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Pharmacological effects of volatile oil from chrysanthemum and its associated mechanisms:a review

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Acupuncture and Herbal Medicine 2024年第1期4卷 79-91页

作者： Jing Zhang Weiqiang su Nina Filipczak Ying luo Anping Wan Yao He Shijuan Yan Xiang Li Ming Yang Key Laboratory of Modern Preparation of TCM Ministry of EducationJiangxi University of Chinese MedicineNanchangChina Center for Pharmaceutical Biotechnology and Nanomedicine Northeastern UniversityBostonUSA National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine Jiangxi University of Chinese MedicineJiangxi University of Chinese MedicineNanchangChina

Volatile oil(VO)is the main chemical component of common plants in Chrysanthemum genus,and it possesses several beneficial pharmacological properties,including bacteriostatic,antioxidant,anti-tumor,anti-inflammatory,antipyretic,analgesic,antiosteoporotic,antihypertensive,sedative,and hypnotic *** date,research on the effective components of Chrysanthemum extract has mainly focused on flavonoids,whereas limited data are available on the chemical constituents and underlying mechanisms of action of the VO *** this review,the pharmacological activities and mechanisms of VO are comprehensively reviewed with the aim of providing a foundation for further development for medicinal,aromatherapy,and diet therapy applications.

关键词： Action mechanisms Chrysanthemum Pharmacological activity Volatile oil

Long-term tadalafil once daily in Chinese men with erectile dysfunction:a 2-year final analysis of a post-marketing,multicenter,randomized,open-label trial

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Asian Journal of Andrology 2024年第3期26卷 282-287页

作者： Hui Jiang Lian-Ming Zhao su Yan Ji-Hong Liu Zhao-Hui Zhu Jin-Dan luo Yu-Tian Dai Fu-Biao Li Hao-Cheng Lin Zhi-Chao Zhang Department of Urology Peking University First HospitalBeijing 100000China Department of Urology Peking University Third HospitalBeijing 100191China Department of Urology Peking Union Medical College HospitalBeijing 100730China Department of Urology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Urology Union Hospital of Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Urology The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Departmentof Andrology Nanjing Drum Tower HospitalNanjing 210008China Department of Andrology The First Hospital of Jilin UniversityChangchun 130021China Andrology Center Department of UrologyPeking University First HospitalBeijing 100034China

The long-term safety and effectiveness of once-daily tadalafil is crucial,but limited data are available in Chinese patients witherectile dysfunction(ED).In this post-marketing,multicenter,randomized,open-label trial with 2-year follow-up,635 ED caseswere randomized to receive daily oral tadalafil 2.5 mg or 5 mg for 3 months,of whom 580 continued once-daily tadalafil 5 mg for21 ***-emergent adverse events in the 12-month and 24-month period were similar,with the most common beingviral upper respiratory tract infection,upper respiratory tract infection,and *** improvement from baseline inthe International Index of Erectile Function-Erectile Function(IIEF-EF)score was detected at month 12(least squares mean[LSM]change:7.9,95%confidence interval[CI]:7.5–8.4,Psults showed improved erection function in 97.5%ofpatients and improved ability to engage in sexual activity in 95.9%of patients at month 12;these values were 96.1%and 95.0%at month 24,*** quality of sexual life score based on the Sexual Life Quality Questionnaire(SLQQ)was increased by52.2%at month 12 and by 55.3%at month 24(both Psus 65.9±20.2 at month ***-year daily application of tadalafil 5mg in Chinese men with ED showed a favorable safety profile and durable improvement in sexual performance and satisfaction.

关键词： clinical trial erectile dysfunction long-term safety once-daily dosing tadalafil

Incidence and mortality of liver cancer in Henan province in 2015

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Chronic Diseases and Translational Medicine 2019年第3期5卷 197-202页

作者： Xiao-Qin Cao Ru-Fei Cao Shu-Zheng Liu Qiong Chen Pei-Liang Quan su-Xia luo Henan Cancer Prevention and Control Office Affiliated Tumor Hospital of Zheng zhou University/Henan Cancer HospitalZheng zhouHenan 450008China College of Medical Laboratory Zunyi Medical UniversityZunyiGuizhou 563000China

Objective:Liver cancer is one of the most common types of *** aimed to use the cancer registration data in 2015 to estimate the incidence and mortality of liver cancer in Henan ***:The data from 37 population-based cancer registries in Henan province were collected for this *** pooled data were stratified by area,sex,and age *** cases of liver cancer and deaths due to the disease were estimated using age-specific rates and provincial population in *** incidence and death rates were age standardized to the 2000 Chinese standard population and Segi's population,which were expressed per 100,000 ***:After clearance and assessment,data from 30 population-based cancer registries(5 in urban and 25 in rural areas)were included in the *** 30 cancer registries encompassed a total population of 23,421,609(3,507,984 in urban and 19,913,625 in rural areas),accounting for 21.84% of the provincial *** proportion of morphological verification(MV%),percentage of cancer cases identified with death certification only(DCO%),and mortality-to-incidence ratio(M/I)were 38.55%,2.34%,and 0.81,*** 31,639 new cases of liver cancer were diagnosed and 26,057 deaths from liver cancer occurred in Henan in *** crude incidence rate of liver cancer was 27.05/100,000(36.24/100,000 in men and 17.35/100,000 in women).Age-standardized incidence rates by Chinese standard population and world standard population were 21.10/100,000 and 20.95/100,000,*** cancer was more common in men than in *** incidence rates in urban(26.31/100,000)and rural(27.18/100,000)areas were *** crude mortality rate of liver cancer was 21.98/100,000(29.33/100,000 in males and 14.22/100,000 in females).Age-standardized mortality rates by Chinese standard population and world standard population were 16.93/100,000 and 16.90/100,000,*** was no distinct difference in mortality rates of liver ca

关键词： Liver cancer Cancer registry Incidence Mortality Henan province

二次受力下自密实混凝土加固RC梁受弯性能研究

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工程力学 2015年第4期32卷 62-68页

作者：罗素蓉吴文达陈彪福州大学土木工程学院福建福州350108

为模拟实际工程中加固构件的真实承载能力,实验在原混凝土构件持续受荷状态下,采用自密实混凝土对构件进行加固、养护。共进行了7根二次受力下自密实混凝土加固钢筋混凝土梁和2根对比梁的受弯性能试验,研究了不同初始受力水平、不同加... 详细信息

为模拟实际工程中加固构件的真实承载能力,实验在原混凝土构件持续受荷状态下,采用自密实混凝土对构件进行加固、养护。共进行了7根二次受力下自密实混凝土加固钢筋混凝土梁和2根对比梁的受弯性能试验,研究了不同初始受力水平、不同加固厚度及不同界面处理方式对加固钢筋混凝土梁抗弯承载力和截面刚度的影响。试验量测了构件裂缝分布形态、荷载-挠度曲线、钢筋应变发展规律等。结果表明:采用自密实混凝土加固钢筋混凝土梁,能有效地提高钢筋混凝土梁的抗弯承载力、截面刚度等性能;二次受力下自密实混凝土加固梁抗弯承载力随着初始受力水平的增大而降低。在试验结果的基础上,基于平截面假定,提出了二次受力下自密实混凝土加固梁钢筋滞后应变及抗弯承载力计算式,计算结果与试验结果吻合良好。

关键词：自密实混凝土增大截面法加固二次受力简支梁受弯性能

农业环境核算实地研究——以浙江加华种猪有限公司为例

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安徽农业科学 2011年第21期39卷 13232-13234,13239页

作者：罗素清浙江师范大学财务会计教育系浙江金华321004

以浙江加华种猪有限公司为例,根据从农业公司调查的有关资料和数据,采用货币计量、物理单位或文字说明对环境工程项目、节电、节水、排污费、非产品产出等进行农业环境核算,从而对我国未来农业企业的环境核算进行探索性研究。

关键词：农业环境核算货币计量效益分析

三峡库区后移民时代发展的路径选择和财政政策

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安徽农业科学 2011年第18期39卷 11275-11277页

作者：罗素娟南昌大学科学技术学院江西南昌330029

首先,阐述了三峡库区后移民时代发展现状:一是生态库区的定位与发展存在矛盾;二是采取市场选择、政府引导的开发性移民模式;三是移民后期扶持任务艰巨;四是地质灾害的防治与环境治理。其次,概括和梳理得到三峡库区后移民时代发展可采取... 详细信息

首先,阐述了三峡库区后移民时代发展现状:一是生态库区的定位与发展存在矛盾;二是采取市场选择、政府引导的开发性移民模式;三是移民后期扶持任务艰巨;四是地质灾害的防治与环境治理。其次,概括和梳理得到三峡库区后移民时代发展可采取的路径:一是扶持移民安稳致富;二是支持库区产业发展;三是加强库区生态环境建设;四是加大中央财政政策的支持。最后,从财政政策视角提出了三峡库区后移民时代发展的政策建议:一是促进生态移民搬迁及移民安稳致富的财税政策措施,具体包括促进移民就业的财税政策措施、为移民提供社会保障的财税政策措施、财政补贴和税收优惠、追加后续投资解决迁建遗留的问题四大措施;二是促进库区产业发展的财税政策措施,具体包括发挥产业基金的产业造血功能与优化库区产业结构、给予特殊的税收优惠政策与引导资金投向三峡库区、增强地方财力的财税政策措施三大措施。

关键词：三峡库区后移民时代发展路径财政政策

How to Teach English Reading in Senior High School

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青年文学家 2009年第24期 73-74页

作者：罗爱华黄山学院安徽省宿松中学

English reading teaching in high school has aroused hot discussions among English teachings and educators around the country. Many teaching methods have been proposed and discussed. This paper intends to present three teaching methods of high school English reading course - newspapers as teaching materials,good reading habits and techniques,and task-based teaching method.

关键词： English reading teaching senior high school

Effects of Curcumin on Neuroinflammation and the Nrf2/HO-1 Pathway in Rat Brains Following Gas Explosion

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Biomedical and Environmental Sciences 2024年第8期37卷 943-947页

作者： Xinwen Dong Yaguang su Zheng luo Lyufei Deng Xiaofeng Han Yifang Liang Sanqiao Yao Weidong Wu Jia Cao Linqiang Tian Yichun Bai Wenjie Ren Health School of Public Health Xinxiang Medical UniversityXinxiang 453003HenanChina Toxicology Research Institute PLA Army Medical UniversityChongqing 400038China Institute of Trauma and Orthopaedics Xinxiang Medical UniversityXinxiang 453003HenanChina Institutes of Health Central Plains Xinxiang Medical UniversityXinxiang 453003HenanChina

Gas explosions,a major occupational hazard in China’s coal industry,endanger the lives and health of *** explosions cause a specific type of traumatic brain injury with complex mechanisms,leading to disability and death.A study by Zhao et *** magnetic resonance imaging on 49 gas explosion survivors revealed significant damage to brain regions like the hippocampus and cerebral cortex.

关键词： damage Nrf2 cerebral

suppressive effect of Armoracia rusticana and three main glucosinolates on heterocyclic amine generation in roasted fish patties and their potential mechanism analyzed by density functional theory

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Food Science and Human Wellness 2024年

作者： Zhuoming Huang Tiantian Huang Hang su Zihao Yang Jie luo Qingwu Shen Chaoyi Xue Wei Quan College of Food Science and Technology， Hunan Agricultural University State Key Laboratory of Food Science and Resources， Jiangnan University

This study investigated the suppressive effects of Armoracia rusticana (AR) and its three main glucosinolates on both free and bound heterocyclic amines (HAs)， along with their mechanisms of free radical quenching using density functional theory. Fish patties were supplemented with varying concentrations of AR (0.5%～1.5%) and glucosinolates (0.005%～0.015%)， showing a dose-dependent inhibition of HAs and concurrent elimination of free radicals and HAs intermediates. Glucobrassicin demonstrated the highest reactivity， which was verified by frontier orbit analysis and conceptual density functional parameters， consistent with experimental findings. Furthermore， the O-H bond connected to the sulfur atom of glucobrassicin possessed the smallest bond dissociation enthalpy (BDE) value， which indicated that this particular hydrogen atom is most susceptible to react with free radicals. Overall， AR and its glucosinolates， especially glucobrassicin， show promise as natural additives for improving food safety and quality.

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