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HVOF-sprayed HAp/S53P4 BG composite coatings on an AZ31 alloy for potential applications in temporary implants

Journal of Magnesium and Alloys 2024年第1期12卷 345-360页

作者： Carlos A.Poblano-Salas John Henao Astrid L.Giraldo-Betancur Paola Forero-Sossa Diego German Espinosa-Arbelaez Jorge A.González-Sánchez Luis R.Dzib-Pérez susana t.estrada-moo Idelfonso E.Pech-Pech CIAtEQ A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYt-CIAtEQ A.C. Av.Manantiales 23-AParque Industrial Bernardo QuintanaEl MarquésQuerétaro 76246Mexico CONAHCYt-Cinvestav Libramiento Norponiente#2000.Fraccionamiento Real de JuriquillaQuerétaro 76230Mexico Universidad tecnológica de Querétaro Av.Pie de la Cuesta N°2501Querétaro 76148Mexico CIDESI Av.Playa Pie de la Cuesta No 702Col.San PabloQuerétaro 76125Mexico Center for Corrosion Research Autonomous University of CampecheAv.Héroe de Nacozari No.480P.C.24070San Francisco de CampecheCam.Mexico

Bioactive thermal spray coatings produced via high-velocity oxygen fuel spray(HVOF)from hydroxyapatite(HAp)and bioactive glasses(BG)have the potential to be employed on temporary implants due to the ability of both HAp and BG to dissolve and promote osseointegration,considering that both phases have different reaction and dissolution rates under in-vitro *** the present work,75%***-25%wt.S53P4 bioactive glass powders were HVOF-sprayed to obtain HAp/S53P4 BG composite coatings on a bioresorbable AZ31 *** study is focused on exploring the effect of the stand-off distance and fuel/oxygen ratio variation as HVOF parameters to obtain stable structural coatings and to establish their effect on the phases and microstructure produced in those *** characterization techniques,such as scanning electron microscopy,X-ray diffraction,and Fourier transform infrared spectroscopy,were employed to characterize relevant structural and microstructural properties of the composite *** results showed that thermal gradients during coating deposition must be managed to avoid delamination due to the high temperature achieved(max 550℃)and the differences in coefficients of thermal *** was also found that both spraying distance and oxygen/fuel ratio allowed to keep the hydroxyapatite as the main phase in the *** addition,in-vitro electrochemical studies were performed on the obtained HAp/S53P4 BG composite coatings and compared against the uncoated AZ31 *** results showed a significant decrease in hydrogen evolution(at least 98%)when the bioactive coating was applied on the Mg alloy during evaluation in simulated body fluid(SBF).

关键词： Coatings Composites thermal spray temporary implants Hydrogen evolution

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Inhibitory activities of microalgal fucoxanthin againstα-amylase,α-glucosidase, and glucose oxidase in 3t3-L1cells linked to type 2 diabetes

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Journal of Oceanology and Limnology 2019年第3期37卷 928-937页

作者： KAWEE-AI Arthitaya KIM Aaron taehwan KIM Sang moo Department of Marine Food Science and technology Gangneung-Wonju National UniversityGangneung 25457Republic of Korea Department of Biotechnology Chiang Mai UniversityChiang Mai 50200Thailand Department of Food Science and Biotechnology Kyung Hee UniversityYongin 17104Republic of Korea

Postprandial hyperglycemia is an early indication of type 2 diabetes and the target of many anti-diabetic and anti-obesity studies.α-Glucosidase and α-amylase are the crucial factors in regulating starch digestion and glucose absorption,making them key targets for many studies to treat postprandial *** studied the inhibitory activities of microalgal fucoxanthin against rat-intestinalα-glucosidase and pancreaticα-amylase along with the antidiabetic eff ect to induce diff erentiation in 3t3-L1 pre-adipocytes using Oil Red-O *** displayed strong hindrance activities towardα-amylase in a concentration-dependent manner,with an IC50 value of 0.68mmol/L,whereas weak inhibitory activity against α-glucosidase,with an IC 50 value of 4.75 mmol/*** also considerably elevated glucose oxidase activity in 3t3-L1 cells by 31.3%at 5μmol/*** adipocyte differentiation,fucoxanthin showed lipid accumulation in 3t3-L1 cells with no cytotoxicity up to 20μmol/***,fucoxanthin had no inhibitory activity on glucose-6-phosphate *** results suggest that fucoxanthin might be useful for the prevention of obesity or diabetes by inhibiting carbohydrate-hydrolyzing enzymes and lipid accumulation and be utilized as an ingredient for a functional food or dietary supplement.

关键词： α-glucosidase amylase diabetes fucoxanthin glucose oxidase microalgae

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Quintuple Band Antenna for Wireless Applications with Small Form Factor

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Computers, Materials & Continua 2021年第3期66卷 2241-2251页

作者： Amir Haider tayyaba Khan MuhibUr Rahman Byung moo Lee Hyung Seok Kim Department of Intelligent Mechatronics Engineering Sejong UniversitySeoul05006Korea Department of telecommunication Engineering University of Engineering and TechnologyTaxila47050Pakistan Department of Electrical Engineering Polytechnique MontrealMontrealQC H3T 1J4Canada

A coplanar waveguide-fed quintuple band antenna with a slotted circular-shaped radiator for wireless applications with a high isolation between adjacent bands is presented in this *** proposed antenna resonates at multiple frequencies with corresponding center frequencies of 2.35,4.92,5.75,6.52,and 8.46 *** intended functionality is achieved by introducing a circular disc radiator with five slots and a U-shaped slot in the *** proposed antenna exhibits coverage of the maximum set of wireless applications,such as satellite communication,worldwide interoperability for microwave access,wireless local area network(WLAN),long-distance radio telecommunications,and X-band/Satcom wireless *** simulation and measurement results of the proposed fabricated antenna demonstrate the high isolation between adjacent bands.A stable realized gain with an advantageous radiation pattern is achieved at the operating frequency *** proposed simple design,compact structure,and simple feeding technique make this antenna suitable for integration in several wireless communication applications,where the portability of devices is a significant *** proposed antenna is anticipated to be an appropriate candidate for WLAN,long-term evolution,and fifth-generation mobile communication because of its multi-operational bands and compact size for handheld devices.

关键词： Coplanar waveguide isolated adjacent bands satellite WiMAX WLAN 5G communication

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Disposition and tissue distribution of imatinib in a liposome formulation after intravenous bolus dose to mice

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药学学报 2010年第7期45卷 901-908页

作者： moo Kai Shing RADHAKRISHNAN Shantini tEOH Magdalene NARAYANAN Prasad BUKHARI Nadeem Irfan SEGARRA Ignacio Department of Pharmaceutical technology School of Pharmacy and Health SciencesInternational Medical University(Malaysia)

Imatinib is an efficacious anticancer drug with a spectrum of potential antitumour applications limited by poor biodistribution at therapeutic concentrations to the tissues of *** assess the pharma-cokinetic and tissue distribution profile of imatinib in a liposome *** single dose(6.25 mg·kg-1) in a liposome formulation was administered iv to male *** concentration was measured in plasma,spleen,liver,kidney and brain using a HPLC ***-compartmental pharmacokinetic approach was used to assess the disposition *** plasma disposition profile was biphasic with a plateau-like second *** AUC0→∞ was 11.24 μg·h·mL-1,the elimination rate constant(kel) was 0.348 h-1 and the elimination half life(t1/2) was 2.0 *** mean residence time(MRt) was 2.59 h,VSS was 1.44 L·kg-1 and clearance was 0.56 L·h·*** achieved the highest tissue exposure:CMAX = 18.72 μg·mL-1;AUC0→∞ = 58.18 μg·h·mL-1 and longest t1/2(4.29 h) and MRt(5.31 h).Kidney and spleen AUC0→∞ were 47.98 μg·h·mL-1 and 23.46 μg·h·mL-1,***-life was 1.83 h for the kidney and 3.37 h for the *** penetrated into the brain reaching ～1 μg·*** correction by organ blood flow the spleen showed the largest uptake *** imatinib presented extensive *** drug uptake kinetics showed mechanism differences amongst the *** findings encourage the development of novel imatinib formulations to treat other cancers.

关键词： imatinib pharmacokinetics liposome tissue distribution

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Absorption characteristics of new solvent based on a blend of AMP and 1,8-diamino-p-menthane for CO_2 absorption

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Journal of Environmental Sciences 2012年第5期24卷 897-902页

作者： Sang-Sup Lee Seong-Man Mun Won-Joon Choi Byoung-moo Min Sang-Won Cho Kwang-Joong Oh Department of Environmental Engineering Chungbuk National University Department of Environmental Engineering Pusan National University Corporate R&D Institute Fuel Cell System Development Team Doosan Heavy Industries & Construction Greenhouse Gas Research Center Korea Institute of Energy Research Department of Energy and Environment Korea Polytechnic VII College

Aqueous 1,8-diamino-p-menthane （KIER-C3） and commercially available amine solutions were tested for CO2 absorption. A 2-amino-2-methyl-1-propanol （AMP） solution with an addition of KIER-C3 showed 9.3% and 31.6% higher absorption rate for CO2 than the AMP solution with an addition of monoethanolamine （MEA） and ammonia （NH3）, respectively. the reaction rate constant for CO2 absorption by the AMP/KIER-C3 solution was determined by the following equation： k2,AMP/C3 = 7.702×106 exp （-2248.03/t）. A CO2 loading ratio of the AMP/KIER-C3 solution was also 2 and 3.4-times higher than that of the AMP/NH3 solution and the AMP/MEA solution, respectively. Based on the experimental results, KIER-C3 may be used as an excellent additive to increase CO2 absorption capability of AMP.

关键词： carbon dioxide absorption rate and capacity 1 8-diamino-p-menthane 2-amino-2-methyl-1-propanol

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t6态A356/SiC与Semi-Metallic Pad的干滑动摩擦磨损特性

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稀有金属材料与工程 2008年第12期37卷 2147-2151页

作者：金云学 Jung-moo Lee Suk-Bong Kang 江苏科技大学先进焊接技术省级重点实验室江苏镇江212003 Korea Institute of Machinery and Materials Changwon 641-010Korea

选用A356/SiC复合材料与Semi-metallic pad材料进行干滑动摩擦磨损试验,并采用SEM、XRD、EDS等手段分析了复合材料的摩擦磨损特点及磨损机制。铝基复合材料与该pad间表现出非常出色的耐摩擦磨损特性,在1m/s的低滑动速度下,即使载荷增加... 详细信息

选用A356/SiC复合材料与Semi-metallic pad材料进行干滑动摩擦磨损试验,并采用SEM、XRD、EDS等手段分析了复合材料的摩擦磨损特点及磨损机制。铝基复合材料与该pad间表现出非常出色的耐摩擦磨损特性,在1m/s的低滑动速度下,即使载荷增加到700N也几乎不发生磨损;载荷不大于500N时,磨损率与滑动速度无关,保持非常小的范围。只有在高载荷、高滑动速度下才会有较为明显的磨损。摩擦系数则随载荷增大产生无规则变化,而随滑动速度的增加而减少,但变化幅度在0.1之内。复合材料耐磨特性好的主要原因是,磨损过程中磨损面上迅速形成以氧化物和石墨为主的润滑膜,减少磨损。高载荷、高滑动速度下磨损的主要特点为,复合材料表层形成塑性流动层,大的塑性流动变形使得较软的铝合金基体沿磨损方向以片状形式挤出,形成特殊的磨屑。而不易变形的SiC颗粒则留在磨损面上形成SiC聚集区,该区域又能在一定程度上减少进一步的磨损。

关键词： SiC 铝合金滑动磨损机制摩擦磨损

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On the Relations of Graph Parameters and Its total Parameters

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Acta Mathematicae Applicatae Sinica 2010年第3期26卷 525-528页

作者： Jing-wen Li Zhi-wen Wang Jaeun Lee moo Young Sohn Zhong-fu Zhang En-qiang Zhu Institute of Applied Mathematics Lanzhou Jiaotong University Lanzhou 730070 China School of Mathematics and Computer Science Ningxia University Yinchuan 750021 China Department of Mathematics Yeungnam University Kyongsan 712-749 Korea Department of Applied Mathematics Changwon University Changwon 641 773 Korea

In this paper we get some relations between α（G）, α＇（G）, β（G）, β＇（G） and αt（G）, βt（G）. And all bounds in these relations are best possible, where α（G）, α＇（G）,/3（G）, β（G）, αt（G） and βt（G） are the covering number, edge-covering number, independent number, edge-independent number （or matching number）, total covering number and total independent number, respectively.

关键词： Graph covering number edge covering number independent number edge independent number,total covering number total independent number

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热处理工艺对A356/SiCp性能及干滑动摩擦磨损特性的影响

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中国有色金属学报 2008年第8期18卷 1458-1465页

作者：金云学 LEE Jung-moo KANG Suk-bong 江苏科技大学先进焊接技术省级重点实验室镇江212003 Advanced Materials Division Korea Institute of Machinery and Materials Changwon 641-010 Korea

研究分析热处理工艺对A356/SiCp复合材料的硬度、导电率及微观组织的影响,在此基础上研究复合材料的干滑动摩擦磨损特性。结果表明:固溶和t6热处理可显著提高复合材料的硬度,但降低导电率,而低温退火却比较显著地提高导电率;导电率高的... 详细信息

研究分析热处理工艺对A356/SiCp复合材料的硬度、导电率及微观组织的影响,在此基础上研究复合材料的干滑动摩擦磨损特性。结果表明:固溶和t6热处理可显著提高复合材料的硬度,但降低导电率,而低温退火却比较显著地提高导电率;导电率高的低温退火态磨损特性基本与铸态一致,固溶处理及时效处理虽可有效提高硬度,但不提高耐磨性能,这表明t6热处理是否作为制动盘材料时的最佳热处理工艺,有待进一步研究;复合材料的磨损率随载荷的增加而增加,但低载荷时增加缓慢,高载荷时增加迅速;摩擦因数随着热处理工艺而变化,但对载荷变化不敏感,都在较小的范围内波动,基本是稳定的。

关键词： Al/SiCp 复合材料干摩擦热处理摩擦磨损特性

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t6态SiCp/A356高温干滑动摩擦磨损特性研究

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稀有金属材料与工程 2014年第10期43卷 2497-2501页

作者：金云学王小丫童强强 Jung-moo Lee 江苏科技大学江苏省先进焊接技术重点实验室江苏镇江212003 Korea Institute of Machinery and Materials Changwon 641-010Korea

采用t6态的SiCp/A356复合材料,以Al2O3陶瓷球作为对磨材料,借助UMt-2摩擦磨损实验机详细研究了复合材料的高温摩擦磨损性能,并采用SEM、OLS4000等手段分析材料的高温摩擦磨损特性。结果表明：t6态的SiCp/A356复合材料的磨损率随着温度... 详细信息

采用t6态的SiCp/A356复合材料,以Al2O3陶瓷球作为对磨材料,借助UMt-2摩擦磨损实验机详细研究了复合材料的高温摩擦磨损性能,并采用SEM、OLS4000等手段分析材料的高温摩擦磨损特性。结果表明：t6态的SiCp/A356复合材料的磨损率随着温度的增加而增加。当温度低于150℃时,磨损率随温度缓慢增加;继续升高温度,磨损率进入稳定阶段,稳定磨损率为3.18×10-5 mg·cm-1;当温度达到250℃时,磨损率呈线性上升。摩擦系数则随温度在0.40~0.45很小范围内波动,表现出优异的高温摩擦性能。同时,磨损机制由氧化磨损、磨粒磨损和疲劳磨损转变为严重的粘着磨损。

关键词： SiCp/A356 t6热处理高温滑动摩擦磨损磨损机制

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tonicity response element binding protein associated with neuronal cell death in the experimental diabetic retinopathy

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International Journal of Ophthalmology(English edition) 2014年第6期7卷 935-940页

作者： Seong-Jae Kim Hwajin Kim Jeongsook Park Inyoung Chung Hyug-moo Kwon Wan-Sung Choi Ji-Myong Yoo Department of Ophthalmology School of MedicineGyeongsang National University Institute of Health Science Gyeongsang National University Department of Anatomy and Neurobiology BK21 Biomedical CenterSchool of MedicineGyeongsang National University School of Nano-Bioscience and Chemical Engineering Ulsan National Institute and Science and Technology

AIM: to study the contribution of tonicity response element binding protein(ton EBP) in retinal ganglion cell(RGC) death of diabetic retinopathy(DR).MEtHODS: Diabetes was induced in C57BL/6 mice by five consecutive intraperitoneal injections of 55 mg/kg streptozotocin(StZ). Control mice received vehicle(phosphate-buffered saline). All mice were killed 2mo after injections, and the extent of cell death and the protein expression levels of ton EBP and aldose reductase(AR) were ***: the ton EBP and AR protein levels and the death of RGC were significantly increased in the retinas of diabetic mice compared with controls 2mo after the induction of diabetes. terminal deoxynucleotidyl transferase(td t)-mediated d UtP nick end labeling(tUNEL)-positive signals co-localized with ton EBP immunoreactive RGC. these changes were increased in the diabetic retinas compared with ***: the present data show that AR and ton EBP are upregulated in the DR and ton EBP may contribute to apoptosis of RGC in the DR.

关键词： aldose reductase diabetes tonicity response element binding protein retinopathy

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