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Internal hernia as a rare cause of small bowel obstruction:An insight from 13 years of experience

World Journal of Clinical Cases 2025年第7期13卷 21-27页

作者： Payal Kaw Anu Behari supriya sharma Ashok Kumar Rajneesh K Singh Department of Surgical Gastroenterology Sanjay Gandhi Post Graduate Institute of Medical SciencesLucknow 226014UPIndia

BACKGROUND Internal hernia(IH)is a rare culprit of small bowel obstruction(SBO)with an incidence of<1%.It poses a considerable diagnostic challenge requiring a high index of suspicion to prevent misdiagnosis,improper treatment,and subsequent morbidity and *** To determine the clinico-demographic profile,radiological and operative findings,and postoperative course of patients with IH and its association with *** Medical records of 586 patients with features of SBO presenting at a tertiary care centre at Lucknow,India between September 2010 and August 2023 were *** Out of 586 patients,7(1.2%)were diagnosed with *** these,4 had congenital IH and 3 had acquired *** male-to-female ratio was 4:*** median age at presentation was 32 ***-enhanced computed tomography(CECT)was the most reliable investigation for preoperative identification,demonstrating mesenteric whirling and clumped-up bowel *** paraduodenal hernia and transmesenteric hernia occurred with an equal frequency(approximately 43%each).Intraoperatively,one patient was found to have bowel ischemia and one had associated malrotation of *** follow-up,no recurrences were *** IH,being a rare cause,must be considered as a differential diagnosis for SBO,especially in young patients in their 30s or with unexplained abdominal pain or discomfort post-surgery.A rapid imaging evaluation,preferably with CECT,is necessary to aid in an early diagnosis and prompt intervention,thereby reducing financial burden related to unnecessary investigations and preventing the morbidity and mortality associated with closed-loop obstruction and strangulation of the bowel.

关键词： Paraduodenal hernia Internal hernia Mesenteric whirling Bowel obstruction Computed tomography

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Online Assessment System with Offline Capabilities

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Computer Technology and Application 2012年第1期3卷 32-37页

作者： supriya Lohgaonkar Sharad sharma Department of Computer Science Bowie State University Bowie MD 20715 USA

There has been increasing research in developing offline web applications. This paper concentrates on developing a new methodology for the online assessment web applications that could be used while offline. It is important to retrieve the critical data collected during an examination without a provision of a backup mechanism. There is a need for an assessment system that can adapt to work uninterruptedly and without loss of critical data while there is intermittent intemet discontinuity. This paper describes architecture and implementation of online assessment system with offline capabilities. Online assessment system with offline capabilities will not interrupt examinee＇s experience while appearing for an assessment test if intemet connection is not available. A development methodology is designed and a compliant framework is implemented to enhance online assessment system with offline capabilities.

关键词： Offline web application assessment system critical data.

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Ebola virus disease: Recent advances in diagnostics and therapeutics

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Asian Pacific Journal of Tropical Medicine 2019年第9期12卷 385-395页

作者： supriya Jagga Ashish Ranjan sharma Chiranjib Chakraborty Sang-Soo Lee Institute for Skeletal Aging&Orthopedic Surgery Chuncheon Sacred Heart HospitalHallym UniversityChuncheon 24252 Republie of Korea Department of Biotechnology School of Life Science and BiotechnologyAdamas UniversityBarasat Barackpore RdKlltaWest Bengal 700126 lndia

Ebola virus disease(EVD)is associated with haemorrhagic fever in humans and nonhuman primates,with a high rate of fatality(up to 90%).Some outbreaks in human history have proven the lethality of *** recent epidemic of 2014 and 2015 in West Africa was the deadliest of all time(11 284 deaths).To understand the transmission dynamics,we have reviewed the epidemiology of EVD to *** absence of any licensed vaccines or approved drugs against Ebola virus(EBOV)further highlights the severity and crisis level of *** organizations(public and private)are making considerable efforts to develop novel therapeutic approaches or vaccines to contain the outbreak of EBOV ***,we summarized the various potential drugs and vaccines(undergoing multiple phases of clinical trials)that have arisen as an alternative against EBOV,and we highlighted the numerous issues and limitations hindering this ***,an increasing focus on strengthening the medical and civic health structure could provide speedy benefits in containing the spread of EVD,as well as offer a resilient foundation for the deployment of novel drugs and vaccines to the affected countries,once such drugs and vaccines become available.

关键词： Ebola virus Vaccines Therapeutics Ebola outbreaks Diagnostics Epidemiology Haemorrhagic fever

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Anti-inflammatory effects of traditional mixed extract of medicinal herbs(MEMH)on monosodium urate crystal-induced gouty arthritis

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Chinese Journal of Natural Medicines 2017年第8期15卷 561-575页

作者： Ju-Suk Nam supriya Jagga Ashish Ranjan sharma Joon-Hee Lee Jong Bong Park Jun-Sub Jung Sang-Soo Lee Institute For Skeletal Aging&Orthopedic Surgery Hallym University-Chuncheon Sacred Heart HospitalChuncheonGangwon-do24252Republic of Korea Institute of Natural Medicine College of MedicineHallym UniversityChucheonGangwon-do 24252Republic of Korea Hana Oriental Clinic ChucnheonGangwon-do 24433Republic of Korea

Korean oriental medicine prescription is widely used for the treatment of gouty diseases. In the present study, we investigated anti-inflammatory effects of modified Korean herbal formulation, mixed extract of medicinal herbs(MEMH), and its modulatory effects on inflammatory mediators associated with gouty arthritis. Both in vitro and in vivo studies were carried out to assess the anti-inflammatory efficacy of MEMH on monosodium urate(MSU) crystals-induced gouty inflammation. MSU crystals stimulated human chondrosarcoma cell line, SW1353, and human primary chondrocytes were treated with MEMH in vitro. The expression levels of pro-inflammatory mediators and metalloproteases were analyzed. The effect of MEMH on NFκB signaling pathway in SW1353 cells was examined. Effect of MEMH on the mR NA expression level of pro-inflammatory mediators and chemotactic factor from human monocytic cell line, THP-1, was also analyzed. The probable role of MEMH in the differentiation process of osteoblast like cells, SaO S-2, after MSU treatment was also observed. To investigate the effects of MEMH in vivo, MSU crystals-induced ankle arthritic model was established. Histopathological changes in affected joints and plasma levels of pro-inflammatory mediators(IL-1β and TNFα) were recorded. MEMH inhibited NFκB signaling pathway and COX-2 protein expression in chondrocytes. MSU-induced mR NA expressions of pro-inflammatory mediators and chemotactic cytokines were suppressed by MEMH. In MSU crystals-induced ankle arthritic mouse model, administration of MEMH relieved inflammatory symptoms and decreased the plasma levels of IL-1β and TNFα. The results indicated that MEMH can effectively inhibit the expression of inflammatory mediators in gouty arthritis, demonstrating its potential for treating gouty arthritis.

关键词： Gout Monosodium urate crystals Inflammation Chondrocyte Oriental medicine

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Primary pediatric mid-brain lymphoma:Report of a rare pediatric tumor in a rare location

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World Journal of Clinical Cases 2016年第12期4卷 419-422页

作者： Rony Benson supriya Mallick Suvendu Purkait Vaishali Suri K P Haresh Subhash Gupta Dayanand sharma Pramod Kumar Julka Goura Kishore Rath Department of Radiotherapy All India Institute of Medical Sciences Department of Radiation Oncology All India Institute of Medical Sciences Department of Pathology All India Institute of Medical Sciences

Primary central nervous system lymphoma(PCNSL) is a rare disease in pediatric age group. A thirteen-yearold male child presented with complaints of headache for six months, vomiting and diplopia for three days. Magnetic resonance imaging of the brain showed a single lesion of 1.7 cm × 1.6 cm × 1.6 cm in the mid brain and tectum. He underwent a gross total resection of the tumor. The histopathological evaluation revealed B cell high grade non Hodgkin lymphoma. The patient was treated with High dose methotrexate and cranio spinal radiation. The patient was alive without disease 12 mo after completion of treatment. This case highlights importance of keeping PCNSL as differential in brain stem lesions of pediatric patients also. Radiation and chemotherapy remains the most important treatment for such patients.

关键词： Primary Midbrain Lymphoma Paediatric

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自由取向炭/炭复合材料的新型制备及工艺优化（英文）

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新型炭材料 2018年第5期33卷 424-433页

作者： Thakur Sudesh Kumar Raunija Rajeev K.Gautam Sharad Chandra sharma Anil Verma Carbon and Ceramics Laboratory Materials and Mechanical EntityVikram Sarabhai Space Centre Indian Space Research OrganisationThiruvananthapuram 695022KeralaIndia Sustainable Environergy Research Lab(SERL) Department of Chemical Engineering Indian Institute of Technology DelhiHauz-KhasNew Delhi 110016India Materials and Metallurgy Group Materials and Mechanical EntityVikram Sarabhai Space Centre Indian Space Research OrganisationThiruvananthapuram 695022KeralaIndia

采用在炭纤维束的内部浸润熔融沥青的传统方法制备得到的炭/炭(C/C)复合材料难以实现细旦化水平,这是因为单束丝中含有数千根丝,经浸渍后沥青附着,从而引起沥青局部渗出,以及因不均匀沥青稳定性而导致微观结构不均匀。本文通过稳定的中... 详细信息

采用在炭纤维束的内部浸润熔融沥青的传统方法制备得到的炭/炭(C/C)复合材料难以实现细旦化水平,这是因为单束丝中含有数千根丝,经浸渍后沥青附着,从而引起沥青局部渗出,以及因不均匀沥青稳定性而导致微观结构不均匀。本文通过稳定的中间相沥青和分散的短切炭纤维混合、热压和炭化过程制备出细旦化水平的C/C复合材料。探讨了工艺参数对中间相沥青残炭率的影响。通过残炭率/工艺时间、残炭率!(表观密度/实密度)来优化工艺参数。结果表明,通过此法得到了细旦化水平的中间相沥青与炭纤维复合材料。中间相沥青的残炭率随加热升温速率、沥青/炭纤维质量比的增加而降低;随热压压力而增加。在高压力和高质量比下,发生沥青局部渗出。通过调控得到最佳的C/C复合材料制备工艺参数为:热压压力15 MPa,升温速率0. 2℃/min及沥青/炭纤维质量比1∶1。

关键词：石油沥青中间相沥青短切炭纤维热压产率

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