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Colonic gas explosion during therapeutic colonoscopy with electrocautery

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World Journal of Gastroenterology 2007年第40期13卷 5295-5298页

作者： spiros d.ladas George Karamanolis Emmanuel Ben-Soussan Hepatogastroenterology Unit 2~(nd) Department of Internal Medicine-PropaedeuticMedical SchoolAthens University"Attikon"University General HospitalAthensGreece Clinique de I'Alma 166 rue de I'université 750007ParisFrance

Therapeutic colonoscopy with electrocautery is widely used around the world. Adequate colonic cleansing is considered a crucial factor for the safety of this procedure. Colonic gas explosion, although rare, is one of the most frightening iatrogenic complications during colonoscopy with electrocautery. This complication is the result of an accumulation of colonic gases to explosive concentrations, but may be prevented by meticulous bowel preparation. The purpose *** review is to discuss the indications and the types of bowel preparations for therapeutic colonoscopy, and to contribute recommendations for the adequate bowel preparation for colonoscopy with electrocautery.

关键词： Colonic gas explosion Electrocautery Therapeutic polypectomy Argon plasma coagulation Polypectomy

Early ileocolonoscopy with biopsy for the evaluation of persistent post-transplantation diarrhea

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World Journal of Gastroenterology 2010年第30期16卷 3834-3840页

作者： Giorgos Bamias John Boletis Theodoros Argyropoulos Chrysanthi Skalioti Spyros I Siakavellas Ioanna delladetsima Irene Zouboulis-Vafiadis George L daikos spiros d.ladas Gastroenterology division 1st Department of Internal MedicinePropaedeuticMedical SchoolUniversity of Athens"Laikon" Hospital11527AthensGreece department of Nephrology and Renal Transplantation Unit "Laikon" Hospital11527AthensGreece 1st department of Pathology University of Athens"Laikon"Hospital11527AthensGreece

AIM: To investigate the signifi cance of ileocolonoscopy with histology in the evaluation of post-transplantation persistent diarrhea (Pd). METHOdS: We retrospectively reviewed all records of renal transplant patients with Pd, over a 3-year period. All patients were referred for ileocolonoscopy with biopsy, following a negative initial diagnostic work up. Clinical and epidemiological data were compared between cases with infectious or drug-induced diarrhea. RESULTS: We identif ied 30 episodes of Pd in 23 renaltransplant patients (1-3 cases per patient). There were 16 male patients and the mean age at the time of Pd was 51.4 years. The average time from transplantation to a Pd episode was 62.3 ± 53.2 mo (range 1-199 mo). Ileocolonoscopy detected mucosal abnormalities in 19 cases, whereas the intestinal mucosa appeared normal in 11 cases. Histological examination achieved a specific diagnosis in 19/30 cases (63.3%). In nine out of 11 cases (82%) with normal endoscopic appearance of the mucosa, histological examination of blinded biopsies provided a specif ic diagnosis. The etiology of Pd was infectious in 11 cases (36.6%), drug-related in 10 (33.3%), of other causes in three (10%), and of unknown origin in six cases (20%). Infectious diarrhea occurred in significantly longer intervals from transplantation compared to drug-related Pd (85.5 ± 47.6 mo vs 40.5 ± 44.8 mo, P dingly, Pd due to drug-toxicity was rarely seen after the f irst year post-transplantation. Clinical improvement followed therapeutic intervention in 90% of cases. Modif ication of immunosuppressive regimen was avoided in 57% of patients. CONCLUSION: Early ileocolonoscopy with biopsies from both affected and normal mucosa is an important adjunctive tool for the etiological diagnosis of Pd in renal transplant patients.

关键词： Endoscopy Post-transplantation diarrhea Histology Enteric infections Mycophenolate mofetilcolitis

Two cameras detect more lesions in the small-bowel than one

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World Journal of Gastroenterology 2011年第11期17卷 1462-1467页

作者： Konstantinos Triantafyllou Ioannis S Papanikolaou Kostis Papaxoinis spiros d.ladas Hepatogastroenterology Unit 2nd Department of Internal Medicine-PropaedeuticAttikon University General HospitalMedical SchoolAthens University12464 AthensGreece 1st department of Internal Medicine-Propaedeutic Laiko General HospitalMedical SchoolAthens University11527 AthensGreece

AIM:To explore the feasibility of dual camera capsule (dCC)small-bowel(SB)imaging and to examine if two cameras complement each other to detect more SB ***:Forty-one eligible,consecutive patients underwent dCC SB *** experienced investigators examined the videos and compared the total number of detected lesions to the number of lesions detected by each camera *** tolerability was assessed using a ***:One patient was *** cameras detected 68 positive findings(POS)in 20(50%)*** of them were detected by the"yellow"camera,48 by the"green"and 28 by both cameras;44%(n=22)of the"yellow"camera’s POS were not detected by the"green"camera and 42%(n=20)of the"green" camera’s POS were not detected by the"yellow"*** two cases,only one camera detected significant *** participants had 216 findings of unknown significance(FUS).The"yellow","green"and both cameras detected 171,161,and 116 FUS,respectively;32%(n=55)of the"yellow"camera’s FUS were not detected by the"green"camera and 28%(n=45)of the"green"camera’s FUS were not detected by the "yellow"*** were no complications related to the examination,and 97.6%of the patients would repeat the examination,if ***:dCC SB examination is feasible and well *** two cameras complement each other to detect more SB lesions.

关键词： Small-bowel capsule endoscopy dual camera capsule endoscope Feasibility Lesion detection diagnostic yield

Omeprazole maintenance therapy prevents recurrent ulcer bleeding after surgery for duodenal ulcer

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World Journal of Gastroenterology 2006年第5期12卷 791-795页

作者： Konstantinos demertzis dimitrios Polymeros Theodoros Emmanuel Konstantinos Triantafyllou Pericles Tassios spiros d.ladas Hepatogastroenterology Unit2~(nd) Department of Internal Medicine"Attikon"University General Hospital11528 AthensGreece

AIM： To evaluate the omeprazole maintenance therapy in patients with recurrent ulcer bleeding after surgery for duodenal ulcer. METHOdS： We studied 15 consecutive patients with recurrent ulcer bleeding after surgery for duodenal ulcer. Omeprazole （20 mg/d） maintenance therapy was given after ulcer healing. In addition to clinical follow-up, ambulatory 24-h gastric pH assay was performed before and during omeprazole therapy in those patients and controls with previous duodenal ulcer surgery but no ulcer recurrence. RESULTS： All the 15 ulcers were healed after being treated with omeprazole （40 mg/d） for 2 too. Eleven patients with two （1-9） episodes of recurrent ulcer bleeding completed the follow-up （43, 12-72 too）. None of them had a bleeding episode while on omeprazole. One patient discontinued the therapy and had recurrent bleeding. The median 24-h fraction time of gastric pH 〈4 in patients was 80, 46-95%, and was reduced to 32, 13-70% by omeprazole （P= 0.002）. CONCLUSION： Long-term maintenance therapy with omeprazole （20 rag/day） is effective in preventing recurrent ulcer bleeding.

关键词： duodenal ulcer Gastrectomy Vagotomy Omeprazole

最小二乘谱及其在超导重力观测数据分析中的应用

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武汉大学学报（信息科学版） 2005年第7期30卷 613-616页

作者：尹晖 spiros d.Pagiatakis 武汉大学测绘学院武汉市珞喻路129号430079 约克大学地球与空间科学和工程系

运用投影理论和基于向量空间中最小二乘平差原理,介绍了最小二乘谱分析方法,给出了最小二乘谱的计算公式。利用加拿大超导重力观测数据实例,讨论了最小二乘谱分析的策略和步骤。

关键词：最小二乘谱超导重力仪数据分析

三裂叶野葛毛状根的诱导及其固体培养和液体培养

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生物工程学报 2003年第3期19卷 307-311页

作者：施和平权宏 spiros Kintzios 华南师范大学生命科学学院广州510631 Laboratory of Plant Physiology Department of Agricultural BiotechnologyAgricultural University of Athens

发根农杆菌 (Agrobacteriumrhizogenes)ATCC15 834感染三裂叶野葛 (Puerariaphaseoloides)叶片外植体 2 0d后产生毛状根 ,毛状根可直接从叶片外植体叶脉处或从叶脉处产生的愈伤组织上产生。感染 35d后 ,约 85 %的叶片外植体产生毛状根... 详细信息

发根农杆菌 (Agrobacteriumrhizogenes)ATCC15 834感染三裂叶野葛 (Puerariaphaseoloides)叶片外植体 2 0d后产生毛状根 ,毛状根可直接从叶片外植体叶脉处或从叶脉处产生的愈伤组织上产生。感染 35d后 ,约 85 %的叶片外植体产生毛状根。毛状根能在无外源生长调节剂的MS固体和液体培养基上自主生长。PCR扩增结果表明 ,发根农杆菌Ri质粒的rolB和rolC基因已在三裂叶野葛毛状根基因组中整合并得到表达。与固体培养的毛状根相比 ,在液体培养基中培养的毛状根不仅生长迅速 ,也不会形成愈伤组织。在无外源生长调节剂的液体MS培养基中培养 15d的三裂叶野葛毛状根的鲜重、干重、可溶性总糖含量及细胞内活性氧 (ROS)含量分别为固体培养毛状根的1.5 9倍、1.18倍、5 .2 5倍和 1.16倍。

关键词：发根农杆菌三裂叶野葛毛状根可溶性总糖固体培养液体培养活性氧植物细胞基因组

Classic clamp-and-tie total thyroidectomy for large goiters in the modern era:To drain or not to drain?

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World Journal of Otorhinolaryngology 2014年第1期4卷 1-5页

作者： Theodossis S Papavramidis Ioannis Pliakos Nick Michalopoulos George Mistriotis Niko Panteli George Gkoutzamanis spiros Papavramidis 3rd department of Surgery AHEPA University HospitalAristotle University of Thessaloniki54655 ThessalonikiGreece

AIM: To evaluate the role of drains in clamp-and-tie total thyroidectomy(c TT) for large goiters. METHOdS: A hundred patients were randomized into group d(drains maintained for 24 h) and Nd(no drains). We recorded epidemiological characteristics, thyroid pathology, hemostatic material, intraoperative events, operative time and difficulty, blood loss, biochemical and hematological data, postoperative vocal alteration and pain, discomfort, complications, blood in drains, and ***: The groups had comparable preoperative characteristics, pathology, intraoperative and postoperative data. Hemostatic material was used in all patients of group Nd. Forty patients in group d and 9 in Nd felt discomfort(P drains in c TT for large goiters give no advantage or disadvantage to the surgeon. The only "major disadvantage" is the discomfort for the patient. Inversely, drains probably influence surgeons' serenity,especially when c TT is performed in nonspecialized departments.

关键词： Total thyroidectomy drains Postoperative complications Postoperative hemorrhage discomfort