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Utilization of Nanomaterials as Anode Modifiers for Improving Microbial Fuel Cells Performance

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Journal of Renewable Materials 2020年第12期8卷 1581-1605页

作者： Nishit Savla Raksha Anand soumya pandit Ram Prasad Amity Institute of Biotechnology Amity UniversityMumbaiIndia Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida201306India Department of Botany Mahatma Gandhi Central UniversityBihar845401India

Microbial fuel cells(MFCs)are an attractive innovation at the nexus of energy and water security for the *** utilizes electrochemically active microorganisms to oxidize biodegradable substrates and generate bioelectricity in a single *** material of the anode plays a vital role in increasing the MFC’s power *** anode in MFC can be upgraded using nanomaterials providing benefits of exceptional physicochemical *** nanomaterials in anode gives a high surface area,improved electron transfer promotes electroactive *** power output in terms of Direct current(DC)can be obtained as the consequence of improved microbe-electrode ***,several limitations like complex synthesis and degeneration of property do exist in the development of nanomaterial-based *** present review discusses different renewable nanomaterial applied in the anode to recover bioelectricity in *** nanomaterials have emerged in the past decade as promising materials for anode con*** materials have also demonstrated the capacity to become potential anode materials of *** of a few transition metal oxides have been explored for efficient extracellular electron transport(EET)from microbes to the anode.

关键词： Microbial fuel cell(MFC) anodic modifications capacitance carbon nanotubes graphene porous carbons metallic nanomaterials power density coulombic efficiency

Epigenetic regulation−The guardian of cellular homeostasis and lineage commitment

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BIOCELL 2021年第3期45卷 501-515页

作者： KAVITHA GOVARTHANAN PIYUSH K UMAR GUPTA BINITA ZIPPORAHE REKHA GAHTORI soumya pandit RAM PRASAD Department of Biotechnology Indian Institute of Technology MadrasChennai600036India Department of Life Sciences Sharda UniversityGreater NoidaUttar Pradesh201310India Department of Biotechnology Campus–BhimtalKumaun UniversityNainitalUttarakhand263136India Department of Botany Mahatma Gandhi Central UniversityMotihariBihar845401India

Stem cells constitute the source of cells that replenishes the worn out or damaged cells in our tissue and enable the tissue to carry out the destined ***-specific stem cells are compartmentalized in a niche,which keeps the stem cells under quiescent ***,understanding the molecular events driving the successful differentiation of stem cells into several lineages is essential for its better manipulation of human *** the developmental aspects of the cell,the cellular function is greatly dependent on the epigenomics signature that in turn governs the expression profile of the *** stable inheritance of the epigenome is crucial for the development,modulation,and maintenance of the cell and its complex tissue-specific *** evidence suggesting that stem cell chromatin comprises a specialized state in which self-renewing genes and its downstream lineage-specific genes are kept paralleled poised for ***,the epigenetic regulatory network and pathway dictate lineage commitment and *** mainly modifies the chromatin landscape to facilitate euchromatin and heterochromatin architecture,which in turn alters the accessibility of transcription factors to the gene *** methylation and histone marks are the two widely studied epigenetic modifications regulating the transcriptome profile of a specific *** in the epigenetic landscape lead to diseases or ***,we emphasize the prominence of the epigenetic network and its regulation in normal tissue functioning and in the diseased ***,we highlighted the emerging role of epigenetic modifiers in lineage differentiation and epigenetic markers as novel druggable targets for cancer therapy.

关键词： Epigenetics Chromatin Genome Methylation Inheritance Modulation

A Comprehensive Review on Oxygen Reduction Reaction in Microbial Fuel Cells

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Journal of Renewable Materials 2022年第3期10卷 665-697页

作者： Pooja Dange Nishit Savla soumya pandit Rambabu Bobba Sokhee P.Jung Piyush Kumar Gupta Mohit Sahni Ram Prasad Amity Institute of Biotechnology Amity UniversityMumbai410206India Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida201306India Department of Physics Southern University and A&M CollegeBaton Rouge70813USA Department of Environment and Energy Engineering Chonnam National UniversityGwangju61186Korea Department of Physics School of Basic Sciences and ResearchSharda UniversityGreater Noida201306India Department of Botany Mahatma Gandhi Central UniversityBihar845401India

The focus of microbial fuel cell research in recent years has been on the development of materials,microbes,and transfer of charges in the system,resulting in a substantial improvement in current density and improved power *** cathode is generally recognized as the limiting factor due to its high-distance proton transfer,slow oxygen reduction reaction(ORR),and expensive *** heterogeneous reaction determines power gen-eration in *** comprehensive review describes-recent advancements in the development of cathode mate-rials and catalysts associated with *** recent studies indicated the utilization of different metal oxides,the ferrite-based catalyst to overcome this *** studies conclude that some cathode materials,in parti-cular,graphene-based conductive polymer composites with non-precious metal catalysts provide substantial ben-efits for sustainable development in the field of ***,it also highlights the potentiality to replace the conventional platinum air cathode for the large-scale production of the next generation of *** was evi-dent from the experiments that cathode catalyst needs to be blended with conductive carbon materials to make cathode conductive and efficient for *** review discusses various antifouling strategies for cathode biofoul-ing and its effect on the MFC ***,it also depicts cost estimations of various catalysts essential for further scale-up of MFC technology.

关键词： Cathode catalyst microbial fuel cell(MFC) nanomaterials oxygen reduction reaction(ORR) biofouling biocathode

Synthesis, Characterization and Remedial Action of Biogenic Silver Nanoparticles and Chitosan-Silver Nanoparticles against Bacterial Pathogens

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Journal of Renewable Materials 2022年第12期10卷 3093-3105页

作者： Piyush Kumar Gupta D.Karthik Kumar M.Thaveena soumya pandit Somya Sinha R.Ranjithkumar Walaa F.Alsanie Vijay Kumar Thakur Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida201310Uttar PradeshIndia Viyen Biotech LLP CoimbatoreTamil Nadu641031India Department of Biotechnology Kongunadu Arts and Science CollegeCoimbatoreTamil Nadu641029India Department of Biotechnology Graphic Era Deemed to be UniversityDehradunUttarakhand248002India Department of Clinical Laboratories Sciences The Faculty of Applied Medical SciencesTaif UniversityTaif21944Saudi Arabia Biorefining and Advanced Materials Research Center SRUCEdinburghEH93JGUK Department of Mechanical Engineering School of EngineeringShiv Nadar UniversityNoidaGreater Noida201314India School of Engineering University of Petroleum&Energy Studies(UPES)DehradunUttarakhand248007India

Custard apple is a dry land *** leaves exhibit different pharmacological *** the present study,both silver(Ag)nanoparticles and chitosan-coated Ag(Chi-Ag)nanoparticles were fabricated using the aqueous leaf extract of the custard apple *** preliminary phytochemical analysis,various types of phytocompounds were found in the aqueous leaf extract of the same ***,both nanoparticles were physiochemically *** analysis exhibited the fingerprint vibrational peaks of active bioactive compounds in plant extract,Ag nanoparticles,and Chi-Ag ***/Visible spectral analysis revealed the highest absorbance peak at 419 nm,indicating the presence of Ag *** analysis presented the face-centered cubic(FCC)structure of both prepared ***,the average crystalline size of both Ag nanoparticles and Chi-Ag nanoparticles was calculated to be 23 and 74 nm,*** analysis showed the spherical and cubical shapes of Ag nanoparticles and Chi-Ag nanoparticles,*** analysis indicated a peak around 3.29 keV,conforming to the binding energies of Ag *** biogenic nanomaterial also showed strong antibacterial activity against all tested bacterial pathogens.

关键词： Custard apple chitosan Ag nanoparticles Chi-Ag nanoparticles antibacterial

Biosurfactant-assisted phytoremediation of potentially toxic elements in soil:Green technology for meeting the United Nations Sustainable Development Goals

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Pedosphere 2022年第1期32卷 198-210页

作者： Songita SONOWAL Amy R.NAVA Sanket J.JOSHI Siddhartha Narayan BORAH Nazim F.ISLAM soumya pandit Ram PRASAD Hemen SARMA Department of Botany School of Life SciencesMahatma Gandhi Central UniversityMotihari 845401India Department of Molecular&Cellular Physiology Stanford UniversityStanfordCA 94305SA Oil&Gas Research Center Central Analytical and Applied Research UnitSultan Qaboos UniversityMuscat 123Oman Centre for the Environment Indian Institute of Technology GuwahatiGuwahati 781039India Institutional Biotech Hub(IBT Hub) Department of BotanyNanda Nath Saikia CollegeTitabar 785630India Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater Noida 201306India

Biosurfactants are biomolecules produced by microorganisms, low in toxicity, biodegradable, and relatively easy to synthesize using renewable waste substrates. Biosurfactants are of great importance with a wide and versatile range of applications, including the bioremediation of contaminated sites. Plants may accumulate soil potentially toxic elements(PTEs), and the accumulation efficacy may be further enhanced by the biosurfactants produced by rhizospheric microorganisms. Occasionally, the growth of bacteria slows down in adverse conditions, such as highly contaminated soils with PTEs. In this context,the plant's phytoextraction capacity could be improved by the addition of metal-tolerant bacteria that produce biosurfactants. Several sources, categories,and bioavailability of PTEs in soil are reported in this article, with the focus on the cost-effective and sustainable soil remediation technologies, where biosurfactants are used as a remediation method. How rhizobacterial biosurfactants can improve PTE recovery capabilities of plants is discussed, and the molecular mechanisms in bacterial genomes that support the production of important biosurfactants are listed. The status and cost of commercial biosurfactant production in the international market are also presented.

关键词： bacterial genome metal-tolerant bacteria phytoextraction technology plant growth-promoting rhizobacteria rhizospheric microorganism

Delineating the role of phytocompounds against anti-bacterial drug resistance–An update

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BIOCELL 2021年第6期45卷 1465-1477页

作者： REKHA GAHTORI MOSLEH MOHAMMAD ABOMUGHAID NIDHI NEGI SARAVANAN KRISHNAN SUGAPRIYA DHANASEKARAN soumya pandit KANU PRIYA DILLIP KUMAR BISHI RAM PRASAD PIYUSH KUMAR GUPTA Department of Biotechnology Sir J.C.Bose Technical CampusKumaun UniversityNainitalIndia Department of Medical Laboratory Sciences University of BishaBishaSaudi Arabia Department of Chemistry Kumaun UniversityNainitalIndia Dhanvantari Nano Ayushadi Pvt. Ltd.ChennaiIndia Department of Medical Laboratory Sciences(Pathology) College of Applied Medical SciencesPrince Sattam Bin Abdulaziz UniversityRiyadhSaudi Arabia Department of Life Sciences School of Basic Sciences and ResearchSharda UniversityGreater NoidaIndia Department of Biotechnology Rama Devi Women’s UniversityBhubaneswarIndia Department of Botany Mahatma Gandhi Central UniversityMotihariIndia

Antibacterial resistance developed by bacteria due to the unlimited use of antibiotics has posed a challenge for human *** kind of problem is not limited to India only,but it is a global ***,many treatments and medicines for bacterial diseases have been ***,they possess some ***,the alternative medicine has been used to target the drug resistant mechanisms and such medicines have less side effects which is becoming *** products have traditionally or historically been of importance for the development of antibacterial agents and are also known to overcome bacterial drug resistance by directly targeting the drug resistance mechanisms in *** recent years,researchers have also focused on new drug discovery from plant-based *** have looked on various phytocompounds as antibacterial *** the current review,we report various classes of secondary metabolites such as phenolic compounds,flavonoids,alkaloids,saponins,terpenes,quinones,and some essential oils that have been used as an antibacterial *** addition,we also discuss several mechanisms behind bacterial multi-drug resistance that are used during bacterial pathogenesis.

关键词： Drug-resistance Phytocompounds Antibacterial Mechanisms Medicinal plants Natural products

Hemostatic radiotherapy for bleeding gastrointestinal

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2261-2263页

作者： Vrushab Rao soumya Singh Bhooshan Zade Department of Cyberknife Radiosurgery and Radiation Oncology Ruby Hall ClinicPune 411001MaharashtraIndia

Hemostatic radiotherapy is a non-invasive treatment for bleeding gastrointestinal(GI)tumors,promoting tumor shrinkage,blood supply reduction,and fibrotic tissue *** is effective in cases where traditional interventions are insufficient or contraindicated and can prevent recurrent bleeding in patients with GI bleeding *** schedules are also effective for tumor control and patient compliance.

关键词： Gastrointestinal tumors Hemostatic radiotherapy Palliative radiotherapy Acute bleeding Hypofractionation

SARS-CoV2 Nsp3 protein triggers cell death and exacerbates amyloid β42-mediated neurodegeneration

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Neural Regeneration Research 2024年第6期19卷 1385-1392页

作者： Aditi Singh Anuradha Venkatakrishnan Chimata Prajakta Deshpande soumya Bajpai Anjali Sangeeth Mrigendra Rajput Amit Singh Department of Biology University of DaytonDaytonOHUSA Premedical Program University of DaytonDaytonOHUSA Center for Tissue Regeneration and Engineering at Dayton(TREND) University of DaytonDaytonOHUSA The Integrative Science and Engineering Center University of DaytonDaytonOHUSA Center for Genomic Advocacy(TCGA) Indiana State UniversityTerre HauteINUSA

Infection caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV2)virus,responsible for the coronavirus disease 2019(COVID-19)pandemic,induces symptoms including increased inflammatory response,severe acute respiratory syndrome(SARS),cognitive dysfunction like brain fog,and cardiovascular ***-term effects of SARS-CoV2 COVID-19 syndrome referred to as post-COVID-19 syndrome on age-related progressive neurodegenerative disorders such as Alzheimer's disease remain *** the targeted misexpression of individual SARS-CoV2 proteins in the retinal neurons of the Drosophila melanogaster eye,we found that misexpression of nonstructural protein 3(Nsp3),a papain-like protease,ablates the eye and generates dark necrotic *** misexpression of Nsp3 in the eye triggers reactive oxygen species production and leads to apoptosis as shown by cell death reporters,terminal deoxynucleotidyl transferase(TdT)dUTP Nick-end labeling(TUNEL)assay,and dihydroethidium ***,Nsp3 misexpression activates both apoptosis and autophagy mechanism(s)to regulate tissue *** expression of SARS-CoV2 Nsp3 in murine neuroblastoma,Neuro-2a cells,significantly reduced the metabolic activity of these cells and triggers cell *** of SARS-CoV2 Nsp3 in an Alzheimer's disease transgenic fly eye model(glass multiple repeats[GMR]>amyloidβ42)further enhances the neurodegenerative rough eye phenotype due to increased cell *** findings suggest that SARS-CoV2 utilizes Nsp3 protein to potentiate cell death response in a neurodegenerative disease background that has high pre-existing levels of neuroinflammation and cell death.

关键词： Alzheimer's disease apoptosis autophagy COVID-19 Drosophila necrosis Neuro-2a cells neurodegeneration post COVID-19 syndrome SARS-CoV2

Exploring commercial water electrolyser systems:a data-based analysis of product characteristics

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Clean Energy 2024年第1期8卷 126-133页

作者： Xin Jin Shi You Marianne Petersen Jonathan Riofrio soumya Thakur Chresten Træholt Zhijian Feng Department of Wind and Energy Systems Technical University of Denmark2800 Kgs.LyngbyDenmark Siemens Gamesa Renewable Energy A/S 7330 BrandeDenmark

The urgency for energy transition is evident through the increasing demand for new technologies such as water electrolysers(WEs),which have the potential to generate green hydrogen using renewable *** paper aims to provide a comprehensive overview of the technical capabilities of commercially available WE system *** analysis is based on publicly accessible data gathered from 28 WE manufacturers worldwide with a total of 186 products,focusing on technology types and various technical characteristics of each WE system,including capacity,footprint,hydrogen output pressure,hydrogen purity and conversion *** analysis reveals that the current WE system solutions in the market exhibit diverse and varied ***,there is a lack of standardized product specifications adopted by *** underscores the urgent need for the development of frameworks and *** such standards is crucial for enhancing clarity and understanding,facilitating efficient comparisons and selection processes,and supporting the future advancement of WE technologies and WE-enabled Power-to-X applications on a global scale.

关键词： data analysis hydrogen Power-to-X standards water electrolyser system