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Capturing, protecting and restoring plant diversity in the UK: RBG Kew and the Millennium Seed Bank

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Plant Diversity 2019年第2期41卷 124-131页

作者： Ted Chapman stephanie Miles Clare Trivedi Royal Botanic Gardens Kew

Ex situ seed banking is a practical and cost-effective means of preserving wild plant diversity and a crucial complement to the in situ conservation and restoration of species and habitats. As pressures on the natural environment have grown, so has the call for seed banks to provide scientifically-robust,practical solutions to seed-related problems in nature conservation, from single-species recovery and reintroduction to the restoration of complex, dynamic communities at the largest scales. In this paper, we discuss how the Royal Botanic Gardens, Kew and its Millennium Seed Bank have responded to this call in the United Kingdom. We demonstrate that banked seed collections can provide a range of otherwiseunavailable, high quality, known-origin, genetically-diverse biological materials. The data, expertise and specialist facilities that accompany these collections are also valuable, helping overcome constraints to the collection, production and effective use of native seed. Challenges remain-to ensure ex situ collections protect the species and genetic diversity that will enable plants to adapt to a changing environment, and to find new ways for seed banks to mobilise their resources at a landscape scale.

关键词： Seed banking Ex situ conservation Botanic garden Species-reintroduction Ecological restoration Native seed production

Live-Cell Imaging of Dual-Labeled Golgi Stacks in Tobacco BY-2 Cells Reveals Similar Behaviors for Different Cisternae during Movement and Brefeldin A Treatment

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Molecular Plant 2011年第5期4卷 896-908页

作者： stephanie L. Madison Andreas Nebenfuhr Department of Biochemistry and Cellular and Molecular Biology University of Tennessee Knoxville TN 37996-0840 USA

In plant cells, the Golgi apparatus consists of numerous stacks that, in turn, are composed of several flattened cisternae with a clear cis-to-trans polarity. During normal functioning within living cells, this unusual organelle displays a wide range of dynamic behaviors such as whole stack motility, constant membrane flux through the cisternae, and Golgi enzyme recycling through the ER. In order to further investigate various aspects of Golgi stack dynamics and integrity, we co-expressed pairs of established Golgi markers in tobacco BY-2 cells to distinguish sub-compartments of the Golgi during monensin treatments, movement, and brefeldin A （BFA）-induced disassembly. A combination of cis and trans markers revealed that Golgi stacks remain intact as they move through the cytoplasm. The Golgi stack orientation during these movements showed a slight preference for the cis side moving ahead, but trans cisternae were also found at the leading edge. During BFA treatments, the different sub-compartments of about half of the observed stacks fused with the ER sequentially; however, no consistent order could be detected. In contrast, the ionophore monensin resulted in swelling of trans cisternae while medial and particularly cis cisternae were mostly unaffected. Our results thus demonstrate a re- markable equivalence of the different cisternae with respect to movement and BFA-induced fusion with the ER. In addi- tion, we propose that a combination of dual-label fluorescence microscopy and drug treatments can provide a simple alternative approach to the determination of protein localization to specific Golgi sub-compartments.

关键词： Golgi apparatus Golgi stack integrity brefeldin A monensin tobacco BY-2 cells live-cell imaging.

Impact of Business Practices on Individual Energy Consumption

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Journal of Electronic Science and Technology 2015年第4期13卷 349-354页

作者： Stephane Egger Mario Gstrein stephanie Teufel International Institute of Management in Technology University of Fribourg

Changing behaviours and attitudes towards more sustainable individual energy consum- ption is a difficult topic to address. After identifying the most recurrent factors influencing bad energy consum- ption-society＇s environmental short- sightedness, a lack of individual responsibility and a tendency to put responsibility upon firms, institutions, and governments, the authors evaluated the effect business practices can have on individual behaviour. By qualifying as highly credible sources of information, positioning themselves as examples to follow and providing its employees with the necessary smart, innovative technology, business communities can have a major impact on changing individual behaviours towards more sustainable energy consumption.

关键词： Business practices individualbehaviour sustainable energy consumption.

Increased working voltage of hexamine-coated porous carbon for supercapacitors

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Science Bulletin 2015年第18期60卷 1587-1597页

作者： stephanie L.Candelaria Guozhong Cao Department of Materials Science and Engineering University of Washington

Highly porous carbon, both unmodified and hexamine-coated on the pore surfaces, is tested at high working voltages in organic electrolyte for supercapacitors in order to enhance the energy density and power ***–gel processing allows for excellent control of the porous structure and chemical composition of carbon,resulting in a material with high surface area and a low level of impurities. This porous carbon can be modified using a simple solution-based method to enhance capacitance. Increasing the working voltage from 2.0 to 3.0 V significantly improves performance for both unmodified and hexamine-coated carbon. The energy density and power density increase at higher working voltage, and under certain conditions, the capacitance increases as *** stability is also investigated, with hexamine-coated carbon retaining more of its initial capacitance than unmodified carbon at all working voltages.

关键词： Supercapacitor High voltage Porouscarbon Hexamine Surface modification Nitrogen

Sensuous Past: Historical Imagination and Transmedia Aesthetics in Modern China

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Frontiers of Literary Studies in China-Selected Publications from Chinese Universities 2019年第3期13卷 440-474页

作者： stephanie SU Department of Art and Art History University of Colorado BoulderBoulderCO 80309USA

This paper examines the visual representation of the famous poem The Song of Everlasting Sorrow in modern *** by Li Yishi in 1929,this sequential set of paintings was based on the Tang poet Bai Juyi's poem,written under the same *** shown at the National Art Exhibition in Shanghai and then published as an illustrated book in 1932,Li's work rekindled public imagination of the tragic ***'s choice of subject,format,as well as style and its mixed reviews raise crucial questions regarding the notion of realism and the authenticity of historical *** paper argues that Li's work revealed new transmedia aesthetics and cross-cultural fascination with China's past that shaped the cultural identity of East Asia in the early twentieth century.

关键词： Li Yishi The Song of Everlasting Sorrow Yang Guifei historical representation transmedia aesthetics realism sensory experiences

Glaucoma-like damage induced by S100B injection is accompanied by microglial response

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Neural Regeneration Research 2022年第3期17卷 572-574页

作者： Teresa Tsai stephanie C.Joachim Experimental Eye Research Institute University Eye HospitalRuhr-University BochumBochumGermany

Glaucoma is currently the second leading cause of blindness *** to aging societies the number of patients suffering from this disease will further increase in the next ***,glaucoma can remain asymptomatic until it is rather far progressed,hence about 10–50% of patients are unaware they suffer from this *** is a progressive optic neuropathy associated with changes at the optic nerve head.

关键词： S100B injection damage

Pharmacogenomics of EGFR-targeted therapies in non-small cell lung cancer:EGFR and beyond

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Chinese Journal of Cancer 2015年第4期34卷 149-160页

作者： Christopher Delaney Samuel Frank R stephanie Huang Biological Sciences Division University of Chicago Department of Medicine University of Chicago The Affiliated Hospital School of MedicineNingbo University

Commonly observed aberrations in epidermal growth factor receptor(EGFR) signaling have led to the development of EGFR-targeted therapies for various cancers,including non-small cell lung cancer(NSCLC).EGFR mutations and overexpression have further been shown to modulate sensitivity to these EGFR-targeted therapies in NSCLC and several other types of ***,it is clear that mutations and/or genetic variations in EGFR alone cannot explain all of the variability in the responses of patients with NSCLC to EGFR-targeted *** instance,in addition to EGFR genotype,genetic variations in other members of the signaling pathway downstream of EGFR or variations in parallel receptor tyrosine kinase(RTK) pathways are now recognized to have a significant impact on the efficacy of certain EGFR-targeted *** this review,we highlight the mutations and genetic variations in such genes downstream of EGFR and in parallel RTK ***,the directional effects of these pharmacogenetic factors are discussed with a focus on two commonly prescribed EGFR inhibitors:cetuximab and *** results of this comprehensive review can be used to optimize the treatment of NSCLC with EGFR ***,they may provide the rationale for the design of subsequent combination therapies that involve the inhibition of EGFR.

关键词：表皮生长因子受体非小细胞肺癌药物基因组学 EGFR 靶向治疗信号传导途径受体酪氨酸激酶遗传变异

Multifunctional resonant wavefront-shaping meta-optics based on multilayer and multi-perturbation nonlocal metasurfaces

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Light(Science & Applications) 2022年第9期11卷 2194-2206页

作者： stephanie CMALEK ADAM COVERVIG ANDREA ALÙ NANFANG YU Department of Applied Physics and Applied Mathematics Columbia UniversityNew YorkNY 10027USA Photonics Initiative Advanced Science Research CenterCity University of New YorkNew YorkNY 10031USA Physics Program Graduate CenterCity University of New YorkNew YorkNY 10016USA

Photonic devices rarely provide both elaborate spatial control and sharp spectral control over an incoming *** optical metasurfaces,for example,the localized modes of individual meta-units govern the wavefront shape over a broad bandwidth,while nonlocal lattice modes extended over many unit cells support high quality-factor ***,we experimentally demonstrate nonlocal dielectric metasurfaces in the near-infrared that offer both spatial and spectral control of light,realizing metalenses focusing light exclusively over a narrowband resonance while leaving off-resonant frequencies *** devices attain this functionality by supporting a quasi-bound state in the continuum encoded with a spatially varying geometric *** leverage this capability to experimentally realize a versatile platform for multispectral wavefront shaping where a stack of metasurfaces,each supporting multiple independently controlled quasi-bound states in the continuum,molds the optical wavefront distinctively at multiple wavelengths and yet stay transparent over the rest of the *** a platform is scalable to the visible for applications in augmented reality and transparent displays.

关键词： spectrum resonant supporting

The history and development of the theory and practice of cybercartography

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International Journal of Digital Earth 2010年第1期3卷 2-15页

作者： D.R.Fraser Taylor stephanie Pyne Department of Geography and Environmental Studies Geomatics and Cartographic Research CentreCarleton UniversityOttawaONCanada

This paper describes the development of cybercartography since the introduction of the term in *** the origins of cybercartography were largely conceptual in nature,the evolution of cybercartography to date has been an iterative process reflecting the creative interplay between theory and practice.A major step forward was made in 2002 when the Geomatics and Cartographic Research Centre at Carleton University received a$2.5 million grant from the Social Sciences and Humanities Research Council of Canada to explore the utility of cybercartography to what was described as the New *** 2006,the interaction between theory and practice had led to considerable advances in cybercartography as a holistic,location-based concept and two new cybercartographic products,the Cybercartographic Atlas of Antarctica and the Cybercartographic Atlas of Canada’s Trade with the World,were *** 2006 and 2009,cybercartography was further developed as a result of interaction with indigenous communities,especially in Canada’s north and new interactive atlases such as the Kitikmeot Place Names Atlas and the Community Atlas of Arctic Bay were created in cooperation with the communities *** Nunaliit Cybercartographic Atlas Framework,built using open source software and open specifications and standards,was developed to facilitate direct input to these *** is now entering a new phase in both theory and practice building on a recently completed prototype atlas of Indigenous Perspectives and Knowledge.

关键词： cybercartography cybercartographic atlases indigenous mapping cybercartographic atlas framework iteration theory and practice