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教师教学审美距离的内涵、作用及实现路径

教学与管理 2024年第7期 1-5页

作者：孙嘉蔓李如密南京师范大学课程与教学研究所南京210036

“教学审美距离”借鉴美学中的“审美距离”概念,是指教师在教学活动中与教学保持适当的距离,将教学作为审美对象,以观赏者的视角直面教学,促进自身教学经验嬗变深化,从而获得超越日常教学经验的美感体验。“教学审美距离”的作用贯穿... 详细信息

“教学审美距离”借鉴美学中的“审美距离”概念,是指教师在教学活动中与教学保持适当的距离,将教学作为审美对象,以观赏者的视角直面教学,促进自身教学经验嬗变深化,从而获得超越日常教学经验的美感体验。“教学审美距离”的作用贯穿于教学始终,有利于保障教学设计、课堂教学、教学评价、教学情感表达的有效性,重在通过“自知无知而求知”构建超越现实情境的意象世界,以无功利的审美态度感知教学,将教师的经验进行“悬置”等方式来探索其实现路径,以使教师获得更高层次的教学审美体验,从而取得更好的教学效果。

关键词：教学审美距离经验改造意象世界美感经验

Performance analysis of a photovoltaic/thermal system with lunar regolith-based thermal storage for the lunar base

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Science China(Technological Sciences) 2024年第4期67卷 1113-1123页

作者： sun WenGan ZHAO Bin PEI Yu SHI LingFeng HU MaoBin LI MuJun REN Xiao PEI Gang Deep Space Exploration Laboratory Hefei 230026China Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei 230026China Department of Mechanical and Aerospace Engineering University of California San DiegoLa JollaCA 92093USA Department of Precision Machinery and Precision Instrumentation University of Science and Technology of ChinaHefei 230026China College of New Energy China University of Petroleum(East China)Qingdao 266000China

Powering a moon base,especially keeping it warm during the long lunar night,is a big *** paper introduces a photovoltaic/thermal(PV/T)system incorporating regolith thermal storage to solve the challenge of power and heat provision for the lunar base *** vacuum of space around the moon helps this system by reducing heat *** the moon's daytime,the system not only generates electricity but also captures *** stored heat in the regolith is then used at night,reducing the amount of equipment we need to send from *** spectrally selective PV/T panels are designed to absorb a wide range of sunlight(0.3–2.5μm)while minimizing heat loss in the infrared range(3–30μm).Simulation results of the hybrid solar energy system indicate the average value of the overall efficiency is 45.9%,which relatively elevates 56.1%compared to the PV *** launch mass of the proposed PV/T system is only 8.4%of a traditional photovoltaic-lithium battery system with the same amount of energy *** the total specific energy of the proposed system is 7.3 kWh kg^(-1),while that of the photovoltaic-lithium battery system is about 0.3 kWh kg^(-1).In summary,this study proposes an alternative combined heat and electricity supply system for the lunar base,which can greatly reduce the launch mass and free up load for other scientific research equipment.

关键词： in-situ resource utilization(IRSU) regolith thermal storage photovoltaic/thermal(PV/T) spectral selectivity

楚国女性贵族的体质特征——以平顶山叶县辛庄一号战国楚墓为例

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文博 2024年第1期 90-96页

作者：李彦桢米科莱孙蕾河南省文物考古研究院河南郑州450000 平顶山市文物管理局河南平顶山467000

本文对平顶山叶县战国时期辛庄一号楚国贵族墓葬出土的一具人骨进行了体质人类学研究。辛庄一号墓主是一位60岁以上的女性,颅骨形态与曾侯乙墓女性陪葬者最相似。一系列牙病暗示墓主在幼年时期身体健康状况较差。仅出现于胸、颈部的退... 详细信息

本文对平顶山叶县战国时期辛庄一号楚国贵族墓葬出土的一具人骨进行了体质人类学研究。辛庄一号墓主是一位60岁以上的女性,颅骨形态与曾侯乙墓女性陪葬者最相似。一系列牙病暗示墓主在幼年时期身体健康状况较差。仅出现于胸、颈部的退行性关节炎,表明墓主生前未参与增加关节负荷的高强度运动,只是头颈部常年处于疲劳状态。下肢跪踞面及双手指骨明显的屈肌附着点,证明墓主生前长期跪坐,并可能将鼓瑟作为一项日常生活习惯。

关键词：叶县辛庄楚国贵族退行性关节炎跪踞面鼓瑟

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基于扩散算法的无下垂分布式储能控制

上海交通大学学报 2024年第6期58卷 836-845页

作者：米阳张浩杰钱翌明邢海军龚锦霞孙改平上海电力大学电气工程学院上海200090

针对线路阻抗不匹配及母线电压不一致时,下垂控制无法同时实现母线电压稳定及储能间功率精确分配的问题,提出一种基于扩散算法的无下垂分布式储能控制策略.首先,将扩散算法应用于直流微电网的分布式估计中获取全局平均量,同时将电压额... 详细信息

针对线路阻抗不匹配及母线电压不一致时,下垂控制无法同时实现母线电压稳定及储能间功率精确分配的问题,提出一种基于扩散算法的无下垂分布式储能控制策略.首先,将扩散算法应用于直流微电网的分布式估计中获取全局平均量,同时将电压额定值与平均电压的差值作为补偿项,用于恢复母线电压偏差.为了实现不同额定容量及不同荷电状态(SOC)的储能间功率精确分配,设计储能的标准功率并将其与平均标准功率的差值作为补偿项,用于储能间SOC的均衡.最后,利用RT-LAB平台搭建模型,分别验证4种不同工作模式下所设计控制策略的有效性.实验结果表明,所提控制策略可实现孤岛直流微电网母线电压恢复及储能功率的精确分配.

关键词：直流微电网扩散算法无下垂控制分布式控制功率精确分配

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钛铝系合金的非等温氧化特性

材料工程 2024年第5期52卷 26-33页

作者：欧阳佩旋陈航孙若晨李培杰弭光宝清华大学新材料国际研发中心北京100084 北方工业大学机械与材料工程学院北京100144 辽宁工程技术大学机械工程学院辽宁阜新123000 中国航发北京航空材料研究院先进钛合金重点实验室北京100095

采用TGA/DSC同步热分析实验,SEM和EPMA表征及理论计算等方法对TiAl和Ti3Al合金在纯氧气氛下1450~1570℃的非等温氧化行为进行研究。结果表明:当氧化温度高于TiAl合金熔点时,TiAl合金熔体表面形成连续、致密的Al_(2)O_(3)阻氧层;熔体中Al... 详细信息

采用TGA/DSC同步热分析实验,SEM和EPMA表征及理论计算等方法对TiAl和Ti3Al合金在纯氧气氛下1450~1570℃的非等温氧化行为进行研究。结果表明:当氧化温度高于TiAl合金熔点时,TiAl合金熔体表面形成连续、致密的Al_(2)O_(3)阻氧层;熔体中Al与O反应的吉布斯自由能比Ti,Cr和Nb低50~150 kJ·mol^(-1),TiAl合金熔体中Al原子的扩散系数(D)约为Ti原子的1.7倍,Al原子不断扩散到熔体表面,且优先与O反应形成连续、致密的Al_(2)O_(3)层;Al_(2)O_(3)阻氧层阻隔氧和金属离子向基体内外扩散,且TiAl合金熔化吸热,降低基体温度,减缓氧化速率,使TiAl合金在1450~1570℃范围的抗非等温氧化性优于Ti3Al合金。

关键词： TiAl合金非等温氧化氧化机理氧化动力学着火

瓜蒌- 薤白调节肠道菌群治疗冠心病模型大鼠的作用及机制

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中国组织工程研究 2025年第5期29卷 917-927页

作者：孙广瀚谢珍聪孙咪徐洋郭栋山东中医药大学第一临床医学院山东省济南市250014 山东中医药大学教师发展中心山东省济南市250355 山东中医药大学药物研究院山东省济南市250355

背景:基于网络药理学方法发现瓜蒌-薤白药对中主要生物活性化合物对冠心病有多功能作用;然而其治疗冠心病的机制尚未得到充分阐释。目的:探讨瓜蒌-薤白通过调节肠道微生物的组成改善冠心病的作用及机制。方法:40只SD大鼠按随机数字表法... 详细信息

背景:基于网络药理学方法发现瓜蒌-薤白药对中主要生物活性化合物对冠心病有多功能作用;然而其治疗冠心病的机制尚未得到充分阐释。目的:探讨瓜蒌-薤白通过调节肠道微生物的组成改善冠心病的作用及机制。方法:40只SD大鼠按随机数字表法分为空白组、模型组、阳性药组、药对组,除空白组外,其余大鼠连续灌胃脂肪乳剂和注射垂体后叶素制备冠心病大鼠模型。造模后模型组大鼠灌胃蒸馏水(10 mL/kg)进行对照,阳性药组大鼠每日灌胃辛伐他汀4 mg/kg,药对组每日灌胃瓜蒌-薤白7.56 g/kg,各组大鼠给药均为14 d。观察大鼠心电图、心肌病理及血脂变化,并通过16S rDNA测序技术研究大鼠经干预后肠道微生物结构。结果与结论:①心电图结果显示模型组ST抬高;阳性药组与药对组心电图无明显问题。②与空白组相比,模型组总胆固醇、三酰甘油、低密度脂蛋白胆固醇水平均显著增高(P0.05),Simpson指数降低(Pmicutes、Muribaculaceae_norank等相对丰度降低;与阳性药相比,药对组Desulfobacterota、Bacteroides等相对丰度升高,Firmicutes、[Eubacterium]_coprostanoligenes_group_norank等相对丰度降低;LEfSe结果发现差异显著的种群富集于药对组最多,其次是空白组、阳性药组,模型组最少。⑥结论:瓜蒌-薤白可以通过调节肠道菌群改善冠心病的发生发展,为进一步研发瓜蒌-薤白提供新的启示。

关键词： “瓜蒌-薤白”药对 16S rDNA 冠心病肠道菌群大鼠

Inhalation of taraxasterol loaded mixed micelles for the treatment of idiopathic pulmonary fibrosis

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Chinese Chemical Letters 2024年第8期35卷 475-480页

作者： Tong Zhang Chao sun Shubin Yang Zimin Cai Sifeng Zhu Wendian Liu Yun Luan Cheng Wang Key Laboratory of Marine Drugs Chinese Ministry of EducationSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China Central Research Laboratory Department of General Surgerythe Second Hospital of Shandong UniversityJi’nan 250033China Laboratory for Marine Drugs and Bioproducts Pilot National Laboratory for Marine Science and TechnologyQingdao 266237China Orthopedics Dept.1 Rushan people’s hospitalRushan 264500China Department of Cardiology the Second Hospital of Shandong UniversityJi’nan 250033China

Idiopathic pulmonary fibrosis(IPF)is a chronic and fatal lung disease characterized by pulmonary inflam-mation,oxidative stress,and excessive extracellular matrix(ECM)*** anti-fibrotic drugs for IPF treatment in the clinic lack selectivity and demonstrate unsatisfactory efficacy,highlighting the urgent necessity for a novel therapeutic ***(TA),which has biological activities against lung injury induced by various factors,is a potential anti-IPF drug due to its anti-inflammatory,antiox-idant and lung-protective ***,the protective effect of TA on IPF has not been confirmed,and its clinical application is limited due to its poor aqueous *** this study,we demonstrated that TA could inhibit epithelial-mesenchymal transition(EMT)and migration of A549 cells by inhibiting the transforming growth factor-β1(TGF-β1)/Smad signaling *** improve the aqueous solubility and pulmonary administration performance of TA,we prepared TA loaded methoxy poly(ethylene glycol)-poly(d,l-lactide)(mPEG-PLA)/d-α-tocopheryl polyethylene glycol succinate(TPGS)mixed polymeric mi-celles(TA-PM).Then a microSprayer^(R) Aerosolizer was used to deliver TA-PM once every two days for three weeks to evaluate their therapeutic effects on bleomycin(BLM)-induced IPF *** results demonstrated that inhaled TA-PM significantly inhibited BLM-induced inflammation,oxidative stress and fibrosis in lung ***,TA-PM exhibited high pulmonary deposition and retention by pul-monary administration,along with a favorable safety ***,this study emphasizes the potential of inhaled TA-PM as a promising treatment for IPF,providing a new opportunity for their clinical appli-cation.

关键词： Taraxasterol Idiopathic pulmonary fibrosis mixed polymeric micelles Pulmonary administration Bleomycin

LncRNA CCRR maintains Ca^(2+)homeostasis against myocardial infarction through the FTO-SERCA2a pathway

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Science China(Life Sciences) 2024年第8期67卷 1601-1619页

作者： Hua Yang Lina Xuan Shengjie Wang Huishan Luo Xiaomeng Duan Jianjun Guo Shijia Cui Jieru Xin Junwei Hao Xiufang Li Jun Chen Feihan sun Xiaolin Hu Siyun Li Ying Zhang Lei Jiao Baofeng Yang Lihua sun Department of Pharmacology Harbin Medical University(State Key Laboratory of Frigid Zone Cardiovascular Diseasethe State-Province Key Laboratories of Biomedicine-Pharmaceutics of ChinaKey Laboratory of Cardiovascular ResearchMinistry of EducationJoint International Research Laboratory of Cardiovascular Medicine ResearchMinistry of EducationChina)College of PharmacyHarbin Medical UniversityHarbin 150081China

Cardiac conduction regulatory RNA(CCRR)has been documented as an antiarrhythmic lncRNA in our earlier *** study aimed to evaluate the effects of CCRR on SERCA2a and the associated Ca^(2+)homeostasis in myocardial infarction(mi).Overexpression of CCRR via AAV9-mediated delivery not only partially reversed ischemia-induced contractile dysfunction but also alleviated abnormal Ca^(2+)homeostasis and reduced the heightened methylation level of SERCA2a following *** effects were also observed in CCRR overexpressing transgenic mice.A conserved sequence domain of CCRR mimicked the protective function observed with the full ***,silencing CCRR in healthy mice led to intracellular Ca^(2+)overloading of *** increased SERCA2a protein stability by upregulating FTO *** direct interaction between CCRR and FTO protein was characterized by RNA-binding protein immunoprecipitation(RIP)analysis and RNA pulldown *** of NFATc3 was identified as an upstream mechanism responsible for CCRR downregulation in *** study demonstrates that CCRR is a protective lncRNA that acts by maintaining the function of FTO,thereby reducing the m^(6)A RNA methylation level of SERCA2a,ultimately preserving calcium homeostasis for myocardial contractile function in ***,CCRR may be considered a promising therapeutic strategy with a beneficial role in cardiac pathology.

关键词： CCRR calcium homeostasis FTO myocardial infarction SERCA2a

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城轨交通牵引供电系统电流与功率追踪研究

中国电机工程学报 2024年第6期44卷 2270-2278,I0015页

作者：米佳雨杨中平钟志宏林飞孙凯琦毛润前北京交通大学电气工程学院北京市海淀区100044

对于包含多个变电站的城轨牵引供电系统,在多车协同运行场景下,变电站、牵引列车、制动列车之间存在着复杂的能量交互。现有的潮流计算方法只关注于得到某时刻下各支路电流的大小,并未深入分析系统中各源(变电站和制动列车)与负荷(牵引... 详细信息

对于包含多个变电站的城轨牵引供电系统,在多车协同运行场景下,变电站、牵引列车、制动列车之间存在着复杂的能量交互。现有的潮流计算方法只关注于得到某时刻下各支路电流的大小,并未深入分析系统中各源(变电站和制动列车)与负荷(牵引列车和线路电阻)之间定量的电流及功率分配关系。该文基于电路理论,对城轨牵引供电系统中的电流分配情况进行上游追踪与下游追踪,定量表征源电流与负荷电流之间的比例关系;基于电流追踪的结果,对城轨牵引供电系统的功率分配进行上游追踪与下游追踪,得到源功率与负荷功率之间的具体分配系数。最后,通过算例分析验证所提潮流追踪算法的有效性和正确性。潮流追踪直观定量地展示了系统的功率流动路径,为后续优化储能系统容量配置和多储能系统间的协调控制提供理论支撑。

关键词：城市轨道交通电流追踪功率追踪节点电压方程上游追踪下游追踪