检索结果-南通市图书馆

Reservoir Potential of Silurian Carbonate Mud Mounds in the Southern Sichuan Basin,Central China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Geologica Sinica(English Edition) 2006年第5期80卷 684-692页

作者： ZHAO Wenzhi YANG Xiaoping steve KERSHAW ZHANG Baomin Research Institute of Petroleum Exploration and Development CNPC Xueyuan Road Beijing 100083 China Department of Geography and Earth Science Brunel University Uxbridge UB8 3PH UK

Lower Silurian mud mounds of the Shinuilan Formation, located in the southern Sichuan Basin, China, have developed in open shelf settings in deeper water than shallow-water reef-bearing limestones that occur in the region. An integration of the outcrop, drill data and seismic profiles show that contemporaneous faults have controlled the boundary and distribution of the sedimentary facies of Lower Silurian rocks in the southern Sichuan Basin. Mounds appear to have developed in the topographic lows formed by synsedimentary faulting, on the sheff of the Yangtze Platform. Average mound thickness is 20 m, maximum 35 m. Mounds are composed mainly of micrite, possibly microbially bound, and are overlain by shales. Mound tops are preferentially dolomitized, with the Mg^2＋ source probably from the clay content of the mound-top carbonate. Microfacies analysis and reconstruction of the diagenetic history reveal that the mound tops have higher porosity, and are gas targets; in contrast, mound cores and limbs show pores filled by three generations of calcite cement, and therefore have a low gas potential.

关键词： sedimentary facies reservoir mud mound Early Silurian Sichuan Basin China

Applications of next-generation sequencing to the study of biological invasions

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2015年第3期61卷 488-504页

作者： Marc RIUS steve BOURNE Harry Guy HORNSBY Mark A. CHAPMAN Ocean and Earth Science National Oceanography Centre Southampton University of Southampton SO 14 3ZH UK Centre for Biological Sciences Life Sciences Building 85 University of Southampton Southampton SO 17 1B J UK

Through the widespread implementation of next-generation sequencing （NGS）, analyses of the whole genome （the entire DNA content） and the whole transcriptome （the genes being expressed） are becoming commonplace. NGS enables the analysis of a vast amount of previously unattainable genetic information. Despite this potential, NGS has yet to be widely imple- mented in genetic studies of biological invasions. The study of the genomic causes and consequences of biological invasions al- lows a deeper understanding of the molecular mechanisms underpinning the invasion process. In this review, we present a brief introduction to NGS followed by a synthesis of current research in the genomics and transcriptomics of adaptation and coloniza- tion. We then highlight research opportunities in the field, including：（1） assembling genomes and transcriptomes of non-model organisms, （2） identifying genomic regions and candidate genes underlying evolutionary processes, and （3） studying the adaptive role of gene expression variation. In particular, because introduced species face a broad range of physiological and biotic chal- lenges when colonizing novel and variable environments, transcriptomics will enable the study of gene regulatory pathways that may be responsible for acclimation or adaptation. To conclude, we identify a number of research approaches that will aid our fu- ture understanding of biological invasions

关键词： Exotic species Genomics Genotype-environment interactions Invasive species Invasion genetics Invasion route Non-indigenous species Non-native species

Fabrication and characteristic detection of graphene nanoelectrodes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2014年第10期57卷 1950-1955页

作者： XIE ShuangXi LIU ZengLei JIAO NianDong TUNG steve LIU LianQing State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences University of Chinese Academy of Sciences Department of Mechanical Engineering University of Arkansas

Graphene has the advantages of high electrical conductivity,high heat conductivity,and low noise,which makes it a potential option for integrated circuits interconnection and *** this paper,we present a novel fabrication method for graphene nanoeletrodes with ***,graphene grown by chemical vapor deposition(CVD)is assembled to a chip with ***,an atomic force microscopy(AFM)based mechanical cutting method is developed to cut the graphene into nanoribbons and nanoeletrodes with *** the electronic property of a single nanodot is characterized using the garphene nanoelectrodes,demonstrating the effectiveness of the graphene *** fabricated graphene nanoeletrode pairs can be used as probes to detect single molecule in micro-environment,and show an attractive prospect for future molecular electronics applications.

关键词： atomic force microscopy graphene nanoelectrodes nanogap molecular electronics

Host cell protein quantification workflow using optimized standards combined with data-independent acquisition mass spectrometry

在线全文

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2023年第5期13卷 494-502页

作者： steve Hessmann Cyrille Chery Anne-Sophie Sikora Annick Gervais Christine Carapito BioOrganic Mass Spectrometry Laboratory(LSMBO) IPHC UMR 7178University of StrasbourgCNRSProFI-FR2048Strasbourg67000France Department of Analytical Development Sciences for Biologicals UCB Pharma S.A.Braine l'Alleud1420Belgium

Monitoring of host cell proteins(HCPs)during the manufacturing of monoclonal antibodies(mAb)has become a critical requirement to provide effective and safe drug ***-linked immunosorbent assays are still the gold standard methods for the quantification of protein ***,this technique has several limitations and does,among others,not enable the precise identification of *** this context,mass spectrometry(MS)became an alternative and orthogonal method that delivers qualitative and quantitative information on all identified ***,in order to be routinely implemented in biopharmaceutical companies,liquid chromatography-MS based methods still need to be standardized to provide highest sensitivity and robust and accurate ***,we present a promising MS-based analytical workflow coupling the use of an innovative quantification standard,the HCP Profiler solution,with a spectral library-based data-independent acquisition(DIA)method and strict data validation *** performances of the HCP Profiler solution were compared to more conventional standard protein spikes and the DIA approach was benchmarked against a classical datadependent acquisition on a series of samples produced at various stages of the manufacturing *** we also explored spectral library-free DIA interpretation,the spectral library-based approach still showed highest accuracy and reproducibility(coefficients of variation<10%)with a sensitivity down to the sub-ng/mg mAb ***,this workflow is today mature to be used as a robust and straightforward method to support mAb manufacturing process developments and drug products quality control.

关键词： Host cell proteins Absolute quantification standards Data-independent acquisition

The synergistic effect of 3D-printed microscale roughness surface and nanoscale feature on enhancing osteogenic differentiation and rapid osseointegration

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2021年第4期63卷 18-26页

作者： Hui Wang Jiaqiang Liu Chengtao Wang steve Guofang Shen Xudong Wang Kaili Lin Department of Oral and Cranio-maxillofacial Surgery Shanghai Ninth People’s HospitalCollege of StomatologyShanghai Jiao Tong University School of MedicineNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of Stomatology&Shanghai Research Institute of StomatologyShanghai200011China School&Hospital of Stomatology Tongji UniversityShanghai Engineering Research Center of Tooth Restoration and RegenerationShanghai200072China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai200240China Shanghai University of Medicine&Health Sciences Shanghai201318China

Personalized precision therapy and rapid osseointegration are the main development directions of dental implants.3 D printing is a vital advanced manufacturing technology for personalized precision ***,the osteogenesis of the 3 D printed Ti6 Al4 V implants is *** the bionic perspective,the hierarchical micro/nano-topography can mimic the microenvironment of the multilevel structure of natural bone tissue and may endow the implant surface with superior *** the present study,the hierarchical micro/nano-topography was successfully fabricated by construction the nanoscale feature on 3 D printed microscale roughness surface of 3 D-printed Ti6 Al4 V implants by alkali-heat treatment and hydrothermal *** the cell biological responses in vitro and osseointegration performance in vivo were systematically *** hierarchical micro/nano-topography evidently increased the roughness,improved the hydrophilicity and accelerated the hydroxyapatite deposition and mineralization,which significantly enhanced the adhesion,differentiation and extracellular matrix mineralization of bone marrow derived mesenchymal stromal cells(BMSCs).Most importantly,the hierarchical micro/nano-topography on 3 D-printed implants facilitated the new bone formation and rapid osseointegration in *** study suggested that 3 D-printed implant with micro/nano-topography may be a promising candidate to be applied in orthopedic field to meet the need of customized therapy and rapid osseointegration.

关键词： rapid roughness topography

Light Perception:A Matter of Time

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2020年第3期13卷 363-385页

作者： Sabrina E.Sanchez Matias L.Rugnone steve A.Kay Department of Neurology Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

Optimizing the perception of external cues and regulating physiology accordingly help plants to cope with the constantly changing environmental conditions to which they are *** array of photoreceptors and intricate signaling pathways allow plants to convey the surrounding light information and synchronize an endogenous timekeeping system known as the circadian *** biological clock integrates multiple cues to modulate a myriad of downstream responses,timing them to occur at the best moment of the day and the ***,the mechanism underlying entrainment of the light-mediated clock is not *** review addresses known interactions between the light-signaling and circadian-clock networks,focusing on the role of light in clock entrainment and known molecular players in this process.

关键词： circadian clock light signaling Arabidopsis thaliana light entrainment photoreceptors signal integration

Research on numerical emulator of mine methane and coal dust explosion

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Coal Science & Engineering(China) 2008年第3期14卷 447-452页

作者： CAI Zhou-quan Niu steve Chongqing Institute of Coal Science Academy Chongqing 400000 China Shaw University Raleigh NC 27601 USA

The mathematical physics model of mine methane and coal dust explosion propagation was established in the research,by using continuous phase,combustion,par- ticulate equations of mathematical *** upon the data from mine methane drainage roadway explosion,and mine methane and coal dust explosion propagation ex- perimental studies,the numerical emulator system of mine methane and coal dust explo- sion software was developed by using prevalent flow simulation platform,which can be used to simulate the explosion accidents process *** addition,the system can also be used to determine whether coal dust involved in the explosion,and to simulate accurately the transition from deflagration to detonation in methane explosion,propagation velocity of explosion shock,attenuation pattern,and affected area of explosion.

关键词： mine methane and coal dust explosion continuous phase mathematica physics equations particulate phase numerical emulator system

Special report on the fourth international conference on countermeasures to urban heat island （4th IC2UHI Conference） in Singapore

在线全文

学校读者我要写书评

暂无评论

Frontiers of Architectural Research 2016年第4期5卷 508-510页

作者： Wong Nyuk Hien steve Kardinal Jusuf School of Design and Environment Department of Building National University of SingaporeSingapore 117566 Singapore Engineering Cluster Singapore Institute of Technology Singapore 138683 Singapore

Initiated by Prof. Hashem Akbari, international conference on countermeasures to urban heat island （IC2UHI Conference） was first held in Tokyo, Japan in year 2006. Subsequently, it was held in Berkeley, USA and Veni...

关键词：

Guest editorial: Machine Learning in Wireless Networks

在线全文

学校读者我要写书评

暂无评论

CAAI Transactions on Intelligence Technology 2021年第2期6卷 133-134页

作者： Anil Kumar Budati steve S.H.Ling Department of Electronics and Communication Engineering Gokaraju Rangaraju Institute of Engineering and TechnologyHyderabadIndia School of Biomedical Engineering University of Technology SydneySydneyNew South WalesAustralia

This dedicated Special Section on Machine Learning in Wireless Networks aims to provide improved knowledge for state-of-the-art worldwide R&D communities in wireless networks and machine learning(ML)*** aims to do so by calling for novel formulations,innovative techniques,and optimised solutions to highlight the key issues related to these problems in a forum for shared research and ideas.

关键词： Wireless wireless formulation