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Graphene-Based Coronal Hybrids for Enhanced Energy Storage

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Energy Material Advances 2021年第1期2021卷 218-232页

作者： Karthik Kiran Sarigamala Shobha Shukla Alexander Struck sumit Saxena Centre for Research in Nanotechnology and Science Indian Institute of Technology Bombay400076MumbaiIndia Nanostructures Engineering and Modelling Laboratory Department of Metallurgical Engineering and Materials ScienceIndian Institute of Technology Bombay400076MumbaiIndia Faculty of Technology and Bionics Rhein-Waal University of Applied SciencesKleveGermany 47533

Functional materials with designer morphologies are anticipated to be the next generation materials for energy storage *** this manuscript,we have developed a holistic approach to enhance the surface area and hence the properties of nanostructures by synthesizing coronal nanohybrids of *** nanohybrids provide distinctive advantages in terms of performance and stability over vertically stacked nanocomposites reported in *** double hydroxide materials self-assembled as coronal lamellae on graphene shells have been synthesized and systematically *** coronal nanohybrids result in about a threefold increase in energy storage capacity as compared to their traditionally synthesized nanocomposite *** 3D graphene-based nanofibrils in the synthesized coronal nanohybrids provide mechanical support and connect the nodes of the double hydroxide lattices to inhibit *** morphologies such as coronal nanostructures increase the interaction surface of the nanostructure *** an approach is also expected to bring a paradigm shift in development of functional materials for various applications such as sensors,energy storage,and catalysis.

关键词： hydroxide hence shells

Hereditary fructose intolerance: A comprehensive review

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World Journal of Clinical Pediatrics 2022年第4期11卷 321-329页

作者： sumit Kumar Singh Moinak Sen Sarma Department of Pediatrics Sri Aurobindo Medical College and PGIIndore 453555Madhya PradeshIndia Department of Pediatric Gastroenterology Sanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014India

Hereditary fructose intolerance(HFI)is a rare autosomal recessive inherited disorder that occurs due to the mutation of enzyme aldolase B located on chromosome 9q22.3.A fructose load leads to the rapid accumulation of fructose 1-phosphate and manifests with its downstream *** commonly children are affected with gastrointestinal symptoms,feeding issues,aversion to sweets and *** manifestations include an asymptomatic increase of transaminases,steatohepatitis and rarely liver *** involvement usually occurs in the form of proximal renal tubular acidosis and may lead to chronic renal *** confirmation,a genetic test is favored over the measurement of aldolase B activity in the liver biopsy *** crux of HFI management lies in the absolute avoidance of foods containing fructose,sucrose,and sorbitol(FSS).There are many dilemmas regarding tolerance,dietary restriction and occurrence of *** with HFI who adhere strictly to FSS free diet have an excellent prognosis with a normal *** review attempts to increase awareness and provide a comprehensive review of this rare but treatable disorder.

关键词： Hereditary Fructose Intolerance Children Liver Steatohepatitis Aldolase

Protease inhibitors:recent advancement in its usage as a potential biocontrol agent for insect pest management

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Insect Science 2020年第2期27卷 186-201页

作者： Sujata Singh Archana Singh sumit Kumar Pooja Mittal Indrakant K.Singh Molecular Biology Research Laboratory Department of ZoologyDeshbandhu CollegeUniversity of DelhiKalkajiNew DelhiIndia Department of Botany Hans Raj CollegeUniversity of DelhiDelhiIndia

Plant derived protease inhibitors(PIs)are a promising defensin for crop im-provement and insect pest *** agronomist made significant efforts in utilizing PIs for managing insect *** potentials of PIs are still *** ability to compensate nutrient starvation induced by dietary PI feeding using different strategies,that is,overexpression of PI-sensitive protease,expression of PI-insensitive proteases,degradation of PI,has made this innumerable collection of PIs worthless.A practical challenge for agronomist is to identify potent PI candidates,to limit insect compensatory responses and to elucidate insect compensatory and resistance mechanisms activated upon *** knowledge could be further efficiently utilized to identify potential targets for RNAi-mediated pest *** vital genes of insects could be functionally anno-tated using the advanced gene-editing technique,CRISPR/*** research is exploiting different in silico and modern molecular biology techniques to utilize PIs in controlling insect pests *** review is structured to update recent advancements in this field,along with is chronological background.

关键词： gene stacking insect pest management PI transgenic proteases protease inhibitors transplastomic

Growing Economic Interdependence of China and the Gulf Cooperation Council

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China & World Economy 2008年第2期16卷 109-124页

作者： Michael Thorpe sumit Mitra College of Graduate Studies University of WollongongDubaiUnited Arab Emirates College of Graduate Studies University of WollongongDubaiUAE

The six nations of the Gulf Cooperation Council （GCC） have approximately 40percent of total proven oil reserves as well as 23 percent of the world＇s gas reserves. Although rising oil revenues have led to greater outward investment flows, there is also a growing need for significant expansion of the domestic energy sector＇s capacity. Meanwhile, China＇s sustained economic boom has resulted in China emerging as the world＇s second largest consumer and importer o foil, with close to 40percent of its import demand presently sourced from the GCC. This share will grow significantly in the future. Commercial relations between the GCC and China have to date been dominated by energy-related bilateral investment flows and China＇s oil imports. Although this will continue to be a central feature, trade and investment links in non-energy areas will further broaden and deepen the relationship. China ＇s relationship with the USA in terms of energy is also emerging as a major issue. Rather than being competitors, a mutual dependence on stable and secure supplies from the GCC highlights the need for a cooperative relationship.

关键词： China Gulf Cooperation Council economic interdependence oil

An Efficient Hybrid PAPR Reduction for 5G NOMA-FBMC Waveforms

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Computers, Materials & Continua 2021年第12期69卷 2967-2981页

作者： Arun Kumar Sivabalan Ambigapathy Mehedi Masud Emad Sami Jaha sumit Chakravarty Kanchan Sengar Department of Electronics and Communication Engineering JECRC UniversityJaipur303905India Center for System Design Chennai Institute of TechnologyIndia Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Science Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddahSaudi Arabia Department of Electrical and Computer Engineering Kennesaw State UniversityGAUSA

The article introduces Non-Orthogonal Multiple Access(NOMA)and Filter Bank Multicarrier(FBMC),known as hybrid waveform(NOMAFBMC),as two of the most deserving contenders for fifth-generation(5G)*** spectrum access and clampdown of spectrum outflow are unique characteristics of hybrid *** compare the spectral efficiency of Orthogonal Frequency Division Multiplexing(OFDM),FBMC,NOMA,and *** is seen that the hybrid waveform outperforms the existing *** to Average Power Ratio(PAPR)is regarded as a significant issue in multicarrier *** combination of Selective Mapping-Partial Transmit Sequence(SLM-PTS)is an effective way to minimize large peak power *** SLM,PTS,and SLM-PTS procedures are applied to the NOMA-FBMC *** hybrid structure is applied to the existing ***,the correlated factors like Bit Error Rate(BER)and Computational Overhead(CO)are studied and computed for these *** outcome of the work reveals that the NOMA-FBMC waveform coupled with the SLM-PTS algorithm offers superior performance as compared to the prevailing systems.

关键词： 5G NOMA-FBMC SLM-PTS PAPR BER OFDM

Differential methylation landscape of pancreatic ductal adenocarcinoma and its precancerous lesions

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Hepatobiliary & Pancreatic Diseases International 2020年第3期19卷 205-217页

作者： Akash Bararia Subhankar Dey sumit Gulati Supriyo Ghatak Shibajyoti Ghosh Sudeep Banerjee Nilabja Sikdar Human Genetics Unit Indian Statistical InstituteKolkataIndia Department of Zoology New Alipore CollegeUniversity of CalcuttaKolkataIndia Department of Gastroenterological Surgery Calcutta Medical Research InstituteKolkataIndia Department of General Surgery Medical College and HospitalKolkataIndia Department of Gastrointestinal Surgery Tata Medical CenterRajarhatKolkataIndia

Background:Pancreatic cancer is one of the most lethal diseases with an incidence almost equal to the *** addition to having genetic causes,cancer can also be considered an epigenetic *** methylation is the premier epigenetic modification and patterns of aberrant DNA methylation are recognized to be a common hallmark of human *** the multistage carcinogenesis of pancreas starting from precancerous lesions to pancreatic ductal adenocarcinoma(PDAC),the epigenetic changes play a significant *** sources:Relevant studies for this review were derived via an extensive literature search in Pub Med via using various keywords such as pancreatic ductal adenocarcinoma,precancerous lesions,methylation profile,epigenetic biomarkers that are relevant directly or closely associated with the concerned area of our *** literature search was intensively done considering a time frame of 20 years(1998–2018).Result:In this review we have highlighted the hypermethylation and hypomethylation of the precancerous PDAC lesions(pancreatic intra-epithelial neoplasia,intraductal papillary mucinous neoplasm,mucinous cystic neoplasm and chronic pancreatitis)and PDAC along with the potential *** have also achieved the early epigenetic driver that leads to progression from precancerous lesions to PDAC.A bunch of epigenetic driver genes leads to progression of precancerous lesions to PDAC(pp ENK,APC,p14/5/16/17,h MLH1 and MGMT)are also *** summarized the importance of these observations in therapeutics and diagnosis of PDAC hence identifying the potential use of epigenetic biomarkers in epigenetic targeted *** inactivation occurs by hypermethylation of Cp G islands in the promoter regions of tumor suppressor *** listed all hyper-and hypomethylation of Cp G islands of several genes in PDAC including its precancerous ***:The concept of the review would help to understand their biological effects,and to determine

关键词： Pancreatic cancer Methylation CpG islands Epigenetic Biomarkers Precancerous lesions

Tiletamine/zolazepam and dexmedetomidine with tramadol provide effective general anesthesia in rats

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Animal Models and Experimental Medicine 2021年第1期4卷 40-46页

作者： Vudhiporn Limprasutr Patrick Sharp Katechan Jampachaisri Cholawat Pacharinsak sumit Durongphongtorn Department of Pharmacology and Physiology Faculty of Pharmaceutical SciencesChulalongkorn UniversityBangkokThailand Research Clusters:Preclinical Toxicity and Efficacy Assessment of Medicines and Chemicals Chulalongkorn UniversityBangkokThailand Animal Resources Centre MurdochWAAustralia Department of Mathematics Faculty of SciencesNaresuan UniversityPhitsanulokThailand Department of Comparative Medicine School of MedicineStanford UniversityStanfordCAUSA Department of Veterinary Surgery Faculty of Veterinary ScienceChulalongkorn UniversityBangkokThailand

Background:Tiletamine/zolazepam is a dissociative anesthetic combination commonly used in small animals but information is limited in *** alpha-2 agonist,dexmedetomidine,has gained popularity in laboratory animal *** is a weak opioid mu *** aim of this study was to assess whether the tiletamine/zolazepam/dexmedetomidine(ZD)combination effectively provides a surgical anesthesia plane comparable to tiletamine/zolazepam/dexmedetomidine with tramadol(ZDT)in a minor procedure in ***:Rats were induced with ZD or *** the loss of paw withdrawal,a small incision was made on the rats’left thighs as a surgical *** were maintained under a surgical anesthesia plane by assessing the loss of the paw withdrawal reflex for 45 minutes,then atipamezole was *** anesthesia parameters included:(a)physiological parameters-pulse rate(PR),respiratory rate(RR),tissue oxygen saturation(%SpO 2),and body temperature;(b)duration parameters-induction time,onset and duration of surgical anesthesia plane,onset of recovery,and recovery ***:PR was significantly lower at 10 minutes in ZD and 5 minutes in ZDT *** difference was observed for RR,%SpO 2,and body ***,there were no differences for duration parameters:induction time was less than 3 minutes;onset and duration of surgical anesthesia plane were approximately 5 and 45 minutes,respectively;onset of recovery(time to move)was 51 minutes;and recovery time was 52 minutes,***:These data suggest the ZD combination provides a surgical anesthesia plane comparable to ZDT in a rat incisional pain model.

关键词： anesthesia dexmedetomidine rats tiletamine tramadol

Activity of Angiogenesis Inhibitors in Metastatic Epithelioid Hemangioendothelioma:A Case Report

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Clinical oncology and cancer researeh 2012年第2期9卷 133-136页

作者： sumit Gaur Alireza Torabi Thomas I O'Neill Divisions of Hematology-Oncology Texas Tech University Health Science Center Divisions of Pathology Texas Tech University Health Science Center Divisions of Radiology Texas Tech University Health Science Center

This report describes a patient with metastatic epithelioid hemangioendothelioma treated with bevacizumab and nanoparticle albumin-bound *** treatment was well tolerated and led to the stabilization of an aggressive variant of the disease. This case report is the first one that describes the activity of the combination of chemotherapy and bevacizumab in epithelioid *** describing the activity of bevacizumab and other agents(thalidomide,lenalidomide,and interferon) believed to possess anti-angiogenic activities is also reviewed.

关键词： hemangioendothelioma angiogenesis inhibitors nab-paclitaxel bevacizumab

Savings,investment,and growth in Nepal:an empirical analysis

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Financial Innovation 2019年第1期5卷 679-691页

作者： Aadersh Joshi sumit Pradhan Jagadish Prasad Bist Global College International affiliated to Midwestern University KathmanduNepal Uniglobe College affiliated to Pokhara University KathmanduNepal The British College affiliated to University of the West of England BristolUKKathmanduNepal

This study analyzes the relationship between savings,investment,and economic growth in Nepal over 1975–*** structural breaks in the variables have been accounted for using the(Zivot and Andrews’s,J Bus Econ Stat 10:251–2701992)unit root test along with(Gregory and Hansen’s,Oxf Bull Econ Stat 58:555–560,1996)cointegration *** ARDL approach to cointegration in the presence of structural breaks has also been utilized to analyze the long-and short-run dynamics of savings,investment,and growth in *** results show structural breaks in the real GDP per capita during 2001 when the Royal Massacre and a state of emergency have taken place in *** allowing for this structural break,evidence of a cointegration relationship amongst savings,investment,and economic growth was *** estimates of the ARDL approach suggest that investment has a significant and positive impact on economic ***,gross domestic savings have a negative impact on growth in the long *** results clearly show weaknesses of the economy in mobilizing savings into productive sectors.

关键词： Savings Investment Economic Growth Structural Break ARDL Model