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Information for Disaster Preparedness: A Social Network Approach to Rainwater Harvesting Technology Dissemination

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International Journal of Disaster Risk Science 2014年第2期5卷 95-109页

作者： subhajyoti Samaddar Makoto Murase Norio Okada Disaster Prevention Research Institute Kyoto UniversityGokashoUjiKyoto 6110011Japan Institute for Sky Water Harvesting 1201-2 FukasawaGotemba CityShizuoka Prefecture 4120023Japan Institute for the Research of Disaster Area Reconstruction Kwansei Gakuin UniversityHyogo 6628501Japan

Rainwater harvesting technology is considered an innovative and effective mechanism for reducing drinking water risks due to arsenic contamination and water salinity in coastal Bangladesh. However, adoption of such tanks remains elusive. Most studies on disaster risk communication are predominantly based on individuallevel cognitive modeling approaches, which fail to address the role of social groups, human relations, and other collective social factors in the dissemination process of disaster preventive measures. From the viewpoint of social implementation, community adoption of unfamiliar technology for disaster risk mitigation and preparedness requires another approach. Given the challenge to promote rainwater harvesting technology in the study area of coastal Bangladesh, this study examines the role of various social networks including cohesive groups(friends), structural equivalent groups(individuals who have the same position in society), and spatial groups(neighbors) in three information sharing and processing activities—hearing, observation, and discussion. Results show that those individuals who have similar cohesive affiliations tend to become hearing and discussion partners. Cohesive groups share a learning opportunity and are bounded by normative constraints in terms of direct and intimate social *** groups facilitate observation, which provides visual learning. Structurally equivalent groups are not relevant in adoption dissemination;therefore competition or similar social environment did not influence the rainwater tank dissemination activities.

关键词： disaster harvesting tank

Oligodendroglial heterogeneity in health,disease,and recovery:deeper insights into myelin dynamics

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Neural Regeneration Research 2025年第11期20卷 3179-3192页

作者： Pieter-Jan Serneels Julie D.de Schutter Lies de Groef Lieve Moons Steven Bergmans KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionNeural Circuit Development&Regeneration Research GroupLeuvenBelgium KU Leuven Leuven Brain InstituteDepartment of BiologyAnimal Physiology and Neurobiology DivisionCellular Communication&Neurodegeneration Research GroupLeuvenBelgium

decades of research asserted that the oligodendroglial lineage comprises two cell types:oligodendrocyte precursor cells and ***,recent studies employing single-cell RNA sequencing techniques have uncovered novel cell states,prompting a revision of the existing *** forward,the oligodendroglial lineage should be delineated into five distinct cell states:oligodendrocyte precursor cells,committed oligodendrocyte precursor cells,newly formed oligodendrocytes,myelin-forming oligodendrocytes,and mature *** new classification system enables a deeper understanding of the oligodendroglia in both physiological and pathological *** this uniform terminology will facilitate comparison and integration of data across ***,including the consolidation of findings from various demyelinating models,is essential to better understand the pathogenesis of demyelinating ***,comparing injury models across species with varying regenerative capacities can provide insights that may lead to new therapeutic strategies to overcome remyelination ***,by standardizing terminology and synthesizing data from diverse studies across different animal models,we can enhance our understanding of myelin pathology in central nervous system disorders such as multiple sclerosis,Alzheimer's disease,and amyotrophic lateral sclerosis,all of which involve oligodendroglial and myelin dysfunction.

关键词： animal models demyelination fish mammals multiple sclerosis myelin neurodegeneration oligodendrocytes oligodendroglial lineage remyelination

Factors Impacting Participatory Post‑Disaster Relocation and Housing Reconstruction:The Case of Tsholotsho District,Zimbabwe

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International Journal of Disaster Risk Science 2024年第1期15卷 58-72页

作者： Nombulelo Kitsepile Ngulube Hirokazu Tatano subhajyoti Samaddar department of Social Informatics Graduate School of InformaticsKyoto UniversityKyoto 606-8507Japan Disaster Prevention Research Institute(DPRI) Kyoto UniversityKyoto 611-0011Japan

Relocation is not typically considered the best planning option for post-disaster reconstruction and rehabilitation,but it may be necessary if the site has suffered severe damage or is at imminent *** is a growing recognition that strong community participation is necessary in the post-disaster relocation decision-making process since relocation can have detrimental effects on a community’s livelihood,cultural system,and way of life,among ***,the realization of this still needs to be *** of yet,few studies have examined a comprehensive account of meaningful community engagement in post-disaster relocation and reconstruction,particularly in developing *** study investigated what factors influenced local communities’ participation in post-disaster relocation and reconstruction works after the 2017Cyclone Dineo flood disaster in the Tsholotsho District of *** research methods such as face-to-face interviews,observations,and focus groups were used to collect qualitative data from a purposive sample of 25 community members and 6 *** empirical investigation showed that despite the fact that the relocation project was conceived as a community-centered project,there was no meaningful community engagement,due to the absence of a participatory framework or planning guidelines for stakeholder engagement,as well as the lack of political willingness among government *** study concluded that the lack of community involvement led to local communities abandoning the reconstruction sites because relocation projects failed to accommodate the cultural beliefs,place attachments,and livelihood concerns of local *** study suggested that it is imperative to enhance the awareness of government officials and other stakeholders about the importance of community participation for the effective implementation of post-disaster relocation *** community participation can also provide avenues fo

关键词： Community rehabilitation Housing reconstruction-Participatory relocation Zimbabwe

Community Insights:Citizen Participation in Kamaishi Unosumai decade-Long Recovery from the Great East Japan Earthquake

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International Journal of Disaster Risk Science 2023年第6期14卷 886-897页

Numerous scholars and researchers have long advocated for citizen engagement in post-disaster recovery and reconstruction initiatives,although unique opportunities and challenges in effectively implementing citizen engagement still *** has been 12 years since the Great East Japan Earthquake,where the government called for a citizen-centered recovery and reconstruction process,and reconstruction in most areas in the Tohoku region has almost been *** qualitative data acquired through interviews with the residents,field observations during the World Bosai Walk,and questionnaire and archival research,this study aimed to discuss the overall reconstruction of Unosumai in Iwate Prefecture,giving the residents'perspective on the benefits and challenges they faced in participating in recovery planning and reconstruction and how the community has been able to strengthen their participation in disaster reduction initiatives since the earthquake and *** discussion is crucial as it would effectively offer lessons on engaging residents in post-disaster recovery and reconstruction after mega-disasters.

关键词： Community participation Community perspective Japan Post-disaster Reconstruction Recovery planning

How Participatory is Participatory Flood Risk Mapping? Voices from the Flood Prone Dharavi Slum in Mumbai

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International Journal of Disaster Risk Science 2022年第2期13卷 230-248页

作者： subhajyoti Samaddar Ha Si Xinyu Jiang Junho Choi Hirokazu Tatano Disaster Prevention Research Institute Kyoto UniversityKyoto 6110011Japan School of Management Wuhan University of TechnologyWuhan 430070China Disaster and Safety Management Soongsil UniversitySeoul 06978South Korea

Participatory flood risk mapping(PFRM) is a well-recognized and widely implemented tool for meaningful community involvement in disaster risk reduction(DRR). The effectiveness of PFRM remains anecdotal. The PFRM exercise has rarely been applied identically in two different places by two different organizations, which produces varied and uncertain outcomes. In the absence of any agreed and comprehensive framework for participatory DRR, existing studies struggle to provide a scientific account of how the structure, design, and process of PFRM ensure the effective participation of local *** study, examines what factors and methods make PFRM an effective participatory DRR tool. In this study,we first identified the process-based criteria of participation. Then we briefly introduced a participatory flood risk mapping exercise conducted in a flood-prone informal settlement in Dharavi, Mumbai. The exercise was carefully designed to meet the process criteria of effective participation. Finally, using qualitative research methods, we evaluated the effectiveness of our PFRM from the local community perspective. The findings show that ensuring community livelihood security and true involvement of marginalized groups, preparing an action plan, and incorporating fun and cultural connotations into the facilitation process are critical components that enhance community participation through PFRM in DRR.

关键词： Dharavi Evaluation Mumbai flood Participatory disaster risk reduction Participatory flood risk mapping Process-based criteria of participation

Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun Zhao de-En Xu Ming-Lei Wu Ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

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World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： Xiu-Ying Chen Fa Shen Chang Cheng Yu-Han Wang Wen-Chao Cheng de-Zhi Yuan Wen Huang department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang Wen-Wei Wang Jing-Shui Zhen Bo-Cheng Li de-Cheng Cai Yang-Yang Du Hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

Inflammasome links traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1644-1664页

作者： Gabriela Seplovich Yazan Bouchi Juan Pablo de Rivero Vaccari Jennifer C.Munoz Pareja Andrew Reisner Laura Blackwell Yehia Mechref Kevin K.Wang J.Adrian Tyndall Binu Tharakan Firas Kobeissy department of Surgery Morehouse School of MedicineAtlantaGAUSA department of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA department of Neurological Surgery and the Miami Project to Cure Paralysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pediatric Critical Care Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA department of Pediatrics Emory UniversityAtlantaGAUSA department of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA department of Chemistry and Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease are three distinct neurological disorders that share common pathophysiological mechanisms involving neuroinflammation. One sequela of neuroinflammation includes the pathologic hyperphosphorylation of tau protein, an endogenous microtubule-associated protein that protects the integrity of neuronal cytoskeletons. Tau hyperphosphorylation results in protein misfolding and subsequent accumulation of tau tangles forming neurotoxic aggregates. These misfolded proteins are characteristic of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease and can lead to downstream neuroinflammatory processes, including assembly and activation of the inflammasome complex. Inflammasomes refer to a family of multimeric protein units that, upon activation, release a cascade of signaling molecules resulting in caspase-induced cell death and inflammation mediated by the release of interleukin-1β cytokine. One specific inflammasome, the NOD-like receptor protein 3, has been proposed to be a key regulator of tau phosphorylation where it has been shown that prolonged NOD-like receptor protein 3 activation acts as a causal factor in pathological tau accumulation and spreading. This review begins by describing the epidemiology and pathophysiology of traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease. Next, we highlight neuroinflammation as an overriding theme and discuss the role of the NOD-like receptor protein 3 inflammasome in the formation of tau deposits and how such tauopathic entities spread throughout the brain. We then propose a novel framework linking traumatic brain injury, chronic traumatic encephalopathy, and Alzheimer's disease as inflammasomedependent pathologies that exist along a temporal continuum. Finally, we discuss potential therapeutic targets that may intercept this pathway and ultimately minimize long-term neurological decline.

关键词： Alzheimer's disease caspase-1 chronic traumatic encephalopathy inflammasomes neurodegeneration neuroinflammation NLRP1 NLRP3 pyroptosis tauopathy traumatic brain injury