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Development and characterization of ethylcellulose based microsphere for sustained release of nifedipine

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Journal of Pharmaceutical Analysis 2016年第5期6卷 341-344页

作者： Patitapabana Parida Subash Chandra Mishra subhashree Sahoo Ajit behera Bibhukalyan Prasad Nayak Department of Biotechnology and Medical Engineering NIT Rourkela Odisha 769008 India Department of Metallurgical and Materials Engineering NIT Rourkela Odisha 769008 India Department of Pharmaceutics Kanakmanjari Institute of Pharmaceutical Sciences Rourkela Odisha 769015 India Department of Metallurgical and Materials Engineering IIT Kharagpur West Bengal 721302 India

This article introduced the work of ethylcellulose based polymeric microsphere loaded with nifedipine for reduction in frequency of administration with low solubility in aqueous medium and high rate of absorption in the stomach. The non-aqueous polymeric suspension was put dropwise into an aqueous medium containing polyvinyl alcohol as a surfactant for the synthesis of microsphere by solvent evaporation. The microspheres were characterized by different techniques, namely, XRD, SEM, and NMR. The formation of microspheres was confirmed by SEM. XRD analysis revealed the semi-crystallinity nature of microspheres. The NMR study indicated the presence of hetero-aromatic nucleus in the microsphere.

关键词： Nifedipine Microsphere Solvent evaporation Sustained release

Estimation of carbon pools in secondary tropical deciduous forests of Odisha,India

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Journal of Forestry Research 2021年第2期32卷 663-673页

作者： subhashree Pattnayak M.Kumar N.K.Dhal Sudam C.Sahu Department of Life Sciences Sambalpur UniversitySambalpurOdisha 768019India Environment and Sustainability Department CSIR-IMMTBhubaneswarOdisha 751013India Department of Botany North Orissa UniversityBaripadaOdisha 757003India

Secondary tropical forests sequester atmospheric CO 2 at relatively faster rates in vegetation and in soil than old-growth primary *** understanding of biomass and carbon stocks in different plant functional types of these forests is ***,diversity,composition,soil features and carbon stocks in six distinct plant functional types,namely:Moist Mixed-Deciduous Forest,Peninsular Sal Forest(PSF),Semi-Evergreen Forest(SEF),Planted Teak Forest,Bamboo Brakes(BB),and Degraded Thorny Shrubby Forest were quantified as secondary tropical deciduous forests of the Chandaka Wildlife Sanctuary,Eastern Ghats of Odisha,***-one species≥10 cm Girth at breast height(GBH)were recorded,belonging to 38 families and 65 ***-ground biomass carbon and soil organic carbon ranged from 2.1–72.7 Mg C ha^(−1) and 20.6–67.1 Mg C ha^(−1),respectively,among all plant functional *** organic carbon and important value index were positively correlated with above-ground biomass *** carbon allocation was in SOC pool(51–91%),followed by the above-ground biomass pool(9–52%),indicating SOC is one of the major carbon sinks in secondary dry *** results highlight the importance of secondary tropical deciduous forests in biodiversity conservation and ecological importance in reducing greenhouse gases.

关键词： Chandaka wildlife Sanctuary Diversity indices Soil organic carbon Above-ground biomass carbon Correlation study

Detection of Diabetic Retinopathy from Retinal Images Using DenseNet Models

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Computer Systems Science & Engineering 2023年第4期45卷 279-292页

作者： R.Nandakumar P.Saranya Vijayakumar Ponnusamy subhashree Hazra Antara Gupta Department of ECE K S R Institute for Engineering and TechnologyTiruchengode637215India Department of Computer Science and Engineering SRM Institute of Science and TechnologyChennai603203India Department of Electronics and Communication and Engineering SRM Institute of Science and TechnologyChennai603203India

A prevalent diabetic complication is Diabetic Retinopathy(DR),which can damage the retina’s veins,leading to a severe loss of *** treated in the early stage,it can help to prevent vision *** since its diagnosis takes time and there is a shortage of ophthalmologists,patients suffer vision loss even before ***,early detection of DR is the necessity of the *** primary purpose of the work is to apply the data fusion/feature fusion technique,which combines more than one relevant feature to predict diabetic retinopathy at an early stage with greater *** procedures for diabetic retinopathy analysis are fundamental in taking care of these *** profound learning for parallel characterization has accomplished high approval exactness’s,multi-stage order results are less noteworthy,especially during beginning phase *** Connected Convolutional Networks are suggested to detect of Diabetic Retinopathy on retinal *** presented model is trained on a Diabetic Retinopathy Dataset having 3,662 images given by *** results suggest that the training accuracy of 93.51%0.98 precision,0.98 recall and 0.98 F1-score has been achieved through the best one out of the three models in the proposed *** same model is tested on 550 images of the Kaggle 2015 dataset where the proposed model was able to detect No DR images with 96%accuracy,Mild DR images with 90%accuracy,Moderate DR images with 89%accuracy,Severe DR images with 87%accuracy and Proliferative DR images with 93%accuracy.

关键词： Convolutional Neural Networks vision loss pathogenic blood vessels DenseNet AlexNet ResNet

Separation of hematite from banded hematite jasper(BHJ) by magnetic coating

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Journal of Central South University 2015年第2期22卷 437-444页

作者： subhashree Singh H.Sahoo S.S.Rath B.B.Palei B.Das CSIR-Institute of Minerals and Materials Technology

The separation of iron oxide from banded hematite jasper(BHJ) assaying 47.8% Fe, 25.6% Si O2 and 2.30%Al2O3 using selective magnetic coating was studied. Characterization studies of the low grade ore indicate that besides hematite and goethite,jasper, a microcrystalline form of quartzite, is the major impurity associated with this ore. Beneficiation by conventional magnetic separation technique could yield a magnetic concentrate containing 60.8% Fe with 51% Fe recovery. In order to enhance the recovery of the iron oxide minerals, fine magnetite, colloidal magnetite and oleate colloidal magnetite were used as the coating material. When subjected to magnetic separation, the coated ore produces an iron concentrate containing 60.2% Fe with an enhanced recovery of56%. The AFM studies indicate that the coagulation of hematite particles with the oleate colloidal magnetite facilitates the higher recovery of iron particles from the low grade BHJ iron ore under appropriate conditions.

关键词： banded hematite jasper ore selective coating oleate colloidal magnetite magnetic separation atomic force microscopy

A comprehensive review on energy storage in hybrid electric vehicle

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Journal of Traffic and Transportation Engineering(English Edition) 2021年第5期8卷 621-637页

作者： Shrey Verma Shubham Mishra Ambar Gaur Subhankar Chowdhury subhashree Mohapatra Gaurav Dwivedi Puneet Verma Energy Centre Maulana Azad National Institute of TechnologyBhopal 462007India School of Earth and Atmospheric Sciences Queensland University of TechnologyBrisbane 4001Australia

The sharp inclination in the emissions from conventional vehicles contribute to a significant increase in environmental issues,besides the energy crises and low conversion efficiency leads to the evolution of electric vehicles(EV).Hybrid electric vehicles(HEV) have efficient fuel economy and reduce the overall running cost,but the ultimate goal is to shift completely to the pure electric *** this,the main obstruction of HEV is energy storage *** EV requires high specific power(W/kg) and high specific energy(W$h/kg) to increase the distance travelled and reduce the time required for *** main focus of this paper is on the energy sources as these are the main components in EVs towards making them eco-friendly and *** topologies of EV technology such as HEVs,plug-in HEVs,and many more have been *** topologies of EVs are based on the diverse combination of batteries,fuel cells,super-capacitor,flywheels,regenerative braking systems,which are used as energy sources and energy storage devices.

关键词： Electric vehicle Energy storage Battery electric vehicle Hybrid electric vehicles

Quantification of browning in apples using colour and textural features by image analysis

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Food Quality and Safety 2017年第3期1卷 221-226页

作者： Srinivasagan N.subhashree S.Sunoj Jun Xue Ganesh C.Bora Agricultural and Biosystems Engineering North Dakota State UniversityFargoNorth DakotaUSA Guelph Food Research Center Agriculture and Agri-Food CanadaOntarioCanada Agricultural and Biological Engineering Mississippi State UniversityMississippiUSA

This study analyses the effect of browning through image analysis based on colour and textural features in fresh-cut apple slices.A computer vision system(CVS)was developed for image acquisition,which consisted of a digital camera and a florescent lamp source for illumination with a contrasting *** CVS was calibrated using standard colour values and a model was developed by artificial neural network *** varieties of apples such as Honey crisp,Granny Smith,and Golden Delicious were used for the *** apples were freshly cut and subjected to image *** colour features(L*,browning index,hue,and colour change)and textural features(entropy,contrast,and homogeneity)were analysed from the acquired *** varieties Honey Crisp and Granny Smith did undergo browning within 120 min,whereas Golden delicious did not brown *** study concluded that colour and textural features were important decision features for detecting browning in apples through image analysis.

关键词： apple browning colour calibration image analysis textural features

Carbon Nanoparticle Exerts Positive Growth Effects with Increase in Productivity by Down-Regulating Phytochrome B and Enhancing Internal Temperature in Rice

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Rice science 2021年第3期28卷 289-300,I0026,I0028页

作者： Madhusmita PANIGRAHY subhashree DAS Yugandhar POLI Pratap Kumar SAHOO Khushbu KUMARI Kishore C.S.PANIGRAHI School of Biological Sciences National Institute of Science Education and Research(Homi Bhabha National Institute)Odisha 752050India Biofuel&Bioprocessing Research Center Institute of Technical Education and ResearchSiksha‘O’Anusandhan Deemed to be UniversityOdisha 751001India Indian Institute of Rice Research Rajendra NagarHyderabad 500030India School of Physical Science National Institute of Science Education and Research(Homi Bhabha National Institute)Odisha 752050India Center for Interdisciplinary Science National Institute of Science Education and Research(Homi Bhabha National Institute)Odisha 752050India Faculty of Biology and Biotechnology Ruhr University BochumBochum 44780Germany

The effects of carbon nanoparticle(CNP)on rice variety Swarna(MTU7029)were *** induced effects similar to shade avoidance response(SAR)of Arabidopsis,with increase in shoot length,root length,root number,cotyledon area,chlorophyll content and total sugar content in rice *** mature plants,CNP treatment resulted increase in plant height,number of productive tillers per plant,normalized difference vegetation index,quantum yield and root growth.A total of 320 mg of CNP per plant administered in four doses resulted in improved grain traits such as filled grain rate,100-grain weight,grain length/width ratio,hulling rate,milling rate and head rice *** from the CNP-treated plants showed increase in amylose,starch and soluble sugar contents compared to ***,CNP treatment showed an average of 17.5%increase in yield per *** investigation to the molecular mechanism behind CNP induction of SAR,a significant downregulation of phytochrome B transcript was *** in perception of red wavelengths led to responses similar to *** in plant’s internal temperature by 0.5ºC±0.1ºC was recorded after CNP *** suggest that the internalized CNP aggregates may serve to absorb extra photons thereby increasing the internal temperature of *** B accounts the hike in internal temperature and initiates a feed-back reduction of its own *** suggest that moderate SAR is beneficial for rice plants to improve agronomic traits and *** presents a potential non-transgenic method for improving rice yield by CNP treatment.

关键词： agronomic trait carbon nanoparticle flowering time rice grain quality phytochrome B yield shade avoidance response temperature sensing

印度蜂蜜提取物中的酚类化合物的抗氧化活性及α淀粉酶抑制活性研究(英文)

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中国天然药物 2012年第4期10卷 255-259页

作者： Subashini Devarajan subhashree Venugopal School of Biosciences and Technology VIT UniversityVellore-632014Tamil NaduIndia

AIM:To evaluate the antioxidant and α-amylase inhibition potential of phenolic compounds in the extracts of Indian ***:Phenolic compounds were extracted from Indian honey through column *** antioxidant poten-tial of extracted phenolic compounds was measured by two different biochemical assays:ferric reducing antioxidant power(FRAP) assay and scavenging activity on 2,2-diphenyl-1-picrylhydrazyl(DPPH) ***,α-amylase inhibition assay of phenolic compounds of honey was also ***:The scavenging inhibition rate varied from 86.8% to 78.6% from the highest(6 mg·mL-1) to the lowest(1.5 mg·mL-1) concentration,whereas,reducing power assay varied from 0.89 Abs to 0.19 Abs from the highest to the lowest *** hydroxytoluene(BHT) was used as reference compound for antioxidant assays.α-amylase inhi-bition assay is reported from the phenolic honey extracts for the first *** inhibition rate for α-amylase varied from 88.8% to 30.5% from the highest(20 μg·mL-1) to the lowest concentration(4 μg·mL-1).CONCLUSION:Honey phenolic extract possessed antioxidant and α-amylase inhibition activity,thus increasing its potential therapeutic property.

关键词： Honey Phenolic compounds Antioxidant activity DPPH and FRAP α-Amylase inhibition activity

Intra-species sequence variability in 28s rRNA gene of Oesophagostomum venulosum isolated from goats of West Bengal,India.

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Asian Pacific Journal of Tropical Medicine 2010年第7期3卷 515-518页

作者： Subhasish Bandyopadhyay Asit Kumar Bera Sourav Sikdar Sumanta De subhashree Ghosh Tanmoy Rana Samiran Bandyopadhyay Premanshu Dandapat Debasis Bhattacharya Eastern Regional Station of Indian Veterinary Research Institute 37 Belgachia Road.Kolkata-37West BengalIndia National Research Centre on Yak DirangArunachal Pradesh Eastern Regional Station of Indian Veterinary Research Institute.37 Belgachia Road.Kolkata-37 West BengalIndia

Objective:To identify genotypes of Oesophagostmum venulosum(***) prevailing in West Bengal,India by comparing variation of nucleotide sequences among 28S ***: PCR amplification of partial segment of 28 S rRNA sequence and analysis of sequence amplified product by single strand conformation polymorphism(SSCP).Results:Two distinct conformers among male and female parasites were identified by PCR-SSCP *** analysis among conformers revealed the presence of five single nucleotide polymorphisms(SNP) in codon 64,66,86,125 and *** RNA prediction structure showed that out of 5 SNPs,4 occurred at interior loop of RNA which confirmed evolutionary changes among isolates prevailing in this ***:SNPs occured in different isolates of *** might influence critical changes in rRNA folding pattern which influence evolutionary changes among isolates.

关键词： 28SrRNA PCR-SSCP Oesophagostomum SNP Secondary RNA structure