检索结果-南通市图书馆

2023年美国麻醉医师学会神经肌肉阻滞监测与拮抗实践指南:美国麻醉医师学会工作组关于神经肌肉阻滞的报告

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中华麻醉学杂志 2024年第5期44卷 518-542页

作者： Stephan R.Thilen Wade A.Weigel Michael M.Todd Richard P.Dutton Cynthia A.Lien stuart A.Grant Joseph W.Szokol Lars I.Eriksson Myron Yaster Mark D.Grant Madhulika Agarkar Anne M.Marbella Jaime F.Blanck Karen B.Domino 西雅图华盛顿州明尼阿波里斯明尼苏达州达拉斯得克萨斯州密尔沃基威斯康星州教堂山北卡罗来纳州洛杉矶加利福尼亚州斯德哥尔摩瑞典丹佛科罗拉多州绍姆堡伊利诺斯州巴尔的摩马里兰州

本实践指南基于证据提供了全身麻醉期间及术后神经肌肉功能监测与阻滞拮抗的管理推荐。主要关注神经肌肉功能监测的类型与部位及阻滞拮抗的过程,以减少肌肉松弛药残留阻滞。

关键词：神经肌肉阻滞肌肉松弛药神经肌肉功能监测舒更葡糖钠新斯的明

Probable effects of heat advection on the adjacent environment during oil production at Prudhoe Bay, Alaska

在线全文

学校读者我要写书评

暂无评论

Research in Cold and Arid Regions 2016年第6期8卷 451-460页

作者： stuart A.Harris Department of Geography University of Calgary Calgary Alberta T2N 1N4 Canada

The latest available data for mean annual air temperature at sites away from the Arctic coast in both Alaska and the Yukon Territory show no significant warming in the last 30-50 years. However, around the Arctic coast of northwest North America centered on Prudhoe Bay, the weather stations show significant warming of both the air and the ocean water, resulting in substantial losses in sea ice west of Prudhoe Bay. These changes appeared shortly after the commencement of shipment of oil through the Trans-Alaska Pipeline in 1977, but have now reached a quasi-stable thermal state. Since more than 17 trillion barrels of oil have passed through the pipeline after being cooled by the adjacent air, which in turn, can then result in the melting of the adjacent sea ice, there appears to be a very strong relationship between these events, and a marked lack of correlation with the changes of the content of greenhouse gases in the atmosphere. This contrasts with the IPCC interpretation of the available climatic data, which assumes that the maximum climatic warming at Prudhoe Bay is typical of the entire region and is the result of increasing greenhouse gases. Engineers need to consider heat advection by oil or gas from underground when designing pipeline facilities, and to take account of the potential environmental con-sequences that they may cause.

关键词： Prudhoe Bay mean annual air temperature heat advection due to oil Arctic ice cover Trans-Alaska Pipeline greenhouse gases Arctic marine ecosystems

Recent advances in phosphoric acid-based membranes for high-temperature proton exchange membrane fuel cells

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2021年第12期30卷 393-429,I0010页

作者： Zunmin Guo Maria Perez-Page Jianuo Chen Zhaoqi Ji stuart M.Holmes Department of Chemical Engineering and Analytical Science The University of Manchester.Ml39PLUnited Kingdom

High-temperature proton exchange membrane fuel cells(HT-PEMFCs)are pursued worldwide as efficient energy conversion *** efforts have been made in the area of designing and developing phosphoric acid(PA)-based proton exchange membrane(PEM)of *** review focuses on recent advances in the limitations of acid-based PEM(acid leaching,oxidative degradation,and mechanical degradation)and the approaches mitigating the membrane *** multilayer or polymers with continuous network,adding hygroscopic inorganic materials,and introducing PA doping sites or covalent interactions with PA can effectively reduce acid *** oxidative degradation can be alleviated by synthesizing crosslinked or branched polymers,and introducing antioxidative groups or highly oxidative stable *** to get a compact structure,blending with stable polymers and inorganic materials,preparing polymer with high molecular weight,and fabricating the polymer with PA doping sites away from backbones,are recommended to improve the membrane mechanical ***,by comparing the running hours and decay rate,three current approaches,*** via thermally curing or polymeric crosslinker,*** hygroscopic inorganic materials,*** membrane layers or introducing strong basic groups and electron-withdrawing groups,have been concluded to be promising approaches to improve the durability of *** overall aim of this review is to explore the existing degradation challenges and opportunities to serve as a solid basis for the deployment in the fuel cell market.

关键词： High-temperature proton exchange membrane fuel cells Acid leaching Oxidative degradation Mechanical degradation Durability

Identification,characteristics and classification of cryogenic block streams

在线全文

学校读者我要写书评

暂无评论

Research in Cold and Arid Regions 2016年第3期8卷 177-186页

作者： stuart A.Harris Department of Geography University of CalgaryCanada T2N 1N4

Cryogenic block streams consist of a stream of rocks superficially resembling a stream deposit but lacking a matrix, usually occurring on a valley or gully floor or on slopes that are less steep than the maximum angle of repose of coarse sediments. They are usually formed on perennially frozen ground, but can also occur as relict landforms. There are three main active kinds forming today, viz., Siberian and Tibetan dynamic rock streams and lag block streams. During their formation, the blocks in the active Siberian and Tibetan dynamic block streams move downslope at up to 1 rn/a. They are forming today on the Tibetan Plateau and in the more arid parts of south-central Siberia, although the processes involved in the movement are different. In the case of the Tibetan type, individual blocks slide downslope over the substrate in winter on an icy coating in areas of minimal winter precipitation. The Siberian type develops in areas of 15-80 cm of winter snow cover and an MAAT （mean annual air temperature） of-4 ~C to -17 ~C. The movement is due to creep of snow and ice and collapse of the blocks downslope during thawing. Lag block streams are formed by meltwater flowing over the surface of sediment consisting primarily of larger blocks with a limited amount of interstitial sediment. The erosion of the matrix is primarily in the spring in areas of higher winter precipitation on 10^-30~ slopes. The blocks remain stationary, but the interstitial sediment is washed out by strong seasonal flows of meltwater or rain to form an alluvial fan. The boulders undergo weathering and become more rounded in the process. Lag block streams can also develop without the presence of permafrost in areas with cold climates or glaciers. Block streams also occur as relict deposits in older deposits under various climatic regimes that are unsuitable for their formation today. An example of relict lag block streams with subangular to subrounded blocks occurs in gullies on the forested mountainside

关键词： active dynamic block streams felsemeer relict block steams Tibetan type block streams Siberian typeblock streams lag block streams

Climatic change: Causal correlations over the last 240 Ma

在线全文

学校读者我要写书评

暂无评论

Research in Cold and Arid Regions 2013年第3期5卷 259-274页

作者： stuart A. Harris Department of Geography University of Calgary

The climate of the Earth has been oscillating between mega warm periods and mega cold periods for 3,000 Ma. Each mega cold period included alternating major warm and cold events. The present mega cold period commenced about 44 Ma in the polar re- gions as the seas cooled following the loss of the circum-equatorial ocean. Before then, a mega warm period lasted for more than 200 Ma. The frequency of the major cold events within the present mega cold period is increasing, with each continent being un- der the influence of a different set of climatic controls. There are many causes of these shifts in climate, ranging from fluctuating meridional ocean currents, rearrangement of tectonic plates, and changes in ocean gateways. These are enhanced by a combination of Milankovitch cycles and many other medium to small oscillations and cyclic controls that cause the daily, monthly, and season- al fluctuations in weather. Examples are given of how these can cause a change from cold to warm events, or vice versa, at pre- sent-day or mega scales, aided by eustatic changes in sea levels and changes in the distribution of air masses, sea ice, and snow.

关键词： climatic change main causes of glaciations and permafrost events main causes of interglacials climatic effects of plate tectonics effects of changing land and sea areas mega cold and mega warm events

Laboratory studies on leaching of HBCDD from building insulation foams

在线全文

学校读者我要写书评

暂无评论

Emerging Contaminants 2019年第1期5卷 36-44页

作者： William A.Stubbings stuart Harrad School of Geography Earth&Environmental SciencesUniversity of BirminghamBirminghamB152TTUK

A series of laboratory experiments were conducted to study emissions of hexabromocyclododecane(HBCDD)into aqueous leaching fluid under simulated landfill ***(EPS)and extruded(XPS)polystyrene building insulation foam samples containing HBCDD were contacted with deionised Milli-Q water containing 0,100 and 1000 mg L1 dissolved humic matter(DHM)as leaching *** of HBCDD were determined in the resulting fluid and single and serial batch experiments *** impacts on HBCDD concentrations in the leaching fluid temperature and pH were *** from these experiments show that HBCDD concentrations in leaching fluid following contact with EPS and XPS almost all exceeded the aqueous solubilities for each diastereomer and the technical HBCDD *** indicates that agitation and abrasion of EPS and XPS were significant mechanisms of HBCDD emission to leaching ***,under such conditions,HBCDD is likely associated with fine abraded particles of the foam and concentrations in the leaching fluid are therefore not limited by the aqueous solubility of *** with this,the length of contact time had a significant positive effect on concentrations of all diastereomers in the leaching fluid for XPS and for the least soluble diastereomer,g-HBCDD for ***,the presence of DHM in the leaching fluid and elevated leaching fluid temperatures had significant positive effects on HBCDD concentrations in leaching fluid for both EPS and ***,while leaching fluids of pH 8.5 significantly enhanced concentrations of a-HBCDD released from EPS,pH exerts a minor effect on concentrations of HBCDD in leaching fluid.

关键词： Expanded polystyrene Extruded polystyrene Hexabromocyclododecane Landfill Brominated flame retardants

Are yarn quality prediction tools useful in the breeding of high yielding and better fibre quality cotton(Gossypium hirsutum L.)?

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cotton Research 2023年第4期6卷 227-239页

作者： LIU Shiming GORDON stuart STILLER Warwick CSIRO Agriculture and Food NarrabriNSW 2390Australia CSIRO Agriculture and Food WerribeeVIC 3030Australia

Results The population had large variations for lint yield,fibre properties,predicted yarn properties,and composite fibre quality *** yield with all fibre quality traits was not *** the selection was conducted first to keep those with improved fibre quality,and followed for high yields,a large proportion in the resultant populations was the same between selections based on Cottonspec predicted yarn quality and HVI-measured fibre *** both exceeded the selection based on FQI and Background The approach of directly testing yarn quality to define fibre quality breeding objectives and progress the selection is attractive but difficult when considering the need for time and *** question remains whether yarn prediction tools from textile research can serve as an *** this study,using a dataset from three seasons of field testing recombinant inbred line population,Cottonspec,a software developed by the Commonwealth Scientific and Industrial Research Organisation(CSIRO)for predicting ring spun yarn quality from fibre properties measured by High Volume Instrument(HVI),was used to select improved fibre quality and lint yield in the *** population was derived from an advanced generation inter-crossing of four CSIRO conventional commercial *** Cottonspec program was able to provide an integrated index of the fibre qualities affecting yarn *** was compared with selection based on HVI-measured fibre properties,and two composite fibre quality variables,namely,fibre quality index(FQI),and premium and discount(PD)*** latter represents the net points of fibre length,strength,and micronaire based on the Premiums and Discounts Schedule used in the market while modified by the inclusion of *** *** The population contained elite segregants with improved yield and fibre properties,and Cottonspec predicted yarn quality is useful to effectively capture these *** is a nee

关键词： Yield Fibre properties Fibre quality index Predictive yarn quality Cotton marketing Cotton breeding

A SteMNess perspective of survival motor neuron function： splicing factors in stem cell biology and disease

在线全文

学校读者我要写书评

暂无评论

Frontiers in Biology 2015年第4期10卷 297-309页

作者： stuart J. Grice Ji-Long Liu MRC Functional Genomics Unit Department of Physiology Anatomy and Genetics University of Oxford South Parks RoadOxford OX1 3PT UK

Genome-wide analyses of metazoan messenger RNA （mRNA） species are unveiling the extensive transcriptional diversity generated by alternative splicing （AS）. Research is also beginning to identify the splicing factors and AS events required to maintain the balance between stem cell renewal （i.e stemness properties） and differentiation. One set of proteins at the center of spliceosome biogenesis are the survival motor neuron （SMN） complex constituents, which have a critical role in the assembly of spliceosomal small nuclear ribonucleoproteins （snRNPs） in all cells. In this review we discuss what is currently known about how AS controls pluripotency and cell fate and consider how an increased requirement for splicing factors, including SMN, helps to maintain an enrichment of stem cell-specific AS events. Furthermore, we highlight studies showing that mutations in specific splicing factors can lead to the aberrant development, and cause targeted degeneration of the nervous system. Using SMN as an example, we discuss the perspective of how stem cell-specific changes in splicing factors can lead to developmental defects and the selective degeneration of particular tissues. Finally we consider the expanding role of SMN, and other splicing factors, in the regulation of gene expression in stem cell biology, thereby providing insight into a number of debilitating diseases.

关键词： stem cells splicing survival motor neuron (SMN) spinal muscular atrophy (SMA)

Ron receptor-dependent gene regulation of Kupffer cells during endotoxemia

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2014年第3期13卷 281-292页

作者： Rishikesh M Kulkarni William D stuart Susan E Waltz Department of Cancer Biology University of Cincinnati Department of Research Cincinnati Veterans Affairs Medical Center

BACKGROUND: Ron receptor tyrosine kinase signaling in macrophages, including Kupffer cells and alveolar macrophages,suppresses endotoxin-induced proinflammatory cytokine/chemokine production. Further, we have also identified genes from Ron replete and Ron deplete livers that were differentially expressed during the progression of liver inflammation associated with acute liver failure in mice by microarray *** important genes and signaling pathways have been identified downstream of Ron signaling during progression of inflammation by this approach, the precise role that Ron receptor plays in regulating the transcriptional landscape in macrophages, and particular in isolated Kupffer cells, has still not been ***: Kupffer cells were isolated from wild-type(TK+/+)and Ron tyrosine kinase deficient(TK-/-) mice. Ex vivo, the cells were treated with lipopolysaccharide(LPS) in the presence or absence of the Ron ligand, hepatocyte growth factor-like protein(HGFL). Microarray and qRT-PCR analyses were utilized to identify alterations in gene expression between ***: Microarray analyses identified genes expressed differentially in TK+/+ and TK-/- Kupffer cells basally as well as after HGFL and LPS treatment. Interestingly, our studies identified Mefv, a gene that codes for the anti-inflammatory protein pyrin, as an HGFL-stimulated Ron-dependent ***, lipocalin 2, a proinflammatory gene, which is induced by LPS, was significantly suppressed by HGFL *** results were validated by qRT-PCR studies on Kupffer cells treated with LPS and ***: The studies herein suggest a novel mechanism whereby HGFL-induced Ron receptor activation promotes the expression of anti-inflammatory genes while inhibiting genes involved in inflammation with a net effect of diminished inflammation in macrophages.

关键词： Mst1R Mefv Lcn2 Met receptor Kupffer cells macrophages