检索结果-南通市图书馆

Adenovirus F40/41 Gastroenteritis-Associated emphysematous Gastritis:A Case Report

在线全文

学校读者我要写书评

暂无评论

Infectious Diseases & Immunity 2024年第2期4卷 93-95页

作者： Maulik K.Lathiya Abigail T.La Nou Maria e.Linnaus susan M.Cullinan emergency Department Mayo Clinic Health SystemEau Claire 54703WIUSA Critical Care Medicine Mayo Clinic Health SystemEau Claire 54703WIUSA General Surgery Department Mayo Clinic Health SystemEau Claire 54703WIUSA

emphysematous gastritis(eG)is a rare form of gastritis characterized by gastric wall *** is associated with a high mortality *** case report describes a patient with a history of atrial fibrillation treated with apixaban,prior stroke,and schizoaffective disorder who showed epigastric tenderness on ***,no peritonitis signs were recorded,and laboratory values revealed high lactate levels and the presence of adenovirus F40/*** computed tomography scan showed extensive portal venous gas in the left hepatic lobe of the liver,as well as pneumatosis involving the entire stomach,indicating *** diagnosis was histologically confirmed and initially managed medically,which proved inefficacious,necessitating surgical intervention in the form of a laparotomy and esophagojejunostomy with Roux-en-Y *** case report suggests a potential association between eG and adenovirus F40/41–induced gastroenteritis,thereby emphasizing the challenging nature of *** underscores the need for comprehensive research to enhance our understanding of its underlying causes and effective treatment strategies.

关键词： emphysema Gastritis Human adenovirus F40/41 Immunocompromised

Association of age at diagnosis of diabetes with subsequent risk of age-related ocular diseases and vision acuity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2024年第4期15卷 697-711页

作者： Si-Ting Ye Xian-Wen Shang Yu Huang susan Zhu Zhuo-Ting Zhu Xue-Li Zhang Wei Wang Shu-Lin Tang Zong-Yuan Ge Xiao-Hong Yang Ming-Guang He The Second Clinical College Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of Ultrasound The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Guangdong eye Institute Department of OphthalmologyGuangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510080Guangdong ProvinceChina Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhou 510080Guangdong ProvinceChina Austin Hospital University of MelbourneMelbourne 3084VictoriaAustralia State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060Guangdong ProvinceChina Monash e-Research Center Faculty of EngineeringAirdoc ResearchNvidia AI Technology Research CenterMonash UniversityMelbourne 3080VictoriaAustralia Department of Ophthalmic epidemiology Centre for Eye Research AustraliaMelbourne 3002VictoriaAustralia

BACKGROUND The importance of age on the development of ocular conditions has been reported by numerous *** may have different associations with different stages of ocular conditions,and the duration of diabetes may affect the development of diabetic eye *** there is a dose-response relationship between the age at diagnosis of diabetes and the risk of cardiovascular disease and mortality,whether the age at diagnosis of diabetes is associated with incident ocular conditions remains to be *** is unclear which types of diabetes are more predictive of ocular *** To examine associations between the age of diabetes diagnosis and the incidence of cataract,glaucoma,age-related macular degeneration(AMD),and vision *** Our analysis was using the UK *** cohort included 8709 diabetic participants and 17418 controls for ocular condition analysis,and 6689 diabetic participants and 13378 controls for vision *** diseases were identified using inpatient records until January *** acuity was assessed using a *** During a median follow-up of 11.0 years,3874,665,and 616 new cases of cataract,glaucoma,and AMD,respectively,were identified.A stronger association between diabetes and incident ocular conditions was observed where diabetes was diagnosed at a younger *** with type 2 diabetes(T2D)diagnosed atears[HR(95%CI):2.71(1.49-4.93)],45-49 years[2.57(1.17-5.65)],50-54 years[1.85(1.13-3.04)],or 50-59 years of age[1.53(1.00-2.34)]had a higher risk of AMD independent of glycated haemoglobin.T2D diagnosedears[HR(95%CI):2.18(1.71-2.79)],45-49 years[1.54(1.19-2.01)],50-54 years[1.60(1.31-1.96)],or 55-59 years of age[1.21(1.02-1.43)]was associated with an increased cataract risk.T2D diagnosedears of age only was associated with an increased risk of glaucoma[HR(95%CI):1.76(1.00-3.12)].HRs(95%CIs)for AMD,cataract,and glaucoma associated with type 1 diabetes(T1D)were 4.12(1.99-8.53),

关键词： Diabetes Age at diagnosis Cataract Glaucoma Age-related macular disease Vision acuity

Breeding better cultivars,faster:applications of new technologies for the rapid deployment of superior horticultural tree crops

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Horticulture Research 2014年第1期1卷 198-205页

作者： Steve van Nocker susan e Gardiner Department of Horticulture Michigan State UniversityEast LansingMI 48824 The New Zealand Institute for Plant&Food Research Limited Plant and Food Research Palmerston North Private Bag 11030 Manawatu Mail Centre Palmerston North4442New Zealand

Woody perennial plants,including trees that produce fruits and nuts of horticultural value,typically have long breeding cycles,and development and introduction of improved cultivars by plant breeders may require many breeding cycles and dozens of ***,recent advances in biotechnologies and genomics have the potential to accelerate cultivar development greatly in all *** mini-review summarizes approaches to reduce the number and the duration of breeding cycles for horticultural tree crops,and outlines the challenges that remain to implement these into efficient breeding pipelines.

关键词： cultivar breeding crops

The Japanese ladybirds, Coccinula crotchi and Coccinula sinensis, are infected with very closely related strains of male-killing Flavobacterium

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2014年第6期21卷 699-706页

作者： Sherif elnagdy susan Messing Michael e. N. Majerus Department of Genetics University of Cambridge Downing Street Cambridge CB2 3EH UK Botany Department Faculty of Science Cairo University Giza Egypt University of Rochester Rochester New York USA Department of Biostatistics and Computational Biology University of Rochester Rochester New York USA

Male-killing is 1 of 4 known strategies that inherited parasitic endosymbionts have evolved to manipulate their host＇s reproduction. In early male-killing, infected male offspring are killed early in embryogenesis. Within the Insecta, male-killing bacteria have been found in a wide range of hosts. The Coccinellidae families of beetles, better known as ladybirds, are particularly prone to male-killer invasion. In samples of the coccinellid, Coc- cinula crotchi, from Japan, a new male-killing bacterium was revealed by phenotypic assay. Molecular genetic analysis revealed the identity to be a tetracycline-sensitive Flavobac- terium that causes female-biased offspring sex ratio. Furthermore, that Flavobacterium strain was found to be closely related to the Flavobacterium causing male-killing in the congeneric Japanese coccinellid, Coccinula sinensis, which was collected from the same region. However, we found slightly different Flavobacterium strains infecting C. sinen- sis from regions with different environmental conditions. This may be an indication of horizontal transmission of male-killing Flavobacterium between these 2 ladybird spices. Finally, environmental conditions may affect the spread of male-killing bacteria among their hosts.

关键词： Coccinula crotchi Coccinula sinensis endosymbionts Flavobacterium inherited bacteria male-killing sex ratio distorter

Ron receptor-dependent gene regulation of Kupffer cells during endotoxemia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2014年第3期13卷 281-292页

作者： Rishikesh M Kulkarni William D Stuart susan e Waltz Department of Cancer Biology University of Cincinnati Department of Research Cincinnati Veterans Affairs Medical Center

BACKGROUND: Ron receptor tyrosine kinase signaling in macrophages, including Kupffer cells and alveolar macrophages,suppresses endotoxin-induced proinflammatory cytokine/chemokine production. Further, we have also identified genes from Ron replete and Ron deplete livers that were differentially expressed during the progression of liver inflammation associated with acute liver failure in mice by microarray *** important genes and signaling pathways have been identified downstream of Ron signaling during progression of inflammation by this approach, the precise role that Ron receptor plays in regulating the transcriptional landscape in macrophages, and particular in isolated Kupffer cells, has still not been ***: Kupffer cells were isolated from wild-type(TK+/+)and Ron tyrosine kinase deficient(TK-/-) mice. ex vivo, the cells were treated with lipopolysaccharide(LPS) in the presence or absence of the Ron ligand, hepatocyte growth factor-like protein(HGFL). Microarray and qRT-PCR analyses were utilized to identify alterations in gene expression between ***: Microarray analyses identified genes expressed differentially in TK+/+ and TK-/- Kupffer cells basally as well as after HGFL and LPS treatment. Interestingly, our studies identified Mefv, a gene that codes for the anti-inflammatory protein pyrin, as an HGFL-stimulated Ron-dependent ***, lipocalin 2, a proinflammatory gene, which is induced by LPS, was significantly suppressed by HGFL *** results were validated by qRT-PCR studies on Kupffer cells treated with LPS and ***: The studies herein suggest a novel mechanism whereby HGFL-induced Ron receptor activation promotes the expression of anti-inflammatory genes while inhibiting genes involved in inflammation with a net effect of diminished inflammation in macrophages.

关键词： Mst1R Mefv Lcn2 Met receptor Kupffer cells macrophages

enhancing the observing capacity for the surface ocean by the use of Volunteer Observing Ship

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2019年第7期38卷 114-120页

作者： Zong-Pei Jiang Jiajun Yuan susan e.Hartman Wei Fan Ocean College Zhejiang UniversityZhoushan 316021China National Oceanography Centre Southampton SO14 3ZHUK

Knowledge of the surface ocean dynamics and the underlying controlling mechanisms is critical to understand the natural variability of the ocean and to predict its future response to climate *** this paper,we highlight the potential use of Volunteer Observing Ship(VOS),as carrier for automatic underway measuring system and as platform for sample collection,to enhance the observing capacity for the surface *** review the concept,history,present status and future development of the VOS-based in situ surface ocean *** successes of various VOS projects demonstrate that,along with the rapid advancing sensor techniques,VOS is able to improve the temporal resolution and spatial coverage of the surface ocean observation in a highly cost-effective manner.A sustained and efficient marine monitoring system in the future should integrate the advantages of various observing platforms including VOS.

关键词： volunteer observing ship ship of opportunity surface ocean in situ observation sensor

Developing Online Learning Communities:Five Factors to Consider in a Journey without Maps

在线全文

学校读者我要写书评

暂无评论

开放教育研究 2005年第1期11卷 55-57页

作者： susan e.Kerstein Human Services/Social Science Departments National-Louis University USA

Through a three year qualitative research study, the researcher examed how faculty in higher education are thinking about, constructing and developing interactive learning enviorments, and identified five fundeamental foutors to consider in developing effective online learning communities, Which may help to negotiate the new enviorment for students and faculty.

关键词：在线教育在线学习团体交互式学习学习方式

epstein-Barr virus-associated post-transplant lymphoproliferative disorders:beyond chemotherapy treatment

在线全文

学校读者我要写书评

暂无评论

Cancer Drug Resistance 2021年第3期4卷 646-664页

作者： Sanam Shahid susan e.Prockop Department of Pediatrics Memorial Sloan Kettering Cancer CenterNew YorkNY 10065USA

Post-transplant lymphoproliferative disorder(PTLD)is a rare but life-threatening complication of both allogeneic solid organ(SOT)and hematopoietic cell transplantation(HCT).The histology of PTLD ranges from benign polyclonal lymphoproliferation to a lesion indistinguishable from classic monoclonal *** commonly,PTLDs are epstein-Barr virus(eBV)positive and result from loss of immune surveillance over *** for PTLD differs from the treatment for typical non-Hodgkin lymphoma because prognostic factors are different,resistance to treatment is unique,and there are specific concerns for organ *** recipients of HCT have a limited time during which they are at risk for this complication,recipients of SOT have a lifelong requirement for immunosuppression,so approaches that limit compromising or help restore immune surveillance are of high ***,while eBV-positive and eBV-negative PTLDs are not intrinsically resistant to chemotherapy,the poor tolerance of chemotherapy in the post-transplant setting makes it essential to minimize potential treatment-related toxicities and explore alternative treatment ***,reduced-toxicity approaches such as single-agent CD20 monoclonal antibodies or bortezomib,reduced dosing of standard chemotherapeutic agents,and non-chemotherapy-based approaches such as cytotoxic T cells have all been ***,we review the chemotherapy and non-chemotherapy treatment landscape for PTLD.

关键词： Post-transplant lymphoproliferative disease PTLD epstein-Barr virus eBV rituximab CD20 monoclonal antibody immunotherapy chemoimmunotherapy eBV-specific cytotoxic T lymphocytes eBV CTLs

Variable retention in Tasmania, Australia: trends over 16 years of monitoring and adaptive management

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

ecological Processes 2019年第1期8卷 305-317页

作者： Robyn e.Scott Mark G.Neyland susan C.Baker Sustainable Timber Tasmania 99 Bathurst StHobartTasmania 7001Australia School of Natural Sciences and ARC Centre for Forest Value University of TasmaniaPrivate Bag 55HobartTasmania 7001Australia

Background:Variable retention harvesting using aggregated retention(ARN)has been applied in some Tasmanian wet eucalypt forests for>15 *** of ARN in Tasmania differs from most other regions,as forest influence(or the proximity of harvested areas to long-term retention)is primarily used to distinguish ARN from clearfelling rather than retention level,and broadcast burning is used as a regeneration treatment,resulting in a preference for edge aggregates instead of isolated retained *** emphasis on site-level retention of biological legacies and forest influence to facilitate re-establishment of mature forest species ensures that ARN coupes achieve the ecological objectives associated with retention ***:Spatial and survey data collected from operational ARN coupes illustrates the development of this silvicultural practice over time and allows comparisons with conventional *** 90%of ARN coupes have met the forest influence target of>50%.The number of ARN coupes harvested per year has varied,but mean retention levels(29%)and the mean area harvested per coupe(24 ha)have remained the *** influence in ARN coupes has decreased over time,as have perimeter-to-area ratios,largely due to a decrease in the number of island *** these measures of complexity have decreased,ARN coupes still have much greater forest influence,retention,and perimeter-to-area ratios when compared to conventional clearfell,burn and sow(CBS)*** observed decrease in boundary complexity should facilitate regeneration burning in ARN coupes,although no increase in the proportion of burnt seedbed was *** proportion of burnt seedbed is strongly correlated with eucalypt seedling stocking and density in ARN coupes,and these attributes were all significantly lower in recent ARN coupes compared to *** differences appear to be due to achieving better burns in recent CBS coupes,rather than poorer ones in ARN cou

关键词： Retention forestry Silviculture systems Aggregated retention Regeneration burning Regeneration success Forest influence eucalyptus