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Health 2012年第12期4卷 1448-1456页

作者： Ian j.mes Martins Andrea. C. Wilson Wei Ling Florence Lim Simon. M. Laws stephanie. j. fuller Ralph Nigel Martins Centre of Excellence in Alzheimer’s Disease Research and Care School of Medical Sciences Edith Cowan University Perth Australia McCusker Alzheimer’s Research Foundation Hollywood Medical Centre Perth Australia School of Psychiatry and Clinical Neurosciences The University of Western Australia Perth Australia

Obesity, especially at mid-life, is a maj.r risk factor for atherosclerosis, insulin resistance and the metabolic syndrome, which in turn contribute to coronary artery disease (CAD), Type 2 diabetes and Alzheimer’s disease (AD). The rise in overweight and obesity in all societies is prompting intense research into the causes and effects of the condition. Obesity disrupts many body systems including glucose and lipid metabolism, circadian rhythms and liver function. It also causes or increases inflammation and oxidative stress. Within cells, the endoplasmic reticulum (ER) appears to be particularly susceptible to such metabolic disruption. Sirtuin 1?(Sirt1) and leptin have received attention recently as they are central regulatory factors for the body’s metabolic pathways which interact at particular levels, for example lipid and Abeta metabolism. This mini-review discusses recent findings concerning obesity, lipid metabolism and the role of Sirtuin 1 and how all influence the ER. A greater understanding of obesity and its effects on metabolic control systems of the body are required, to develop pharmacological, dietary and lifestyle changes that will reduce the incidence of CAD, Type 2 diabetes and AD.

关键词： Obesity Sirtuin 1 Alzheimer’s Disease Cardiovascular Disease Diabetes

Effect of Intensive Inorganic Fertilizer Application on Microbial Properties in a Paddy Soil of Subtropical China

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Agricultural Sciences in China 2011年第11期10卷 1758-1764页

作者： Klemens Ekschmitt stephanie.I j.Holzhauer Sabine Rauch j.stus Liebig University IFZ-Department of Animal EcologyH.-Buff-Ring 26-32D-35392 GiessenGermany

A field experiment with rice-rice rotation was conducted since 2002 in southeast China for investigating the response of soil microbial properties to intensive nitrogen fertilizer application. The tested soil was a subtropical paddy soil derived from Quaternary red clay. Differences between treatments existed in different application rates of urea when the experiment was designed. Urea was applied in five rates, i.e., 0, 0.5, 1, 1.5, and 2 U, equivalent to 0, 0.5, 1, 1.5, and 2 times the local average amount of urea application （900 kg urea ha-~ yr-~, equivalent to 414 kg N ha-1 yr-~）. In 2007, soil total nitrogen, available nitrogen, and soil organic carbon contents were increased by 10.2-27.9, 8.0-16.0, and 10.2-30.6%, respectively, in treatments with urea application rates of 0.5 to 2 U compared to control （0 U）. Microbial biomass carbon and nitrogen were also increased by 3.1-30.8 and 1.3-13.9%, respectively, in treatments with urea application. Basal respiration in treatments with urea input were 9.4-29.1% higher than that in control. However, changes of bacterial functional diversity had different trends. Urea fertilization enhanced bacterial functional diversity until treatment of 1 U, but re-decreased it from treatment of 1.5 U. Principal components analysis indicated that there were intimate relationships among soil organic matter, nitrogen nutrient, microbial biomass, and respiration. Nevertheless, microbial diversity was related to soil moisture contents after urea application. We conclude here that the application of N fertilizer improved soil microbial biomass and respiratory activity. But, microbial diversity was reduced when excessive urea was applied in the tested paddy soil.

关键词： paddy soil intensive N application microbial properties microbial functional diversity red soil region

Examining the Satisfaction and Values of Domestic and International Marriages

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Psychology Research 2015年第12期5卷 701-707页

作者： stephanie.j. Thorson-Olesen Viterbo University LaCrosse USA

Testing semiochemicals from aphid, plant and conspecific： attraction of Harmonia axyridis

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Insect Science 2012年第3期19卷 372-382页

作者： Pascal D. Leroy Thomas Schillings j.lien Farmakidis stephanie.Heuskin Georges Lognay Francois j. Verheggen Yves Brostaux Eric Haubruge Frederic Francis Departments of Functional and Evolutionary Entomology Departments of Analytical Chemistry Departments of Applied Statistics Computer Science and Mathematics University of Liege Gembloux Agro-Bio Tech Gembloux Belgium

Harmonia axyridis Pallas （Coleoptera： Coccinellidae） is an invasive specie affecting the dynamics and composition of several guilds. Nowadays, no biological control method is available to reduce the populations of this harmful coccinellid. Attractants and semiochemicals seem to be the best alternative but only few studies have tested the impact of semiochemicals on this Asian lady beetle. In this work, through wind- tunnel experiments, semiochemicals from aphids （Z,E-nepetalactone, [E]-β-farnesene, a-pinene and β-pinene）, from coccinellids （[-]-β-earyophyllene） and from the nettle Urtica dioica L. were evaluated as potential attractants. The nettle volatile compounds （[Z]-3- hexenol and [E]-2-hexenal） were extracted using a Clevenger Apparatus and identified by headspace gas chromatography-mass spectroscopy. In the wind-tunnel experiments, the main components of the aphid alarm pheromone as well as a component of the aphid sexual pheromone strongly attracted both sexes of the Asian lady beetle while （-）-β- caryophyllene only attracted few individuals and had no impact on the males. The nettle extract as well as the （Z）-3-hexenol oriented both males and females to the odor source. The （E）-2-hexenal was shown to have no effect on females even if this green leaf volatile attracted males. Because Z,E-nepetalactone was identified as the most efficient attractant in the wind-tunnel experiments, this volatile was also tested in a potato field where H. axyridis has been showed to respond to this semiochemical. This study highlighted that Z,E-nepetalactone orientated the Asian lady beetle H. axyridis under natural condi- tions, indicating that this volatile compound could certainly help for an efficient biological control approach against this invasive specie.

关键词： aphids attractant Harmonia axyridis plant semiochemicals wind-tunnel

Analysis of drop deformation dynamics in turbulent flow

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Chinese j.urnal of Chemical Engineering 2016年第2期24卷 264-277页

作者： stephanie.Nachtigall Daniel Zedel Matthias Kraume Chair of Chemical and Process Engineering Technische Universitat Berlin

Drop breakage and coalescence influence the particle formation in liquid-liquid dispersions. In order to reduce the influencing factors of the whole dispersion process, single drops where coalescence processes can be neglected were analyzed in this work. Drops passing the turbulent vicinity of a single stirrer blade were investi- gated by high-speed imaging. In order to gain a statistically relevant amount of drops passing the area of interest and corresponding breakage events, at least 1600 droplets were considered for each parameter set of this work. A specially developed fully automatic image analysis based on Matlab was used for the evaluation of the resulting high amount of image data. This allowed the elimination of the time-consuming manual analysis and further- more, allowed the obj.ctive evaluation of the drops＇ behavior. Different deformation parameters were consid- ered in order to describe the drop deformation dynamics properly. Regarding the ratio of both main particle axes （0axes）, which was therefore approximated through an ellipse, allowed the determination of very small de- viations from the spherical shape. The perimeter of the particle （0peri） was used for the description of highly de- formed shapes. In this work the results of a higher viscosity paraffin oil （ηd =127 mPa. s） and a low viscosity solvent （petroleum, ηd = 1.7 mPa-s） are presented with and without the addition of SDS to the continuous water phase. All results show that the experimentally determined oscillation but also deformation times underlie a wide spreading. Drop deformations significantly increased not only with increasing droplet viscosity, but also with decreasing interfacial tension. Highly deformed particles of one droplet species were more likely to break than more or less spherical particles. As droplet fragmentation results from a variety of different macro-scale de- formed particles, it is not assumed that a critical deformation value must be reached for the fragmentati

关键词： Drop deformation Drop breakage Liquid-liquid system Turbulent mixing Image analysis High-speed imaging

EVER GREEN:A POST-OCCUPANCY BUILDING PERFORMANCE ANALYSIS OF LEED CERTIFIED HOMES IN NEW ENGLAND

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j.urnal of Green Building 2011年第4期6卷 138-145页

作者： Sandy j.Beauregard stephanie.Berkland Simi Hoque Department of Environmental Conservation University of Massachusetts Amherst

The purpose of this research was to conduct a pilot study of LEED certified homes in New England one to five years after occupancy to determine whether they continue to perform at the level predicted during the certification *** criteria were defined to assess the performance of each home:(1)energy consumption for heating,cooling,lighting,electronics and appliances;(2)building envelope and air infiltration;(3)operations and maintenance;and(4)occupant satisfaction and indoor air *** qualitative and quantitative methods including blower door and duct blaster tests,utility bill analysis,and an occupant satisfaction survey were used to measure the post-occupancy performance of seven LEED certified homes in New *** were found between the original building performance as determined at the time of certification and the current level of building *** this is limited,initial research,these findings indicate a need for further post-occupancy research that can provide feedback to green certification programs,allowing them to be modified as necessary to better reflect the actual environmental impacts of certified buildings.

关键词： post-occupancy LEED residential certified homes home performance energy consumption

Getting in phase: DNA damage repair mechanisms and liquid-liquid phase separation of the plant-specific histone methyltransferase MtSUVR2

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Molecular Plant 2022年第8期15卷 1266-1267页

作者： stephanie.Hutin Chloe Zubieta Laboratoire de Physiologie Cellulaire et Végétale Univ.Grenoble AlpesCNRSCEAINRAEIRIG-DBSCI-LPCV17 Avenue des Martyrs38054 GrenobleFrance

Liquid-liquid phase separation(LLPS)has become a widely accepted mechanism forthedynamic compartmentalization of different cellular components into membraneless organelles or other cellular *** occurs when the concentration of a protein,nucleic acid,or other molecule reaches a saturation concentration and its partition into high-and low-concentration phases is energetically favorable.

关键词： separation liquid phase

Honeydew volatile emission acts as a kairomonal message for the Asian lady beetle Harmonia axyridis （Coleoptera： Coccinellidae）

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Insect Science 2012年第4期19卷 498-506页

作者： Pascal D. Leroy stephanie.Heuskin Ahmed Sabri Fran( ois j. Verheggen j.lien Farmakidis Georges Lognay Philippe Thonart j.an-Paul Wathelet Yves Brostaux Eric Haubruge Departments of Functional and Evolutionary Entomology Departments of Analytical Chemistry University of Liege Gembloux Agro-BioTech Walloon Center of Industrial Biology University of Liege B40 4000 Sart-Tilman Departments of General and Organic Chemistry Departments of Appfied Statistics Computer Science and Mathematics University of Liege Gembloux Agro-Bio Tech Gembloux Belgium

The Asian lady beetle Harmonia axyridis Pallas is considered as an invasive species in most territories where it has been introduced. Because aphid honeydew acts as an attraetant for many aphid predators and parasitoids, the obj.ctives of this work were to collect and identify the volatile compounds released from the aphid excretory product to evaluate how these semiochemicals could affect the H. axyridis foraging behavior. Twelve volatile chemicals were identified from the Megoura viciae Buckton honeydew including four alcohols, three ketones, three aldehydes, a pyrazine and a monoterpene. The volatiles 3-methyl-l-butanol and 3-methyl-butanal were highlighted as the two most abundant semiochemicals released from the M. viciae honeydew. Vieia faba L. plants treated with crude honeydew attracted more than 80% of the tested individuals with 40% of attracted beetles located on the plant. Four volatile compounds （3-hydroxy-2-butanone, 3-methyl-butanal, 3-methyl-1-butanol and limonene） were also highlighted to attract more than 75% of the coccinellids toward the odor source and to locate about 35% of them on the plants. Limonene was the most efficient attractant since 89% of the H. axyridis responded to this odor. The use of the identified semiochemicals as well as the composition of an artificial honeydew could certainly be helpful to control the dispersal of the Asian lady beetle H. axyridis.

关键词： aphid honeydew attractant Harmonia axyridis kairomone semiochemicals

Geochemistry of fine-grained sediments of the upper Cretaceous to Paleogene Gosau Group(Austria,Slovakia):Implications for paleoenvironmental and provenance studies

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Geoscience Frontiers 2013年第4期4卷 449-468页

作者： Gerald Hofer Michael Wagreich stephanie.Neuhuber Department of Geodynamics and Sedimentology.University of Vienna

Bulk rock geochemistry of 169 fine-grained sediment samples of the upper Cretaceous to Paleogene Gosau Group （Northern Calcareous Alps, Austria and Slovakia） fiom borehole and outcrop localities was performed to separate non-marine and marine deposits. Geochemical characteristics of different Gosau depositional systems, basins and sediment provenance using maj.r-, trace-, and rare earth elements were also investigated. Geochemical proxies such as boron concentrations were tested for seeking the possibilities of paleosalinity indicators. Due to the [act that several pelagic sections are represented by extremely low boron contents, B/AI＊ ratios are recognized as more robust and differentiate reliably between marine （mean： 160 ± 34） and non-marine （mean： 133 ± 33） samples. Using statistical factor analysis, hemipelagic to pelagic samples flom the Gieghi_ibl Syncline and Slovakian equivalents can be differentiated from marginal-marine to non-marine samples from the Grtinbach and Glinzendorf Syncline related to terrigenous （SiO2, AI203, K20, Th, Rb, Zr and others） and pelagic indicative elements （CaO, St, TOT/C and B/AI＊）. A clear indication for ophiolitic provenance is traced by high amounts of chromium and nickel. Only non-marine successions of the Glinzendorf Syncline show higher Cr and Ni concentrations （up to 250 and 400 ppm, respectively） and enriched Cr/V and Y/Ni ratios trending to an ultramafic source.

关键词： Gosau GroupGeochemistryPre-Neogene Vienna BasinBoronFactor analysisProvenance

Capturing, protecting and restoring plant diversity in the UK: RBG Kew and the Millennium Seed Bank

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Plant Diversity 2019年第2期41卷 124-131页

作者： Ted Chapman stephanie.Miles Clare Trivedi Royal Botanic Gardens Kew

Ex situ seed banking is a practical and cost-effective means of preserving wild plant diversity and a crucial complement to the in situ conservation and restoration of species and habitats. As pressures on the natural environment have grown, so has the call for seed banks to provide scientifically-robust,practical solutions to seed-related problems in nature conservation, from single-species recovery and reintroduction to the restoration of complex, dynamic communities at the largest scales. In this paper, we discuss how the Royal Botanic Gardens, Kew and its Millennium Seed Bank have responded to this call in the United Kingdom. We demonstrate that banked seed collections can provide a range of otherwiseunavailable, high quality, known-origin, genetically-diverse biological materials. The data, expertise and specialist facilities that accompany these collections are also valuable, helping overcome constraints to the collection, production and effective use of native seed. Challenges remain-to ensure ex situ collections protect the species and genetic diversity that will enable plants to adapt to a changing environment, and to find new ways for seed banks to mobilise their resources at a landscape scale.

关键词： Seed banking Ex situ conservation Botanic garden Species-reintroduction Ecological restoration Native seed production