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联合时空注意力的视频显著性预测

吉林大学学报（工学版） 2024年第6期54卷 1767-1776页

作者：孙铭会薛浩金玉波曲卫东秦贵和吉林大学计算机科学与技术学院长春130012 吉林大学符号计算与知识工程教育部重点实验室长春130012 上海爱思博特管理咨询有限公司上海200050 光电对抗测试评估技术重点实验室河南洛阳471000

为了解决视频显著性预测任务中时间与空间特征联合建模的问题,提出联合时空注意力机制(COStA),共同提取时间和空间维度的注意信息,突出特定时间和区域的特征供模型来感知。基于该机制,进一步提出视频显著性预测模型TASED-COStA,对比实... 详细信息

为了解决视频显著性预测任务中时间与空间特征联合建模的问题,提出联合时空注意力机制(COStA),共同提取时间和空间维度的注意信息,突出特定时间和区域的特征供模型来感知。基于该机制,进一步提出视频显著性预测模型TASED-COStA,对比实验表明:COStA机制能为神经网络模型在CC、NSS与SIM三个评价指标上获得大于8%的性能提升,TASED-COStA模型能有效地建模视频信息中的时间与空间关系,并给出准确的预测结果。

关键词：计算机应用深度学习计算机视觉卷积神经网络视频显著性预测联合时空注意力机制

基于跨理论模型的吞咽-饮食管理在脑卒中吞咽障碍患者中的应用

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安徽医专学报 2024年第1期23卷 139-141,144页

作者：贾良萍马景孙慧明合肥市第二人民医院安徽合肥230011

目的:探究跨理论模型为指导的吞咽一饮食管理对脑卒中吞咽障碍患者的护理效果。方法:选取医院接受治疗的120例脑卒中吞咽障碍患者,采用随机数表法分为观察组(62例)和对照组(58例)。其中观察组患者采用跨理论模型为指导的吞咽一饮食管理... 详细信息

目的:探究跨理论模型为指导的吞咽一饮食管理对脑卒中吞咽障碍患者的护理效果。方法:选取医院接受治疗的120例脑卒中吞咽障碍患者,采用随机数表法分为观察组(62例)和对照组(58例)。其中观察组患者采用跨理论模型为指导的吞咽一饮食管理护理,对照组患者采用常规护理,对比两组患者的相关参数。结果:护理后,观察组患者的才滕氏吞咽障碍评分、一般自我效能感量表(GSES)子量表评分均高于对照组(P0.05)。护理后第2、4周,观察组患者的卒中专门生存质量量表(SS-QOL)评分高于对照组(P<0.001)。结论:跨理论模型为指导的吞咽-饮食管理可显著改善患者的吞咽功能、营养状态,降低其不良事件发生率,提高患者的自我效能以及生活质量,值得在临床护理中推广。

关键词：脑卒中吞咽障碍跨理论模型吞咽功能生活质量自我效能

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3D打印水凝胶支架在宫腔粘连防治中的应用

国际妇产科学杂志 2024年第3期51卷 290-297页

作者：史明孙铭辉杨微微黄慧华张昌林邓宇斌中山大学附属第七医院科研中心广东省深圳市518107 中山大学医学院中山大学附属第七医院妇产科深圳市中药活性物质筛选与转化研究重点实验室

宫腔粘连(intrauterine adhesion,IUA)常易引发停经、不孕和复发性流产等问题,严重影响女性身心健康。临床上,对IUA的治疗主要采用手术分离方式,术后易复发,治疗效果欠佳。3D生物打印支架成为治疗IUA的前沿领域,可分隔受损区域防止粘连... 详细信息

宫腔粘连(intrauterine adhesion,IUA)常易引发停经、不孕和复发性流产等问题,严重影响女性身心健康。临床上,对IUA的治疗主要采用手术分离方式,术后易复发,治疗效果欠佳。3D生物打印支架成为治疗IUA的前沿领域,可分隔受损区域防止粘连形成,体内可控降解无需手术取出。该支架可用于药物负载、干细胞移植及外泌体的递送,可将药物或生长因子释放到损伤区域,促进组织修复与再生。将负载干细胞或干细胞外泌体的3D打印水凝胶移植到损伤区域,可有效促进IUA的修复并改善妊娠率。3D生物打印可为患者提供个体化治疗方案,联合干细胞或干细胞外泌体的治疗策略有望成为治疗IUA的有力工具。

关键词：宫腔粘连打印,三维干细胞治疗子宫内膜修复

薰衣草醇酰基转移酶基因(AAT)的克隆和表达分析

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江苏农业学报 2024年第4期40卷 599-606页

作者：廖燕尹松松龚林涛闫博文孙明辉苏秀娟王爱凡新疆农业大学农学院新疆乌鲁木齐830052 新疆农业大学薰衣草研究所/新疆作物遗传改良与种质创新重点实验室新疆乌鲁木齐830052

醇酰基转移酶(AAT)可以催化乙酰辅酶A与萜烯醇类物质的结合,生成各类乙酸酯类化合物。为探明薰衣草AAT基因在酯类化合物合成中的调控作用,本研究以薰衣草品系杂花叶片为供试材料,利用反转录PCR技术克隆薰衣草AAT基因的cDNA序列,该cDNA... 详细信息

醇酰基转移酶(AAT)可以催化乙酰辅酶A与萜烯醇类物质的结合,生成各类乙酸酯类化合物。为探明薰衣草AAT基因在酯类化合物合成中的调控作用,本研究以薰衣草品系杂花叶片为供试材料,利用反转录PCR技术克隆薰衣草AAT基因的cDNA序列,该cDNA序列长度为1344 bp,其编码蛋白质由447个氨基酸组成,是非跨膜亲水性蛋白质,属于PLN02481超级家族;薰衣草AAT与黄色猴面花EgAAT亲缘关系最近,相似度为60.87%。AAT基因在苞叶中的表达量最低,在花瓣中的表达量最高;在花冠不同发育时期,该基因在盛开期表达量到达峰值。构建原核表达载体pET-28a-AAT,筛选了重组蛋白在大肠杆菌Transetta(DE3)中的最适诱导表达条件,诱导后获得的重组蛋白质相对分子质量为5.026×10^(4),重组蛋白以包涵体形式存在,具有将芳樟醇催化合成乙酸芳樟酯的生物活性。本研究结果为进一步验证薰衣草AAT基因在酯类化合物合成过程中的功能提供了基础。

关键词：薰衣草醇酰基转移酶基因(AAT) 克隆表达模式酶活性鉴定

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原位晶化法合成大孔-微孔MFI型分子筛

应用化工 2024年第1期53卷 25-30页

作者：朱绍林孙明慧刘湛余申吕佳敏李小云陈丽华武汉理工大学材料复合新技术国家重点实验室湖北武汉430070 武汉理工大学硅酸盐建筑材料国家重点实验室湖北武汉430070

使用单分散纳米级二氧化硅小球(500 nm)作为硅源和大孔模板,以四丙基氢氧化铵为微孔模板,通过“溶解-重结晶”过程原位形成大孔结构,得到大孔-微孔纯硅Silicate-1分子筛(MFI晶型),大孔孔径为150~350 nm,比表面积为350 m^(2)/g,总孔体积... 详细信息

使用单分散纳米级二氧化硅小球(500 nm)作为硅源和大孔模板,以四丙基氢氧化铵为微孔模板,通过“溶解-重结晶”过程原位形成大孔结构,得到大孔-微孔纯硅Silicate-1分子筛(MFI晶型),大孔孔径为150~350 nm,比表面积为350 m^(2)/g,总孔体积为0.24 cm^(3)/g。并探索了晶化时间、乙醇助剂、干胶干燥条件、微孔模板剂用量及大孔模板尺寸等合成条件对大孔-微孔纯硅Silicate-1分子筛晶化的影响。在此基础上,进一步在纯硅分子筛骨架中引入铝原子,得到大孔-微孔ZSM-5分子筛。

关键词：二氧化硅小球蒸汽辅助晶化原位晶化大孔-微孔结构 MFI型分子筛

Interfacial friction effects on sealing performances of elastomer packer

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Petroleum Science 2024年第3期21卷 2037-2047页

作者： Peng-Cheng Wang ming-hui Chen Jim Jenkinson Yong-Xin Song Li sun Department of Mechanical Engineering University of HoustonHoustonTX77024USA Guren Nanomaterials Suzhou215127JiangsuChina Department of Marine Engineering Dalian Maritime UniversityDalian116026LiaoningChina

Elastomer sealing performance is of critical importance for downhole tools application including the use of fracturing(Frac)plugs during multi-stage hydraulic *** practice sealing performances of such plugs are normally evaluated through pressure tests,and in numerical simulation studies,maximum contact stress,average contact stress and contact length data are used to determine sealing quality between a packer and *** previous studies,the impact of friction forces on sealing performance is often *** work aims to fill this knowledge gap in determining the influence of friction forces on elastomer packer sealing *** first determined the most appropriate constitutive hyperelastic model for the elastomers used in frac *** we compared analytical calculation results with Finite Element Analysis simulation using a simplified tubular geometry and showed the significant influences on interfacial friction on elastomer packer stress distribution,deformation,and contact stress after *** the demonstration of validity of FEA method,we conducted systematic numerical simulation studies to show how the interfacial friction coefficients can affect the maximum contact stress,average contact stress,contact stress distribution,and maximum mises stress for an actual packer used in plug *** addition,we also demonstrated how the groove in a packer can affect packer deformation and evolvement during setting with the consideration of interfacial *** study underscores the critical role that friction forces play in Frac plug performance and provides a new dimension for optimizing packer design by controlling interfacial interactions at the packer contact surfaces.

关键词： Elastomer seal Friction Sealing performance Contact stress

Synthesis,chemical bonding and reactivity of new medium-sized polyarsenides

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Chinese Chemical Letters 2024年第7期35卷 497-501页

作者： Xu-hui Yue Xiang-Wen Zhang hui-Min He Lei Qiao Zhong-ming sun State Key Laboratory of Element-Organic Chemistry Tianjin Key Lab for Institution Rare Earth Materials and ApplicationsSchool of Materials Science and EngineeringNankai UniversityTianjin 300350China Department of Physics Institute of Computational and Applied PhysicsTaiyuan Normal UniversityJinzhong 030619China

Gaining an understanding of the growth mechanism from single atoms to clusters and bulk materials continues to present a ***,it is important to explore the evolving trends of clusters in the structure and properties during the size *** this work,we report the synthesis and characterization of two medium-sized chain-like polyarsenic anions.[As_(21)]^(3-)represents a trimeric example of polyarsenic anion assembled through oxidative coupling of As_(7)^(3-)*** anion As_(18)^(4-)included in[As_(18)MO_(2)(CO)_(8)]^(4-)is regarded as formed by two realgar-type As_(8)subunits connected by a dinuclear AsAs *** As_(18)cluster was previously predicted by theory,and this is the first time successfully synthesized using wet chemistry ***,small-sized polyarsenides As_(2)^(2-)and As_(10)^(2-)were found in compound[K(18-crown-6)]_(3)[As_(10)]_(0.5)[As_(4){Mo(CO)_(3)}_(2)]_(0.5)·*** these,the former exhibits coordination with metal ***-crystal X-ray diffraction combined with quantum chemical calculations revealed the formation of double bonded As_(2)^(2-)stabilized by metal carbonyl *** work demonstrates a novel synthetic approach for the preparation of new polyarsenides and highlights their intriguing bonding characteristics,laying the foundation for the synthesis of such compounds and paving the way for their potential applications.

关键词： Polyarsenide Zintl anions Chain-like cluster DFT calculations AdNDP

Alisol B 23-acetate promotes white adipose tissue browning to mitigate high-fat diet-induced obesity by regulating mTOR-SREBP1 signaling

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Journal of Integrative Medicine 2024年第1期22卷 83-92页

作者： Lu-lu Han Xin Zhang hui Zhang Ting Li Yi-chen Zhao ming-hui Tian Feng-lei sun Bo Feng Department of Neurology Three The Fifth People’s Hospital of JinanJinan 250013Shandong ProvinceChina Department of Gastroenterology Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina The First Clinical Medical College Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of Geriatrics the First Affiliated Hospital of Shandong First Medical University(Shandong Provincial Qianfoshan Hospital)Jinan 250014Shandong ProvinceChina Chinese Medicine Culture and Literature Research Institute Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of General Medicine Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Department of Traditional Chinese Medicine the Second People’s Hospital of Haibei PrefectureZangzu Autonomous Prefecture of Haibei810300Qinghai ProvinceChina

Objective Obesity is a global health concern with management strategies encompassing bariatric surgery and anti-obesity drugs;however,concerns regarding complexities and side effects persist,driving research for more effective,low-risk *** promotion of white adipose tissue(WAT)browning has emerged as a promising ***,alisol B 23-acetate(AB23A)has demonstrated efficacy in addressing metabolic disorders,suggesting its potential as a therapeutic agent in obesity ***,in this study,we aimed to investigate the therapeutic potential of AB23A for mitigating obesity by regulating metabolic phenotypes and lipid distribution in mice fed a high-fat diet(HFD).Methods An obesity mouse model was established by administration of an *** and insulin metabolism were assessed via glucose and insulin tolerance *** size was determined using hematoxylin and eosin *** expression of browning markers in WAT was evaluated using Western blotting and quantitative real-time polymerase chain *** cage monitoring involved the assessment of various parameters,including food and water intake,energy metabolism,respiratory exchange rates,and physical ***,oil red O staining was used to evaluate intracellular lipid accumulation.A bioinformatic analysis tool for identifying the molecular mechanisms of traditional Chinese medicine was used to examine AB23A targets and associated signaling *** AB23A administration significantly reduced the weight of obese mice,decreased the mass of inguinal WAT,epididymal WAT,and perirenal adipose tissue,improved glucose and insulin metabolism,and reduced adipocyte ***,treatment with AB23A promoted the expression of browning markers in WAT,enhanced overall energy metabolism in mice,and had no discernible effect on food intake,water consumption,or physical *** 3T3-L1 cells,AB23A inhibited lipid accumulation,and both AB23A and rapamycin inhibited t

关键词： Obesity Alisol B 23-acetate Adipose tissue mTOR-SREBP1 High-fat diet

Single-wall carbon nanotube fiber non-woven fabrics with a high electrothermal heating response

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Nano Research 2024年第6期17卷 5621-5628页

作者： Xinyu Jiao Lele Xu Xinyang sun Chao Shi Peng-Xiang Hou Chang Liu hui-ming Cheng Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China Faculty of Materials Science and Engineering/Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Carbon nanotube(CNT)fibers have great promise for constructing multifunctional fabrics with high electrical conductivity,good electro-heating ability,excellent flexibility,and a low ***,the inter-fiber contacts in the fabric greatly reduce these advantages and limit their ***,a simple pressure-fusing method to fabricate single-wall CNT(SWCNT)fiber non-woven fabrics(NWFs)that are composed of interconnected SWCNT fibers with fused joints is reported,which have good flexibility,a low density of 0.46 g/cm^(3),a high electrical conductivity of 3.7×10^(5)S/m,and a record high specific electrical conductivity of 803(S·m^(2))/*** also showed excellent electrical heating ability,so that a temperature of~160℃was rapidly reached at a low voltage of 2 *** with their low density,the SWCNT fiber NWFs are promising for use as a heating unit for low temperature battery protection and de-icing applications.

关键词： carbon nanotube fiber nonwoven fabrics fusing electrothermal heating