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Heating energy savings potential from retrofitting old apartments with an advanced double-skin façade system in cold climate

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Frontiers in Energy 2020年第2期14卷 224-240页

作者： Yeo Beom yoon Byeongmo SEO Brian Baewon KOH Soolyeon CHO College of Design North Carolina State UniversityRaleighNC27695-7701USA sun&Light Corp.Ltd41Seocho-daero 42-gilSeocho-guSeoulRepublic of Korea

Apartments account for over 60%of total residential buildings and consume a significant portion of primary energy in South *** energy efficiency measures have been implemented for both new apartment constructions and existing apartment *** apartment structures have poor thermal performances,resulting in a high energy *** South Korean government initiated retrofitting projects to improve the energy efficiency in old *** owners typically replace old windows with high-performance windows;however,there is still a demand for better and more innovative retrofit methods for a highly improved energy *** paper proposes an advanced double-skin façade(DSF)system to replace existing balcony windows in old *** the cold climate conditions of Seoul,South Korea,it mainly discusses heating energy *** case models were developed:Base-Case with existing apartment,Case-1 with typical retrofitting,and Case-2 with the proposed DSF *** EnergyPlus simulation program was used to develop simulation models for a floor radiant heating system.A typical gas boiler was selected for low-temperature radiant system *** air flow network method was used to model the proposed DSF *** heating months,i.e.,November to March,and one representative day,i.e.,January 24,were selected for detailed *** main heat loss areas consist of windows,walls,and *** results reveal that the apartment with the DSF retrofit saves 38.8%on the annual heating energy compared to the Base-Case and 35.2%compared to Case-1.

关键词： double-skin façade retrofitting high-rise apartment heating energy building simulation

Nobiletin Prevents Body Weight Gain and Bone Loss in Ovariectomized C57BL/6J Mice

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Pharmacology & Pharmacy 2014年第10期5卷 959-965页

作者： Young-Sil Lee Midori Asai sun-Sil Choi Takayuki Yonezawa Toshiaki Teruya Kazuo Nagai Je-Tae Woo Byung-yoon Cha Research Institute for Biological Functions Chubu University Kasugai Japan Faculty of Education University of the Ryukyus Nishihara Japan Department of Biological Chemistry Chubu University Kasugai Japan Department of Research and Development Erina Co. Inc. Tokyo Japan

Obesity and osteoporosis are associated with estrogen deficiency following menopause. Therefore, it is important to prevent and treat both disorders to maintain a healthy life in postmenopausal women. Nobiletin, a polymethoxylated flavone, exhibits various pharmacologic effects, including anti-tumor and anti-inflammatory activities. Therefore, in this study, we examined the effects of nobiletin on obesity, obesity-related metabolic disorders, and bone mass in ovariectomized (OVX) mice. Mice were divided into four groups and underwent sham operation or OVX. OVX mice were treated with 50 or 100 mg/kg nobiletin, or received vehicle alone (0.3% carboxyl methyl cellulose/0.5% dimethyl sulfoxide). Nobiletin decreased body weight gain and white adipose tissue weight in OVX mice. Nobiletin also decreased triglyceride levels, and tended to reduce plasma total cholesterol and glucose levels. Additionally, nobiletin prevented the reduction in bone mineral density of the trabecular region of the femur in OVX mice. Taken together, our results suggest that nobiletin improves adiposity, dyslipidemia, hyperglycemia, and prevents bone loss in OVX mice. Therefore, nobiletin is expected to have beneficial effects for the prevention and improvement of metabolic disorders and osteoporosis in postmenopausal women.

关键词： Nobiletin Ovariectomy Obesity Lipid and Glucose Metabolism Bone Mineral Density

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首尔Sohsul酒店

现代装饰 2015年第5期 50-59页

作者： Geunju yoon Junghwan Hwang sun Namgoong 姜敏华 1990 uao

细节通常发生在设计过程的后期,尤其对建筑设计来说。然而另一方面,设计师认为在开始阶段就考虑细节也是有可能的,室内设计的这个可能性则更大。密斯·凡·德罗曾说过＂上帝存在于细节之中＂,而库哈斯也说＂没有细节,就只剩下了单纯的... 详细信息

细节通常发生在设计过程的后期,尤其对建筑设计来说。然而另一方面,设计师认为在开始阶段就考虑细节也是有可能的,室内设计的这个可能性则更大。密斯·凡·德罗曾说过＂上帝存在于细节之中＂,而库哈斯也说＂没有细节,就只剩下了单纯的概念＂,足以见得,联结项目始末的正是细节。

关键词：酒店设计过程建筑设计室内设计设计师库哈斯密斯

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Saeng-Kankunbi-Tang(生肝健脾汤) Protects Liver against Oxidative Damage through Activation of ERK/Nrf2 Pathway

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Chinese Journal of Integrative Medicine 2016年第8期22卷 619-628页

作者： In Woo Lee Hee yoon Choi Ju-Hee Lee sun-Dong Park Seung Mo Kim Sae Kwang Ku 赵容杰 Sang Chan Kim Young Woo Kim Hong Sik Choi Department of Internal Oriental Medicine of Hepatology College of Oriental Medicine Daegu Haany University Daegu 38610 Korea Medical Research Center for Globalization of Herbal Formulation College of Oriental Medicine Daegu Haany University Daegu 38610 Korea College of Oriental Medicine Dongguk University Gyeongju 38066 Korea School of Mental Health Jining Medical University JiningShandong Province 272067 China

Objective： To investigate the cytoprotective effects of Saeng-kankunbi-tang（生肝健脾汤, SKT）, a herbal prescription consisting of Artemisia capillaris and Alisma canaliculatum, and its underlying mechanism involved. Methods： In mice, blood biochemistry and histopathology were assessed in carbon tetrachloride（CCl4）-induced oxidative hepatic injury in vivo. The animal groups included vehicle-treated control, CCl4, SKT 500 mg/（kg·day） CCl4＋SKT 200 or 500 mg/（kg·day）. In Hep G2 cell, tert-butyl hydroperoxide（t BHP） induced severe oxidative stress and mitochondrial dysfunction in vitro. The cyto-protective effects of SKT were determined by 3-（4,5-dimethylthiazol）-2,5-diphenyltetrazolium bromide（MTT） assay, fluorescence activated cell sorting analysis and western blotting. Results： The administration of SKT prevented liver damage induced by CCl4 in mice, by inhibition of hepatocyte degeneration and inflammatory cell infiltration as well as plasma parameters such as alanine aminotransferase（P〈0.01）. Moreover, treatment with t BHP induced hepatocyte death and cellular reactive oxygen species production in hepatocyte cell line. However, SKT pretreatment（30–300 μg/m L） reduced this cell death and oxidative stress（P〈0.01）. More importantly, SKT inhibited the ability of t BHP to induce changes in mitochondrial membrane transition in cell stained with rhodamine 123（P〈0.01）. Furthermore, treatment with SKT induced extracellular signal-regulated kinases-mediated nuclear factor erythroid-2-related factor 2（Nrf2） activation as well as the expressions of heme oxygenase 1 and glutamate-cystein ligase catalytic, Nrf2 target genes. Conclusion： SKT has the ability to protect hepatocyte against oxidative stress and mitochondrial damage mediated by Nrf2 activation.

关键词： Saeng-kankunbi-tang mitochondria nuclear factor erythroid-2-related factor 2 oxidative stress liver mouse

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DEGREE OF PREFERRED GROWTH ORIENTATION OF SINGLE STAGEHOT DEFORMED NDFEB MAGNETS

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DEGREE OF PREFERRED GROWTH ORIENTATION OF SINGLE STAGEHOT DE...

Evidence for novel age-dependent network structures as a putative primo vascular network in the dura mater of the rat brain

第8届国际材联电子材料国际研讨会

作者： Y. B. Kim T. S. yoon D. S. sun C. O. Kim Korea Research Institute of Standards and Science Chungnam National University South Korea

Permanent magnets have large applications in modern life, such as in home appliances, speakers, office automation equipment, medical laboratory diagnostic test equipment, and more. As a hardest permanent magnet, NdFeB magnet has been of great interest to manufacturers and researchers since its invention in 1983. Fully dense NdFeB magnets can be prepared by both melt-spinning and powder metallurgy *** melt-spun ribbons of NdFeB alloys have equiaxed and randomly oriented NdFeB grains. In order to get

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Neural Regeneration Research 2015年第7期10卷 1101-1106页

作者： Ho-sung Lee Dai-In Kang Seung Zhoo yoon Yeon Hee Ryu Inhyung Lee Hoon-Gi Kim Byung-Cheon Lee Ki Bog Lee Ki Primo Research Laboratory Division of Electrical Engineering KAIST Institute for Information Technology Convergence Korea Advanced Institute of Science and Technology (KAIST) Nadi Primo Research Institute Graduate School of Integrative Medicine Sun Moon University Pharmacopuncture Medical Research Center Korean Pharmacopuncture Institute Department of Anesthesiology and Pain Medicine College of Medicine Korea University Acupuncture Moxibustion & Meridian Research Group Medical Research Division Korea Institute of Oriental Medicine Department of Veterinary Surgery College of Veterinary Medicine Seoul National University Faculty of Liberal Education Seoul National University Korea Atomic Energy Research Institute

With chromium-hematoxylin staining, we found evidence for the existence of novel age-dependent network structures in the dura mater of rat brains. Under stereomicroscopy, we noticed that chromium-hematoxylin-stained threadlike structures, which were barely observable in 1-weekold rats, were networked in specific areas of the brain, for example, the lateral lobes and the cerebella, in 4-week-old rats. In 7-week-old rats, those structures were found to have become larger and better networked. With phase contrast microscopy, we found that in 1-week-old rats, chromium-hematoxylin-stained granules were scattered in the same areas of the brain in which the network structures would later be observed in the 4- and 7-week-old rats. Such age-dependent network structures were examined by using optical and transmission electron microscopy, and the following results were obtained. The scattered granules fused into networks with increasing age. Cross-sections of the age-dependent network structures demonstrated heavily-stained basophilic substructures. Transmission electron microscopy revealed the basophilic substructures to be clusters with high electron densities consisting of nanosized particles. We report these data as evidence for the existence of age-dependent network structures in the dura mater, we discuss their putative functions of age-dependent network structures beyond the general concept of the dura mater as a supporting matrix.

关键词： nerve regeneration dura mater chromium-hematoxylin staining fascia primo vascular system brain hormone neural regeneration

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Improvement of diabetes and hypertension after gastrectomy: A nationwide cohort study

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World Journal of Gastroenterology 2015年第4期21卷 1173-1181页

作者： Eun Kyung Lee So Young Kim You Jin Lee Mi Hyang Kwak Hak Jin Kim Il Ju Choi Soo-Jeong Cho Young Woo Kim Jong Yeul Lee Chan Gyoo Kim Hong Man yoon Bang Wool Eom sun-Young Kong Min Kyong Yoo Jong Hyock Park Keun Won Ryu Department of Internal Medicine National Cancer CenterGoyang 410-769South Korea College of Medicine/Graduate School of Health Science Business ConvergenceChungbuk National UniversityCheongju 361-763South Korea Department of Surgery National Cancer CenterGoyang 410-769South Korea Department of Laboratory Medicine National Cancer CenterGoyang 410-769South Korea Department of Clinical Nutrition National Cancer CenterGoyang 410-769South Korea

AIM: To evaluate the effect of gastrectomy on diabetes mellitus(DM) and hypertension(HTN) in non-obese gastric cancer patients. METHODS: A total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and 351 hypertensive patients with gastric cancer who had been regularly treated without chemotherapy from January 2005 to December 2010 were selected. They were divided into three groups according to their treatment methods: total gastrectomy(TG), subtotal gastrectomy(STG) and endoscopic resection(ER). RESULTS: The drug discontinuation rate of antidiabetic and anti-hypertensive agents after gastric cancer treatment was 9.7% and 11.1% respectively. DM appeared to be improved more frequently(22.8%) and earlier(mean ± SE 28.6 ± 1.8 mo) in TG group than in the two other groups [improved in 9.5% of ER group(37.4 ± 1.1 mo) and 6.4% of STG group(47.0 ± 0.8 mo)]. The proportion of patients treated with multiple drugs decreased more notably in TG group compared to others(P = 0.001 in DM, and P = 0.035 in HTN). In TG group, adjusted hazard ratio for theimprovement of DM was 2.87(95%CI: 1.15-7.17) in a multi-variate analysis and better control of DM was observed with survival analysis(P < 0.001).CONCLUSION: TG was found to decrease the need for anti-diabetic medications which can be reflective of improved glycemic control, to a greater extent than either ER or STG in non-obese diabetic patients.

关键词： Diabetes Hypertension Gastrectomy Gastric cancer N

Comparison of postpolypectomy bleeding between epinephrine and saline submucosal injection for large colon polyps by conventional polypectomy:A prospective randomized,multicenter study

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World Journal of Gastroenterology 2007年第21期13卷 2973-2977页

作者： Suck-Ho Lee Il-Kwun Chung sun-Joo Kim Jin-Oh Kim Bong-Min Ko Won-Ho Kim Hyun-Soo Kim Dong-IL Park Hyo-Jong Kim Jeong-Sik Byeon Suk-Kyun Yang Byeong Ik Jang sung-Ae Jung yoon-Tae Jeen Jai-Hyun Choi Hwang Choi Dong-Soo Han Jae Suk Song Department of Internal Medicine University of Soonchunhyang at CheonanCheonan & Seoul & BucheonRepublic of Korea Department of Internal Medicine University of Yonsei at SeoulSeoul & WonjuRepublic of Korea Department of Internal Medicine University of Sungkyunkwan at SeoulSeoulRepublic of Korea Department of Internal Medicine University of Kyunghee at SeoulSeoulRepublic of Korea Department of Internal Medicine University of Ulsan at SeoulSeoulRepublic of Korea Department of Internal Medicine University of Youngnam at TaeguTaeguRepublic of Korea Department of Internal Medicine University of Ewha at SeoulSeoulRepublic of Korea Department of Internal Medicine University of Korea at SeoulSeoul & AnsanRepublic of Korea Department of Internal Medicine University of Catholic at BucheonBucheonRepublic of Korea Department of Internal Medicine University of Hanyang at KuriKuriRepublic of Korea Department of Preventive Medicine University of KwandongKangneungRepublic of Korea

AIM:To evaluate and compare the clinical outcomes of prophylactic submucosal saline-epinephrine injection and saline injection alone for large colon polyps by conventional polypectomy. METHODS:A prospective study was conducted from July 2003 to July 2004 at 11 tertiary endoscopic centers. Large colon polyps (> 10 mm in diameter) wererandomized to undergo endoscopic polypectomy with submucosal saline-epinephrine injection (epinephrine group) or normal saline injection (saline group). Endoscopic polypectomy was performed by the conventional snare method,and early ( 2 cm) and neoplastic polyps were independently and significantly associated with the presence of PPB. CONCLUSION:The prophylactic submucosal injection of diluted epinephrine does not appear to provide an additional advantage over the saline injection alone for the prevention of PPB.

关键词： Colonoscopic polypectomy Bleeding submucosal injection Saline Epinephrine

Quantitative differentiation of phenolic compounds in different varieties of buckwheat cultivars from China, Japan and Korea

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Journal of Agricultural Chemistry and Environment 2013年第4期2卷 109-116页

作者： Jeong Min Seo Da Bin Lee Mariadhas Valan Arasu Qi Wu Tatsuro Suzuki Young-Ho yoon Sang-Won Lee Sang Un Park sun-Ju Kim Department of Bio-Environmental Chemistry Chungnam National University Daejeon South Korea

The aim of this study was to determine the variation of phenolic compounds in common and tartary buckwheats collected from China, Japan and Korea. Two buckwheat varieties of each country were cultivated using nutrient solution and vermiculite in the greenhouse from February to May, 2012 and harvested at two-week intervals. Phenolics such as chlorogenic acid, C-glycosylflavones (orientin, isoorientin, vitexin, and isovitexin), rutin, and quercetin were quantified using high performance liquid chroma-tography (HPLC). At 17, 29, 44, 58, and 72 days after sowing (DAS), before harvesting each organs, rutin content of cultivars from China and Korea at 17 DAS was the highest (mean 43.63 and 39.95 mg?g–1 DW, respectively) than that of 29 and 44 DAS. However, two varieties from Japan at 44 DAS were documented maximum;whereas, the amount of rutin in “Hokkai T10” harvested at 44 DAS (58.36 mg?g–1 DW) was the highest of all cultivars. Rutin level in the leaves and stems at 72 DAS were comparatively higher than at 58 DAS. The highest of rutin content was found at 72 DAS (73.33 mg?g–1 DW) in “Hokkai T10” leaves followed by “Daegwan No.3-3” (61.13 mg?g–1 DW), “rice tartary” (53.89 mg?g–1 DW). Rutin content of flowers was presented as the highest amount in “Hokkai T10” at 72 DAS (88.3 mg?g–1 DW) was approximately 14-fold higher than that of 58 DAS (6.44 mg?g–1 DW). However, rutin content of flower in “Xiqiao No.2” was 3-fold higher at 72 DAS than at 58 DAS. Rutin and total phenolic compounds content in flowers, leaves, and stems were higher in the order. The content of four C-glycosylflavones in common buckwheat was higher than those in tartary buckwheat, but rutin content which accounted >90% of the total phenolic compounds was higher in tartary buckwheat. The highest amounts of chlorogenic acid and quercetin were measured in the flower of “Xiqiao No.2” (6.85 and 11.69 mg?g–1 DW, respectively). Based on these results, the presence of different phenolic compounds in all the varieti

关键词： Buckwheat Phenolic Compounds Rutin Functional Food