检索结果-南通市图书馆

Structural Investigation of Cell Wall Mannan Antigen Obtained from Pathogenic Yeast Candida zeylanoides

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Medical Microbiology 2013年第2期3卷 139-143页

作者： Hidemitsu Kobayashi susumu kawakami Yukiko Ogawa Nobuyuki Shibata Shigeo Suzuki Department of Infection and Host Defense Tohoku Pharmaceutical University Sendai Miyagi Japan Laboratory of Microbiology Faculty of Pharmaceutical Science Nagasaki International University Sasebo Nagasaki Japan Sendai Research Institute for Mycology Sendai Miyagi Japan

Antigenicity of pathogenic yeast Candida zeylanoides NBRC 10326 was found to have similar to that of Candida guilliermondii, but it was slightly different, i.e. NBRC 10326 strain cells react strongly with the factor antibodies 1, 4, and 9, and react relatively weakly with factor antibody 5. We have investigated the structural characteristic of cell wall mannan of this strain using a non-degradable method, nuclear magnetic resonance analysis. The results obtained from NMR analysis, the two-dimensional homonuclear Hartmann-Hahn, indicated that C. zeylanoides mannan contains α-1, 3-linked and β-1,2-linked oligomannosyl side chains corresponding to C. guilliermondii specific antigenic factor 9. In addition, it was found that the mannan contains β-1,2-linked oligomannosyl side chains attached to phosphate groups corresponding to anitigenic factor 5, which were not found in C. guilliermondii mannan.

关键词： Candida zeylanoides Candida guilliermondii Cell Wall Mannan Antigenic Factor Nuclear Magnetic Resonance

Isolation of Mannooligosaccharides Corresponding to Antigenic Determinants of Pathogenic Yeast Candida catenulataCell Wall Mannan

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Microbiology 2013年第2期3卷 222-226页

作者： Hidemitsu Kobayashi susumu kawakami Yukiko Ogawa Nobuyuki Shibata Shigeo Suzuki Laboratory of Microbiology Faculty of Pharmaceutical Science Nagasaki International University Sasebo Nagasaki Japan

To investigate the chemical structure of cell wall mannan of pathogenic yeast, Candida catenulata IFO 0745 strain, which possess the epitopes of antigenic factors 1, 9, and 34 to genus Candida, we previously performed the two-dimensional nuclear magnetic resonance (NMR) analysis of this mannan, Fr. C, without the need for harsh procedures. In this study, three oligosaccharides, biose, triose, and tetraose, and mannose were isolated from Fr. C by acetolysis. The results of NMR analysis indicate that the chemical structures of these oligosaccharides were identified to Manα1-2Man, Manα1-2Manα1-2Man, and Manα1-3Manα1-2Manα1-2Man. The most of resultant mannose seems to be originated from the α-1,6-linked mannan backbone which is recognized by antiserum to factor 9. The inhibition assay of slide agglutination reaction between Fr. C and antigenic antibodies using three oligosaccharides indicate that the Manα1-2Manα1-2Man and Manα1-3Manα1-2Manα1-2Man possess domains corresponding to immunodominants of antigenic factors 1 and 34, respectively.

关键词： Cell Wall Mannan Antigenic Factor Candida catenulata Acetolysis Oligomannosidic Epitope

Cembrane-Type Diterpenoids and a Phenolic Compound from the Leaves of a Thai Medicinal Plant, Croton sublyratusKurz

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

American Journal of Plant Sciences 2014年第9期5卷 1370-1377页

作者： Yasue Oka susumu kawakami Sachiko Sugimoto Katsuyoshi Matsunami Hideaki Otsuka Duanporn Lhieochaiphant Sorasak Lhieochaiphant Department of Pharmaceutical Sciences Faculty of Pharmacy Chiang Mai University Chiang Mai Thailand Department of Pharmacognosy Graduate School of Bio-medical and Health Sciences Hiroshima University Hiroshima Japan Faculty of Pharmacy Payap University Chiang Mai Thailand

From the leaves of a Thai medicinal plant, Croton sublyratus, collected in Thailand, two new cembrane-type diterpenoids, named sublylactones A and B, and a phenolic compound were isolated from the EtOAc-soluble fracti... 详细信息

关键词： Croton Sublyratus Euphorbiaceae Diterpene Cembrane

Association between colonic polyps and diverticular disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第15期14卷 2411-2413页

作者： Tetsuo Hirata Yuko kawakami Nagisa Kinjo susumu Arakaki Tetsu Arakaki Akira Hokama Fukunori Kinjo Jiro Fujita Department of Medicine and Therapeutics Control and Prevention of Infectious Diseases Faculty of Medicine University of the Ryukyus Okinawa 903-0215 Japan Department of Internal Medicine Nishinjo Hospital Okinawa 900-0034 Japan Department of Endoscopy Ryukyu University Hospital Okinawa 903-0215 Japan Department of Coloproctology Nishinjo Hospital Okinawa 900-0034 Japan

AIM: To evaluate the association between colonic polyps and diverticular disease in Japan. METHODS: We retrospectively reviewed the medical records of 672 consecutive patients who underwent total colonoscopy between August 2006 and April 2007 at Nishinjo Hospital, Okinawa, Japan. Patients with a history of any of the following were excluded from the study: previous polypectomy, colonic resection, and inflammatory bowel diseases. The association between colonic polyps and diverticular disease was analyzed by logistic regression analysis, adjusted for age and sex. RESULTS: Prevalence of colonic polyps in all patients with diverticular disease was significantly higher than that in those without diverticular disease (adjusted odds ratio 1.7). CONCLUSION: Our data showed that patients with diverticular disease have a higher risk of colonic polyps compared to those without.

关键词：结肠息肉结肠赘生物憩室疾病结肠镜检查