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Advances in Atmospheric Sciences 2016年第2期33卷 221-232页

作者： su jeong LEE Myoung-Hwan AHN Yeonjin LEE Department of Atmospheric Science and Engineering Ewha Women’s University

Atmospheric instability information derived from satellites plays an important role in short-term weather forecasting, especially the forecasting of severe convective storms. For the next generation of weather satellites for Korea＇s multi-purpose geostationary satellite program, a new imaging instrument has been developed. Although this imaging instrument is not de- signed to perform full sounding missions and its capability is limited, its multi-spectral infrared channels provide information on vertical sounding. To take full advantage of the observation data from the much improved spatiotemporal resolution of the imager, the feasibility of an artificial neural network approach for the derivation of the atmospheric instability is investigated. The multi-layer perceptron model with a feed-forward and back-propagation training algorithm shows quite a sensitive re- sponse to the selection of the training dataset and model architecture. Through an extensive performance test with a carefully selected training dataset of 7197 independent profiles, the model architectures are selected to be 12, 5000, and 0.3 for the number of hidden nodes, number of epochs, and learning rate, respectively. The selected model gives a mean absolute error, RMSE, and correlation coefficient of 330 J kg-1, 420 J kg-1, and 0.9, respectively. The feasibility is further demonstrated via application of the model to real observation data from a similar instrument that has comparable observation channels with the planned imager.

关键词： CAPE artificial neural network instability geostationary imager

Ethanol extract of Kalopanax septemlobus leaf inhibits HepG2 human hepatocellular carcinoma cell proliferation via inducing cell cycle arrest at G_1 phase

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 336-342页

作者： Cheol park Ji-suk jeong Jin-Woo jeong sung Ok Kim Yong-Joo Kim Gi-Young Kim su-Hyun Hong Yung Hyun Choi Department of Molecular Biology College of Natural Sciences and Human EcologyDongeui University Department of Research and Development of Resources Gurye-gun Agricultural Center Wild Flower Institute.Gurye-gun Anti-Aging Research Center.Dongeui University Department of Food Science & Biotechnology College of EngineeringKyungsung University Republic of Korea Laboratory of Immunobiology.Department of Marine Life.Sciences.Jeju National University Department of Biochemistry.Dongeui University

Objective:To investigate the effects of an ethanol extract of Kalopanax septemlobus(Thunb.)***(EEKS) on cell proliferation in human hepatocellular carcinoma cells and its mechanisms of ***:Cells were treated with EEKS and subsequently analyzed for cell proliferation and flow cytometry *** of cell cycle regulators were determined by reverse transcriptase polymerase chain reaction analysis and Western blotting,and activation of eyclin-associaled kinases studied using kinase ***:The EEKS suppressed cell proliferation in both HepG2 and Hep3 B cells,but showed a more sensitive anli-proliferative activity in HepG2 *** cytometry analysis revealed an association between the growth inhibitory effect of EEKS and with G_1 phase cell cycle arrest in HepG2 cells,along with the dephosphorylation of retinoblastoma protein(pRB) and enhanced binding of pRB with the E2 F transcription factor family *** with EEKS also increased the expression of cyclin-dependent kinase(CDK) inhibitors,such as p21WAF1/CIP1 and *** any noticeable changes in G_1 cyclins and CDKs(except for a slight decrease in CDK4).Treatment of HepG2 cells with EEKS also increased the binding of p21 and p27 with CDK4 and *** was paralleled by a marked decrease in the cyclin D- and cyclin E-associated kinase ***:Overall,our findings suggest that EEKS may be an effective treatment for liver cancer through suppression of cancer cell proliferation via G_1,cell cycle arrest Further studies arc required to identify the active compounds in EEKS.

关键词： Kalopanax septemlobus Hepatocellular carcinoma G1 cell cycle arrest CDK inhibitor pRB

MOF‑Derived CoSe2@N‑Doped Carbon Matrix Confined in Hollow Mesoporous Carbon Nanospheres as High‑Performance Anodes for Potassium‑Ion Batteries

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Nano-Micro Letters 2021年第1期13卷 123-137页

作者： su Hyun Yang Seung‑Keun park Yun Chan Kang Department of Materials Science and Engineering Korea UniversityAnam‑DongSeongbuk‑GuSeoul 136‑713Republic of Korea Department of Chemical Engineering Kongju National University1223‑24 Cheonan‑daeroSeobuk‑guCheonan 31080Republic of Korea

In this work,a novel vacuum-assisted strategy is proposed to homogenously form Metal-organic frameworks within hollow mesoporous carbon nanospheres(HMCSs)via a solid-state *** method is applied to synthesize an ultrafine CoSe2 nanocrystal@N-doped carbon matrix confined within HMCSs(denoted as CoSe2@NC/HMCS)for use as advanced anodes in highperformance potassium-ion batteries(KIBs).The approach involves a solvent-free thermal treatment to form a Co-based zeolitic imidazolate framework(ZIF-67)within the HMCS templates under vacuum conditions and the subsequent *** treatment under vacuum facilitates the infiltration of the cobalt precursor and organic linker into the HMCS and simultaneously transforms them into stable ZIF-67 particles without any *** the subsequent selenization process,the“dual confinement system”,composed of both the N-doped carbon matrix derived from the organic linker and the small-sized pores of HMCS,can effectively suppress the overgrowth of CoSe2 ***,the resulting uniquely structured composite exhibits a stable cycling performance(442 mAh g^−1 at 0.1 A g^−1 after 120 cycles)and excellent rate capability(263 mAh g^−1 at 2.0 A g^−1)as the anode material for KIBs.

关键词： Metal-organic frameworks Hollow mesoporous carbon nanospheres Potassium-ion batteries Cobalt selenides Electrode materials

What is the best strategy for successful bowel preparation under special conditions?

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World Journal of Gastroenterology 2014年第11期20卷 2741-2745页

作者： Yun jeong Lim su Jin Hong Department of Internal Medicine College of MedicineDongguk UniversityGyeonggi-Do 410-773South Korea Digestive Disease Center and Research Institute Department of Internal MedicineSoonchunhyang University College of MedicineBucheonGyeonggi-Do 420-767South Korea

Adequate bowel preparation is important for successful colonoscopic examination. Several effective colonic cleansing agents are available and routinely prescribed, but each carries its own limitations and benefits from particular dosing regimens. The most frequently prescribed colonic cleansing agent, the polyethylene glycol (PEG) cathartic solution, suffers from low patient compliance in general, due to its unpalatable taste and smell coupled with the large ingested volumes required. However, PEG is preferred over other cathartics for use in individuals of advanced age, sufferers of chronic kidney disease, heart failure and inflammatory bowel disease, and women who are pregnant or lactating. The laxative agents sodium phosphate (NaP) and sodium picosulfate plus magnesium citrate have been applied and have improved patient compliance and tolerance. NaP, however, should be avoided in individuals with impaired renal function or plasma clearance, such as those with chronic kidney disease, who are taking drugs that affect renal function, or who suffer from heart failure. Other special conditions that may affect an individual’s tolerance of the cathartic agent or ability to complete the administration routine include stroke, severe constipation, hematochezia, suspicious lower gastrointestinal bleeding, and mental disorders such as dementia. All ingestible bowel preparation solutions can be instilled into the stomach and duodenum through nasogastric tube or esophagogastroduodenoscope with the aid of a water irrigation pump for patients with difficulties swallowing or ingesting the large volumes of fluid required. In addition, dietary regimens based on clear liquids and low-residue foods for 1-4 d prior to the colonoscopy may be supplemental bowel preparation strategies. Achieving an effective and safe cleansing of the bowel is important for successful colonoscopy in all patients, so full knowledge of the individual’s condition and capabilities is necessary

关键词： Colonoscopy Preparation Polyethylene glycols Special conditions Cathartic agent

successful treatment of relapsed acute promyelocytic leukemia with arsenic trioxide in a hemodialysis-dependent patient: A case report

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World Journal of Clinical Cases 2020年第21期8卷 5347-5352页

作者： Hee jeong Lee Sang-Gon park Department of Hemato-Oncology Chosun University HospitalGwang-ju 501-717South Korea Department of Internal Medicine Hemato-oncologyChosun University HospitalGwangju 61453South Korea

BACKGROUND Arsenic trioxide(ATO)is recommended for patients who do not achieve molecular remission or who have molecular or morphologic ***,there are no guidelines for adjusting ATO dosage in patients with severe renal failure or on ***,we report the successful treatment of relapsed acute promyelocytic leukemia(APL)in a patient on hemodialysis with ATO single agent and review the cases in *** suMMARY A 46-year-old woman who has been on hemodialysis to chronic glomerulonephritis for 15 years visited our hospital for *** had been seen for pancytopenia 3 years ago and had been diagnosed with *** also received chemotherapy for APL but unfortunately was lost to follow-up after her second consolidation *** was noted to have pancytopenia by her nephrologist during hemodialysis 1 mo *** marrow biopsy and reverse transcriptase-polymerase chain reaction(RT-PCR)tests revealed a diagnosis of relapsed *** for relapsed APL with ATO single agent was started and she achieved molecular remission after administering 24 doses of *** far,four consolidation therapies have been performed with the ATO single agent,and,to date,the molecular remission has been maintained as negative promyelocytic leukemia/retinoic acid receptor-αfusion gene as confirmed by RTPCR testing for two *** This is a rare case of relapsed APL successfully treated with the single agent ATO in a patient on hemodialysis.

关键词： Arsenic trioxide Acute promyelocytic leukemia Pancytopenia Hemodialysis Promyelocytic leukemia/retinoic acid receptor-αfusion gene Case report

Helicobacter pylori infection in gastric mucosa-associated lymphoid tissue lymphoma

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World Journal of Gastroenterology 2014年第11期20卷 2751-2759页

作者： jeong Bae park Ja Seol Koojeong Department of Internal Medicine College of MedicineDongguk UniversityGyeongju 780-350South Korea Division of Gastroenterology and Hepatology Department of Internal MedicineKorea University Ansan HospitalAnsan 425-707South Korea

Gastrointestinal lymphoma is the most common type of extranodal lymphoma,and most commonly affects the *** zone B-cell lymphoma of the mucosa-associated lymphoid tissue(MALT)and diffuse large B-cell lymphoma are the most common histologic types of gastric *** its increasing incidence,diagnosis of gastric lymphoma is difficult at an earlier stage due to its nonspecific symptoms and endoscopic findings,and,thus,a high index of suspicion,and multiple,deep,repeated biopsies at abnormally and normally appearing sites in the stomach are *** addition,testing for Helicobacter pylori(***)infection and endoscopic ultrasonography to determine the depth of tumor invasion and involvement of regional lymph nodes is essential for predicting response to *** eradication and for assessment of disease *** addition,*** infection and MALT lymphoma development are associated,and complete regression of low-grade MALT lymphomas after *** eradication has been *** and/or chemotherapy can be used in cases that show poor response to *** eradication,negativity for *** infection,or high-grade lymphoma.

关键词： Mucosa-associated lymphoid tissue Lymphoma Helicobacter pylori Eradication Remission

Effects of PWHT on Microstructure and Mechanical Properties of Weld Metals of Ni-Based superalloy 617 and 263 for Hyper-supercritical Power Plants

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Acta Metallurgica Sinica(English Letters) 2016年第12期29卷 1107-1118页

作者： jeong Kil Kim Hae Ji park Deog Nam Shim Doosan Heavy Industries and Construction ChangwonGeongnam Korea

It is well known that solid solution-strengthened alloy 617 and γ′ precipitation-strengthened alloy 263 have excellent mechanical properties and corrosion resistance at high temperatures. Hyper-supercritical power plants work at temperatures above 700 ℃, and these superalloys are considered candidate materials for steam turbines components of these power plants. In this study, gas tungsten arc weldability of these superalloys was evaluated, and the effects of post- weld heat treatment （PWHT） on the microstructural characteristics and the mechanical properties of their weld metals were investigated. Scanning transmission electron microscopy, energy-dispersive spectroscopy and electron probe microanalysis were utilized for the investigation. The experimental results confirmed that these weld metals had different characteristics in microstructure and mechanical properties. PWHT resulted in the precipitation of intergranular carbides, γ′ particles and an increase in tensile strength of these superalloy weld metals. Furthermore, fine γ′ particles, which were not detected in the as-welded metal of alloy 263, were precipitated after PWHT and those particles were the reason for the drastic increase in tensile strength.

关键词： superalloy Welding Precipitation Segregation

Rapidly growing primary anal canal lymphoma:a case report and literature review

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Gastroenterology Report 2023年第1期11卷 582-584页

作者： Yu Kyung Chung su Bum park Department of Internal Medicine Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsanRepublic of Korea

Introduction Anal cancer is a rare cancer accounting for2%of all gastrointestinal tract malignancies[1].Among anal cancers,squamous cell cancer(SCC)is the most common and lymphoma is one of the least *** gastrointestinal tract is the most common site for extranodal non-Hodgkin’s lymphoma(NHL),and diffuse large B-cell lymphoma(DLBCL)is the most common histologic ***,primary colorectal lymphoma accounts for only 0.3%of all large intestinal malignancies and3%of all gastrointestinal lymphomas[2].Anal canal SCC and lymphomas are treated differently;thus,accurate diagnosis is crucial.

关键词： lymphoma gastrointestinal diagnosis

Efficient and secure source authentication scheme for multicast user authentication

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Journal of Central South University 2013年第10期20卷 2741-2746页

作者： jeong Yoon-su LEE Sang-hyuk SHIN Seung-soo Department of Information Communication Engineering Mokwon University Department of Electrical and Electronic Engineering Xi’an Jiaotong-Liverpool University Department of Information Security Tongmyong University

Multicast technology application has been widely utilized in broadband internet. Source authentication is one of the most needs for many multicast applications transferring real-time information such as stream video and online news. Because multicast current services provided to the group members are changed dynamically, data transferring by a group member is not used by the recipient. In order to verify the identity of the sender who sent the packet and to make sure that the data have not been tampered, an optimized source authentication scheme has been proposed to transfer the authentication information not to the next-door packet. The proposed method for multiple packets authenticates the source with a limited number of electronic signatures. The proposed method can reduce overhead compared to the method by adding a digital signature for every packet. In addition, by sending the generated electronic signature to the first packet and the last packet, it prevents the loss of consecutive packets, as well as a source authentication can be provided in real-time services.

关键词： multicast packet source authentication broadband Internet

Diagnosing isolated superior mesenteric artery dissection and thrombosis using point-of-care ultrasonography:A case series

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World Journal of Emergency Medicine 2022年第3期13卷 239-241页

作者： Sin Youl park Won Joon jeong Department of Emergency Medicine Yeungnam University Medical CenterDaegu 42415Republic of Korea Department of Emergency Medicine Chungnam National University HospitalDaejeon 301721Republic of Korea

Dear editor,Most superior mesenteric artery (SMA) dissections occuralongwithaorticdissections;isolatedSMA dissectionsarerare(incidencerateof0.06%).[1] A diagnosis of SMA dissection is generally made using contrast-enhancedcomputedtomography(CECT);however, bedside point-of-care ultrasound (POCUS)may hasten the process. Herein, we present a case series of isolated SMA dissections that were suspected and confirmed using POCUS and CECT, respectively.

关键词： point process editor