检索结果-南通市图书馆

American Journal of Plant Sciences 2016年第3期7卷 437-445页

作者： swati rawat Geeta Joshi D. Annapurna A. N. Arunkumar Nataraja N. Karaba Tree Improvement and Genetics Division Institute of Wood Science and Technology Bengaluru India Department of Crop Physiology University of Agricultural Sciences GKVK Bengaluru India

Melia dubia Cav. of family Meliaceae is a fast growing, high value tree species native to India. Isolating DNA from matured dried leaves of M. dubia was difficult due to accumulation of secondary metabolites, majorly polyphenolics, which resulted in dark brown to black colour of the pellet. In this study, a modified STE-(Sucrose, Tris-HCl and Ethylene Diamine Tetra Acetic Acid) CTAB (hexadecyltrimethylammonium bromide) method was standardized for removal of polyphenolics. The protocol developed yielded 200 - 1000 ng/μl of quality DNA without any impurities as evident by A260/280 ratio ranging from 1.75 - 2.0. It was also suitable for extracting quality DNA from other members of Meliaceae like Azadirachta indica and Melia azedarach. In downstream applications, the extracted DNA was used for PCR amplification by using ISSR and SSR markers. ISSR PCR conditions were optimized in a reaction volume of 25 μl, consisting of 30 ng of template DNA, 1.5 mM MgCl2, 200 μM of each of dNTPs and 2 U of Taq polymerase. The best amplification was observed and the same was applicable for SSR markers.

关键词： DNA Extraction Downstream Applications ISSR Mature Dried Leaves Melia dubia SSR

Numerical analysis of moving train induced vibrations on tunnel,surrounding ground and structure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2024年第1期23卷 179-192页

作者： swati Srivastav Sowmiya Chawla Swapnil Mishra Department of Applied Geophysics Indian Institute of Technology(ISM)Dhanbad 826004India Department of Civil Engineering Indian Institute of Technology(ISM)Dhanbad 826004India Department of Mining Engineering Indian Institute of Technology(ISM)Dhanbad 826004India

This study is focused on the effect of vibration induced by moving trains in tunnels on the surrounding ground and structures.A three-dimensional finite element model is established for a one-track railway tunnel and an adjacent twelve-storey building frame by using commercial software Midas GTS-NX(2019)and Midas *** study considered the moving load effect of a complete train,which varies with space as well as with *** effect of factors such as train speed,overburden pressure on the tunnel and variation in soil properties are studied in the time *** a result,the variations in horizontal and vertical acceleration for two different sites,i.e.,the free ground surface(without structure)and the area containing the structure,are ***,the displacement pattern of the raft foundation is plotted for different train *** lower speeds,the heaving phenomenon is negligible,but as the speed increases,both the heaving and differential settlement increase in the *** study demonstrates that the effect of moving train vibrations should be considered in the design of new nearby structures and proper ground improvement should be considered for existing structures.

关键词： moving train load tunnels vibration effect finite element method(FEM) wave propagation

Sirtuin 1 in regulating the p53/glutathione peroxidase 4/gasdermin D axis in acute liver failure

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第34期30卷 3850-3855页

作者： swati Katoch Vikram Patial Division of Dietetics and Nutrition Technology Institute of Himalayan Bioresource TechnologyPalampur 176061Himachal PradeshIndia Academy of Scientific and Innovative Research Ghaziabad 201002Uttar PradeshIndia

In this editorial,we comment on the article by Zhou et *** study reveals the connection between ferroptosis and pyroptosis and the effect of silent information regulator sirtuin 1(SIRT1)activation in acute liver failure(ALF).ALF is characterized by a sudden and severe liver injury resulting in significant hepatocyte damage,often posing a high risk of *** predominant form of hepatic cell death in ALF involves apoptosis,ferroptosis,autophagy,pyroptosis,and *** peroxidase 4(GPX4)inhibition sensitizes the cell to ferroptosis and triggers cell death,while Gasdermin D(GSDMD)is a mediator of *** study showed that ferroptosis and pyroptosis in ALF are regulated by blocking the p53/GPX4/GSDMD pathway,bridging the gap between the two *** inhibition of p53 elevates the levels of GPX4,reducing the levels of inflammatory and liver injury markers,ferroptotic events,and GSDMDN protein *** p53 expression and increased GPX4 on deletion of GSDMD indicated ferroptosis and pyroptosis ***1 is a NAD-dependent deacetylase,and its activation attenuates liver injury and inflammation,accompanied by reduced ferroptosis and pyroptosis-related proteins in ***1 activation also inhibits the p53/GPX4/GSDMD axis by inducing p53 acetylation,attenuating LPS/D-GalN-induced ALF.

关键词： Acute liver failure Ferroptosis Gasdermin D Pyroptosis p53 Silent information regulator sirtuin 1

Current perspective on amyloid aggregation accelerating properties of the artificial butter flavoring,diacetyl

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2024年第10期19卷 2113-2114页

作者： Ashish P.Vartak swati S.More Center for Drug Design College of PharmacyUniversity of MinnesotaMinneapolisMNUSA

The amyloid—what peptide can resist its entropic bliss?Without kinetic barricades and chaperones,most peptides would simply tumble down that *** amyloid-β(Aβ) peptides are understood to underlie the hallmark pathology of Alzheimer's disease(AD) and are considered one of the causative factors for neurodegeneration and cognitive *** affects critical connected structures within the brain that are responsible for memory,language,and social behavior.

关键词： amyloid Alzheimer Aβ

Reply to comment on “Ferroelectric composite-based piezoelectric energy harvester for self-powered detection of obstructive sleep” by A. Tkach and O. Okhay

在线全文

学校读者我要写书评

暂无评论

Journal of Materiomics 2024年第5期10卷 1160-1164页

作者： swati Panda Hyoju Shin Sugato Hajra Yumi Oh Wonjeong Oh Jeonghyeon Lee P.M.Rajaitha Basanta Kumar Panigrahi Jyoti Shukla Alok Kumar Sahu Perumal Alagarsamy Hoe Joon Kim Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988South Korea Department of Electrical Engineering Siksha‘O’Anusandhan UniversityBhubaneswar 751030India Department of Electrical Engineering Poornima College of EngineeringJaipur 303903India Department of Physics Indian Institute of Technology-GuwahatiAssam 781039India Robotics and Mechatronics Research Center Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988South Korea

In this contribution,we reply to comments made by Tkach et *** our publication *** 2023;9:*** main interest of our work is to synthesize a lead-free material,SrTi_(2)O_(5)(STO),and then utilize it in the formation of composites and finally design the piezoelectric nanogenerator(PENG)for self-powered sensor *** authors have observed the presence of piezoelectric voltage and current output from the *** authors humbly indicate that the PENG devices were poled using a DC poling setup as conditions mentioned in *** 2023;9:609(Panda et al.,2023)[1].The doping of STO into the PDMS increased from 2% to 20%(in mass).In this process,the piezoelectric output of the PENG device was observed to be highest for 15%(in mass)STO-PDMS ***,we agree with the comment raised by Tkach et al.,and further we have addressed the issues in a step-by-step response as follows.

关键词： Ferroelectric Lead-free Piezoelectric Polycrystalline

Decoding bovine coronavirus immune targets:an epitope informatics approach

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Diseases 2024年第2期4卷 138-153页

作者： swati Rani Mehnaj Khatoon Jagadish Hiremath Kuralayanapalya Puttahonnappa Suresh Jayashree Anandakumar Nagendra Nath Barman Sheethal Manjunath Yamini Sri S Sharanagouda S.Patil Spatial Epidemiology Lab ICAR-National Institute of Veterinary Epidemiology and Disease InformaticsYelahankaBengaluruKarnataka 560064India College of Veterinary Science Assam Agricultural UniversityGuwahatiAssam 785013India Yuvaraja’s College Mysuru University of MysuruMysuruKarnataka 570005India

Bovine coronavirus(BCoV)poses a significant threat to the global cattle industry,causing both respiratory and gastrointestinal infections in cattle *** necessitates the development of efficacious *** several inactivated and live BCoV vaccines exist,they are predominantly limited to *** immunization of adult cattle is imperative for BCoV infection control,as it curtails viral transmission to calves and ameliorates the impact of enteric and respiratory ailments across all age groups within the *** study presents an in silico methodology for devising a multiepitope vaccine targeting *** spike glycoprotein(S)and nucleocapsid(N)proteins,which are integral elements of the BCoV structure,play pivotal roles in the viral infection cycle and immune *** constructed a remarkably effective multiepitope vaccine candidate specifically designed to combat the BCoV *** immunoinformatics technology,B-cell and T-cell epitopes were predicted and linked together using linkers and adjuvants to efficiently trigger both cellular and humoral immune responses in *** in silico construct was characterized,and assessment of its physicochemical properties revealed the formation of a stable vaccine *** 3D modeling of the vaccine construct,molecular docking revealed a stable interaction with the bovine receptor ***,the viability of the vaccine’s high expression and simple purification was demonstrated by codon optimization and in silico cloning expression into the pET28a(+)*** applying immunoinformatics approaches,researchers aim to better understand the immune response to bovine coronavirus,discover potential targets for intervention,and facilitate the development of diagnostic tools and vaccines to mitigate the impact of this virus on cattle health and the livestock *** anticipate that the design will be useful as a preventive treatment for BCoV sickness in cattle,opening the door for furthe

关键词： Immunoinformatics Bovine coronavirus Multiepitope vaccine Molecular docking In silico cloning

Rice-wheat comparative genomics:Gains and gaps

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Crop Journal 2024年第3期12卷 656-669页

作者： Akila Wijerathna-Yapa Ruchi Bishnoi Buddhini Ranawaka Manu Maya Magar Hafeez Ur Rehman swati G.Bharad Michal T.Lorenc Vinita Ramtekey Sasha Gohar Charu Lata Md.Harun-Or-Rashid Maryam Razzaq Muhammad Sajjad Bhoja *** School of Agriculture and Food Sustainability The University of QueenslandSt LuciaQLD 4072Australia ARC Centre of Excellence for Plant Success in Nature and Agriculture The University of QueenslandSt LuciaQLD 4072Australia Department of Genetics and Plant Breeding College of AgricultureUmmedganj-KotaAgriculture UniversityKotaRajasthan 324001India Centre for Agriculture and the Bioeconomy Queensland University of Technology(QUT)2 George StreetBrisbaneQLD 4000Australia UWA School of Agriculture and Environment The University of Western Australia35 Stirling HighwayCrawleyWA 6009Australia Nepal Agriculture Research Council KhumaltarLalitpurNepal Department of Agronomy University of AgricultureFaisalabad 38040Pakistan Department of Agricultural Botany Dr Panjabrao Deshmukh Krishi VidyapeethAkola 444104MaharashtraIndia ICAR-Indian Institute of Seed Science MauUttar Pradesh 275103India School of Natural Sciences Macquarie UniversityMacquarie ParkNSW 2109Australia ICAR-Indian Institute of Wheat and Barley Research Flowrdale 54642ShimlaIndia International Maize and Wheat Improvement Center(CIMMYT)Bangladesh Office Gulshan-2Dhaka 1212Bangladesh Center for Seed Science University of AgricultureFaisalabad 38000Pakistan Department of Biosciences COMSATS University IslamabadPark RoadTarlai KalanIslamabad 45550Pakistan CGIAR’s Excellence in Breeding(EiB)Platform/Accelerated Breeding Initiative International Maize and Wheat Improvement Center(CIMMYT)El Batán 56237Mexico

Rice and wheat provide nearly 40%of human calorie and protein *** share a common ancestor and belong to the Poaceae(grass)*** their genetic homology is crucial for developing new cultivars with enhanced *** wheat genes and gene families have been characterized based on their rice ***–wheat orthology can identify genetic regions that regulate similar traits in both ***–wheat comparative genomics can identify candidate wheat genes in a genomic region identified by association or QTL mapping,deduce their putative functions and biochemical pathways,and develop molecular markers for marker-assisted breeding.A knowledge of gene homology facilitates the transfer between crops of genes or genomic regions associated with desirable traits by genetic engineering,gene editing,or wide crossing.

关键词： Comparative genomics Orthologs Genes Synteny Genetic engineering Molecular breeding

The potential role of essential oils in boosting immunity and easing COVID-19 symptoms

在线全文

学校读者我要写书评

暂无评论

Clinical Traditional Medicine and Pharmacology 2024年第2期5卷 54-62页

作者： Vivek P Chavda Pankti C.Balar Gargi Jogi swati Marwadi Aayushi Patel Avani Doshi Jinal Ajabiya Lalitkumar Vora Department of Pharmaceutics and Pharmaceutical Technology L.M.College of PharmacyAhmedabad 380009GujaratIndia Department of Biotechnology Savitribai Phule University of Pune411041MaharashtraIndia Pharmacy Section Long Island UniversityUniversity PlazaBrooklynNY 11201United States Department of Pharmaceutical Chemistry K B Raval College of PharmacyGandhinagar 382423India Department of Pharmaceutics Analysis National Institute of Pharmaceutical Education and Research(NIPER)Ahmedabad 380009GujaratIndia School of Pharmacy Queen’s University Belfast97 Lisburn RoadBT97BLUK

Background:Several trials have been conducted since the beginning of the COVID-19 pandemic to establish possible clinical treatments for the infected ***,many these approaches have failed to demonstrate positive results in human clinical *** the middle of this investigation,essential oils attracted interest due to their numerous benefits and possible role in management of *** oils have virucidal effects at nontoxic quantities due to their tiny molecular size,high lipophilicity,and quick commencement of ***,the pulmonary exhalation,lower respiratory stimulus,and deep lung transport properties of essential oils increase their potential medicinal ***:The present review aimd to evaluate the potential efficacy of essential oil in management of ***:Following the Preferred Reporting Items for Systematic Review and Meta-Analysis(PRISMA)guidelines,studies published in English up to January 2024 were searched in the PubMed,Scifinder,and Scopus database,using relevant keywords,such as“Essential oil and COVID-19”,“Essential Oil and Viral Infection”,*** non-English articles,abstracts,conference papers,book chapters,and reviews were ***:A total of 108 potentially relevant articles were included for full-text review,with the emphasis is on scrutinizing the probable antiviral action of essential oils to inhibit the replication of *** tried to provide an opinion based on different studies performed using the same concept in different corners of the ***:Various essential oils hold a great potential to work as an adjuvant therapy in management and prevention of COVID-19.

关键词： COVID-19 SARS-CoV-2 Sunlight UV radiation Essential oil

Effects of thermal radiation on Casson fluid flow and heat transfer over an unsteady stretching surface subjected to suction/blowing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2013年第11期22卷 362-368页

作者： swati Mukhopadhyay Department of Mathematics The University of Burdwan

The unsteady flow of a Casson fluid and heat transfer over a stretching surface in presence of suction/blowing are investigated. The transformed equations are solved numerically by using the shooting method. The exact solution corre- sponding to the momentum equation for the steady case is obtained. Fluid velocity initially decreases with the increase of unsteadiness parameter. Due to an increasing Casson parameter the velocity field is suppressed. Thermal radiation enhances the effective thermal diffusivity and the temperature rises.

关键词： unsteady flow Casson fluid stretching surface suction/blowing

Heat Transfer in a Moving Fluid over a Moving Non-Isothermal Flat Surface

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2011年第12期28卷 183-186页

作者： swati Mukhopadhyay Department of Mathematics The University of BurdwanBurdwan-713104W.B.India

Boundary layer forced convective flow and heat transfer passing a moving flat surface parallel to a moving stream are *** power-law surface temperature of the second degree at the boundary is *** similarity solutions for the problem are obtained and the reduced ordinary differential equations are solved *** numerical results are compared with the known results from the literature for some special cases of the present study to support their *** is found that dual solutions exist when the surface and the fluid move in opposite directions.

关键词： moving ordinary directions