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Space advanced technology demonstration satellite

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Science China(Technological Sciences) 2024年第1期67卷 240-258页

作者： ZHANG XiaoFeng CHEN Wen ZHU XiaoCheng MENG Na HE JunWang BI XingZi ZHANG YongHe SHI Qi LI Fei LIU Rui FENG ZhengGong LIU Liu LI JinSong WU HaiChen XU DongXiao LI TaiJie HUANG JiangJiang LIU Shuo LI TianTong YU XianSheng GAO Yang ZHOU Heng BAN HanYu ZHANG YanLi ZHANG YueTing YANG YingQuan HE Tao DUAN XuLiang CHEN Xin WANG YaMin sun AnTai ZHANG KuoXiang sun Ying WANG YaoBin FAN ChengCheng XIONG ShaoLin LI XinQiao WEN XiangYang LING ZhiXing sun xiaojin ZHANG Chen BAI XianYong WANG ZhanShan DENG YuanYong TIAN Hui YANG JianFeng XUE HongBo SANG Peng LIU JinGuo ZHENG HuiLong ZHU Xiang HE JianWu LI Hui XU LuXiang XU ShuYan CHEN WenWu LIU ZhenDong WANG ZhaoLi MAO XiangLong GAO Rong LI ZongXuan DING GuoPeng WANG XinYu DOU RunJiang WENG LuBin LUO Hao WANG YaPing LIANG XianFeng FANG ZiRuo Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 201203China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China National Astronomical Observatory of China Beijing 100101China Shanghai Institute of Technical Physics Chinese Academy of SciencesShanghai 200083China Institute of Precision Optical Engineering School of Physics Science and EngineeringTongji UniversityShanghai 200092China School of Earth and Space Sciences Peking UniversityBeijing 100871China Xi’an Institute of Optics and Precision Mechanics Chinese Academy of SciencesXi’an 710119China National Space Science Center Chinese Academy of SciencesBeijing 100190China Shenyang Institute of Automation Chinese Academy of SciencesShenyang 110016China Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China Shanghai Institute of Organic Chemistry Chinese Academy of SciencesShanghai 200032China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 310024China Nanyang Technological University Singapore 569830Singapore Dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023China Technical Institute of Physics and Chemistry Chinese Academy of SciencesBeijing 100049China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Institute of Semiconductors Chinese Academy of SciencesBeijing 100083China Institute of Automation Chinese Academy of SciencesBeijing 100190China School of Aeronautics and Astronautics Zhejiang UniversityHangzhou 310058China

The Space Advanced Technology demonstration satellite(SATech-01),a mission for low-cost space science and new technology experiments,organized by Chinese Academy of Sciences(CAS),was successfully launched into a sun-synchronous orbit at an altitude of~500 km on July 27,2022,from the Jiuquan Satellite Launch *** as an experimental platform for space science exploration and the demonstration of advanced common technologies in orbit,SATech-01 is equipped with 16 experimental payloads,including the solar upper transition region imager(SUTRI),the lobster eye imager for astronomy(LEIA),the high energy burst searcher(HEBS),and a High Precision Magnetic Field Measurement System based on a CPT Magnetometer(CPT).It also incorporates an imager with freeform optics,an integrated thermal imaging sensor,and a multi-functional integrated imager,*** paper provides an overview of SATech-01,including a technical description of the satellite and its scientific payloads,along with their on-orbit performance.

关键词： SATech-01 spacecraft design scientific instruments on-orbit performance

中国式职业教育现代化进程中高职院校形象传播的价值意蕴、逻辑理路与优化路径

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宁波职业技术学院学报 2024年第2期28卷 10-14,20页

作者：吴昊吴云飞孙晓瑨常州信息职业技术学院江苏常州213164 常州机电职业技术学院江苏常州213164

优化高职院校形象传播,是当前我国推动现代职业教育高质量发展的重要任务,有利于改变社会对职业教育的刻板印象,推动职业教育打造特色品牌、畅通职教体系和形成中国标准。在中国式职业教育现代化进程中,高职院校开展形象传播应以存在的... 详细信息

优化高职院校形象传播,是当前我国推动现代职业教育高质量发展的重要任务,有利于改变社会对职业教育的刻板印象,推动职业教育打造特色品牌、畅通职教体系和形成中国标准。在中国式职业教育现代化进程中,高职院校开展形象传播应以存在的现实挑战为导向,基于理念、行为、视觉三层次的形象传播基本逻辑,在认知层面形成“意义体系”传播理念,在机制层面建立整合协同全员传播机制,在举措层面系统化、多维度凝聚办学理念价值、注重行为互动展示、构建视觉传播矩阵,并在反馈控制层面,完善形象传播螺旋管理闭环,为提升高职院校的知晓度、关注度、满意度发挥积极作用。

关键词：中国式职业教育现代化高职院校形象传播

扁蒴藤素通过活性氧调控PI3K/AKT通路增强顺铂诱导鼻咽癌细胞凋亡

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南方医科大学学报 2024年第5期44卷 904-912页

作者：王媛媛陈腾从小凡李依然陈蕊张配孙小锦赵素容蚌埠医科大学药学院//安徽省生化药物工程技术研究中心安徽蚌埠233030

目的观察扁蒴藤素和顺铂对鼻咽癌细胞增殖和凋亡的影响,并探讨其作用机制。方法CCK-8法检测不同浓度扁蒴藤素、顺铂处理24 h后HNE-1和CNE-2Z细胞的存活率,集落形成实验观察细胞集落形成能力,流式细胞术检测细胞凋亡和活性氧(ROS)水平,We... 详细信息

目的观察扁蒴藤素和顺铂对鼻咽癌细胞增殖和凋亡的影响,并探讨其作用机制。方法CCK-8法检测不同浓度扁蒴藤素、顺铂处理24 h后HNE-1和CNE-2Z细胞的存活率,集落形成实验观察细胞集落形成能力,流式细胞术检测细胞凋亡和活性氧(ROS)水平,Western blotting检测蛋白表达。N-乙酰半胱氨酸(NAC)预处理后,检测细胞增殖、凋亡及通路的影响。结果CCK-8结果显示,扁蒴藤素和顺铂均可抑制HNE-1和CNE-2Z细胞的存活率(P<0.05)。与单用扁蒴藤素或顺铂相比,联合使用明显抑制细胞存活率和细胞集落形成能力(P<0.05),升高细胞凋亡率(P<0.01)和细胞内ROS水平(P<0.01),上调Bax、Cleaved caspase-3和Cleaved PARP的表达(P<0.05),下调Bcl-2、Mcl-1和PARP的表达(P<0.05),同时,下调细胞中p-PI3K和p-AKT的表达(P<0.05)。而NAC可部分逆转扁蒴藤素联合顺铂对HNE-1和CNE-2Z细胞的增殖抑制(P<0.01)和凋亡诱导作用(P<0.05),部分恢复p-PI3K和p-AKT的下调作用(P<0.05)。结论扁蒴藤素能增强鼻咽癌细胞对顺铂的增殖抑制和凋亡诱导作用,其机制可能与ROS介导的PI3K/AKT信号通路失活有关。

关键词：鼻咽癌扁朔藤素顺铂活性氧 PI3K/AKT信号通路

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Outer-surface Covering of Nanochannels with Hydrogel for Highly Sensitive and Specific Cr(VI)Detection Through Analyte-caused Charge Change in Hydrogel

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Chemical Research in Chinese Universities 2024年第2期40卷 326-332页

作者： LIU Huan sun Xueting DAI Yu ZHANG xiaojin XIA Fan Faculty of Materials Science and Chemistry China University of GeosciencesWuhan430074P.R.China

Nanochannels have made great progress and are a promising platform for detecting a series of ***,most nanochannels are modified on the inner wall,while ignoring the outer ***,we modified the outer surface of nanochannels with *** from other reported outer-surface modification methods,we directly cover nanochannels with hydrogel to form heterogeneous *** selected hydrogel hardly adsorbs other ions and shows specific adsorption for Cr(VI).The adsorption sites in hydrogel are homogeneous,and Cr(VI)adsorption onto hydrogel is endothermic and *** charge in hydrogel changes after Cr(VI)adsorption,and the resulting current changes can be used for the detection of Cr(VI)with the detection limit of 10−11 mol/*** platform is expected to be used for Cr(VI)detection in living organisms,especially within *** work provides a new approach for outer-surface modification of nanochannels and offers a new choice for nanochannel detection platforms.

关键词： Nanochannel Hydrogel Heterogeneous membrane Cr(VI)detection

Design and Analysis of a Single-Stage Transonic Centrifugal Turbine for organic Rankine cycle(ORC)

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Journal of Thermal Science 2020年第1期29卷 32-42页

作者： WANG Naian sun xiaojin HUANG Diangui School of Energy and Power Engineering University of Shanghai for Science and technology

The recovery of low temperature heat sources is a hot topic in the *** ORC system can effectively use the low temperature heat *** its main output device,the performance of the turbine is very *** single stage transonic turbine has the characteristics of small size and large output *** this paper,the complete design process of a transonic centrifugal turbine with R245fa in low working temperature condition is *** the design conditions,the shaft power and the wheel efficiency of the centrifugal turbine can reach 1.12 MW and 83.61%,*** addition,a thermodynamic ORC cycle is presented and the off-design conditions of the turbine and its influence on the system are studied in *** results obtained in the present work show that the single-stage transonic centrifugal turbine can be regarded as a potential choice to be applied in small scale ORC systems.

关键词： ORC transonic centrifugal turbine design and off-design operating conditions performance analysis computational fluid dynamics

Post-transcriptional regulation of grain weight and shape by the RBP-A-J-K complex in rice

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Journal of Integrative Plant Biology 2024年第1期66卷 66-85页

作者： Ding Ren Hui Liu Xuejun sun Fan Zhang Ling Jiang Ying Wang Ning Jiang Peiwen Yan Jinhao Cui Jinshui Yang Zhikang Li Pingli Lu xiaojin Luo State Key Laboratory of Genetic Engineering and MOE Engineering Research Center of Gene Technology School of Life SciencesFudan UniversityShanghai 200438China State Key Laboratory of Crop Stress Adaptation and Improvement School of Life SciencesHenan UniversityKaifeng 475004China MOE Key Laboratory of Crop Physiology Ecology and Genetic Breeding College of AgronomyJiangxi Agricultural UniversityNanchang 330045China State Key Laboratory of Crop Gene Resources and Breeding Institute of Crop SciencesChinese Academy of Agricultural Sciences(CAAS)Beijing 100081China College of Agronomy Anhui Agricultural UniversityHefei 230036China

RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain *** an integrated strategy involving map-based cloning,functional characterizations,and transcriptomic and population genomic analyses,we revealed that RBP-K(LOC_Os08g23120),RBP-A(LOC_Os11g41890),and RBP-J(LOC_Os10g33230)encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related *** of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function ***,RBP-J most likely affects GA pathways,resulting in considerable increases in grain and panicle lengths,but decreases in grain width and *** contrast,RBP-A negatively regulates the expression of genes most likely involved in auxin-regulated pathways controlling cell wall elongation and carbohydrate transport,with substantial effects on the rice grain filling process as well as grain length and ***,RBP-K is relatively ancient and highly conserved,whereas RBP-J and RBP-A are more ***,the RBP-A-J-K complex may represent a typical functional model for many RBPs and protein complexes that function at transcriptional and post-transcriptional levels in plants and animals for increased functional consistency,efficiency,and versatility,as well as increased evolutionary *** results clearly demonstrate the importance of RBP-mediated post-transcriptional regulation for the diversity of complex ***,rice grain yield and quality may be enhanced by introducing various complete or partial loss-of-function mutations to specific RBP genes using clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 technology and by exploiting desirable natural tri-genic allelic combinations at the loci encoding the components of the RBP-A-J-K complex through marker-assisted select

关键词： GL11 grain weight and shape post-transcriptional regulation RNA-binding proteins

Acute Hepatitis B--China,2005−2019

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China CDC weekly 2020年第30期2卷 559-563页

作者： Ning Miao Hui Zheng xiaojin sun Fuzhen Wang Guomin Zhang Zundong Yin National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina

Introduction:Hepatitis B is a major public health threat in *** subtyping of acute hepatitis B(AHB)has been reported to China’s National Notifiable Disease Reporting System(NNDRS)since *** divided the years since NNDRS reporting started into three stages:a“primary stage”(2005−2008),a“catch-up stage”(2009−2012),and an“AHB surveillance pilot stage”(2013−2019).We evaluated characteristics of AHB and progress towards AHB control in these three ***:We obtained data on cases reported to NNDRS between January 1,2005 and December 31,2019 and compared the annual incidence of reported AHB in each of the three stages by region,age,and ***:The incidence of reported AHB declined from 7.52 per 100,000 in 2005 to 3.21 per 100,000 in 2019—a decrease of 57.31%.The annual incidences of AHB in the primary stage,the catch-up stage,and the AHB surveillance pilot stage were 7.45 per 100,000,5.78 per 100,000,and 4.26 per 100,000,respectively;7 provincial-level administrative divisions(PLADs)had an annual incidence of more than 10 per 100,000 in the primary stage,5 PLADs in the catch-up stage,and 1 in the AHB surveillance pilot *** group aged 20−29 years old had the highest annual rate of reported AHB in the primary stage(14.35 per 100,000)and in the catch-up stage(10.42 per 100,000),and the group aged 30−39 years old had the highest annual rate in the surveillance pilot stage(5.89 per 100,000).AHB affected males and females in all age *** and Implications for Public Health Practice:The incidence of AHB had decreased significantly since the start of the NNDRS reporting in 2005,but additional action is needed to eliminate AHB in *** B vaccine(HepB)coverage in adults should be increased to reduce new AHB cases among people over 20 years old,epidemiological investigations of AHB cases should be conducted to identify risk factors for infection,and prevention of mother-to-child transmission needs to be strengthened.

关键词： prevention mother eliminate

Progress Towards Hepatitis A Control and Prevention Through 2019:the National Immunization Program of China

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China CDC weekly 2020年第31期2卷 591-595页

作者： xiaojin sun Fuzhen Wang Guomin Zhang Hui Zheng Ning Miao Zundong Yin Zhijie An National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina

Hepatitis A is an infectious liver disease caused by hepatitis A virus(HAV)that results in mild to severe *** is spread to immunologically naïve persons who ingest food or water contaminated with feces from HAV-infected individuals(1).Hepatitis A is often seen in sporadic cases,but is also seen in large outbreaks,such as the 1988 outbreak in Shanghai that caused over 300,000 cases and huge economic losses(2).

关键词： cases infected illness

耦合绿电煤气化生产化学品过程CO_(2)减排潜力

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洁净煤技术 2024年第4期30卷 111-119页

作者：孙益郭啸晋徐祥中国科学院工程热物理研究所能源动力研究中心北京100190 中国科学院大学北京100049 江苏中科能源动力研究中心江苏连云港222069

耦合可再生能源生产的绿电为煤气化反应供热以消除燃烧供热实现自热平衡的影响,不仅可有效降低气化过程CO_(2)排放量,还能提高合成气氢碳比(H/C),从而降低以煤气化为源头生产化学品的水煤气变换工段中CO_(2)排放。对不同类型的常规气化... 详细信息

耦合可再生能源生产的绿电为煤气化反应供热以消除燃烧供热实现自热平衡的影响,不仅可有效降低气化过程CO_(2)排放量,还能提高合成气氢碳比(H/C),从而降低以煤气化为源头生产化学品的水煤气变换工段中CO_(2)排放。对不同类型的常规气化反应器和相应的耦合绿电反应器进行建模与模拟,判明合成气组分的主要影响因素,分析了温度对合成气组分的影响,探讨合成气H/C随温度变化规律,并计算不同化学品生产过程的CO_(2)减排潜力。结果表明,耦合绿电的气化反应器合成气中CO_(2)排放较常规气化反应器分别减少了12.63%(固定床)、11.01%(气流床)、9.23%(输运床)和5.12%(流化床),且H/C呈上升趋势;温度对合成气组分影响较大,热解解耦和气化反应的反应器一定程度上影响合成气组分;温度低于1500 K时,H/C随温度升高而降低;温度高于1500 K时,H/C随温度升高而缓慢升高;耦合绿电煤基化学品生产过程CO_(2)排放大幅减少,操作在更低温度和压力的气化反应器具有更高的合成气H/C和CO_(2)减排潜力;耦合绿电的固定床系统效率优势明显;考虑到耦合绿电的高温反应器存在的技术困难,耦合绿电的固定床、流化床和输运床反应器更具可行性。

关键词：煤气化流程模拟 CO_(2)减排氢碳比绿电