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An analysis of first-time and repeat visitors to Korean national parks from 2007 and 2013

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Journal of Mountain Science 2017年第12期14卷 2527-2539页

作者： yunseon choe michael a.schuett kyu-won sim department of tourism management college of hotel and tourism managementkyung hee university26Kyungheedae-roDongdaemun-guSeoul02447Republic of Korea department of recreation park and tourism sciencestexas a&m university600 John Kimbrough BirdCollege StationTex as 77843USA national park research institute korea national park serviceWonju 26441Republic of Korea

This paper examined visitors to Bukhansan National Park in Korea based on first-time and repeat visitation. Bukhansan National Park is Korea's most heavily visited national park with annual visitation of six million visitors in 2015. Data used in this article were collected on-site in the park in 2007 and 2013 by the Korea National Park Service(KNPS).The study variables included socio-demographics,travel behavior, motivation, and satisfaction with park attributes, services and facilities. Data were analyzed by each study year for first-time and repeat *** showed significant differences for both firsttime and repeat visitors on several socio-demographic,travel behavior, and motivation variables within each study year. For satisfaction with park attributes,facilities and services, first-time visitors were significantly different from repeat visitors on seven variables for both years. Implications are given regarding programs and services to improve visitor satisfaction and sustain the natural, cultural and historical resources at Bukhansan National Park and other national parks in Korea. Future research suggestions are provided to learn more about visitor characteristics, standards of quality and preferences in the national parks.

关键词： Bukhansan National Park Korean national parks Visitor behaviour Market segmentation Visitor satisfaction

PI3K/Akt/mTOR inhibitors in breast cancer

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Cancer Biology & Medicine 2015年第4期12卷 342-354页

作者： Joycelyn JX Lee Kiley Loh Yoon-sim Yap Department of Medical Oncology National Cancer Center Singapore

Activation of the phosphoinositide 3 kinase(PI3K)/Akt/mammalian target of rapamycin(mTOR) pathway is common in breast cancer. There is preclinical data to support inhibition of the pathway, and phase Ⅰ to Ⅲ trials involving inhibitors of the pathway have been or are being conducted in solid tumors and breast cancer. Everolimus, an mTOR inhibitor, is currently approved for the treatment of hormone receptor(HR)-positive, human epidermal growth factor receptor 2(HER2)-negative breast cancer. In this review, we summarise the efficacy and toxicity findings from the randomised clinical trials, with simplified guidelines on the management of potential adverse effects. Education of healthcare professionals and patients is critical for safety and compliance. While there is some clinical evidence of activity of mTOR inhibition in HR-positive and HER2-positive breast cancers, the benefits may be more pronounced in selected subsets rather than in the overall population. Further development of predictive biomarkers will be useful in the selection of patients who will benefit from inhibition of the PI3K/Akt/mTOR(PAM) pathway.

关键词： Breast cancer phosphoinositide 3 kinase(PI3K)/Akt/ mammalian target of rapamycin(mTOR) everolimus

Post-disaster Psychosocial Capacity Building for Women in a Chinese Rural Village

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International Journal of Disaster Risk Science 2019年第2期10卷 193-203页

作者： Timothy sim Jocelyn Lau Ke Cui Hsi-Hsien Wei Department of Applied Social Sciences The Hong KongPolytechnic UniversityHong KongChina World Health Organization Collaborating Centre forCommunity Health Services School of NursingThe HongKong Polytechnic UniversityHong KongChina School of Public Administration Sichuan UniversityChengdu610065China Department of Building and Real Estate The Hong KongPolytechnic UniversityHong KongChina

Mental health interventions following disasters have been criticized as individualistic, incomplete, and culturally insensitive. This article showcases the effects of a culturally relevant and sustainable psychosocial capacitybuilding project at the epicenter of the 2008 Wenchuan Earthquake. Specifically, the project focuses on women, a group that has received limited attention in post-disaster recovery in China. This qualitative research study(N = 14)sheds light on the characteristics and processes of the implementation of a post-disaster psychosocial intervention project in rural China. In addition, by adopting the Success Case Method as an evaluation approach, this study elucidates its effects on the psychological and social changes of the disaster victims. The findings capture five aspects of psychosocial changes: enriched daily life, better mood,enhanced self-confidence, increased willingness to socialize, and the provision of mutual help. This study hopes to encourage more culturally relevant and empowering practices for women in building their psychosocial capacity after disasters.

关键词： China Natural hazard-induced disasters Post-disaster recovery Psychosocial capacity building Success case method Women’ empowerment

Plant micro-reserves in Valencia(E. Spain):A model to preserve threatened flora in China?

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Plant Diversity 2017年第6期39卷 383-389页

作者： simón Fos Emilio Laguna Juan Jimenez Miguel Angel Gómez-Serrano VAERSA-Generalitat Valenciana Avda. Corts Valencianes Servicio de Vida Silvestre Generalitat Valenciana C./ Castan Tobenas Centro para la Experimentación e Investigación Forestal (CIEF) Generalitat Valenciana Avda. Comarques del País Valencia

The Valencian Community(eastern Spain) was the pioneer territory establishing plant micro-reserves(PMRs). Its model to protect small sites for endemic and endangered plants has been exported to several countries around the globe. This paper highlights 1) the role of PMRs to complement the protection provided by large protected areas, 2) how the establishment of PMRs fosters the increase of floristic knowledge, and 3)the fact that continuous monitoring of PMRs also yields new records of endangered species found within the same PMRs. The flexibility of the PMR approach-it can be adapted to other national and regional legislationsallows its transfer to other rich-biodiversity regions and countries such as China.

关键词： Plant micro-reserves in situ conservation Threatened species Endemic plants Protected areas

Biomass seaweed-derived n itrogen self-doped porous carb on anodes for sodium-ion batteries:Insights into the structure and electrochemical activity

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Journal of Energy Chemistry 2022年第1期31卷 286-295,I0008页

作者： Chenrayan Senthil Jae Woo Park Nitheesha Shaji Gyu Sang sim Chang Woo Lee Department of Chemical Engineering(Integrated Engineering)&Center for the SMART Energy Platform College of EngineeringKyung Hee University1732 Deogyeong-daeroCihuengYonginGyeonggi 17104South Korea

Sustainable transformation and efficient utilization of biomasses and their derived materials are environ-mentally as well as economically compliant *** seaweed-derived nitrogen self-doped porous carbon with tailored surface area and pore structures are prepared through carb on izatio n and *** in fluence of carb on ization temperature on morphology,surface area,and heteroatom dopants are investigated to optimize sodium-ion storage ***-derived nitrogen selfdoped activated carbon(SAC)as anode materials for sodium-ion batteries exhibits remarkable reversible capacity of 303/192 mAh g^(-1) after 100/500 cycles at current densities of 100/200 mA g^(-1) respectively,and a good rate *** interconnected and porous conducting nature along with the heteroatom dopant role in creating defective sites and charge stabilization are favorable for ion storage and diffusion and electron transport,indicating the electrodes can offer improved electrochemical *** addition,post-mortem analysis of the cycled carbon electrodes through ex-situ tools demonstrates the sodium-ion storage mechanism.

关键词： Biomass Heteroatom self-doping Porous carbon Anode Sodium-ion batteries Post-mortem ex-situ analysis

Obtaining 2D Soil Geotechnical Profiles from Cokriging Interpolation of Sample Data and Electrical Resistivity Tomography (ERT)—Applications in Mass Movements Studies

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International Journal of Geosciences 2024年第7期15卷 525-548页

作者： Cassiano Antonio Bortolozo Noel Howley Andy Legg Tristan Pryer Danielle Silva de Paula Tatiana Sussel Gonçalves Mendes Daniel Metodiev Marcio Roberto Magalhães de Andrade Silvio Jorge Coelho simões Maiconn Vinicius de Moraes Marcio Augusto Ernesto de Moraes Luana Albertani Pampuch Rodolfo Moreda Mendes Harideva Marturano Egas Institute of Science and Technology So Paulo State University (UNESP) So Jos dos Campos Brazil Cemaden-National Center for Monitoring and Early Warning of Natural Disasters General Coordination of Research and Development So Jos dos Campos Brazil Institute for Mathematical Innovation University of Bath Bath UK Department of Mathematical Sciences University of Bath Bath UK

Brazil annually faces significant challenges with mass movements, particularly in areas with poorly constructed housing, inadequate engineering, and lacking sanitation infrastructure. Campos do Jordão, in São Paulo state, is a city currently grappling with these issues. This paper details a study conducted within a pilot area in Campos do Jordão, where geophysical surveys and geotechnical borehole data were integrated. The geophysical surveys provided 2D profiles, and samples were collected to analyse soil moisture and plasticity. These datasets were combined using a Cokriging-based model to produce an accurate representation of the subsurface conditions. The enhanced modelling of subsurface variability facilitates a deeper understanding of soil behavior, which can be used to improve landslide risk assessments. This approach is innovative, particularly within the international context where similar studies often do not address the complexities associated with urban planning deficits such as those observed in some areas of Brazil. These conditions, including the lack of proper sanitation and irregular housing, significantly influence the geological stability of the region, adding layers of complexity to subsurface assessments. Adapting geotechnical evaluation methods to local challenges offers the potential to increase the efficacy and relevance of geological risk management in regions with similar socio-economic and urban characteristics.

关键词： Mass Movements Geophysics ERT Geotechnical Surveys Campos do Jordão Cokriging

A comparative study of interface reconstruction algorithms in molten metal flow

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China Foundry 2013年第1期10卷 50-56页

作者： Young-sim Choi Jun-Ho Hong Ho-Young Hwang e-Design Center Korea Institute of Industrial TechnologyIncheon 406-840Korea

In the present research,two numerical schemes for improving the accuracy of the solution in the flow simulation of molten metal were *** method is the Piecewise Linear Interface Calculation(PLIC) method and the other is the Donor-Acceptor(D-A) *** verify the module of the interface reconstruction algorithms,simple problems were *** these validations,the accuracy and efficiency of these two methods were compared by simulating various real *** the numerical simulation of free surface flow,it is possible for the PLIC method to track very accurately the interface between *** PLIC method,however,has the weak point in that a lot of computational time is required,though it shows the more accurate interface *** Donor-Acceptor method has enough effectiveness in the macro-observation of a mold filling sequence though it shows inferior ***,for the problems that need the accurate solution,PLIC is more appropriate than *** accuracy may cause less efficiency in numerical *** method between D-A method and PLIC method should be chosen depends on the product.

关键词： interface reconstruction DA PLIC molten metal flow accuracy volume of fluid method

Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases

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Protein & Cell 2010年第8期1卷 780-790页

作者： Ali Ryan Chan-Ju Wang Nicola Laurieri Isaac Westwood Edith sim Department of Pharmacology University of OxfordMansfield RoadOxfordOX13QTUK

Azoreductases are involved in the bioremediation by bacteria of azo dyes found in waste *** the gut flora,they activate azo pro-drugs,which are used for treatment of inflammatory bowel disease,releasing the active component 5-aminosalycilic *** bacterium *** has three azoreductase genes,paAzoR1,paAzoR2 and paAzoR3,which as recombinant enzymes have been shown to have different substrate *** mechanism of azoreduction relies upon tautomerisation of the substrate to the hydrazone *** report here the characterization of the *** azoreductase enzymes,including determining their thermostability,cofactor preference and kinetic constants against a range of their favoured *** expression levels of these enzymes during growth of *** are altered by the presence of azo *** is shown that enzymes that were originally described as azoreductases,are likely to act as NADH quinone *** low sequence identities observed among NAD(P)H quinone oxidoreductase and azoreductase enzymes suggests convergent evolution.

关键词： azoreductase enzyme mechanism NAD(P)H quinone oxidoreductase enzyme characterisation convergent evolution

GSTARS computer models and their applications, Part Ⅱ: Applications

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International Journal of Sediment Research 2008年第4期23卷 299-315页

作者： Francisco J.M.sim■ES Chih Ted YANG Research Hydrologist US Geological Survey Geomorphology and Sediment Transport Laboratory4620 Technology Drive Suite 400 Golden CO 80403 USA Borland Prof. of Water Resources and Director of Hydroscience and Training Center Department of Civil and Environmental Engineering Colorado State UniversityFort Collins CO 80523-1372 USA

In part 1 of this two-paper series, a brief summary of the basic concepts and theories used in developing the Generalized Stream Tube model for Alluvial River simulation (GSTARS) computer models was presented. Part 2 provides examples that illustrate some of the capabilities of the GSTARS models and how they can be applied to solve a wide range of river and reservoir sedimentation problems. Laboratory and field case studies are used and the examples show representative applications of the earlier and of the more recent versions of GSTARS. Some of the more recent capabilities implemented in GSTARS3, one of the latest versions of the series, are also discussed here with more detail.

关键词： Computer model Reservoir River Sediment transport Unit stream power