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A FOUR -WEEK COm.ARISON OF BI-m.TOPROST 0.03% AND BIm.TOPROST 0.015% IN PATIENTS WITH ELEVATED INTRAOCULAR PRESSURE J.A. Ferreira, G.A.S.

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国际眼科杂志 2003年第1期3卷 64-64页

作者： J.A.Ferreira G.A.S.Firm. I.R.Elias S.J.Khater m.Hatanaka R.susanna-Jr. Hospital Das Clinicas da Faculdade de m.dicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP Brazil

Purpose: Intraocular Pressure (IOP) control is the m.in goal in glaucom. treatm.nt However, despite satisfactory control, the occurrence of side effects reduces com.liance. This study was designed to test if an ophtha... 详细信息

关键词： BIm.TOPROST 高眼压眼科药剂浓度 IOP

老年择期关节置换术患者术后谵妄的认知和功能预测因子及其后遗症

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麻醉与镇痛 2013年第6期9卷 13-22页

作者： Christopher J. Jankowski, m. m.x R. Trenerry, PhD David J. Cook, m. Shonie L. Buenvenida, m.q susanna R. Stevens, m. Darrell R. Schroeder, m. David O. Warner, m. 张文奇(译) 刘晓(译) 郭曲练(校) Departm.nts of Anesthesiology Psychology and Biostatistics and Departm.nt of Anesthesiology Anesthesiology Clinical Research Unit Mayo Clinic Rochester Minnesota 不详

背景术后谵妄（postoperativedelirium.POD）在老年患者中很常见，且与不良预后相关。在行择期手术的患者中，POD的认知和功能性后遗症尚且未知。我们试图研究：①在老年手术患者中，敏感性神经认知测试的较低评分能否作为POD的独立风... 详细信息

背景术后谵妄（postoperativedelirium.POD）在老年患者中很常见，且与不良预后相关。在行择期手术的患者中，POD的认知和功能性后遗症尚且未知。我们试图研究：①在老年手术患者中，敏感性神经认知测试的较低评分能否作为POD的独立风险因子；@POD能否预测手术3个月后的认知和功能下降。方法我们对年龄I〉65岁的全髋关节或全膝关节置换术患者进行了一项前瞻性队列研究。参与者接受术前的神经认知和功能测试。使用混乱评估法诊断POD。出现POD的患者组与对照组在手术后3个月接受重复的神经认知和功能测试。结果418例患者符合入选标准，有42例出现POD。各组之间在基础细微精神状态检查评分、酗酒、抑郁和语言智力等方面没有差别。POD的独立预测因子包括年龄、精神疾病史、功能状态的下降和语言记忆的下降。对于所有测试，POD患者组和匹配的对照组之／＇^-J在术前和术后3个月的变化相似。结论术前神经认知和功能状态的轻微下降可以预测POD。然而在出现POD的小群体中，没有手术后3个月出现认知和功能下降的证据。POD与术前认知功能的降低有关，但在择期手术的老年患者中，可能不存在手术后3个月有害的认知或功能后遗症。

关键词：独立预测因子全膝关节置换术老年患者神经认知择期手术术后谵妄后遗症精神状态检查

INFLUENCE OF WATER DRINKING TEST ON CENTRAL CORNEAL THICKNESS

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国际眼科杂志 2003年第1期3卷 63-63页

作者： m.Hatanaka J.A.Ferreira G.A.S.Firm. J.F.Lopes I.R.Elias C.m.rita R.susanna-Jr. Hospital Das Clinicas da Fac- uldade de m.dicina da USP BrazilHospital Das Clinicas da Fac- uldade de Medicina da USP BrazilHospital Das Clinicas da Fac- uldade de Medicina da USP BrazilHospital Das Clinicas da Fac- uldade de Medicina da USP BrazilHospital Das Clinicas da Fac- uldade de Medicina da USP BrazilHospital Das Clinicas da Fac- uldade de Medicina da USP BrazilHospital Das Clinicas da Fac- uldade de Medicina da USP Brazil

Purpose: To determ.ne if there is an influence of the Water Drinking Test (WDT) on central corneal thickness (CCT) due to the sudden change of osm.larity since an increase on CCT could lead to a false higher IOP reading on applanation tonom.try. m.thods: 38 glaucom.tous or glaucom.tous suspect patients without ocular hypotensive m.dication were subm.tted to WDT. CCT was m.asured by ultrasound pachym.try before and

关键词：饮水试验角膜中心厚度假性IDP WDT CCT

饲粮长期添加植物提取物对胴体质量和猪肉氧化稳定性特征的影响

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饲料博览 2013年第9期23卷 8-8页

作者： Raffaella R Grazia P susanna C Siria T Giuseppe m.Carlo C

在猪饲料中添加从马鞭草提取物(PE)和毛蕊花苷5 m.·kg-1,试验期从断奶到屠宰(166 d),对胴体特性、肉品质、胶原特性、抗氧化性和眼肌(LD)感官性状进行评定。每个处理取宰前活重在109.5±1.4 kg的10只猪进行屠宰。试验结果表明,PE对胴... 详细信息

在猪饲料中添加从马鞭草提取物(PE)和毛蕊花苷5 m.·kg-1,试验期从断奶到屠宰(166 d),对胴体特性、肉品质、胶原特性、抗氧化性和眼肌(LD)感官性状进行评定。每个处理取宰前活重在109.5±1.4 kg的10只猪进行屠宰。试验结果表明,PE对胴体质量、眼肌肉质量和胶原特性均无显著影响(P>0.05)。PE组眼肌的α-生育酚水平极显著升高(P<0.01),与对照组相比,PE组猪的生眼肌的脂质氧化水平极显著降低(P<0.01),试验观察到试验组的熟眼肌储存在4℃环境中24 h后脂肪的气味和酸败味强度有减弱趋势(P=0.05)。试验结果表明,PE对猪肉具有抗氧化能力,加强了氧化和感官状态,然而对于肉品质参数没有影响。

关键词：植物提取物胴体质量抗氧化性定性特征猪肉饲粮胴体特性感官性状

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由卡特琳娜和丽塔飓风引发的灾难人类学思考

民族学刊 2011年第6期2卷 36-38页

作者：苏珊娜·m.霍夫曼[美] 黄春(译) 彭文斌(校注) 旧金山大学西南民族大学四川成都610041 加拿大不列颠哥伦比亚大学亚洲研究所

新奥尔良市在2005年所遭受的卡特琳娜和丽塔飓风和水灾袭击,为美国数十年来最大的自然灾害之一。这两次飓风也唤醒了学者对灾难研究的注意力。灾难不仅冲击了社会结构,造成了不同群体聚合或边缘化,也作为一种显示器,昭示在灾难过程中最... 详细信息

新奥尔良市在2005年所遭受的卡特琳娜和丽塔飓风和水灾袭击,为美国数十年来最大的自然灾害之一。这两次飓风也唤醒了学者对灾难研究的注意力。灾难不仅冲击了社会结构,造成了不同群体聚合或边缘化,也作为一种显示器,昭示在灾难过程中最为脆弱的是穷人群体。人类学家不仅要研究灾难的影响与结果,也应该联合起来,参与救灾活动,直接为受害群体提供援助。

关键词：苏珊娜·m.霍夫曼灾难人类学社会结构灾难显示器

FAIR Principles:Interpretations and Im.lem.ntation Considerations

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Data Intelligence 2020年第1期2卷 10-29,293-302,322页

作者： Annika Jacobsen Ricardo de m.randa Azevedo Nick Juty Dom.nique Batista Sim.n Coles Ronald Cornet m.lanie Courtot m.rce Crosas m.chel Dum.ntier Chris T.Evelo Carole Goble Giancarlo Guizzardi Karsten Kryger Hansen Ali Hasnain Kristina Hettne Jaap Heringa Rob W.W.Hooft m.lanie Im.ing Keith G.Jeffery Rajaram.Kaliyaperum.l m.rtijn GKersloot Christine R.Kirkpatrick Tobias Kuhn Ignasi Labastida Barbara m.gagna Peterm.Quilton Natalie m.yers Annalisa m.ntesanti m.rjam.van Reisen Philippe Rocca-Serra Robert Pergl susanna-Assunta Sansone Luiz Olavo Bonino da Silva Santos Juliane Schneider George Strawn m.rk Thom.son Andra Waagm.ester Tobias Weigel m.rk D.Wilkinson Egon L.Willighagen Peter Wittenburg m.rco Roos Barend m.ns Erik Schultes Leiden University m.dical Center Leiden2333 ZAThe Netherlands Institute of Data Science Maastricht UniversityUniversiteitssingel 60Maastricht 6229 ERThe Netherlands Departm.nt of Com.uter Science The University of ManchesterOxford RoadManchester M139PLUK Oxford e-Research Centre Department of Engineering SciencesUniversity of OxfordOxford OX13PJUK School of Chem.stry Faculty of Engineering and Physical SciencesUniversity of SouthamptonSO171BJUK Am.terdam.Um. University of AmsterdamAmsterdam 1000 GGThe Netherlands European Bioinform.tics Institute(Em.L-EBI) HinxtonCambridgeCB101SDUK Harvard University CambridgeMassachusetts 02138USA Departm.nt of Bioinform.tics–BiGCaT NUTRIMMaastricht UniversityMaastricht 6229 ERThe Netherlands Conceptual and Cognitive m.deling Research Group(CORE) Free University of Bozen-BolzanoBolzano 39100Italy Aalborg University Aalborg DK-9220Denmark Insight Centre for Data Analytics National University of Ireland GalwayH91 TK33Ireland Centre for Digital Scholarship Leiden University LibrariesLeiden2333 ZAThe Netherlands Departm.nt of Com.uter Science Vrije Universiteit AmsterdamDe Boelelaan 11051081 HV AmsterdamThe Netherlands Dutch Techcentre for Life Sciences(DTL) UtrechtThe Netherlands SURF Utrecht 3511 EPThe Netherlands Keith G Jeffery Consultants FaringdonUK Castor EDC Paasheuvelweg 25Wing 5D1105 BPAmsterdamThe Netherlands San Diego Supercom.uter Center University of California San DiegoLa JollaCalifornia 92093USA Learning and Research Resources Centre(CRAI) Universitat de Barcelona08007 BarcelonaSpain Environm.nt Agency Austria A-1090 ViennaAustria University of Notre Dam. 75004 ParisFrance Health Research Board(HRB) Dublin 2DO2 H638Ireland Liacs Institute of Advanced Com.uter Science Leiden University2311 GJ LeidenThe Netherlands Czech Technical University in Prague Faculty of Information Technology(FIT CTU)16000 Prague 6Czech Republic GO FAIR International Support&Coordination Office(GFISCO) LeidenThe Netherlands Harvard Catalys

The FAIR principles have been widely cited,endorsed and adopted by a broad range of stakeholders since their publication in *** intention,the 15 FAIR guiding principles do not dictate specific technological im.lem.ntations,but provide guidance for im.roving Findability,Accessibility,Interoperability and Reusability of digital *** has likely contributed to the broad adoption of the FAIR principles,because individual stakeholder com.unities can im.lem.nt their own FAIR ***,it has also resulted in inconsistent interpretations that carry the risk of leading to incom.atible ***,while the FAIR principles are form.lated on a high level and m.y be interpreted and im.lem.nted in different ways,for true interoperability we need to support convergence in im.lem.ntation choices that are widely accessible and(re)-*** introduce the concept of FAIR im.lem.ntation considerations to assist accelerated global participation and convergence towards accessible,robust,widespread and consistent FAIR *** self-identified stakeholder com.unity m.y either choose to reuse solutions from.existing im.lem.ntations,or when they spot a gap,accept the challenge to create the needed solution,which,ideally,can be used again by other com.unities in the ***,we provide interpretations and im.lem.ntation considerations(choices and challenges)for each FAIR principle.

关键词： FAIR guiding principles FAIR im.lem.ntation FAIR convergence FAIR com.unities choices and challenges

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人类学者为何要研究灾难

民族学刊 2011年第4期2卷 1-7,91页

作者：安东尼·奥利弗-史密斯苏珊娜·m.霍夫曼彭文斌佛罗里达大学人类学系不详中央民族大学民族学人类学理论与方法研究中心加拿大不列颠哥伦比亚大学亚洲研究所

人类学家对灾难研究的兴趣甚早,但长期以来局限于个案的探索,缺乏理论和方法论的系统思考。安东尼·奥利弗-史密斯和苏珊娜·m.霍夫曼从人类学对灾难的定义以及相关学术动态开始讨论,涉及了与生态、物质和社会-文化联结的人类学灾难研... 详细信息

人类学家对灾难研究的兴趣甚早,但长期以来局限于个案的探索,缺乏理论和方法论的系统思考。安东尼·奥利弗-史密斯和苏珊娜·m.霍夫曼从人类学对灾难的定义以及相关学术动态开始讨论,涉及了与生态、物质和社会-文化联结的人类学灾难研究的理论与方法,并辅以相关的文章,对人类学灾难研究的贡献和对地方场景中救援与重建的潜在价值进行了描述。

关键词：灾难人类学人类学理论和方法地方场景与知识

EFFECT OF TOPICALLY ADm.NISTERED PROSTAm.DE AND PROSTAGLANDIN ANALOGS ON CENTRAL CORNEAL THICKNESS

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国际眼科杂志 2003年第1期3卷 64-64页

作者： m.Hatanaka I.R.Elias G.A.S.Firm. J.A.Ferreira S.J.Khater A.G.Pinheiro C.m.rita R.susanna-Jr. Hospital Das Clinicas da Faculdade de m.dicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP BrazilHospital Das Clinicas da Faculdade de Medicina da USP Brazil

Purpose: To determ.ne if ocular treatm.nt with topically adm.nistered prostam.de or prostaglandin analogs can reduce central corneal thickness (CCT). m.thods: We retrospectively analyzed the data of glaucom.tous patients who had their CCT m.asured before and during m.notherapy treatm.nt with either latanoprost 0.05%, travoprost 0.004% or bim.toprost 0.03%. 62 patients were qualified for analysis. One eye of each subject was ran-

关键词： PROSTAm.DE 前列腺素类似物前列胺局部用药角膜中央厚度影响

Cell:新分子或可有效清除肝脏和血液中的脂肪

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现代生物医学进展 2017年第4期17卷 I0004-I0004页

作者： Brian Finan Christoffer Clem.ensen Zhim.ng Zhu Kerstin Stem.er Karine Gauthier Luisa m.uum. ller m.ri De Angelis Kristin m.reth Frauke Neff Diego Perez-Tilve Katrin Fischer Dom.nik Lutter m.guel A. S aacute nchez-Garrido Peng Liu Jan Tuckerm.nn m.hsen m.lehm.r m.rc E. Healy Achim.Weber m.thias Heikenwalder m.rtin Jastroch m.xim.lian Kleinert Sigrid Jall Sara Brandt Fr eacute d eacute ric Flam.nt Karl-Werner Schram. Heike Bieberm.nn Yvonne D oum. ring Christian Weber Kirk m. Habegger m.chaela Keuper Vasily Gelfanov Fa Liu Josef K oum. hrle Jan Rozm.n Helm.t Fuchs Valerie Gailus-Durner m.rtin Hrabě de Angelis susanna m. Hofm.nn Bin Yang m.tthias H. Tsch oum. p Richard Dim.rchi Tim. D. m.uum. ller Institute for Diabetes and Obesity Helmholtz Diabetes Center at Helmholtz Zentrum München German Research Center for Environmental Health (GmbH) 85764 Neuherberg Germany Departm.nt of Chem.stry Indiana University Bloomington IN 47405 USA Institut de Génom.que Fonctionnelle de Lyon Université de Lyon Centre National de la Recherche Scientifique (CNRS) Institut National de la Recherche Agronomique (INRA) École Normale Supérieure de Lyon 69364 Lyon France m.lecular EXposom.cs Helmholtz Zentrum München German Research Center for Environmental Health (GmbH) 85764 Neuherberg Germany Germ.n m.use Clinic Institute of Experimental Genetics Helmholtz Zentrum München German Research Center for Environmental Health 85764 Neuherberg Germany Division of Endocrinology Department of Internal Medicine Metabolic Diseases Institute University of Cincinnati College of Medicine Cincinnati OH 45237 USA Institute of Com.arative m.lecular Endocrinology University of Ulm 89081 Ulm Germany Departm.nt of Pathology and m.lecular Pathology University Zurich and University Hospital Zurich 8091 Zurich Switzerland Institute of Virology Technische Universität München 81675 Munich Germany Institute of Experim.ntal Pediatric Endocrinology Charité-Universitätsmedizin Berlin Berlin 13353 Germany Departm.nt of m.dicine Institute for Cardiovascular Prevention Ludwig-Maximilians-Universität München 80336 Munich Germany Com.rehensive Diabetes Center and Departm.nt of m.dicine-Endocrinology Diabetes & Metabolism University of Alabama at Birmingham Birmingham AL 35294 USA Institute for Diabetes and Regeneration Helmholtz Diabetes Center at Helmholtz Zentrum München German Research Center for Environmental Health (GmbH) Neuherberg 85764 Germany Calibrium.LLC Carmel IN 46032 USA Institute for Experim.ntal Endocrinology Charité-Universitätsmedizin Berlin Berlin 13353 Germany Germ.n Center for Diabetes Research (DZD) 85764 Neuherberg Germany

肥胖和糖尿病持续上升代表着我们的社会所面临的一个重大的负担。脂肪肝和动脉粥样硬化是这些代谢疾病常见的后果，但是开发一种高效且又安全的能够逆转肥胖、胰岛素抵抗性、脂肪肝和动脉粥样硬化的药物仍然是全球头等的一项重大的科学... 详细信息

肥胖和糖尿病持续上升代表着我们的社会所面临的一个重大的负担。脂肪肝和动脉粥样硬化是这些代谢疾病常见的后果，但是开发一种高效且又安全的能够逆转肥胖、胰岛素抵抗性、脂肪肝和动脉粥样硬化的药物仍然是全球头等的一项重大的科学挑战。

关键词：脂肪肝 Cell 动脉粥样硬化血液肝脏清除分子代谢疾病