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Long non-coding RNA(lncRNA):A potential therapeutic target in acute lung injury

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Genes & Diseases 2022年第5期9卷 1258-1268页

作者： Almaz Zaki M.Shadab ali Vijay Hadda syed Mansoor ali Anita Chopra Tasneem Fatma Department of Pulmonary Critical Care and Sleep MedicineAll India Institute of Medical SciencesNew Delhi 110029India Department of Biosciences Jamia Millia Islamia UniversityNew Delhi 110025India Department of Biotechnology Jamia Millia Islamia UniversityNew Delhi 110025India Lab Oncology Dr.BRA-IRCHAll India Institute of Medical SciencesNew Delhi 110029India

Acute Lung Injury(ali)and its severe form Acute Respiratory Distress Syndrome(ARDS)are the major cause of ICU death ***/ARDS is characterized by severe hypoxemia and inflammation that leads to poor lung *** many advances in understanding and management,ali/ARDS is still causing significant morbidity and *** non-coding RNA(lncRNA)is a fast-growing topic in lung inflammation and *** is a class of non-coding RNA having a length of more than 200 *** has been a center of research for understanding the pathophysiology of various diseases in the past few *** studies have shown that lncRNAs are abundant in acute lung injury/injuries in mouse models and cell *** targeting these long non-coding RNAs,many investigators have demonstrated the alleviation of ali in various mouse ***,lncRNAs show great promise as a therapeutic target in *** review provides the current state of knowledge about the relationship between lncRNAs in various biological processes in acute lung injury and its use as a potential therapeutic target.

关键词： Acute lung injury Apoptosis Inflammation Long non-coding RNA(lncRNA) Macrophage polarization

Unicast routing protocols for urban vehicular networks:review, taxonomy, and open research issues

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Journal of Zhejiang University-Science C(Computers and Electronics) 2014年第7期15卷 489-513页

作者： syed Adeel ali SHAH Muhammad SHIRAZ Mostofa Kamal NASIR Rafidah Binti MD NOOR Mobile Ad Hoc Technology Lab Faculty of Computer Science and Information TechnologyUniversity of Malaya

Over the past few years, numerous traffic safety applications have been developed using vehicular ad hoc networks(VANETs). These applications represent public interest and require network-wide dissemination techniques. On the other hand, certain non-safety applications do not require network-wide dissemination *** applications can be characterized by their individual interest between two vehicles that are geographically apart. In the existing literature, several proposals of unicast protocols exist that can be used for these non-safety applications. Among the proposals, unicast protocols for city scenarios are considered to be most *** implies that in city scenarios unicast protocols show minimal persistence towards highly dynamic vehicular characteristics, including mobility, road structure, and physical environment. Unlike other studies, this review is motivated by the diversity of vehicular characteristics and difficulty of unicast protocol adaption in city *** review starts with the categorization of unicast protocols for city scenarios according to their requirement for a predefined unicast path. Then, properties of typical city roads are discussed, which helps to explore limitations in efficient unicast communication. Through an exhaustive literature review, we propose a thematic taxonomy based on different aspects of unicast protocol operation. It is followed by a review of selected unicast protocols for city scenarios that reveal their fundamental characteristics. Several significant parameters from the taxonomy are used to qualitatively compare the reviewed protocols. Qualitative comparison also includes critical investigation of distinct approaches taken by researchers in experimental protocol evaluation. As an outcome of this review, we point out open research issues in unicast routing.

关键词： Unicast protocols Taxonomy Protocol review Vehicular ad hoc networks Geographic routing

Effect of Salicylic Acid on Salinity-induced Changes in Brassica juncea

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Journal of Integrative Plant Biology 2008年第9期50卷 1096-1102页

作者： Mohammad Yusuf syed Aiman Hasan Barket ali Shamsul Hayat Qazi Fariduddin Aqil Ahmad Plant Physiology Section Department of Botany Aligarh Muslim University Department of Applied Sciences Higher College of Technology

Seeds of Indian mustard （Brassicajuncea （L.） Czern. et Coss.） were exposed to 0, 50, 100 and 150 mmol/L NaCI for 8 h and seeds were sown in an earthen pot. These stressed seedlings were subsequently sprayed with 10μmol/L salicylic acid （SA） at 30 d and were sampled at 60 d to assess the changes in growth, photosynthesis and antioxidant enzymes. The seedlings raised from the seeds treated with NaCI had significantly reduced growth and the activities of carbonic anhydrase, nitrate reductase and photosynthesis, and the decrease was proportional to the increase in NaCI concentration. However, the antioxidant enzymes （catalase, peroxidase and superoxide dismutase） and proline content was enhanced in response to NaCI and/or SA treatment, where their interaction had an additive effect. Moreover, the toxic effects generated by the lower concentration of NaCI （50 mmol/L） were completely overcome by the application of SA. It was, therefore, concluded that SA ameliorated the stress generated by NaCl through the alleviated antioxidant system.

关键词： carbonic anhydrase catalase mustard net photosynthetic rate nitrate reductase peroxidase salicylic acid salinity superoxidedismutase.

Edge-Computing with Graph Computation:A Novel Mechanism to Handle Network Intrusion and Address Spoofing in SDN

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Computers, Materials & Continua 2020年第12期65卷 1869-1890页

作者： Rashid Amin Mudassar Hussain Mohammed Alhameed syed Mohsan Raza Fathe Jeribi ali Tahir University of Engineering and Technology TaxilaPakistan University of Wah Wah CanttPakistan Jazan University JazanSaudi Arabia Abasyn University Islamabad IslamabadPakistan

Software Defined Networking(SDN)being an emerging network control model is widely recognized as a control and management *** model provides efficient techniques to control and manage the enterprise *** emerging paradigm is edge computing in which data processing is performed at the edges of the network instead of a central *** data processing at the edge nodes reduces the latency and bandwidth *** SDN,the controller is a single point of *** security issues related to the traditional network can be solved by using SDN central management and *** Spoofing and Network Intrusion are the most common *** attacks severely degrade performance and *** propose an edge computing-based mechanism that automatically detects and mitigates those *** this mechanism,an edge system gets the network topology from the controller and the Address Resolution Protocol(ARP)traffic is directed to it for further *** such,the controller is saved from unnecessary processing related to addressing *** propose a graph computation based method to identify the location of an attacker or intruder by implementing a graph difference *** using the correct location information,the exact attacker or intruder is blocked,while the legitimate users get access to the network *** proposed mechanism is evaluated in a Mininet simulator and a POX *** results show that it improves system performance in terms of attack mitigation time,attack detection time,and bandwidth requirements.

关键词： Software Defined Networking(SDN) edge computing Address Resolution Protocol(ARP) ARP inspection security graph difference

Angular velocity dynamics identification of small unmanned helicopter using fuzzy model

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Journal of Beijing Institute of Technology 2014年第4期23卷 527-533页

作者： KHIZER Arbab Nighat 戴亚平 syed Amjad ali 许向阳 School of Automation Beijing Institute of Technology Mehran University of Engineering and Technology JamshoroSindhPakistan School of Mechatronics Beijing Institute of Technology

Attitude identification method for unmanned helicopter based on fuzzy model at hovering is presented. The dynamical attitude model is considered as basis for attitude control and it is very complex. To reduce the complexity of model, nonlinear model of unmanned helicopter with unknown parameters are to be determined by fuzzy system first and then derivative based gradient method is used to identify unknown parameters of model. Gradient method is used due to ability that fuzzy system is not necessarily to be linear in parameters, therefore all fuzzy sets for input and output can be adjusted. The validity of the proposed model was verified using experimental data obtained by the commercially available flight simulator X-Plane. The simulation results showed high accuracy of the modeling method and attitude dynamics data matched well with experimental data.

关键词： small unmanned helicopter ( SUH ) identification Takagi-Sugeno ( TS ) fuzzy model attitude model gradient method

Thickness-dependent monochalcogenide GeSe-based CBRAM for memory and artificial electronic synapses

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Nano Research 2022年第3期15卷 2263-2277页

作者： Asif ali Haider Abbas Muhammad Hussain syed Hassan Abbas Jaffery Sajjad Hussain Changhwan Choi Jongwan Jung HMC(Hybrid Materials Center)and Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 143–747Republic of Korea Division of Materials Science and Engineering Hanyang UniversitySeoul 04763Republic of Korea

Investigating the promising chalcogenide materials for the development of memory and advanced neuromorphic computing applications is a critical step in realizing electronic memory and synaptic devices that can efficiently emulate biological synaptic ***,the assessment of monochalcogenide materials for the fabrication of highly scalable memory and electronic synaptic devices that can accurately mimic synaptic functions remain *** the present study,we investigated the thickness-dependent resistive switching(RS)behavior of conductive bridge random access memory(CBRAM)based on a monochalcogenide GeSe switching medium for its possible application in high-performance memory and electronic *** thin films of different thicknesses(6,13,24,35,47,and 56 nm)were deposited via sputtering to fabricate CBRAM devices with a stacking sequence of Ag/GeSe/Pt/Ti/SiO_(2).The devices exhibited compliance current(CC)-free and electroforming-free RS with highly stable endurance and retention characteristics with no major *** devices with a thickness of 6 nm had a low-resistance state(LRS),which required an initial reset to ensure reliable switching *** devices with a thickness of 47 nm and above exhibited the co-existence of unipolar resistive switching(U-RS)and bipolar resistive switching(B-RS)with the CC-controlled transition between the two switching *** resistance states in the 24-nm device between a high-resistance state(HRS)and an LRS were achieved by controlling the set-CC(from 5 mA to CC-free)and the reset stop voltage(from–0.5 to–1.0 V)during the set and reset processes,*** analog RS behavior of the device was further investigated with appropriate pulse measurements to emulate vital synaptic functions,including long-term potentiation(LTP),long-term depression(LTD),spike-rate-dependent plasticity(SRDP),spike-timing-dependent plasticity(STDP),paired-pulse facilitation(PPF),paired-pulse depression(PPD)and

关键词： conductive bridge random access memory(CBRAM) resistive memory switching monochalcogenide material bipolar and unipolar resistive switching multilevel resistive switching electronic synapses

On the Constant Metric Dimension of Generalized Petersen Graphs P(n,4)

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Acta Mathematica Sinica,English Series 2014年第7期30卷 1145-1160页

作者： Saba NAZ Muhammad SALMAN Usman ali Imran JAVAID syed Ahtsham-ul-Haq BOKHARY Center for Advanced Studies in Pure and Applied Mathematics Bahauddin Zakariya University

In this paper, we consider the family of generalized Petersen graphs P（n,4）. We prove that the metric dimension of P（n, 4） is 3 when n = 0 （mod 4）, and is 4 when n = 4k ＋ 3 （k is even）.For n = 1,2 （mod 4） and n = 4k ＋ 3 （k is odd）, we prove that the metric dimension of P（n,4） is bounded above by 4. This shows that each graph of the family of generalized Petersen graphs P（n, 4） has constant metric dimension.

关键词： Metric dimension constant metric dimension generalized Petersen graphs

Hard exudates referral system in eye fundus utilizing speeded up robust features

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International Journal of Ophthalmology(English edition) 2017年第7期10卷 1171-1174页

作者： syed ali Gohar Naqvi Hafiz Muhammad Faisal Zafar Ihsanul Haq International Islamic University (IIUI)

In the paper a referral system to assist the medical experts in the screening/referral of diabetic retinopathy is suggested. The system has been developed by a sequential use of different existing mathematical techniques. These techniques involve speeded up robust features（SURF）, K-means clustering and visual dictionaries（VD）. Three databases are mixed to test the working of the system when the sources are dissimilar. When experiments were performed an area under the curve（AUC） of 0.9343 was attained. The results acquired from the system are promising.

关键词： referral system speeded up robust features eye fundus visual dictionaries

Process Mining Discovery Techniques for Software Architecture Lightweight Evaluation Framework

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Computers, Materials & Continua 2023年第3期74卷 5777-5797页

作者： Mahdi Sahlabadi Ravie Chandren Muniyandi Zarina Shukur Faizan Qamar syed Hussain ali Kazmi Centre for Cyber Security Faculty of Information Science and Technology(FTSM)Universiti Kebangsaan Malaysia(UKM)Bangi43600SelangorMalaysia

This research recognizes the limitation and challenges of adaptingand applying Process Mining as a powerful tool and technique in theHypothetical Software Architecture (SA) Evaluation Framework with thefeatures and factors of lightweightness. Process mining deals with the largescalecomplexity of security and performance analysis, which are the goalsof SA evaluation frameworks. As a result of these conjectures, all ProcessMining researches in the realm of SA are thoroughly reviewed, and ninechallenges for Process Mining Adaption are recognized. Process mining isembedded in the framework and to boost the quality of the SA model forfurther analysis, the framework nominates architectural discovery algorithmsFlower, Alpha, Integer Linear Programming (ILP), Heuristic, and Inductiveand compares them vs. twelve quality criteria. Finally, the framework’s testingon three case studies approves the feasibility of applying process mining toarchitectural evaluation. The extraction of the SA model is also done by thebest model discovery algorithm, which is selected by intensive benchmarkingin this research. This research presents case studies of SA in service-oriented,Pipe and Filter, and component-based styles, modeled and simulated byHierarchical Colored Petri Net techniques based on the cases’ *** this framework dealswith the system’s log files obtainedfrom SA simulation. Applying process mining is challenging, especially for aSA evaluation framework, as it has not been done yet. The research recognizesthe problems of process mining adaption to a hypothetical lightweightSA evaluation framework and addresses these problems during the solutiondevelopment.

关键词： Software architecture process mining hierarchical colored petri Net architectural discovery algorithms model discovery algorithm