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Evaluation of periglacial landforms and formation of soil properties on the Mount Honaz,SW türkiye

Journal of Mountain Science 2024年第9期21卷 3047-3067页

作者： SERİN Soner UNCU Levent DEDE Volkan türkeşmurat Institute of Social Sciences İstanbul Universityİstanbul 34119Türkiye Department of Geography BilecikŞeyh Edebali UniversityBilecik 11234Türkiye Department of Geography Ardahan UniversityArdahan 75002Türkiye Center for Climate Change and Policy Studies Boğaziçi Universityİstanbul 34342Türkiye

the main aim of this study is to explain periglacial processes on the summits of Mount Honaz(2571 m a.s.l.),define periglacial landforms,and determine the relationships between morphometric features and topographic *** circles,stony earth circles,non sorted steps,and non sorted stripes were identified on the summits of Mount ***'s correlation coefficient(r)and linear regression analyses were performed by taking metric measurements from 125 periglacial landforms to describe their morphometric features(length,width,height)of periglacial landforms and explain the relationships between them and topographic factors(elevation,slope).to explain the relationships between periglacial landforms and soil properties,soil samples from 11 periglacial landforms were taken and *** landforms,which continue to develop on the summits of Mount Honaz today,have been evaluated with present climate *** of soil samples indicates a notable impact of parent material on the genesis of periglacial *** high ratio of organic matter in mud circle and non sorted step landforms and the high lime ratio in stony earth circle landforms prove a strong relationship between the formation mechanisms of landforms and the soil ***,it is consistent with the findings obtained from the analysis that severe periglacial processes and washing and scavenging events are experienced more on the northern slopes.

关键词： Periglacial processes and geomorphology Soil analysis Morphometric analysis Mount Honaz türkiye

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伊尔加兹山脉冰缘地貌发育和土壤形成及其气候的影响(土耳其黑海西岸)

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Journal of Geographical Sciences 2024年第3期34卷 543-570页

作者： DEDE Volkan DENGIZ Orhan DEMIRAG tURAN inci türkeS murat SENOL Hüseyin SERIN Soner Department of Geography Ardahan UniversityArdahan75002Türkiye Department of Soil Science and Plant Nutrition Faculty of AgricultureOndokuz Mayıs UniversitySamsun55139Türkiye Department of Geography Faculty of Human and Social SciencesSamsun UniversitySamsun55080Türkiye Center for Climate Change and Policy Studies Boğaziçi Universityİstanbul34342Türkiye Faculty of Agriculture Department of Soil Science and Plant NutritionIsparta University of Applied SciencesIsparta32200Türkiye Institute of Social Sciences İstanbul Universityİstanbul34119Türkiye

the main aims of the current study are to determine the morphological features of the periglacial landforms(non-sorted step,mud circle,stony earth circle,thufur,and congeliturbation)located on the Ilgaz Mountains,examine the physicochemical and mineralogical properties with pedological processes of the soils,and assess of the effects of climatic conditions controlling the development of *** Ilgaz Mountains(2587 m a.s.l.),located in the Western Black Sea Region,within the Anatolian Mountains,are important in terms of periglacial landforms(mud circles,stony earth circles,thufurs,non-sorted steps,non-sorted stripes,congeliturbation deposits,and block currents).the descriptive statistics of 123 periglacial landforms measured by fieldworks were *** distribution of freezing and thawing in the Ilgaz Mountains throughout the year was evaluated,and it was found that freezing takes place between December and March,freezing-thawing takes place in April,May,October and November,and thawing takes place between June and *** to soil properties,organic matter content changes from 1.88%to 12.72%in non-sorted step soils,while it is between 2.03%and 12.24%in stony earth circle *** organic matter is observed to be close to congeliturbation deposits at lower ratios compared to non-sorted steps,stony earth circles and mud *** soil reactions on stony earth circles and non-sorted steps vary between slightly acidic and slightly *** the other hand,soil samples taken from the mud circles are different from those taken from the non-sorted steps and stony earth *** soil reaction is acidic,and pH changes between 4.86 and *** lime content also varies between 2.81%and 32.08%,with an average of 12.02%.the texture properties of soils are dominantly loam and clay loam,as in the non-sorted steps,stony earth circles,and mud *** their mineralogical properties,the XRD study was carried out to determine the primer mineral

关键词： periglacial landforms soil formation climate effect Ilgaz Mountains türkiye

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Note on Lower triassic Gondolelloid Conodont Rediversifications with Emphasis on the Spathian Recovery

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Journal of Earth Science 2024年第4期35卷 1236-1242页

作者： Ali murat Kilic Department of Geological Engineering Faculty of EngineeringBalikesir UniversityBalikesir99100Turkey

Conodonts,as a biotic group,next to ammonoids,pollen and spores,crustaceans and vertebrates,provide proxy clues for environment and age assessments of the rocks in which they *** are widely used for triassic marine ***,there are various discussions about their multielement taxonomy and evolutionary lineages(e.g.,generation,speciation).Although first studies reported that most triassic conodont species were unimembrate,studies carried out in the following years maintained that all triassic conodonts were *** statistical reconstructions of a number of triassic apparatuses were attempted,the discovery of fused clusters and natural assemblages has subsequently demonstrated that triassic conodonts are indeed multimembrate,and all of the elements exist together in the same *** present paper aims to clarify the evolutionary relationship and array of some Lower triassic *** dagisi *** described.

关键词： triassic Spathian conodont Columbitella Siberia environmental geology

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Effect of a cervical collar on optic nerve sheath diameter in trauma patients

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World Journal of Emergency Medicine 2024年第2期15卷 126-130页

作者： Mümin murat Yazici Ozcan Yavasi Department of Emergency Medicine Recep Tayyip Erdogan University Training and Research HospitalRize 53020Türkiye

BACKGROUND:As advocated in advanced trauma life support and prehospital trauma life support protocols,cervical immobilization is applied until cervical spine injury is *** study aimed to show the difference in optic nerve sheath diameter(ONSD)between patients with and without a cervical collar using computed tomography(Ct).MEtHODS:this was a single-center,retrospective study examining trauma patients who presented to the emergency department between January 1,2021,and December 31,*** ONSD on brain Ct of the trauma patients was measured and analyzed to determine whether there was a difference between the ONSD with and without the cervical ***:the study population consisted of 169 *** Ct imaging of patients with(n=66)and without(n=103)cervical collars,the mean ONSD in the axial plane were 5.43±0.50 mm and 5.04±0.46 mm respectively for the right eye and 5.50±0.52 mm and 5.11±0.46 mm respectively for the left *** results revealed an association between the presence of a cervical collar and the mean ONSD,which was statistically significant(Pth the right and left ***:A cervical collar may be associated with increased *** effect of this increase in the ONSD on clinical outcomes needs to be investigated,and the actual need for cervical collar in the emergency department should be evaluated on a case-by-case basis.

关键词： Optic nerve sheath diameter Computed tomography trauma Emergency medicine

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Immunotherapy in gastric cancer with liver metastasis:Challenges and opportunities

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1513-1516页

作者： murat Bardakçi Yakup Ergun Department of Medical Oncology Diyarbakır Gazi Yasargil Training and Research HospitalDiyarbakir 021000KayapinarTürkiye Department of Medical Oncology Antalya City HospitalAntalya 07080Türkiye

In this editorial,we review the article by Liu et al published in the World Journal of Gastrointestinal Surgery investigating the efficacy and safety of immunotherapy in patients with gastric cancer(GC)and liver ***,the fifth most com-monly diagnosed malignancy worldwide,presents a significant challenge due to its multifactorial etiology and a grim prognosis for unresectable or recurrent *** advent of immune checkpoint inhibitors(ICIs)has revolutionized oncology;yet liver metastasis has been associated with reduced response rates,progression-free survival,and overall survival in various *** Che-ckMate-649 and KEYNOtE-859 trials demonstrated promising results with ICIs in advanced GC,particularly in patients with liver ***,a meta-analysis of liver metastatic solid tumors revealed worse outcomes with ICIs,high-lighting the need for further *** combined therapies,including ICIs with local treatments,show promise in improving outcomes,the nuanced landscape of ICIs in liver metastatic GC necessitates continued research for robust *** current contradictions in the literature underscore the impor-tance of cautious interpretation and the exploration of tailored approaches to enhance clinical efficacy in this challenging patient population.

关键词： Gastric cancer Liver metastasis Immunotherapy Immune checkpoint in-hibitors transarterial chemoembolization tumor microenvironment

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Semiotics and political discourse in the post-truth era

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Language and Semiotic Studies 2024年第1期10卷 65-82页

作者： BetülÇanakpınar murat Kalelioğlu V.Doğan Günay Istinye University IstanbulTürkiye School of Foreign Languages T C Mardin Artuklu UniversityMardinTürkiye Faculty of Literature Department of LinguisticsDokuz Eylül UniversityIzmirTürkiye

the concept of post-truth has been on the world’s agenda since *** this concept,which is frequently encountered in political life,provides the speaker with a freer speaking ***,instead of presenting the reality to their constituents as it is,want to reshape this reality according to their own ideology and present it to the *** have certain objectives in creating such a virtual *** aims can be listed as keeping the voters,increasing the voting potential,and attracting undecided voters to their *** common result of all these aims is to gain political power or to remain in the existing ***-truth reality is constructed relatively more easily in social media *** construction of reality can be through beliefs or *** such ways,the recipient is tried to be persuaded,and thus behavioral change is *** of the most necessary subjects for this artificial reality atmosphere is the *** idea that the anti-subject does not know the truth that we(you and I)know and believe and is trying to destroy it is the main theme of post-truth *** try to persuade the voters to believe in their own truth by expressing this idea to *** are many examples of this around the *** this study,firstly,the concept of post-truth is examined and its various definitions are *** distinctions between the concepts of real and truth are analyzed and then it is explained how and for what purposes the concept of post-truth is used in *** the comparison of post-truth and fake news,the concept is discussed within the framework of sender-receiver interaction in terms of *** concept is tried to be elucidated with the modalities such as/convincing/,/believing/,/being/,/appearing/.Besides,using the semiotic square,the study also tries to reveal the different purposes and forms of use of the concept of *** a result,it has been observed

关键词： semiotics discourse politics post-truth fake news

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Immunomodulatory activity of polycaprolactone nanoparticles with calcium phosphate salts against Leishmania infantum infection

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Asian Pacific Journal of tropical Biomedicine 2024年第8期14卷 359-368页

作者： Kübra Kelleci Adil Allahverdiyev Melahat Bağırova murat Ihlamur EmrahŞefik Abamor Department of Bioengineering Yildiz Technical UniversityIstanbulTurkey V.Akhundov National Scientific Research Medical Prophylactic Institute BakuAzerbaijan Department of Electronics and Automation Biruni UniversityIstanbulTurkey

Objective:to prepare and characterize polycaprolactone(PCL)nanoparticles loaded with sonicator fragmented(SLA)and freeze-thaw Leishmania antigens(FtLA)and to investigate the in vitro immunogenicity of antigen-encapsulated nanoparticles with calcium phosphate ***:the water/oil/water binary emulsion solvent evaporation method was used to synthesize antigen-loaded PCL *** were characterized by scanning electron microscopy and zeta potential *** cytotoxicity in J774 macrophages in vitro was determined by Mtt *** addition,the amount of nitric oxide and the level of cytokines produced by macrophages were determined by Griess reaction and ELISA method,*** protective effect of the developed formulations was evaluated by determining the infection index percentage in macrophages infected with Leishmania ***:Compared to the control group,SLA PCL and FtLA PCL nanoparticles with calcium phosphate adjuvant induced a 6-and 7-fold increase in nitric oxide,***,the vaccine formulations promoted the production of IFN-γand *** PCL and FtLA PCL nanoparticles combined with calcium phosphate adjuvant caused an approximately 13-and 11-fold reduction in infection index,respectively,compared to the control ***:the encapsulation of antigens obtained by both sonication and freeze-thawing into PCL nanoparticles and the formulations with calcium phosphate adjuvant show strong in vitro immune stimulating ***,PCL-based antigen delivery systems and calcium phosphate adjuvant are recommended as a potential vaccine candidate against leishmaniasis.

关键词： Leishmaniasis Calcium phosphate Polycaprolactone Nanoparticle Antigen delivery system Adjuvant Vaccine design

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Dynamic Pricing Strategies Using Artificial Intelligence Algorithm

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Open Journal of Applied Sciences 2024年第8期14卷 1963-1978页

作者： murat Basal Emel Saraç Kadir Özer Logistics Vocational School Istanbul Gelisim University Istanbul Turkey Department of Business Administration Institute of Social Sciences Ostim Technical University Ostim Turkey Department of Insurance Faculty of Financial Sciences Ankara Hac Bayram Veli University Ankara Turkey

Pricing strategies can have a huge impact on a company’s success. this paper focuses on the advantages and disadvantages of using artificial intelligence in dynamic pricing strategies. A good understanding of the possible benefits and challenges will help companies to understand the impact of their chosen pricing strategies. AI-driven Dynamic pricing has great opportunities to increase a firm’s profits. Firms can benefit from personalized pricing based on personal behavior and characteristics, as well as cost reduction by increasing efficiency and reducing the need to use manual work and automation. However, AI-driven dynamic rewarding can have a negative impact on customers’ perception of trust, fairness and transparency. Since price discrimination is used, ethical issues such as privacy and equity may arise. Understanding the businesses and customers that determine pricing strategy is so important that one cannot exist without the other. It will provide a comprehensive overview of the main advantages and disadvantages of AI-assisted dynamic pricing strategy. the main objective of this research is to uncover the most notable advantages and disadvantages of implementing AI-enabled dynamic pricing strategies. Future research can extend the understanding of algorithmic pricing through case studies. In this way, new, practical implications can be developed in the future. It is important to investigate how issues related to customers’ trust and feelings of unfairness can be mitigated, for example by price framing.

关键词： Artificial Intelligence Algorithm Dynamic Pricing Strategy

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Late Ordovician Mass Extinction: Earth, fire and ice

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National Science Review 2024年第1期11卷 51-65页

作者： David A.t.Harper Palaeoecosystems Group Department of Earth SciencesDurham University

the Late Ordovician Mass Extinction was the earliest of the ‘big’ five extinction events and the earliest to affect the trajectory of metazoan life. two phases have been identified near the start of the Hirnantian period and in the middle. It was a massive taxonomic extinction, a weak phylogenetic extinction and a relatively benign ecological extinction. A rapid cooling, triggering a major ice age that reduced the temperature of surface waters, prompted a drop in sea level of some 100 m and introduced toxic bottom waters onto the shelves. these symptoms of more fundamental planetary processes have been associated with a range of factors with an underlying driver identified as volcanicity. Volcanic eruptions, and other products, may have extended back in time to at least the Sandbian and early Katian, suggesting the extinctions were more protracted and influential than hitherto documented.

关键词： Ordovician LOME paleoecology palaeobiogeography biotas

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Preparation of microparticles and nanoparticles using membrane-assisted dispersion,micromixing,and evaporation processes

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Particuology 2024年第1期84卷 30-44页

作者： Goran t.Vladisavljevic Chemical Engineering Department Loughborough UniversityLoughboroughLeicestershire LE113TUUnited Kingdom

Synthetic microporous membranes are increasingly used for energy-efficient and controlled production of micro-and nanoparticles and micro-and nanoemulsions with tuneable morphology and physico-chemical properties through various micromixing,emulsification,and evaporation *** emul-sification processes,the membrane pores are used for dispersed phase injection and size-controlled generation of droplets and droplet-templated *** micromixing processes,membrane is utilised as a micromixer for mixing two miscible liquids,usually solvent and antisolvent-rich solutions,which leads to the creation of supersaturation and subsequent nanoprecipitation or *** mem-brane evaporation processes,membrane is used to prevent phase dispersion while allowing efficient molecular diffusion of solvent and/or antisolvent vapour through gas-filled *** dispersion processes can be operated continuously by decoupling shear stress on the membrane surface from cross flow using tube insets,flow pulsations,swirling flow,membrane oscillations or membrane *** generation and solidification can be performed continuously in a single pass by connecting membrane module with a downstream *** dispersion processes can be used for pro-duction of nanoparticles such as nanovesicles(liposomes,micelles,ethosomes,and niosomes),nanogels,polymeric,lipid and metallic nanoparticles,and *** main advantages of membrane-assisted particle generation are in low energy consumption,controlled geometry and hydrodynamic conditions at the microscale level,flexible throughput due to modular and scalable design of membrane devices,and a wide choice of available microporous membranes with various wall porosities,wetta-bilities,pore sizes,and pore morphologies to suit different applications.

关键词： Nanoparticles Microparticles Nanoemulsions Microemulsions Microporous membrane Crystallisation Flash nanoprecipitation Emulsification Zero liquid discharge

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