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Effects of Tecar Therapy on Adipose Tissue: Clinical Trial

Journal of Biosciences and Medicines 2022年第4期10卷 169-180页

作者： Patrícia Froes Meyer Rodrigo Marcel Valentim Da Silva Eneida De Morais Carreiro Fábio dos Santos Borges stephany queiroga Felice Picariello Centro Universitario do Rio Grande do Norte UNI-RN Natal Brazil Universidade Federal do Rio Grande do Norte UFRN Natal Brazil Estácio de Sa University Rio de Janeiro Brazil Potiguar University UnP Natal Brazil University of the Study of Naples Federico II Nápoles Itália

Introduction: Localised adiposity is one of the leading aesthetic alteration complaints. Tecar therapy has been used in clinical practice for the treatment of fat located in the abdominal region. Objective: The objective is to analyse the effect of Tecar therapy on abdominal adiposity. Methodology: This is a clinical trial in which the participants were 32 female volunteers who have flaccidity and fat located in the abdominal region. The volunteers were divided into three groups, which respectively received applications of the capacitive mode, the resistive mode, and combined therapy of the two modalities. We have performed ten applications and analysed the anthropometric measures, the ultrasonography of the adipose layer, and the level of satisfaction. Results: All groups presented a reduction in perimetry compared to the baseline (p = 0.001). The ultrasonography showed a significant reduction in the combined therapy group compared to the baseline (p = 0.04 and p = 0.03). The level of satisfaction was good in all groups, with few adverse responses. In the bodyweight and percentage of fat analyses, we observed an increase in measurements, probably due to the restriction measures related to the new coronavirus pandemic in 2020. Conclusion: In this present study, we have concluded that Tecar therapy resulted in a reduction of the fat located in the abdominal region.

关键词： Radiofrequency Abdominal Fat Ultrasonography

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Comparative Study of Collagen Stimulation Using Semi-Ablative and Non-Ablative Radiofrequency

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Journal of Biosciences and Medicines 2022年第6期10卷 79-89页

作者： Patrícia Froes Meyer Rodrigo Marcel Valentim da Silva Eneida De Morais Carreiro Rafaella Rêgo Maia stephany Luanna queiroga Farias Ciro Dantas Soares Yuri Alexander Afonso Gustavo Felipe Pasqual Silene Bazi Ribeiro Roberto Tiago Alves Pinheiro University Centre of Rio Grande do Norte (UNIRN) Natal Brazil Estácio de Sá University Natal Brazil Federal University of Rio Grande do Norte Natal Brazil Potiguar University (UNP) Natal Brazil Campinas State University (UNICAMP) Campinas Brazil Brazilian Society of Plastic Surgery Brazil FSG University Centre of Serra Gaúcha Caxias do Sul Brazil MARC Institute Miami USA

Objective: Comparison between semi-ablative and non-ablative radiofrequency for collagen stimulation. Method: Three volunteers with scheduled surgical procedures of abdominoplasty were selected. After the evaluation, the abdominal area was divided into three quadrants, with the right region receiving monopolar non-ablative radiofrequency (RF) application. In contrast, the left region received fractionated radiofrequency (FRF) application, using three different needle sizes (0.5, 1.5, and 3.0 mm), and the intermediate area was kept as a control. After 24 hours, surgery was performed, and the skin flaps were collected for histological and immunohistochemical analyses. Results: An increase in total collagen and type I collagen was observed in the treated groups. There was also an increase in the expression of COX-2, CD68 positive cells (macrophages), and lymphocyte markers (CD3, CD20, and NK-CD57). Furthermore, it was seen that only the use of 3.0-mm needles kept the channels open in the superficial tissue after 24 hours. There were no significant differences between the modalities. Conclusion: Non-ablative and sub-ablative radiofrequency have positive and effective results for flaccidity, demonstrating the success in collagen production. Furthermore, this study is the first to present channel opening and permanence time, which are important to optimize the action of drug delivery.

关键词： Collagen Flaccidity Radiofrequency Drug Delivery

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Effect of Microfocused Ultrasound on Facial Rejuvenation: Clinical and Histological Evaluation

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Journal of Biosciences and Medicines 2021年第7期9卷 112-125页

作者： Patricia Froes Meyer Michelle Meleck Fabio dos Santos Borges Esteban Fortuny stephany Luanna queiroga Farias Felipe Alexander Caldas Afonso Ciro Dantas Soares Eneida de Morais Carreiro Rodrigo Marcel Valentim da Silva André Luiz Miranda Barbosa Federal University of Rio Grande do Norte (UFRN) Natal Brazil University Centre of Rio Grande do Norte (UNI-RN) Natal Brazil Michelle Meleck Advanced Aesthetics S&atilde o Paulo Brazil Estácio de Sá University Rio de Janeiro Brazil Universidad Finis Terrae Santiago Chile Potiguar University (UNP) Natal Brazil Campinas State University (UNICAMP) Campinas Brazil Fellow da West Virginia University Morgantown USA

Introduction: Micro focused ultrasound (MFU) is formed by mechanical waves emitted in a focused manner, concentrating thermal energy on a certain point or region, promoting a clinical improvement in wrinkles. Objective: evaluate the effects of micro focused ultrasound on facial rejuvenation. Methodology: This is an experimental study. The sample consisted of 30 volunteers, who were evaluated before treatment, 45 and 90 days after its beginning. A single application of the MFU was performed across the facial region. The parameters used were: 10 MHz cartridge with depth of 1.5 mm, 7 MHz with depth of 3 mm, and 4 MHz with focal depth of 4.5 mm;doses ranged from 0.1 to 2.0 J, according to the sensitivity of the volunteers treated, and the application time was of approximately 90 minutes. Clinical photographic analysis and facial symmetry analysis using Dolphin Imaging software were performed, and validated questionnaires. Two volunteers were submitted to blepharoplasty surgery, and one to rhytidoplasty surgery 45 days after the application of the MFU. Samples of the treated skin were taken after the surgical procedures and submitted to histological and immunohistochemical analyses. The volunteers answered a questionnaire to assess adverse reactions and satisfaction. Results: We observed a visible clinical improvement on the images by photography, and an improvement of facial symmetry in the measurements of the paralateronasal projection (p = 0.007), left lateral mandibular (p = 0.01), and right lateral mandibular (p = 0.008). The histological analysis showed an increase in the amount of fibroblasts (p = 0.02), blood vessels (p = 0.0062) and inflammatory cells (p = 0.0036), in addition to the production of type 1 collagen. In the immunohistochemical analysis, we observed the presence of the macrophage marker IHQ: CD68, indicating phagocytosis of adipose tissue and the presence of fibrosis. In the analysis of adverse reactions, only transient hyperemia was observed with t

关键词： Skin Aging Mechanical Waves Sagging Wrinkles

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Effects of Hydrolysed Collagen Associated or Not with Physical Agents on Tissue and Muscle Flaccidity—Firmez Method: Case Study

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Open Journal of Applied Sciences 2022年第1期12卷 82-98页

作者： Rafaella Rêgo Maia Patrícia Froes Meyer Rodrigo Marcel Valentim Da Silva Eneida De Morais Carreiro Thaynar Gonzaga Da Silva Lígia De Oliveira Revorêdo stephany Luanna queiroga Farias Ciro Dantas Soares Michelle Cordeiro Sanz Mariana Adélia Girotto Bussade José Dos Santos Bussade Mônica Etrusco Pedrosa Federal University of Rio Grande do Norte Natal Brazil University Centre of Rio Grande do Norte (UNIRN) Natal Brazil Estácio de Sá University Natal Brazil Potiguar University—UNP Natal Brazil Campinas State University (UNICAMP) Campinas Brazil Higher School of Sciences of Santa Casa de Misericórdia Vitória Brazil University of Säo Judas Tadeu S&#228o Paulo Brazil Federal University of Rio de Janeiro Rio de Janeiro Brazil University of Medical Sciences of Minas Gerais Minas Gerais Brazil

The combination of therapies may be the promising future for the treatment of esthetic alterations more efficiently and in less time, in order to obtain an excellent result. Our objective was to evaluate the effectiveness of hydrolysed collagen associated with radiofrequency and electrostimulation in the treatment of flaccidity in the abdominal and gluteal regions. The sample consisted of 6 women, evaluated through evaluation protocols, questionnaires, dynamometry, ultrasound exams, and histological analysis. The volunteers were distributed into three subgroups: hydrolysed collagen group (G-1), radiofrequency + hydrolysed collagen group (G-2) and radiofrequency + hydrolysed collagen + electrostimulation group (G-3). The ultrasound analysis of the abdominal muscles showed an increase in muscle thickness in all groups, but not significant (p > 0.05). The histological analysis showed an evident increase in type I collagen in groups G-2 and G-3, with proliferating cells (Ki67+). The results of dynamometry showed significant values in different times (p < 0.05). There was a significant result in the infraumbilical perimetry analysis, when compared between the groups with 30 days (p = 0.03) and with 60 days (p = 0.04). All participants rated the treatment positively. The use of combined therapies has shown superior results for the treatment of abdominal and gluteal flaccidity when compared with its isolated use, being the combination of therapies important in the treatment of flaccidity.

关键词： Sagging Collagen Radiofrequency Electro-Stimulation

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