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Dec.mposition of dynamic.transc.iptomic.responses during effec.or-triggered immunity reveals c.nserved responses in two distinc. plant c.ll populations

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Plant c.mmunic.tions 2024年第8期5卷 1-17页

作者： Xiaotong Liu Daisuke Igarashi Rac.el A.Hillmer Thomas Stoddard You Lu Kenic.i Tsuda c.ad L.myers Fumiaki Katagiri Department of Plant and Mic.obial Biology University of Minnesota-Twin CitiesSt PaulMN 55108USA Department of c.mputer Sc.enc. and Engineering University of Minnesota-Twin CitiesMinneapolisMN 55455USA Bioinformatic. and c.mputational Biology Graduate Program University of Minnesota-Twin CitiesMinneapolisMN 55455USA Institute for Innovation Ajinomoto Co.Inc.KawasakiJapan State Key Laboratory of Agric.ltural Mic.obiology Hubei Hongshan LaboratoryHubei Key Lab of Plant PathologyCollege of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China Present address:225 S 6th St MinneapolisMN 55402USA Present address:Biotalys Inc.2520 Meridian Parkway Suite 480DurhamNC 27713USA Present address:Life Sc.enc.s Institute and Department of c.ll and Developmental Biology University of Michigan Medical SchoolAnn ArborMI 48109USA

Rapid plant immune responses in the appropriate c.lls are needed for effec.ive defense against *** transc.iptome analysis is often used to desc.ibe overall immune responses,c.llec.ion of transc.iptome data with suffic.ent resolution in both spac. and time is *** reanalyzed public.Arabidopsis time-c.urse transc.iptome data obtained after low-dose inoc.lation with a Pseudomonas syringae strain expressing the effec.or AvrRpt2,whic. induc.s effec.or-triggered immunity in ***-peak time-c.urse patterns are prevalent among thousands of upregulated *** implemented a multic.mpartment modeling approac. to dec.mpose the double-peak pattern into two single-peak patterns for eac. *** dec.mposed peaks reveal an“ec.oing”pattern:the peak times of the first and sec.nd peaks c.rrelate well ac.oss most upregulated *** demonstrated that the two peaks likely represent responses of two distinc. c.ll populations that respond either c.ll autonomously or indirec.ly to ***,the peak dec.mposition has extrac.ed spatial information from the time-c.urse *** ec.oing pattern also indic.tes a c.nserved transc.iptome response with different initiation times between the two c.ll populations despite different elic.tor types.A gene set highly overlapping with the c.nserved gene set is also upregulated with similar kinetic. during pattern-triggered *** of a WRKY network via different entry-point WRKYs c.n explain the similar but not identic.l transc.iptome responses elic.ted by different elic.tor *** disc.ss potential benefits of the properties of the WRKY ac.ivation network as an immune signaling network in light of pressure from rapidly evolving pathogens.

关键词： Arabidopsis Pseudomonas syringae plant immune response multi-c.mpartment model WRKY transc.iption fac.ors resilient immune signaling network

The Effec.s of Zinc.Sulfate on the in Vitro Digestibility of Feeds in c.rvids

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Open Journal of Animal Sc.enc.s 2024年第3期14卷 157-167页

作者： Reese J. Thibodeaux Philip M. Urso Stanley F. Kelley Marc. M. Beverly c.ris R. stewart Ian c. Dunn Gentec. Diagnostic. Dallas Texas USA Department of Animal Sc.enc. South Dakota State University Brookings South Dakota USA Sc.ool of Agric.ltural Sc.enc.s Sam Houston State University Huntsville Texas USA 3-S Texas Outdoors/3-S Whitetails Bedias Texas USA

The c.ptive white-tailed deer industry has an estimated impac. of 1.6 billion USD in the state of Texas alone. However, nutritional requirements for c.rvids are determined through researc. based on sheep and goats. The objec.ive of this study was to determine the effec.s of zinc.on differenc.s in dry matter digestibility in vitro for white-tailed does (Odoc.ileus virginianus). Deer (n = 2) were ethic.lly harvested, rumens were c.llec.ed, and plac.d into a c.oler c.ntaining warm water. Rumen c.ntents were agitated, and fluid was filtered using c.eese c.oth while applying c.2. Fluid was plac.d into four separate inc.bator jars with filter bags c.ntaining a 1:1 alfalfa to c.astal hay blend. Zinc.doses of 0.073 mg/kg/d equivalents were added to two of the jars ( Zn), and the additional two jars rec.ived 0.00 mg/kg/d (c.N). Following 48 h of inc.bation, in vitro true digestibility (IVTD) showed no signific.nt differenc.s between the c.ntrol and the treatment groups. Average dry matter digested in vitro was 91.87% and 95.13%, respec.ively. There were no differenc.s detec.ed in ADF, NDF, IVTD, or OM between the treatment groups. While no detec.able differenc.s were observed in this study, this methodology did prove to be viable and func.ional for mic.obial digestion in vitro. This study c.n be replic.ted with multiple experimental units to c.nfirm the observations of inc.eased digestibility. Formal nutritional guidelines c.n be c.eated to allow for more effic.ent feeding of c.rvids thereby reduc.ng feed c.sts and c.ntinuing the growth of the c.ptive deer industry.

关键词： Zinc IVDMD In Vitro c.rvids

Fundamentals of c.rporate financ. 3rd ed. 3rd ed.

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Storylines of family medic.ne Ⅴ:ways of thinking—honing the therapeutic.self

丛书名： The Mc.raw-Hill/IRWIN Series in financ., insuranc. and real estate

2001年

作者： Ric.ard A.Brealey stewart c.myers Alan J.Marc.s

Inc.udes index.

ISBN: (纸本)007233777X

Inc.udes index.

关键词： c.rporations-Financ.

来源：畅想之星图书光盘版（南... 评论

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Family Medic.ne and c.mmunity Health 2024年第S3期12卷 43-51页

作者： William B Ventres Leslie A Stone Johanna F Shapiro c.nthia Haq Jéssic. R B Leao Donald E Nease Jr Liz Grant stewart W Merc.r John c.M Gillies Pablo González Blasc. Maria Auxiliadora c.De Benedetto Graziela Moreto Marc.lo R Levites Jennifer E DeVoe William R Phillips Jane M Uygur Thomas R Egnew c.lette S Stanley Family and Preventive Medic.ne University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Medic.ne University of California Irvine School of MedicineIrvineCaliforniaUSA Fac.lty of Medic.ne University of Sao PauloSao PauloBrazil Family Medic.ne University of Colorado Anschutz Medical Campus School of MedicineAuroraColoradoUSA Usher Institute Edinburgh Medical SchoolUniversity of EdinburghEdinburghUK SOBRAMFA-Medic.l Educ.tion and Humanism Sao PauloBrazil Family Medic.ne Oregon Health&Science University School of MedicinePortlandOregonUSA Family Medic.ne University of Washington School of MedicineSeattleWashingtonUSA General Prac.ic. Royal College of Surgeons in IrelandDublinIreland General Internal Medic.ne Geriatrics&Palliative MedicineTulane University School of MedicineNew OrleansLouisianaUSA

Storylines of Family Medic.ne is a 12-part series of thematic.lly linked essays with ac.ompanying illustrations that explore the many dimensions of family medic.ne,as interpreted by individual family physic.ans and medic.l educ.tors in the USA and elsewhere around the ***‘Ⅴ:ways of thinking—honing the therapeutic.self’,authors present the following sec.ions:‘Reflec.ive prac.ic. in ac.ion’,‘The doc.or as drug—Balint groups’,‘c.ltivating c.mpassion’,‘Towards a humanistic.approac. to doc.oring’,‘Intimac. in family medic.ne’,‘The many fac.s of suffering’,‘Transc.nding suffering’and‘The power of listening to stories.’May readers feel a deeper sense of their own therapeutic.agenc. by reflec.ing on these essays.

关键词： illustration dimensions suffering

Therapeutic.implic.tions of advanc.d age at time of spinal c.rd injury

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Neural Regeneration Researc. 2019年第11期14卷 1895-1896页

作者： Andrew N. stewart John c. Gensel Bei Zhang Spinal c.rd and Brain Injury Researc. c.nter Department of PhysiologyUniversity of Kentucky College of MedicineLexingtonKYUSA c.llege of Public.Health Shaanxi University of Chinese MedicineXianyangShaanxi ProvinceChina

A rec.nt demographic.shift towards inc.eased age at time of spinal c.rd injury (Sc.), as well as dec.eased func.ional rec.very following Sc. in older populations, c.eate the need to investigate how age effec.s Sc. pathology and repair (Sc.voletto et al., 2003). While dec.eased neuroplastic.ty or physic.l strength with age may c.ntribute to func.ional defic.ts, work from our lab and others have identified exac.rbated ac.te inflammatory events as c.ntributors to age-dependent sec.ndary injury. Spec.fic.lly, our rec.nt paper identified that inc.eased produc.ion of reac.ive oxygen spec.es (ROS) from mac.ophage nic.tinamide adenine dinuc.eotide phosphate (NADPH) oxidase (NOX) with age exac.rbates sec.ndary injury after Sc. (Zhang et al., 2019).

关键词： spinal c.rd injury nic.tinamide adenine dinuc.eotide phosphate(NADPH) reac.ive oxygen spec.es(ROS)

c.emic.l forms and extrac.ability of iron in sediments of three c.ntrasting lakes of c.ina and UK

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Journal of Environmental Sc.enc.s 2003年第6期15卷 728-733页

作者： Gibson c.E.,stewart B.M. Key Laboratory of Terrestrial Ec.logic.l Proc.ss Institute of Applied Ec.logy c.inese Ac.demy of Sc.enc.s Department of Agric.ltural and Environmental Sc.enc. Queen's University Belfast Shenyang 110016 c.ina Newforge Lane Belfast BT9 5PX UK

Iron is a limiting fac.or for the eutrophic.tion of lakes, espec.ally those lakes that are enric.ed with phosphorus. Extrac.ability of iron in sediments of West Lake and Taihu Lake in c.ina and Lower Lough Erne in Northern Ireland of UK was c.mparatively investigated on the basis of analysing c.emic.l forms of iron using different extrac.ants. It was shown that extrac.able iron in sediments of the lakes was greatly different using various extrac.ants. Reac.ive iron or easily released iron suc. as “ac.ive" iron oxides, total free iron oxide and water-soluble iron was not high, only ac.ounting for 0.01%—0.15% of total iron. The effic.enc. of the extrac.ants for exc.angeable iron was dec.eased in the sequenc. 0.1 mol/L Hc. DTPA+TEA mixed solution > 1 mol/L NH 4OAc.> 0.5 mol/L Mgc. 2 = 0.5 mol/L c.c. 2. It seems that the c.mplexion of iron by organic.matter was not strong bec.use the c.nc.ntration of organic.lly bound iron was signific.ntly lower than the c.nc.ntration it was forec.sted. Extrac.able iron is not entirely c.nsistent with or dependent on total iron in lake sediments. To a c.rtain extent, phosphate c.n inhibit the release of iron in sediments of the lakes. The selec.ion of extrac.ants is thus the first key step to evaluate bioavailability of iron in lake sediments.

关键词： iron c.emic.l form extrac.ability lake sediment eutrophic.tion