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Extraintestinal heterotopic gastric tissue simulating acute appendicitis

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World Journal of Gastroenterology 2008年第14期14卷 2268-2269页

作者： Elizabeth Bender steven p Schmidt Department of Surgery and Division of Surgical Research Summa Health System Akron Ohio 44304 United States

We describe the case of a 68-year-old otherwise healthy male who presented to our emergency room with signs and symptoms of acute appendicitis. Exploratory surgery revealed a normal appendix. Further examination revealed an enlarged lymph node-like mass of tissue near the appendix, in the ileocecal mesentery. This mass was removed and was found to be inflamed heterotopic gastric tissue. Although reports of heterotopic gastric tissue in the literature are common, we believe that this case represents the first report of inflamed heterotopic gastric tissue simulating appendicitis.

关键词： Heterotopic gastric mucosa Acute appendicitis

MicroRNA regulation of innate immune responses in epithelial cells

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Cellular & Molecular Immunology 2011年第5期8卷 371-379页

作者： Rui Zhou steven p O’Hara Xian-Ming Chen Department of Microbiology and Immunology Creighton University School of MedicineOmahaNEUSA Division of Gastroenterology and Hepatology Department of Internal MedicineMayo Clinic College of MedicineRochesterMNUSA

Mucosal surface epithelial cells are equipped with several defense mechanisms that guard against *** studies indicate that microRNAs(miRNAs)mediate post-transcriptional gene suppression and may be a critical component of the complex regulatory networks in epithelial immune *** of miRNA genes in epithelial cells can be elaborately controlled through pathogen recognition receptors,such as Toll-like receptors(TLRs),and associated nuclear factor kappaB(NF-kB)and mitogen-activated protein kinase(MApK)pathways,and ultimately nuclear transcription factor associated-transactivation and *** of these intracellular signaling pathways may also modulate the process of miRNA ***,miRNAs may modulate epithelial immune responses at every step of the innate immune network,including production and release of cytokines/chemokines,expression of adhesion and costimulatory molecules,shuttling of miRNAs through release of exosomes and feedback regulation of immune ***,miRNAs act as critical regulators to the fine-tuning of epithelial immune responses.

关键词： epithelial cells immune responses miRNAs posttranscriptional regulation TLRs

Metalorganic chemical vapor deposition of InN quantum dots and nanostructures

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Light(Science & Applications) 2021年第8期10卷 1409-1420页

作者： Caroline E.Reilly Stacia Keller Shuji Nakamura steven p.DenBaars Materials University of CaliforniaSanta BarbaraCA 93106USA Electrical and Computer Engineering University of CaliforniaSanta BarbaraCA 93106USA

Using one material system from the near infrared into the ultraviolet is an attractive goal,and may be achieved with(ln,AI,Ga)***Ⅲ-N material system,famous for enabling blue and white solid-state lighting,has been pushing towards longer wavelengths in more recent *** a bandgap of about 0.7 eV,InN can emit light in the near infrared,potentially overlapping with the part of the electromagnetic spectrum currently dominated byⅢ-As andⅢ-p *** has been the case in these otherⅢ-V material systems,nanostructures such as quantum dots and quantum dashes provide additional benefits towards optoelectronic *** the case of InN,these nanostructures have been in the development stage for some time,with more recent developments allowing for InN quantum dots and dashes to be incorporated into larger device *** review will detail the current state of metalorganic chemical vapor deposition of InN nanostructures,focusing on how precursor choices,crystallographic orientation,and other growth parameters affect the *** optical properties of InN nanostructures will also be assessed,with an eye towards the fabrication of optoelectronic devices such as light-emitting diodes,laser diodes,and photodetectors.

关键词： optoelectronic quantum chemical

Accessing acute medical care to protect health: the utility of community treatment orders

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General psychiatry 2022年第6期35卷 379-388页

作者： steven p Segal Leena Badran Lachlan Rimes School of Social Welfare University of CalifomiaBerkeleyBerkeleyCaliforniaUSA Social Work The University of Melboume Faculty of Medicine Dentistry and Health SciencesMelboumeVictoriaAustalia Victoria Department of Health and Human Services(VDHHS) MelboumeVictoriaAustralia

Background The conclusion that people with severe mental llness require involuntary care to protect their health(including threats due to physical-nonpsychiatric-illness)is challenged by findings indicating that they often lack access to general healthcare and the assertionthat theywould access suchcarevoluntarily if available and ***,Australia's single-payer healthcare system provides accessible medical treatment;therefore,it is an excellent context in which to test these *** study replicates aprevious investigation in considering whether,in Australia's easy-access singlepayer healthcare system,patients placed on community treatment orders,specifically involuntary community treatment,are more likelyto access acute medical care addressing potentially life-threatening physical illnesses than voluntary patients with and without severe mental *** Replicating methods used in 2000-2010,for the years 2010-2017,this study compared the acute medical care access of three new cohorts:7826 hospitalised patientswith severemental illnesswho received a post-hospitalisation,community treatment order;13896 patients with severe mental illness released from the hospital without a community treatment order and 12101outpatients who were never psychiatrically hospitalised(individuals with less morbidity risk who were not considered to have severe mental llness)during periods when they were under versus outside community mental health *** regression was used to determine the influence of community-based community mental health supervision and the type of community mental health supervision(community treatment order vs non-community treatment order)on the likelihood of receiving an initial diagnosis of a life-threatening physical illness *** Validating their shared elevated morbidity risk,43.7%and 46.7%,respectively,of each hospitalised cohort(community treatment order and non-community treatment order pati

关键词： diagnosis treatment illness

Sport Concussion—The Field Evaluation

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中国运动医学杂志 2010年第1期29卷 90-93页

作者： steven p.Broglio Neurotrauma Research Laboratory University of Illinois at Urbana-Champaign

Despite a significant increase in the understanding of concussion,this injury remains one of the most complex and poorly *** manuscript will outline a step-by-step process for concussion evaluation to ensure subtle signs and symptoms are not *** systematic approach includes a thorough athlete history,observation of mannerisms,and palpation of the relevant anatomical *** tests for neurostatus and postural control follow with manual muscle testing of theneck musculature as ***,all athletes shouldbe subjected to functional *** conjunction with the clinical examination outlined here,the return to play decision should be made under the consultation of a physician.

关键词：脑振荡临床签定患者临床分析

Exposing the urban continuum:implications and crosscomparison from an interdisciplinary perspective

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International Journal of Digital Earth 2020年第1期13卷 22-44页

作者： Johannes H.Uhl Hamidreza Zoraghein Stefan Leyk Deborah balk Christina Corbane Vasileios Syrris Aneta JFlorczyk Department of Geography University of Colorado BoulderBoulderCOUSA National Center for Atmospheric Research(NCAR) BoulderCOUSA CUNY Institute for Demographic Research and Baruch College City University of New YorkNew York CityNYUSA European Commission Joint Research Centre(JRC)IspraItaly

There is an increasing availability of geospatial data describing patterns of human settlement and population such as various global remote-sensing based built-up land layers,fine-grained census-based population estimates,and publicly available cadastral and building footprint *** development constitutes new integrative modeling opportunities to characterize the continuum of urban,peri-urban,and rural settlements and ***,little research has been done regarding the agreement between such data products in measuring human presence which is measured by different proxy variables(*** of built-up structures derived from different remote sensors,census-derived population counts,or cadastral land parcels).In this work,we quantitatively evaluate and cross-compare the ability of such data to model the urban continuum,using a unique,integrated validation database of cadastral and building footprint data,*** data,and three different versions of the Global Human Settlement Layer(GHSL)derived from remotely sensed *** identify advantages and shortcomings of these data types across different geographic settings in the U.S.,which will inform future data users on implications of data accuracy and suitability for a given application,even in data-poor regions of the world.

关键词： Built-up surfaces Global Human Settlement Layer(GHSL) Sentinel-1 Landsat agreement assessment urban modeling cadastral parcel data U.S.census data

Kaempferia parviflora ethanol extract improves self-assessed sexual health in men:a pilot study

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Journal of Integrative Medicine 2018年第4期16卷 249-254页

作者： Richard A.Stein Kira Schmid Jowell Bolivar Andrew G.Swick steven V.Joyal steven p.Hirsh Life Extension 3600 West Commercial BlvdFort tauderdaleFL 33309USA Life Extension Clinical Research Inc.5990 North Federal HighwayFort LauderdaleFL 33308USA

Background： Sexual health positively correlates with overall wellbeing. Existing therapeutics to enhance male sexual health are limited by factors that include responsiveness, adherence and adverse effects. As the population ages, safe and effective interventions that preserve male sexual function are needed. published research suggests that various preparations of Kaempferia parviflora, a plant in the Zingiberaceae （ginger） family, support cardiovascular health and may ameliorate erectile function. Objective： The aim of this study was to examine the effects of KaempMaxTM, an ethanol extract of the K. parvi]lora rhizome, on erectile function in healthy middle-aged and older men. Design, setting, participants and interventions： We conducted an open-label, one-arm study on 14 generally healthy males aged 50-68 years with self-reported mild erectile dysfunction, who were not using pre- scription treatments. participants took 100 mg KaempMaxTM daily for 30 days. Main outcome measures： Evaluations were conducted at baseline and on the final study assessment. primary efficacy analyses included the International Index of Erectile Function （IIEF）; secondary efficacy analyses included the Global Assessment Question about erectile function. Results： Thirteen participants completed the 30-day study. Supplementation with KaempMaxTM resulted in statistically significant improvements in erectile function, intercourse satisfaction and total scores on the IIEF questionnaire. KaempMaxTM was well tolerated and exhibited an excellent safety profile. Conclusion： Our results suggest that KaempMaxTM may improve erectile function in healthy middle-aged and older men. While the effects were not as pronounced as what might be seen with prescription med- ication, most participants found them satisfactory. Additional, longer and placebo-controlled clinical tri- als will be needed. Trial registration： *** identifier Ncr03389867.

关键词： Sexual health Kaempferia parviflom Complementary therapies KaempMax^TM Global Assessment QuestionInternational Index of Erectile Function

Citizenship Education under Discourses of Nationalism,Globalization,and Cosmopolitanism:Illustrations from China and the United States

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Frontiers of Education in China 2011年第4期6卷 602-619页

作者： steven p.CAMICIA Juanjuan ZHU Emma Eccles Jones College of Education and Human Services School of Teacher Education and LeadershipUtah State UniversityLoganUT 84322-2805USA

The authors,one from China and one from the United States,present a theoretical framework for understanding the discursive fields of citizenship education as composed,in large part,of the discourses of nationalism,globalization,and *** framework is illustrated by examples from citizenship education in China and the United *** education in these examples is largely influenced by the discourse of *** discursive fields are fractured,context-specific,and *** conclusion,the authors call for awareness of how these discourses operate,and propose that the discourses of globalization and cosmopolitanism merge and strengthen within citizenship *** effect could be a new citizenship education that is responsive to the current needs of local and global democratic communities.

关键词： citizenship education nationalism globalization cosmopolitanism

N-acetylcysteine treats intravenous amiodarone induced liver injury

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World Journal of Gastroenterology 2015年第9期21卷 2816-2819页

作者： Matthew L Mudalel Kartikeya p Dave James p Hummel steven F Solga Department of Medicine Division of GastroenteorlogySt. Luke’s University Hospital and Temple School of MedicineBethlehemPA 18015United States Department of Medicine Montefiore Medical CenterBronxNY 10461United States Department of Medicine Division of Cardiology University of North Carolina Chapel Hill NC 27514United States

We report a case of intravenous(IV) amiodarone drug induced liver injury(DILI).The patient received IV N-acetylcysteine(NAC) which resulted in a rapid improvement in liver *** the specific mechanisms for the pathogenesis of IV amiodaroneDILI and the therapeutic action of IV NAC are both unknown, this case strongly implies at least some *** IV amiodarone is indicated for the treatment of serious cardiac arrhythmias in an intensive care unit setting, some degree of ischemic hepatitis is likely a cofactor in most cases.

关键词： N-acetylcysteine Amiodarone Drug induced liver inj