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Aluminum and Glyphosate Can Synergistically Induce Pineal Gland Pathology: Connection to Gut Dysbiosis and Neurological Disease

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Agricultural Sciences 2015年第1期6卷 42-70页

作者： stephanie seneff Nancy Swanson Chen Li Computer Science and Artificial Intelligence Laboratory MIT Cambridge MA USA Independent Researcher Abacus Enterprises Lummi Island WA USA

Many neurological diseases, including autism, depression, dementia, anxiety disorder and Parkinson’s disease, are associated with abnormal sleep patterns, which are directly linked to pineal gland dysfunction. The pineal gland is highly susceptible to environmental toxicants. Two pervasive substances in modern industrialized nations are aluminum and glyphosate, the active ingredient in the herbicide, Roundup?. In this paper, we show how these two toxicants work synergistically to induce neurological damage. Glyphosate disrupts gut bacteria, leading to an overgrowth of Clostridium difficile. Its toxic product, p-cresol, is linked to autism in both human and mouse models. p-Cresol enhances uptake of aluminum via transferrin. Anemia, a result of both aluminum disruption of heme and impaired heme synthesis by glyphosate, leads to hypoxia, which induces increased pineal gland transferrin synthesis. Premature birth is associated with hypoxic stress and with substantial increased risk to the subsequent development of autism, linking hypoxia to autism. Glyphosate chelates aluminum, allowing ingested aluminum to bypass the gut barrier. This leads to anemia-induced hypoxia, promoting neurotoxicity and damaging the pineal gland. Both glyphosate and aluminum disrupt cytochrome P450 enzymes, which are involved in melatonin metabolism. Furthermore, melatonin is derived from tryptophan, whose synthesis in plants and microbes is blocked by glyphosate. We also demonstrate a plausible role for vitamin D3 dysbiosis in impaired gut function and impaired serotonin synthesis. This paper proposes that impaired sulfate supply to the brain mediates the damage induced by the synergistic action of aluminum and glyphosate on the pineal gland and related midbrain nuclei.

关键词： Pineal Gland Aluminum Glyphosate Genetically Engineered Crops Autism Sulfate

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Death as a Drug Side Effect in FAERS: Is Glyphosate Contamination a Factor?

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Agricultural Sciences 2015年第12期6卷 1472-1501页

作者： stephanie seneff Nancy Swanson Chen Li Gerald Koenig Computer Science and Artificial Intelligence Laboratory MIT Cambridge MA USA Abacus Enterprises Lummi Island WA USA Health-e-Iron LLC Austin TX USA

An analysis of selected datasets from the FDA’s drug Adverse Event Reporting System (FAERS) leads us to hypothesize that glyphosate contamination in both food and drugs is a major contributor to chronic and acute kidney failure respectively. In chronic kidney failure, glyphosate-induced pancreatitis results in the release of trypsin, causing a leaky vasculature. The albumin-bound glyphosate escapes into the tissues, protecting the circulatory system and kidneys but resulting in multiple symptoms related to skin, gut, brain, bones, lungs, etc. The rare and poorly understood acute kidney failure response reported for protamine sulfate and Trasylol? is strikingly similar to that associated with glyphosate poisoning. Both drugs are derived from biological tissues that are plausibly contaminated with glyphosate. These drugs protect from haemorrhage, which leads to retention of glyphosate in the vasculature, are followed by circulatory collapse and a high likelihood of death as an outcome. We support our argument by comparing symptom profiles of selected subsets of FAERS with those related to glyphosate poisoning, anomalous reactions to protamine sulfate, and conditions showing strong statistical time-trend correlations with glyphosate.

关键词： Drug Side Effects Drug Contamination Renal Failure Glyphosate Pancreatitis Osteonecrosis Protamine Sulfate Aprotinin Oedema

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Guest Editorial Special Section on Energy-Efficient Technologies——Crowd Energy Applications

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Journal of Electronic Science and Technology 2019年第4期17卷 289-290页

作者： stephanie Teufel University of Fribourg

Digitization is the decisive driver of change in the energy *** and related models,such as crowd energy models,are the obvious effects that have already arrived in ***,research goes on,be it on new hardware units for contactless power transfer,models,and implementations for the use of different kinds of renewable energy in smart environments,especially on the use of storage technologies and the coupling of different areas(***-to-grid(V2G)or building-to-grid)and,most importantly,different sectors.

关键词： hardware smart environments

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Guest Editorial Special Section on Energy-Efficient Technologies--Crowd Energy Applications

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Journal of Electronic Science and Technology 2016年第4期14卷 289-290页

作者： stephanie Teufel University of Fribourg Switzerland

Since decades, the global electricity demand shows only one direction： a considerable constant increase every year. But the unlimited growth in energy consumption is discussed increasingly critical, not only primarily in terms of limitations but also in terms of more efficient, more intelligent, and more sustainable usage of energy. Energy-efficient technologies （EET） and renewable energy technologies are already in a competitive position in different markets, and they are also actively embedded in scientific research. Meanwhile,

关键词： EET Crowd Energy Applications Guest Editorial Special Section on Energy-Efficient Technologies view

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Guest Editorial：Special Issue on Energy-Efficient Technologies--Crowd Energy Applications

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Journal of Electronic Science and Technology 2018年第1期16卷 289-290页

作者： stephanie Teufel University of Fribourg Switzerland

The disruption of digital technologies has been a reality in many different industrial sectors for many *** digital transformation is now having an increasing impact on the energy sector as well as the so-called"smart... 详细信息

关键词： Crowd Energy Applications Guest Editorial:Special Issue on Energy-Efficient Technologies EET

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Prosumer Cooperation Behavior:Implications for Prosumer Community Design

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Journal of Electronic Science and Technology 2016年第4期14卷 298-310页

作者： Yves Hertig stephanie Teufel International Institute of Management in Technology University of Fribourg1700 FribourgSwitzerland

The decentralization of the energy sector＇s infrastructure is commonly understood as an important step towards an efficient and sustainable energy system. However, technical measures only have a limited impact on the systems goals. The decentralization of decision-making, the empowerment of households and the occurrence of prosumer communities require more human-centric approaches to meet future challenges; the application of the subsidiarity principle and decentralization seems inevitable but also unclear in its implementation in an energy system, the cooperation behavior of community members gains in importance and the design of prosumer communities must overcome economic problems. This article emphasizes the human-centered challenges which go along with prosumer communities. We apply economic principles to reveal major problems which go with the shifts in energy-related decision-making towards prosumers and integrate behavioral science for prosumer community design. We highlight the importance of energy as an interpersonal construct; a view on energy which will gain in importance within a prosumer communities shaped network.

关键词： Cooperation Behavior Crowd Energy,Energy Economics Energy Prosumer ProsumerCommunity Design.

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NUMERICAL RECONSTRUCTION OF SMALL PERTURBATIONS IN THE ELECTROMAGNETIC COEFFICIENTS OF A DIELECTRIC MATERIAL

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Journal of Computational Mathematics 2014年第1期32卷 21-38页

作者： Marion Darbas stephanie Lohrengel LAMFA UMR CNRS 7252 - Universitd de Picardie Jules Verne Amiens France LMR EA 4535 - Universitd de Reims Champagne-Ardenne Reims France

The aim of this paper is to solve numerically the inverse problem of reconstructing small amplitude perturbations in the magnetic permeability of a dielectric material from partial or total dynamic boundary measurements. Our numerical algorithm is based on the resolution of the time-dependent Maxwell equations, an exact controllability method and Fourier inversion for localizing the perturbations. Two-dimensional numerical experiments illustrate the performance of the reconstruction method for different configurations even in the case of limited-view data.

关键词： Maxwell's equations Inverse problems Numerical reconstruction Exact boundary controllability Fourier inversion.

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Special Section on Energy-Efficient Technologies:Crowd Energy Applications

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Journal of Electronic Science and Technology 2015年第3期13卷 193-194页

作者： stephanie Teufel University of Wollongong the Carl von Ossietzky Universitat Oldenburg the International Institute of Management in Technology the Faculty of Economics and Social Sciences University of Fribourg

It is no secret--the world as it is today only runs with energy; and it is also no secret that the world is faced with steadily increasing energy demands. The reduction of dependence on fossil fuels is a global goal. To achieve this goal three paths have to be considered： First, the substitution of fossil fuels with renewable energy; secondly, the increase in energy efficiency and the expansion of opportunities for energy storage; and thirdly, to find solutions to the associated socio-economic challenges.

关键词： Special Section on Energy-Efficient Technologies

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Crowd Energy Management: New Paradigm for Electricity Market

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Journal of Electronic Science and Technology 2015年第3期13卷 195-205页

作者： Mario Gstrein stephanie Teufel the International Institute of Management in Technology University of Fribourg

The traditionally centralized approach of electricity networks is progressively undergoing a shift towards a decentralized, distributed structure. The local and crowd-based principle is transforming the existing supply chain and related activities into a value network （VN）. Previous researches on crowd value network concepts focus on the activities of infrastructure and load management and neglect activities that generate collaboration. Collaboration with and within crowds particularly demands a different mindset and management of sharing values, information, benefit, and risks. Furthermore, these concepts must integrate technical, processual, and social aspects. Thus, this article proposes a holistic framework of electricity VN management for crowd energy. It redefines VN activities for infrastructure and load management while appending VN activities for social electricity handling. Additionally, the framework illustrates the interactions among these three elements and concludes with an adaption cycle for the crowd value network.

关键词： Crowd distribution systems value electricity management. energy decentralized network collaboration,

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Mental health facility codesign: A new research method for integrating the service user voice in design processes using virtual reality

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General Psychiatry 2019年第3期32卷 146-151页

作者： stephanie Liddicoat School of Design Faculty of Health Arts and Design Swinburne University of Techn ology Melbourne Victoria Australia Faculty of Architecture Building and Planning The University of Melbourne Melbourne Victoria Australia

Background Within healthcare environments, the emerging field of evidence-based design (EBD) explores the links between wellbeing and good design practice of the built environment. Aim By optimising both design processes and design outcomes, knowledge produced wrthin this field seeks to improve staff performance, augment patient healing and enhance service outcomes and experiences. Methods In a prior study by the author, a mental health service building design was developed which integrated feedback from mental health service users relative to what aspects of the built environments of their care would enhance their service outcomes and experiences, encourage them to avail themselves of services and/or engage in therapy, and those that would reduce their willingness to avail themselves of services. Results The research project protocol detailed here is the final testing stage of this body of work, where service users are invited to evaluate the final building design, experienced through virtual reality. This study addresses a gap in the literature, and aims to advance the field of EBD, and codesign with mental health service users, using virtual reality. Conclusions This research method details the aims, study design, methods and limitations of the study, with recommendations for future researchers.

关键词： Mental health facility codesign virtual reality

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