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Comparative assessment of clinical profile and outcomes after primary percutaneous coronary intervention in young patients with single vs multivessel disease

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World Journal of Cardiology 2020年第4期12卷 136-143页

作者： Atif Sher Muhammad Tariq Ashraf Ayaz Mir syed Alishan Faiza Farooq Ali Ammar Musa Karim syed nadeem hassan rizvi Tahir Saghir Jawaid Akbar Sial Naveed Ullah Khan Department of Adult Cardiology National Institute of Cardiovascular DiseasesKarachi 75510Pakistan Department of Clinical Research National Institute of Cardiovascular DiseasesKarachi 75510Pakistan

BACKGROUND Even though percutaneous coronary intervention(PCI)improved the survival of patients with acute myocardial infarction,still multivessel coronary artery disease remains an important factor burdening prognosis and it is being associated with a worse prognosis compared to single-vessel disease(SVD).AIM To compare the clinical profile and outcomes after the primary PCI in young patients with SVD vs multivessel disease(MVD).METHODS The retrospective cohort of patients were divided into two groups:SVD and MVD *** study population consisted of both male and female young(≤45 years)patients presented with ST-elevation myocardial infarction(STEMI)at the National Institute of Cardiovascular Disease,Karachi,Pakistan and undergone primary PCI from 1 st July 2017 to 31 st March *** and postprocedure management of the patients was as per the guidelines and institutional *** A total of 571 patients with STEMI,≤45 years were stratified into two groups by the number of vessels involved,342(59.9%)with SVD and 229(40.1%)with *** average age of these patients was 39.04±4.86 years.A lower prevalence of hypertension and diabetes was observed in SVD as compare to MVD group(25.1%vs 38%,P<0.01;11.7%vs 27.5%,P<0.001)***,smoking was more prevalent among the SVD group as compare to MVD group(36.3%vs 28.4%,P=0.05).The high-C Lesion was observed in a significantly higher number of younger patients with MVD as compared to SVD group(48.8%vs 39.2%,P=0.021).Post-procedure thrombolysis in myocardial infarction flow grade was found to be not associated with the number of diseased vessels with a P value of 0.426 and thrombolysis in myocardial infarction flow grade III was observed in 98%vs 96.5%of the patients is SVD vs MVD *** The MVD comprised of around 40%of the young patients presented with ***,this study shows that diabetes and hypertension have a certain role in the pathogenesis of multivessel diseases,therefore,preventive

关键词： Young Multivessel disease Primary percutaneous coronary intervention STelevation myocardial infarction Premature coronary artery diseases Single-vessel disease

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Conservation laws,Lie symmetries,self adjointness,and soliton solutions for the Selkov–Schnakenberg system

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Communications in Theoretical Physics 2024年第2期76卷 29-44页

作者： Kashif Ali Aly R Seadawy syed T R rizvi Noor Aziz Department of Mathematics COMSATS University IslamabadLahore CampusPakistan Mathematics Department Faculty of ScienceTaibah UniversityAl-Madinah Al-Munawarah41411Saudi Arabia

In this article,we explore the famous Selkov–Schnakenberg(SS)system of coupled nonlinear partial differential equations(PDEs)for Lie symmetry analysis,self-adjointness,and conservation ***,miscellaneous soliton solutions like dark,bright,periodic,rational,Jacobian elliptic function,Weierstrass elliptic function,and hyperbolic solutions of the SS system will be achieved by a well-known technique called sub-ordinary differential *** these results are displayed graphically by 3D,2D,and contour plots.

关键词： Selkov-Schnakenberg system Lie symmetry analysis conservation laws adjointness integrability

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Systematic Review:Load Balancing in Cloud Computing by Using Metaheuristic Based Dynamic Algorithms

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Intelligent Automation & Soft Computing 2024年第3期39卷 437-476页

作者： Darakhshan syed Ghulam Muhammad Safdar rizvi Department of Computer Science Bahria UniversityKarachi CampusKarachiPakistan

Cloud Computing has the ability to provide on-demand access to a shared resource *** has completely changed the way businesses are managed,implement applications,and provide *** rise in popularity has led to a significant increase in the user demand for ***,in cloud environments efficient load balancing is essential to ensure optimal performance and resource *** systematic review targets a detailed description of load balancing techniques including static and dynamic load balancing ***,metaheuristic-based dynamic load balancing algorithms are identified as the optimal solution in case of increased *** a cloud-based context,this paper describes load balancing measurements,including the benefits and drawbacks associated with the selected load balancing *** also summarizes the algorithms based on implementation,time complexity,adaptability,associated issue(s),and targeted QoS ***,the analysis evaluates the tools and instruments utilized in each investigated ***,comparative analysis among static,traditional dynamic and metaheuristic algorithms based on response time by using the CloudSim simulation tool is also ***,the key open problems and potential directions for the state-of-the-art metaheuristic-based approaches are also addressed.

关键词： Cloud computing load balancing metaheuristic algorithm dynamic algorithm load balancer QoS

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Chemical constituents and anticoagulant activity from Delphinium brunonianum Royle

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未来食品学报(英文) 2024年第3期4卷 241-247页

作者： Changyang Ma Sitan Chen syed Arif Hussain rizvi Huihui Zhou Wenyi Kang Xuefeng Xi Zhenhua Liu National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Joint International Research Laboratory of Food&Medicine Resource Function Henan ProvinceKaifeng 475004China Pakistan Agricultural Research Council Islamabad 450000Pakistan College of Physical Education Henan UniversityKaifeng 475004China

Delphinium brunonianum Royle belongs to Ranunculaceae family and has the effects of dispelling wind to relieve itching and cooling blood to *** was found that the extracts of *** had good anticoagulant activity which was extracted with 70%ethanol in our previous ***,16 compounds were isolated and identified from the extract of ***,among which compounds 5,7-10,12,14,15-16 were isolated from this genus for the first time,and compounds 2-4 were isolated from this plant for the first *** the coagulation activity assay showed that compounds 10,14 and 15 had good anticoagulant activity by activated partial thromboplastin time(APTT),thrombin time(TT)and prothrombin time(PT)in vitro.

关键词： Delphinium brunonianum Royle 9-Hydroxy-megastigma-4,7-dien-3-one-9-β-Dglucopyranoside 4-O-α-D-Glucosyl benzoic acid Isolariciresinol 4-O-β-D-glucopyranoside Anticoagulant activity

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Developing Transparent IDS for VANETs Using LIME and SHAP:An Empirical Study

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Computers, Materials & Continua 2023年第12期77卷 3185-3208页

作者： Fayaz hassan Jianguo Yu Zafi Sherhan syed Arif Hussain Magsi nadeem Ahmed Beijing Key Laboratory of Work Safety Intelligent Monitoring School of Electronic EngineeringBeijing University of Post and TelecommunicationBeijing100876China Department of Telecommunication Engineering Mehran University of Engineering and TechnologyJamshoro76062Pakistan State Key Laboratory of Networking and Switching Technology Beijing University of Post and TelecommunicationBeijing100876China School of Electronic Science Beijing University of Post and TelecommunicationBeijing100876China

Vehicular Ad-hoc Networks(VANETs)are mobile ad-hoc networks that use vehicles as nodes to create a wireless *** VANETs offer many advantages over traditional transportation networks,ensuring security in VANETs remains a significant challenge due to the potential for malicious *** study addresses the critical issue of security in VANETs by introducing an intelligent Intrusion Detection System(IDS)that merges Machine Learning(ML)–based attack detection with Explainable AI(XAI)*** study ML pipeline involves utilizing correlation-based feature selection followed by a Random Forest(RF)classifier that achieves a classification accuracy of 100%for the binary classification task of identifying normal and malicious *** innovative aspect of this study is the incorporation of XAI methodologies,specifically the Local Interpretable Model-agnostic Explanations(LIME)and SHapley Additive exPlanations(SHAP).In addition,this research also considered key features identified by mutual information-based feature selection for the task at *** major findings from this study reveal that the XAI-based intrusion detection methods offer distinct insights into feature *** features identified by mutual information,LIME,and SHAP predominantly relate to Transmission Control Protocol(TCP),Hypertext Transfer Protocol(HTTP),Domain Name System(DNS),and Message Queuing Telemetry Transport(MQTT)protocols,highlighting their significance in distinguishing normal and malicious network *** XAI approach equips cybersecurity experts with a robust means of identifying and understanding VANET malicious activities,forming a foundation for more effective security countermeasures.

关键词： Intrusion detection system machine learning security vehicular networks

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Development of a Bias Compensating Q-Learning Controller for a Multi-Zone HVAC Facility

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IEEE/CAA Journal of Automatica Sinica 2023年第8期10卷 1704-1715页

作者： syed Ali Asad rizvi Amanda J.Pertzborn Zongli Lin IEEE the Department of Electrical and Computer Engineering Tennessee Technological UniversityCookevilleTN 38505 USA the Mechanical Systems and Controls Group in the Building Energy and Environment Division at the National Institute of Standards and Technology(NIST) GaithersburgMD 20899 USA the Charles L.Brown Department of Electrical and Computer Engineering University of VirginiaCharlottesvilleVA 22904-4743 USA

We present the development of a bias compensating reinforcement learning(RL)algorithm that optimizes thermal comfort(by minimizing tracking error)and control utilization(by penalizing setpoint deviations)in a multi-zone heating,ventilation,and air-conditioning(HVAC)lab facility subject to unmeasurable disturbances and unknown *** is shown that the presence of unmeasurable disturbance results in an inconsistent learning equation in traditional RL controllers leading to parameter estimation bias(even with integral action support),and in the extreme case,the divergence of the learning *** demonstrate this issue by applying the popular Q-learning algorithm to linear quadratic regulation(LQR)of a multi-zone HVAC environment and showing that,even with integral support,the algorithm exhibits bias issue during the learning phase when the HVAC disturbance is unmeasurable due to unknown heat gains,occupancy variations,light sources,and outside weather *** address this difficulty,we present a bias compensating learning equation that learns a lumped bias term as a result of disturbances(and possibly other sources)in conjunction with the optimal control *** results show that the proposed scheme not only recovers the bias-free optimal control parameters but it does so without explicitly learning the dynamic model or estimating the disturbances,demonstrating the effectiveness of the algorithm in addressing the above challenges.

关键词： HVAC control optimal tracking Q-learning reinforcement learning(RL)

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Suppression of methane formation during Fisher-Tropsch synthesis using manganese-cobalt oxide supported on H-5A zeolite as a catalyst

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Journal of Natural Gas Chemistry 2009年第2期18卷 187-190页

作者： syed Tajammul Hussain Muhammad Mazhar Muhammad Arif nadeem National Centre for Physics Quaid-i-Azam UniversityIslamabad 43520 Pakistan Department of Chemistry Quaid-i-Azam UniversityIslamabad 43520 Pakistan

In Fischer-Tropsch synthesis reaction, methane formation is one of the side reactions which must be suppressed in order to get better catalytic selectivity for light olefins. In the present study, we have modified cobalt based Fischer-Tropsch catalyst and developed a process to minimize methane production, consequently to produce maximum yield of light olefins. Manganese-cobalt oxide supported on H-5A zeolite catalyst was synthesized using modified H-5A zeolite, to increase its surface acid sites. Increased acidity of zeolite plays a major part in the suppression of methane formation during the Fischer-Tropsch reaction. The modified zeolite results in the electronic modification of catalyst surface by creating new active catalytic sites. The results are compared with other supported catalysts along with unmodified zeolite. Appreciable reduction in methane formation is achieved on modified zeolite supported catalyst in comparison with unsupported catalyst.

关键词： methane formation Fisher-Tropsch synthesis manganese cobalt suppression

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Interaction properties of solitons for a couple of nonlinear evolution equations

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Chinese Physics B 2021年第1期30卷 185-190页

作者： syed Tahir Raza rizvi Ishrat Bibi Muhammad Younis Ahmet Bekir Department of Mathematics COMSATS University IslamabadLahore CampusPakistan Punjab University College of Information Technology University of the PunjabLahorePakistan Neighbourhood of Akcaglan Imarli Street Number 28/426030EskisehirTurkey

We study one-and two-soliton solutions for the Cahn–Allen(CA) equation and the Brethorton equation. The CA equation has broad spectrum of applications especially in anti-phase boundary motion and it is used in phase-field *** the Brethorton equation is a model for dispersive wave systems, it is used to find the resonant nonlinear interaction among three linear modes. We use the Hirota bilinear method to obtain one-and two-soliton solutions to the CA equation and the Brethorton equation.

关键词： Hirota bilinear method soliton interaction evolution equations

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Approach to pseudomyxoma peritonei

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World Journal of Gastrointestinal Surgery 2018年第5期10卷 49-56页

作者： syed Ali rizvi Wajahat syed Ravi Shergill Undergraduate Medicine McMaster University Department of Radiology McMaster University

Pseudomyxoma peritonei(PMP) is a mucinous tumour of the appendix that spreads into the peritoneal cavity in the form of gelatinous deposits. The incidence of PMP is believed to be approximately 1-3 out of a million per year. Nonetheless, due to its indolent nature, it is usually discovered at an advanced stage and severely impacts quality of life. Curative treatment for PMP is complete cytoreductive surgery(CRS) with hyperthermic intraperitoneal chemotherapy(HIPEC). An extensive literature review was conducted searching EMBASE, MEDLINE, Pub Med, and Google Scholar databases for PMP in aims to delineate a clinical approach to diagnosis and treatment. Literature was limited to the years 2007-2018. We found the 5-year overall survival with CRS and HIPEC estimated to be between 23%-82% and rates of major complications as high as 24%. Therefore, it is important to appropriately stage and select patients that should undergo CRS with HIPEC. Modalities like MDCT radiological scores have been shown to have sensitivity and specificity of 94% and 81%, respectively, in being able to predict resectability and survival. Despite treatment, the disease often recurs. Tumor markers have significant potential for establishing prognosis preoperatively, and this paper will review the most recent evidence in support of them.

关键词： Pseudomyxoma peritonei Cytoreductive surgery Hyperthermic intraperitoneal chemotherapy Mucocele Appendix

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Diffusion Based Channel Gains Estimation in WSN Using Fractional Order Strategies

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Computers, Materials & Continua 2022年第2期70卷 2209-2224页

作者： Nasir Mahmud Khokhar Muhammad nadeem Majeed syed Muslim Shah Department of Computer Engineering University of Engineering and TechnologyTaxila47050Pakistan Punjab University College of Information Technology University of PunjabLahore54000Pakistan Department of Electrical Engineering Capital University of Science and TechnologyIslamabad44000Pakistan

In this study,it is proposed that the diffusion least mean square(LMS)algorithm can be improved by applying the fractional order signal processing *** of Caputo’s fractional derivatives are considered in the optimization of cost *** is suggested to derive a fractional order variant of the diffusion LMS *** applicability is tested for the estimation of channel parameters in a distributed environment consisting of randomly distributed sensors communicating through wireless *** topology of the network is selected such that a smaller number of nodes are *** the network,a random sleep strategy is followed to conserve the transmission power at the *** proposed fractional ordermodified diffusionLMS algorithms are applied in the two configurations of combine-then-adapt and *** average squared error performance of the proposed algorithms along with its traditional counterparts are evaluated for the estimation of the Rayleigh channel *** proof of convergence is provided showing that the addition of the nonlinear term resulting from fractional derivatives helps adjusts the autocorrelation matrix in such a way that the spread of its eigenvalues *** increases the convergence as well as the steady state response even for the larger step *** results are shown for different number of nodes and fractional *** simulation results establish that the accuracy of the proposed scheme is far better than its classical counterparts,therefore,helps better solves the channel gains estimation problem in a distributed wireless *** algorithm has the potential to be applied in other applications related to learning and adaptation.

关键词： Diffusion strategies distributed channel gains fractional derivatives mean squared error

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