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Intermittent fasting and the liver: Focus on the Ramadan model

World Journal of Hepatology 2024年第8期16卷 1070-1083页

作者： Mohamed H Emara Hanan Soliman Ebada M Said hassan Elbatae Mostafa Elazab Shady Elhefnawy Tarik I Zaher ahmed Abdel-Razik Mohamed Elnadry Department of Hepatology Gastroenterology and Infectious DiseasesKafrelsheikh UniversityKafr-Elshikh 33516Egypt Department of Medicine Alyousif HospitalAlkhobar 34622Saudi Arabia Department of Tropical Medicine and Infectious Diseases Tanta UniversityTanta 31512Egypt Department of Hepatology Gastroenterology and Infectious DiseasesBenha UniversityBenha 13511Egypt Department of Tropical Medicine Zagazig UniversityZagazig 44519Egypt Department of Tropical Medicine Mansoura UniversityMansoura 35516Egypt Department of Hepato-Gastroenterology and Infectious Diseases Al-Azhar UniversityCairo 11651Egypt

Intermittent fasting(IF)is an intervention that involves not only dietary modific-ations but also behavioral changes with the main core being a period of fasting alternating with a period of controlled *** duration of fasting differs from one regimen to *** fasting(RF)is a religious fasting for Muslims,it lasts for only one month every one lunar *** this model of fasting,observers abstain from food and water for a period that extends from dawn to *** period of daily fasting is variable(12-18 hours)as Ramadan rotates in all seasons of the ***,longer duration of daily fasting is observed during the *** fact,RF is a peculiar type of *** is a dry IF as no water is allowed during the fasting hours,also there are no calorie restrictions during feeding hours,and the mealtime is exclusively *** three variables of the RF model are believed to have a variable impact on different liver *** was evaluated by different observational and interventional studies among patients with non-alcoholic fatty liver disease and it was associated with improve-ments in anthropometric measures,metabolic profile,and liver biochemistry regardless of the calorie restriction among lean and obese *** situation is rather different for patients with liver *** was associated with adverse events among patients with liver cirrhosis irrespective of the underlying etiology of *** patients developed new ascites,ascites were increased,had higher serum bilirubin levels after Ramadan,and frequently developed hepatic encephalopathy and acute upper gastrointestinal *** complications were higher among patients with Child class B and C cirrhosis,and some fatalities occurred due to *** transplant recipients as a special group of patients,are vulnerable to dehydration,fluctuation in blood immunosuppressive levels,likelihood of deterioration and hence observing RF without special precautions

关键词： Intermittent fasting Ramadan fasting Non-alcoholic fatty liver disease Liver cirrhosis Peptic ulcer Liver transplantation Gilbert syndrome

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Factors Promoting Retention of Nurses in Three Private Hospitals of Lahore: A Cross Sectional Descriptive Survey

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Open Journal of Nursing 2024年第7期14卷 344-367页

作者： Zainab Suleman Najma Balquees Anwar Sadaf Younis Alya Bilquees Anwar Naeema Khan syed Saemul hassan College of Nursing University of Health Sciences Lahore Lahore Pakistan

Introduction: Pakistan has a large number of professional nurses but a higher rate of turnover contributes towards the shortage of nurses which is intensified by nurses’ immigration, lack of recruitment of new nurses and retirement of senior nurses. Aim: The study aimed at examining the factors that increase retention of nurses. Research Method: The study is descriptive cross sectional with a sample of 150 nurses including both the genders, from 3 private hospitals located in Pakistan. A convenient sampling technique was used. The data collection was done through close ended questionnaires based on 20 questions. Data collection was done quantitatively and then data was entered in SPSS. Correlation and regression tests were performed. Findings: The analysis revealed that 91.3% nurses are loyal to their hospitals but, 8.7%nurses can switch the hospital for different reasons. It was also found that the idea of leaving the job based on the intention of moving to abroad and public sector was higher than the retirement and other causes. Resultantly, enhancements in nurses’ work environments have the ability to decrease nurses’ job burnout and turnover and increase patients’ satisfaction. Recommendations: Hospital leaders should implement effective strategies to encourage nurses to continue their job by motivation, strengthening management skills within the hospital and improving a positive work environment by promoting teamwork, continuous learning, trust, respect and flexible arrangements which can lead towards achieving better ***, further studies quantitatively and qualitatively can explore more factors related to dissatisfaction of nurses. Health systems policy makers should lead by developing related strategies for the retention of nurses.

关键词： Retention of Nurses Shortage of Nurses Turnover Workforce

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Immobilization techniques for beverage production using yeast cell systems: challenges, types, and future perspectives - a mini review

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Food and Health 2024年第4期6卷 27-38页

作者： syed Sib Tul hassan Shah Iqra Naeem Aimen Naeem Nabeel Khalid Bhutta Fatima Noor Zhejiang Province Key Laboratory of Plant Secondary Metabolism and Regulation College of Life Sciences and MedicineZhejiang Sci-Tech UniversityHangzhou310018China School of Biological Sciences University of the PunjabLahorePakistan Laboratory of Anti-allergic Functional Molecules College of Life Sciences and MedicineZhejiang Sci-Tech UniversityHangzhouZhejiang310018China Department of Zoology Government College UniversityFaisalabadPunjabPakistan

Yeast immobilization is a process of physical entrapment of yeast cells using different techniques while maintaining their biological *** fermentation systems have significant advantages over conventional *** highlights that immobilized yeast cell systems have several benefits as compared to free yeast *** immobilized yeast cell systems improve fermentation rates,especially when paired with continuous fermentation and appropriate immobilization *** various immobilization techniques,continuous fermentation processes,yeast metabolic activity related to beverage flavor production,and bioreactor designs is vital for optimizing the use of immobilized yeast cells systems on industrial *** review provides an overview of recent basic research on immobilized yeast cell systems,with a focus on continuous beverage *** this study,different reactor configurations and immobilization techniques are *** study focus on the impacts of immobilization on the yeast cells,and discuss the recent advancements in these *** review concludes with a discussion on the practical applications of immobilized yeast cells and continuous fermentation in beverage production.

关键词： Yeast Cell System Beverages Continuous Fermentation Microbial System

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Practical approach to linear endoscopic ultrasound examination of the gallbladder

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World Journal of Radiology 2024年第6期16卷 184-195页

作者： Hussein hassan Okasha Eyad Gadour hassan Atalla Omar AbdAllah AbdEl-Hameed Reem Ezzat ahmed Elsayed Alzamzamy Elsayed Ghoneem Rasha Ahmad Matar Zeinab hassan Bogdan Miutescu Ayman Qawasmi Katarzyna M Pawlak ahmed Elmeligui Department of Internal Medicine Division of Gastroenterology and HepatologyKasr Al-Aini School of MedicineCairo UniversityCairo 11562Egypt Department of Gastroenterology and Hepatology King Abdulaziz Hospital-National GuardAhsa 31982Saudi Arabia Department of Medicine School of MedicineZamzam University CollegeKhartoum 11113Sudan Department of Internal Medicine Hepatology and Gastroenterology UnitFaculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Internal Medicine Faculty of MedicineAssiut UniversityAssiut 71511Egypt Department of Gastroenterology and Heptology Maadi Armed Forces Medical ComplexMilitary Medical AcademyCairo 11728Egypt Department of Gastroenterology and Advance Endoscopy Sultant Qaboos Comprehensive Cancer Care and Research CentreMuscat 0961Oman Department of Internal Medicine Stockport Hospitals NHS Foundation TrustManchester SK27JEUnited Kingdom Department of Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 300041Romania Advanced Regional Research Centre in Gastroenterology and Hepatology Victor Babes University of Medicine and PharmacyTimisoara 30041Romania Department of Gastroenterology Al-Makassed Islamic Charitable Society HospitalCairo 11124Egypt Division of Gastroenterology St.Michael’s HospitalUniversity of TorontoToronto M5B 1W8Canada Department of Gastroenterology Southend University HospitalEssex SS26XTUnited Kingdom

The gallbladder(GB)is a susceptible organ,prone to various pathologies that can be identified using different imaging *** ultrasound(TUS)is typically the initial diagnostic method due to its numerous well-established ***,in cases of uncertainty or when a definitive diagnosis cannot be established,computed tomography(CT)or magnetic resonance imaging may be employed to provide more detailed ***,CT scans may sometimes offer inadequate spatial resolution,which can limit the differentiation of GB lesions,particularly when smaller yet clinically relevant abnormalities are ***,endoscopic ultrasound(EUS)provides higher frequency compared to TUS,superior spatial resolution,and the option for contrast-enhanced harmonic imaging,enabling a more comprehensive ***,EUS can serve as a supplementary tool when conventional imaging methods are *** review will describe the standard EUS examination of the GB,focusing on its endosonographic characteristics in various GB path-ologies.

关键词： Endoscopic ultrasound Linear endoscopic ultrasound Gallbladder anatomy Gallbladder pathologies Therapeutic endoscopic ultrasound

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National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider syed Mujahid hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan Rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

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Simultaneous Compression of the Celiac Trunk, Superior Mesenteric Artery, and Renal Arteries by the Median Arcuate Ligament: About One Case

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Open Journal of Medical Imaging 2024年第3期14卷 106-113页

作者： Siddick Oumar Kenza Fathallah hassan ahmed Aicha Merzem Hasnaa Belgadir Omar Amriss Nadia Moussali Naima El Benna Department of Radiology University Hospital Center Ibn Rochd Casablanca Morocco

Median arcuate ligament syndrome (MALS), is a rare abdominal vascular compression syndrome caused by the compression of the proximal celiac trunk by the median arcuate ligament. According to many authors, a low insertion of the diaphragmatic crura or an abnormally high origin of the celiac trunk from the aorta can cause compression of the celiac artery. Usually, patients with MALS are asymptomatic. Computed tomography (CT) angiography of the abdomen is the main imaging modality to confirm the diagnosis. The coexistence of celiac trunk and superior mesenteric artery compression by the median arcuate ligament is rarely described in the literature. To our knowledge, until now, a simultaneous combination of three abdominal vascular compressions by the median arcuate ligament has never been described. From this case, we report a simultaneous compression of the celiac trunk, superior mesenteric artery, and renal arteries by the median arcuate ligament.

关键词： Median Arcuate Ligament Syndrome (MALS) Celiac Trunk Compression Superior Mesenteric Artery and Renal Arteries Compression Computed Tomography Angiography

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Sero-Prevalence and Risk factors of Contagious Bovine Pleuropneumonia (CBPP) in Afgoye District Lower Shabelle Region, Somalia

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Open Journal of Veterinary Medicine 2024年第2期14卷 11-20页

作者： ahmed Mohamed ahmed Sumaya hassan Ali Abdisalam Mohamed Ali Abdirazack Saleban Osman Binti Abubakar Mohamed Abdifatah Mohamud Ibar Shafii Abdullahi Mohamed Mohamed Abdelrahman Mohamed ahmed Ali Omar Zakaria Ibrahim Issack College of Veterinary Medicine Abrar University Mogadishu Somalia Faculty of Veterinary Medicine and Animal Husbandry Somali National University Mogadishu Somalia Faculty of Veterinary Science Benadir University Mogadishu Somalia

Contagious bovine Pleuropneumonia (CBPP) is an infectious and highly contagious respiratory disease of cattle and water buffalo, caused by the Mycoplasma mycoides subspecies mycoides. It induces significant economic losses and leads to a severe livestock production problem, negatively influencing people’s livelihoods of affected countries. In Somalia, there is no updated data on the prevalence and distribution of the disease. Hence, a descriptive cross-sectional study was conducted from September 2022 to June 2023 in different villages under the Afgoye District of lower Shabelle region, Somalia. The main purpose of this study is to assess the sero-prevalence and identify the associated risk factors for the occurrence of the disease. In this study, villages, age, sex, breed, and body condition were considered as risk factors. A total of 90 blood samples were collected and tested in the laboratory using the Anti-CBPP Elisa kit test. Out of 90 serum samples from herd cattle, 32 were positive, resulting in an overall prevalence of 35.5%. In addition, we found a statistically significant variation between the prevalence of the disease and factors such as sex, age, body condition and breeds. In summary, the overall prevalence of Contagious bovine pleuropneumonia in this study area is worth to be considered because there is a low quality of health care and less awareness of the Contagious bovine Pleuropneumonia effects on herds, which warrants the official authorities to act and follow appropriate preventive and control measures to reduce the incidence of the disease and generate appropriate controlling and prevention measures in all regions of Somalia.

关键词： Contagious Bovine Pleuropneumonia Sero-Prevalence Cattle Somalia Mycoplasma Cross Sectional Study

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Development of Non-ABO Red Blood Cell Alloantibodies in Patient Undergoing Allogeneic Haematopoietic Stem Cell Transplant

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Case Reports in Clinical Medicine 2024年第5期13卷 162-170页

作者： ahmed Alsuhaibani Khalid Batarfi ahmed Alharbi Haya Alwasel Abdullah Alenazi Abdulmohsen Alotaibi Jalal hassan Rayyan Alotaibi Hajer Aziz Nourah Alharethi Sara Alobaidi Maram Alonayzan Sanad Alharthi Majd Alanazi Sarah Alotaibi ahmed Shareefi Bandar Alqahtani Department of Laboratory and Pathology King Abdulaziz Medical City of National Guard Riyadh Saudi Arabia

Alloantibodies that are non ABO Alloimmunization to protein antigens happens only after exposure, in contrast to ABO isohaemagglutinins, which are present naturally, even in the absence of prior exposure. It is recognized that while non-ABO RBC antibodies are less common than ABO antibodies, they generate essentially the same issues that lead to unfavorable clinical results. If non-ABO alloantibodies are identified early on, these issues related complications may be avoided This call for an in-depth understanding of the recipient and donor’s ABO-Rh grouping, antibody screening, and the phenotype of certain antigens. Equally important, the temporal association time between transplantation and hemolysis can help identify the underlying mechanism of hemolysis and direct appropriate management. Therefore, for that, it is crucial to identify the etiology of post-HSCT anemia for prevention and therapy, in addition to a thorough grasp of the mechanism of anemia in non-ABO-incompatible HSCT and the temporal link between HSCT and anemia. Finding the cause of post-HSCT anemia is essential for prevention and therapy, in addition to a thorough grasp of the mechanism of anemia in non-ABO-incompatible HSCT and the temporal link between HSCT and anemia. Therefore, for that, it is crucial to identify the etiology of post-HSCT anemia. In this case report review, we would like to highlight the vital role of transfusion medicine services and stem cell clinical teams in paying particular attention to the clinical significance of non-ABO alloantibodies involved to avoid causing overt hemolysis of incompatible donor RBCs or delayed erythropoiesis. Considering the fact that some of the Haematopoietic stem cell transplant centers do not give an attention to the other non-ABO RBC antigens.

关键词： Haematopoietic Stem Cell Transplant (HSCT) Non-ABO Red Blood Cell Antibodies Alloantibodies

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阿拉伯国家绿色经济:发展、困境与中国角色

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阿拉伯世界研究 2024年第3期 31-70,158页

作者：王佳 [埃及]艾哈迈德·哈桑湖南师范大学外国语学院长沙410081

进入21世纪后,绿色经济成为国际社会的主流话题,多个阿拉伯国家相继提出了绿色经济转型的战略目标。阿拉伯国家绿色转型过程中的决定因素主要由其作用主体、金融投资、绿色科技及绿色理念构成。在这些因素的主导下,近年来多个阿拉伯国... 详细信息

进入21世纪后,绿色经济成为国际社会的主流话题,多个阿拉伯国家相继提出了绿色经济转型的战略目标。阿拉伯国家绿色转型过程中的决定因素主要由其作用主体、金融投资、绿色科技及绿色理念构成。在这些因素的主导下,近年来多个阿拉伯国家在绿色经济发展上取得了长足进展,但也面临着转型困境,需要解决国家优先事项议程、产业平衡及中小企业发展滞后、技术转让需求增加和技术创新能力不济、可持续发展财政拨款和社会融资贫乏等问题。中国在阿拉伯国家绿色转型过程中扮演了重要角色,其绿色经济发展的经验与策略为阿拉伯国家提供了较好的示范作用,主要体现在战略应和、技术转移、对外投资和智库交流四个方面。伴随阿拉伯国家绿色经济转型的不断深入,中国与阿拉伯国家在该领域的合作也呈现出前所未有的机遇。

关键词：阿拉伯国家绿色经济转型中国角色绿色发展

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Mental Health Consequences among Sudanese Due to the Armed Conflicts and Civil Unrest of 2023: One Year Later

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Journal of Biosciences and Medicines 2024年第4期12卷 21-37页

作者： Sahar Moawia Balla Elnour Nahla Yousif Osman Mohammed Saeed Awadia Babiker Mohammed Osman Abeer Alawad hassan Eman Mohamed Nour Hamad Alneel Mustafa Rowa Abdelmonem Sidig Hamato Malaz Mohamed Khair Alsafi Mohamed Amna Alnaim Mohamed ahmed Osman Awab Abdelbagi Mustafa ahmed Jalal Abdelrasool hassan Eltaib Department of Family Medicine Health Gates Riyadh Saudi Arabia Family Medicine Department Ultracare Home Health Care Riyadh Saudi Arabia Psychiatic Department Erada Hospital and Mental Health Alkharj Saudi Arabia Family Medicine Department Ahmed Gasim Diabetic Center Portsudan Sudan QCHP Qatar Qatar Primary Care Najran Health Cluster Najran Saudi Arabia Emergency Department Best Care Hospital Khartoum Sudan Family Medicine Department Mouwasat Hospital Khobar Saudi Arabia

Aim: To investigate depression, anxiety, PTSD, and insomnia levels among Sudanese citizens after a year has passed since the start of Armed Forces conflict in Sudan. Methods: An online survey was distributed. It is composed of five parts, covering the following areas: 1) sociodemographic data;2) depression assessment;3) generalized anxiety disorder assessment;4) post-traumatic stress disorder assessment;and 5) insomnia assessment. Statistical Package for Social Sciences version 27 was used for data analysis;frequency and percentage were used to describe the qualitative variables. Spearman’s correlation analysis and Chi-square test were used for correlation and association analysis;a P-value equal to or less than 0.05 was considered statistically significant. Results: The study included 283 participants, primarily female (76.0%), with a mean age of 35.26 ± 6.96 years. The majority of participants were married (50.5%) and had a university level of education (50.2%). At the start of the war, 70.3% of participants were inside the war zones, and at the time of data collection, 73.5% were outside Sudan. The length of stay in the war zone ranged from 1 to 300 days, with a mean of 48.59 ± 70.284 days. Additionally, 63.3% of participants stated that they did not receive any form of mental health intervention, and the remaining did not provide an answer. There was a high prevalence of moderate-severe depression (50.5%), moderate anxiety (35.3%), PTSD (56.5%), and sub-threshold insomnia (53.4%) among the participants. Correlation analyses revealed associations between demographic factors such as sex, age, marital status, and education and mental health issues. Notably, female participants showed a higher prevalence of PTSD (53.0%) compared to male participants (67.6%). Conclusions: There is a substantial impact of war-related trauma on mental health, revealing a high prevalence of moderate-severe depression, moderate anxiety, PTSD, and sub-threshold insomnia among the particip

关键词： Sudan War Conflict Mental Health

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