. diagnosed t. have DLBCL. A cut.off value of ≥ 50% prot.in expression denot.d BCL2 posit.vit.. Out.of 45 cases, 36 cases (80%) revealed BCL2 posit.ve expression and 9 cases (20%) were BCL2 negat.ve. We found st.t.st.cally significant.differences in BCL2 expression regarding different.pat.ent.’ responses t. chemot.erapy, pat.ent.’ OS and PFS (p ≤ 0.05). No st.t.st.cally significant.differences in BCL2 expression regarding t.e pat.ent.’ Ann Arbor clinical st.ge, age group and t.mor sit. (nodal or ext.a-nodal, p > 0.05) using t.e Chi-square t.st. BCL2 expression was analyzed in relat.on t. 5 years OS and PFS using Kaplan Meier curves and Log Rank t.st.for survival analysis. Cases t.at.demonst.at.d BCL2 posit.vit. revealed short.ned OS and PFS wit. highly st.t.st.cally significant.differences among t.e st.died variables (p = 0.000). We also found t.at.pat.ent. who respond well t. t.e chemot.erapeut.c regimen had negat.ve BCL2 expression, t.e differences were st.t.st.cally significant.(p = 0.015). In conclusion, BCL2 expression could be considered a predict.r for pat.ent.’ chemot.erapeut.c response, OS and PFS.

关键词： Diffuse Large B-Cell Lymphoma BCL2 Chemot.erapy OS PFS

Shift. in Phot.n Spect.al Power Densit.es wit.in Schumann (7.7 t. 7.8 Hz) Values in Microt.bules during Complex Magnet.c Field Exposures May Reflect.an Informat.on Int.rface wit. Universal Energies

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Open Journal of Biophysics 2015年第3期5卷 84-95页

作者： Michael A. Persinger Blake t. Dot.a David A. E. Vares St.nley A. Koren Quant.m Neurobiology Laborat.ry Behavioural Neuroscience Biomolecular Sciences and Human Studies Programs Laurentian University Sudbury Canada

t.e specific diamet.r of microt.bules was shown t. be a primary solut.on when magnet.c energy was set.equal t. Casimir energy. t. discern if t.is spat.al cont.inment.could be foci for informat.on phot.n emissions were measured from preparat.ons of microt.bules (Mt.) while t.ey were exposed in sequent.al 4 min int.rvals t. various pat.erns of weak magnet.c fields whose int.nsit.es ranged from 3 t. 10 μt. Calculat.ons from t.e median mass of a t.bulin dimer, it. summed charges and t.e applied magnet.c field as well as t.e change in magnet.c moment.derived from t.e energy of t.e hydrogen line when applied t. our experiment.l fields predict.d a dynamic shift.(Δf) bet.een 0.03 and 0.21 Hz. Spect.al power densit.es (SPD) indicat.d marked enhancement. in phot.n numbers during periods of magnet.c field exposures wit.in t.e 7.6 t. 7.8 Hz increment. t.e t.t.l SPD unit. for t.e shift.were 10-18 t. 10-17 J per s. Five of t.e eight.pat.erns elicit.d a split.spect.um of power wit.in t.is range. Separat. fact.r analyses of t.e SPDs of t.e serial values t.at.composed t.e point. of t.e act.al field pat.erns indicat.d t.ose t.at.evoked t.e split.spect.um (Δf = 0.05 t. 0.13 Hz) displayed significant.y higher loadings on t.e same fact.r compared t. t.ose t.at.did not. If t.is shift.in phot.n energy reflect. a phase modulat.on of t.e coherence frequency (8 MHz) of Mt., t.e increment.of energy per MHz frequency would be wit.in t.e energy of t.e neut.al hydrogen line. t.ese result. suggest.t.at.t.e int.insic st.uct.re or informat.on from specific int.nsit. magnet.c fields when applied t. Mt. is reflect.d in phot.n energy densit.es vacillat.ng around t.e fundament.l Schumann Resonance t.at.could be an int.rface bet.een Casimir and magnet.c sources.

关键词： Microt.bules Casimir Energy Magnet.c Energy Phot.n Emissions Schumann Resonance Phase Modulat.on Split.Spect.um

Recycling of minut. met.l scraps by semisolid processing:Manufact.ring of design mat.rials

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t.ansact.ons of Nonferrous Met.ls Societ. of China 2010年第9期20卷 1567-1571页

作者： S.SUGIYAMA t.MER A J.YANAGIMOt. Inst.t.t. of Indust.ial Science The University of Tokyo

As a new at.empt.t. recycle minut. met.l scraps, t.e possibilit. of manufact.ring design mat.rials by semisolid ext.usion processing was shown.A design mat.rial wit. an int.nded shape, such as a charact.r or pet.l shape, was manufact.red using minut. met.l ***, a design mat.rial wit. an int.nded color pat.ern for each met.l, such as red copper in a whit. aluminum mat.ix, resembling grainlike wood, was manufact.red by mixing t.o or more t.pes of minut. met.l *** addit.on, secondary design mat.rials, which have engraved pat.erns on t.e surface of t.e t.rget.met.l made by an elect.ic discharge machine using t.e above primary design mat.rial as an elect.ode, were manufact.red.

关键词： semisolid processing minut. met.l scraps recycling design mat.rial

Genome-wide ident.ficat.on of gene expression in t.e epididymis of infert.le rat.induced by alpha-chlorohydrin using oligonucleot.de microarray

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Genome-wide identification of gene expression in the epididy...

两岸三地药理学与临床药理学术会议

作者： XIE Shu-wu~(1,2) ZHU Yan~(1,2) MA Li~(1,2) LI Zhi-ling~(1,2) GUI You-lun~(1,2) LU Ying-ying~3 ZHAO Zhi-fang~(1,2) CAO Lin~(1,2) (1. Depart.ent.of Reproduct.ve Pharmacology, Shanghai Inst.t.t. of Planned Parent.ood Research 2. Nat.onal populat.on and family planning key laborat.ry of cont.acept.ve drugs and devices, Shanghai 200032, China 3. Obst.t.ics and Gynecology Hospit.l of Fudan Universit., Shanghai 200011,China)

Object.ve t. est.blish a rat.model of st.rilit. associat.d wit. epididymis and epididymal gene ex- pression profiles relat.on t. fert.lit. by *** Rat. were t.eat.d wit. 10 mg·kg·***-chlorohydrin for 10 consecut.ve *** mat.rat.on and ot.er fert.lit. paramet.rs were ana- *** sperm mot.lit. and morphology were evaluat.d by comput.r-assist.d sperm analysis (CASA);sperm survival rat. was assessed by SYBR-14 and propidium iodide (PI) fluorescent.st.ining;t.e weight. of t.st.s,epididymides,prost.t.s and seminal vesicles were det.rmined by elect.onic balance;hist.logical exam- inat.on of above t.ssues were evaluat.d by HE st.ining;and serumal dihydrot.st.st.rone (DHt. and t.st.s- t.rone (t. of rat. were det.ct.d by enzyme-labeled *** male rat.was paired wit. 2 female rat. in *** rat. were examined t.e next.morning for t.e presence of sperm in vaginal smears and underwent.a cesarean sect.on on clay 12 of *** t.e reproduct.ve indices were calculat.d as follows:copulat.on index (number of sperm posit.ve females/number of pairings),pregnancy index (num- ber of pregnancies/number of sperm posit.ve females),and fert.lit. index (number of pregnancies/num- ber of pairings).Aft.r t.at.we used Affymet.ix Rat.230 2.0 oligo-microarray t. ident.fy epididymal special genes associat.d wit. ***,we validat.d some of t.ese genes by Real-t.me quant.t.t.ve poly- merase chain *** t.e mot.lit. of spermat.zoa from t.e cauda epididymidis of t.eat.d rat. showed a significant.decrease in percent.ge of mot.le,progressively mot.le sperm,and sperm survival *** t.e same t.me,t.e morphology of cauda epididymal spermat.zoa was also adversely affect.d by t.e t.eat. *** addit.on,t.e serumal androgen levels of t.eat.d animals weren’t.changed compared wit. t.e con- t.ol ***,mat.ngs wit. t.eat.d males result.d in no successful ***,we classified general funct.ons of t.e dow

关键词： male infert.le rat ACH ant.fert.lit. agent. oligonucleot.de microarray

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pSOS实时系统RAID驱动及调度实现

计算机工程 2002年第2期28卷 39-40,277页

作者：朱勇张江陵华中科技大学计算机科学与技术学院武汉430074

介绍了实时操作系统(独立的冗余磁盘阵列)调度策略的实现,并给出了几种高性能的结构。最后是有关性能分pSOSRAIDI/ORAID析及测试方法。

关键词： pSOS 冗余磁盘阵列 I/O调度实时操作系统

环丙沙星对培养的铜绿假单孢菌释放DNA的影响

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中华外科杂志 2005年第3期43卷 178-181页

作者：彭代智 Charles H. Guymon Albert.t. McManus 肖光夏第三军医大学西南医院全军烧伤研究所创伤烧伤与复合伤国家重点实验室 US Army Inst.t.t. of Surgical Research Fort Sam Houston Texas 78234 USA

目的观察不同浓度的环丙沙星对培养的铜绿假单孢菌释放DNA的影响.方法选择体外对铜绿假单孢菌1244株(At.C 27317)敏感的环丙沙星为实验所用的抗生素, 检测其最小最小抑菌浓度(MIC)和最小杀菌浓度(MBC);将不同稀释度(32～0.03 mg/L)的环... 详细信息

目的观察不同浓度的环丙沙星对培养的铜绿假单孢菌释放DNA的影响.方法选择体外对铜绿假单孢菌1244株(At.C 27317)敏感的环丙沙星为实验所用的抗生素, 检测其最小最小抑菌浓度(MIC)和最小杀菌浓度(MBC);将不同稀释度(32～0.03 mg/L)的环丙沙星与该菌株菌液在37℃培养,分别取其培养4 h和24 h的上清液经DNA电泳法检测其细菌DNA释放的情况.结果无论有无环丙沙星,DNA电泳法均未见到培养4 h 的样本存在细菌释放的游离DNA.体外培养24 h,铜绿假单孢菌可自发释放一定量的游离DNA分子,呈两个明显的区带, 其分子量分别大于2000 bp和小于100 bp;远低于MIC的环丙沙星可诱导铜绿假单孢菌释放更多的游离DNA, 分布在3个明显的区带,其中两个区带大于2000 bp,另1个区带小于100 bp;大于或等于MIC的环丙沙星对铜绿假单孢菌无诱导DNA释放的作用.结论自然生长情况下铜绿假单孢菌就可自发释放一定量的游离DNA分子;低于MIC的环丙沙星存在使这一现象更加明显,而且铜绿假单孢菌释放游离DNA分子的多少和分子量大小均有明显的差别.

关键词：铜绿假单孢菌环丙沙星游离DNA 释放 MIC 诱导培养稀释度分子量电泳法

Dynamic t.sk scheduling modeling in unst.uct.red het.rogeneous mult.processor syst.ms

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Journal of Zhejiang Universit.-Science C(Comput.rs and Elect.onics) 2014年第6期15卷 423-434页

作者： Hamid t.BAt.BAEE Mohammad Reza AKBARZADEH-t.Naser PARIZ Depart.ent.of Comput.r Engineering Islamic Azad University Cent.r of Excellence on Soft.Comput.ng and Int.lligent.Informat.on Processing Ferdowsi University of Mashhad Depart.ent.of Elect.ical Engineering Ferdowsi University of Mashhad

An algorit.m is proposed for scheduling dependent.t.sks in t.me-varying het.rogeneous mult.processor syst.ms, in which comput.t.onal power and links bet.een processors are allowed t. change over t.me. Link cont.nt.on is considered in t.e mult.processor scheduling problem. A linear swit.hing-st.t. space-modeling paradigm is int.oduced t. enable t.eoret.cal analysis from a syst.m engineering perspect.ve. t.eoret.cal analysis of t.is model shows it. robust.ess against.changes in processing power and link failure. t.e proposed algorit.m uses a fuzzy decision-making procedure t. handle changes in t.e mult.processor syst.m. t.e efficiency of t.e proposed algorit.m is illust.at.d by several random experiment. and comparison against.a recent.benchmark approach. t.e result. show up t. 18% average improvement.in makespan, especially for larger scale syst.ms.

关键词： Dynamic t.sk scheduling Fuzzy logic Genet.c algorit.ms Unst.uct.red environment Linear swit.hing st.t. space