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Light(Science & Applications) 2014年第1期3卷 5-12页

作者： Byoungchoo Park soo hong yun Chan Youn Cho Young Chan Kim Jung Chul Shin hong Goo Jeon Yoon Ho Huh Inchan Hwang Ku Youn Baik Young In Lee Han Sup Uhm Guang Sup Cho Eun Ha Choi Department of Electrical and Biological Physics Kwangwoon UniversitySeoul 139-701Republic of Korea Department of Electronic Materials Engineering Kwangwoon UniversitySeoul 139-701Republic of Korea

Herein,we report on surface plasmon(SP)-sensitive semitransparent inverted polymer photovoltaic(PV)devices that are based on multilayered material systems consisting of poly(3-hexylthiophene):fullerene-derivative bulk-heterojunction PV layers and thin gold or silver *** demonstrate that these PV devices allow the simultaneous generation of both electrical power and SPs on their anodes for photoexcitation just above the optical absorption edge of the PV layers,resulting not only in attenuated total reflection,but also in attenuated photocurrent generation(APG)under the SP resonance(SPR)***,we also confirm that the biomolecular interaction of biotin–streptavidin on the PV devices can be precisely detected via apparent SPR angle shifts in the APG spectra,even without the need for complex attenuated total reflection *** highlight our view that APG measurements made using these PV devices show great potential for the development of future generations of compact and highly sensitive SPR-based optical sensors.

关键词： attenuated total reflection optical sensors photocurrent generation polymer photovoltaic devices surface plasmon

Enrichment by air classification of indium components from In-containing scrap powders scraped by sand-blasting chamber shields of sputter coaters

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Rare Metals 2010年第1期29卷 1-8页

作者： Sungkyu Lee soo-Bok Jeong Hang-Chul Jung Hyun Seon hong Yongseung yun Sang Mo Woo Plant Engineering Center Institute for Advanced Engineering633-2 Goan-ri Baegam-myeon Cheoin-gu Yongin-si Gyeonggi-do 449-863 Korea Division of Chemical and Materials Engineering Ajou University 5 Wonchon Youngtong Suwon Gyeonggi-do 443-749 Korea Minerals and Materials Processing Division Korea Institute of Geo-science and Mineral Resources (KIGAM) 30 Gajeong-dong Yuseong-gu Daejeon 305-350 Korea Plant Engineering Center Institute for Advanced Engineering633-2 Goan-ri Baegam-myeon Cheoin-gu Yongin-siGyeonggi-do 449-863 Korea 9 Digit Co. Ltd. 20BL-10L Namdong Industrial Complex428-9 Nonhyeon-dong Namdong-gu Incheon 405-848 Korea

Raw scrap powders containing 10 wt.% In were recovered by sand-blasting chamber shields of sputter coaters and used as a sole source of indium components for both sieving and air-classification. Sieving was performed first as a feasibility test, and enrichment of indium component was possible up to 19 wt.% with a mesh size of 635. With this experimental basis, the raw scrap powders were air-classified into 12 lots according to the revolution per minute （r/min） of a single horizontally arranged classifying wheel： 4000, 6000, 8000, 10000, 12000, and 14000 r/rain. The particle cut size varied from 56 to 5 μm with turbo wheel speeds corresponding to 4000 to 14000 r/min, respectively, and enrichment of indium component was possible in fine overflow fractions at all turbo wheel speeds while the indium components were not concentrated in all of the coarse underflow fractions. The grade of the indium components became higher with decreasing particle size of the air-classified scrap powders, with the highest grade obtained in the fine overflow fraction with a turbo wheel speed of 14000 r/min. The amount of indium in the fine overflow fractions varied between 15.9 wt.% and 31.5 wt.%. All in all, the grade or purity of the indium component improved rather significantly from 15.9 wt.% to 31.5 wt.% by air-classification, but this also resulted in overall decrease in recovery rate from 99.33% to 49.64%. Therefore, enrichment and separation of indium should be optimized for maximum recovery and grade of the indium components, which can be used as raw materials in the subsequent electro-refining processes.

关键词： indium air-classification recycling indium tin oxide gas-cyclone dry dispersion

Low-molecular-weight fucoidan inhibits the proliferation of melanoma via Bcl-2 phosphorylation and PTEN/AKT pathway

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Oncology Research 2024年第2期32卷 273-282页

作者： MINJI PARK CHULHWAN BANG WON-soo yun yun-MI JEONG T&R Biofab Co. Ltd.Seongnam-si13487Korea Department of Dermatology Seoul St.Mary’s HospitalCollege of MedicineThe Catholic University of KoreaSeoul02706Korea Department of Mechanical Engineering Tech University of KoreaSi-heung City15073Korea

Fucoidan,a sulfate polysaccharide obtained from brown seaweed,has various bioactive properties,including anti-inflammatory,anti-cancer,anti-viral,anti-oxidant,anti-coagulant,anti-thrombotic,anti-angiogenic,and anti-Helicobacter pylori ***,the effects of low-molecular-weight fucoidan(LMW-F)on melanoma cell lines and three dimensional(3D)cell culture models are not well *** study aimed to investigate the effects of LMW-F on A375 human melanoma cells and cryopreserved biospecimens derived from patients with advanced *** wave was used to fragment fucoidan derived from Fucus vesiculosus into smaller *** and live/dead assays showed that LMW-F inhibited cell proliferation in both A375 cells and patientderived melanoma explants in a 3D-printed collagen *** PTEN/AKT pathway was found to be involved in the anti-melanoma effects of *** blot analysis revealed that LMW-F reduced the phosphorylation of Bcl-2 at Thr 56,which was associated with the prevention of anti-apoptotic activity of cancer *** findings suggested that LMW-F could enhance anti-melanoma chemotherapy and improve the outcomes of patients with melanoma resistance.

关键词： Low-molecular-weight fucoidan Melanoma Patient-derived melanoma explants in a 3D-printed collagen scaffold Anti-melanoma effect PTEN-AKT-Bcl-2 network

H_2S Sensing Characteristics of Thin Film SnO_2 Sensor with N_2 Treatment

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稀有金属材料与工程 2006年第A03期35卷 385-388页

作者： Jong-Won Kim Kwang-Hyun yun Geon-Young Cha Gi-hong Rue Duk-Dong Lee Jeung-soo Huh Department of Nano-Science and Technology Sangyuk-Dong 1370Bukgu DaeguKorea Department of Materials Science and Metallurgy Sangyuk-Dong 1370Bukgu DaeguKorea School of Electronic Engineering Kyungpook National UniversitySangyuk-Dong 1370Bukgu DaeguKorea Department of Nano-Science and Technology Department of Materials Science and MetallurgySangyuk-Dong 1370Bukgu DaeguKorea

SnO_2 thin film sensors were fabricated by a thermal evaporation *** sensors were heated for thermal *** high porosity,SnO_2 thin film sensors were treated in a N_2 *** sensors that were treated with O_2 after being treated with N_2 showed 70 % sensitivity for 1×10~ -6) of H_2S,which is higher than the sensors that were only treated with O_*** Ni metal,as a catalyst,was evaporated on the thin film Sn on the Al_2O_3 *** sensor was heated to grow the Sn nanowire in a tube furnace with N_2 *** nanowire was heated for *** sensitivity of SnO_2 nanowire sensor was measured for 500×10~ -9) of H_*** selectivity of the SnO_2 nanowire sensor was compared with the thin film and the thick film SnO_*** sensor was measured for H_2S,CO,and NH_3 in this study.

关键词： SnO2 gas sensor N2 nanowire H2S

Effect of lifestyle modification on hepatocellular carcinoma incidence and mortality among patients with chronic hepatitis B

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World Journal of Gastroenterology 2023年第24期29卷 3843-3854页

作者： Yewan Park Danbee Kang Dong Hyun Sinn Hyunsoo Kim yun soo hong Juhee Cho Geum-Youn Gwak Department of Internal Medicine Kyung Hee University HospitalSeoul 02447South Korea Department of Digital Health SAIHSTSungkyunkwan UniversitySeoul 06355South Korea Department of Clinical Research Design and Evaluation SAIHSTSungkyunkwan UniversitySeoul 06355South Korea Center for Clinical Epidemiology Samsung Medical CenterSungkyunkwan UniversitySeoul 06351South Korea Department of Medicine Samsung Medical CenterSungkyunkwan University School of MedicineSeoul 06351South Korea Departments of Epidemiology and Medicine and Welch Center for PreventionEpidemiology and Clinical ResearchJohns Hopkins Medical InstitutionsBaltimoreMD 21287United States

BACKGROUND Research exploring the influence of healthier lifestyle modification(LSM)on the risk of hepatocellular carcinoma(HCC)in patients with chronic hepatitis B(CHB)is *** To emulate a target trial to determine the effect of LSM on HCC incidence and mortality among patients with CHB by large-scale population-based observational *** Among the patients with CHB enrolled in the Korean National Health Insurance Service between January 1,2009,and December 31,2017,those aged≥20 years who drank alcohol,smoked cigarettes,and were sedentary were *** included at least one LSM,including alcohol abstinence,smoking cessation,and regular *** primary outcome was HCC development,and the secondary outcome was liver-related *** used 2:1 propensity score matching to account for *** With 48766 patients in the LSM group and 103560 in the control group,the adjusted hazard ratio(HR)for incident HCC and liver-related mortality was 0.92[95%confidence interval(CI):0.87-0.96]and 0.92(95%CI:0.86-0.99)in the LSM group,respectively,compared with the control *** the LSM group,the adjusted HR(95%CI)for incident HCC was 0.84(0.76-0.94),0.87(0.81-0.94),and 1.08(1.00-1.16)for alcohol abstinence,smoking cessation,and regular exercise,*** adjusted HR(95%CI)for liver-related mortality was 0.92(0.80-1.06),0.81(0.72-0.91),and 1.15(1.04-1.27)for alcohol abstinence,smoking cessation,and regular exercise,*** LSM lowered the risk of HCC and mortality in patients with ***,active LSM,particularly alcohol abstinence and smoking cessation,should be encouraged in patients with CHB.

关键词： Lifestyle modification Chronic hepatitis B Hepatocellular carcinoma Cancer Mortality

Expression of prothymosin α predicts early recurrence and poor prognosis of hepatocellular carcinoma

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Hepatobiliary & Pancreatic Diseases International 2015年第2期14卷 171-177页

作者： Sang yun Ha Dae Hyun Song soo Hyun Hwang soo Youn Cho Cheol-Keun Park Department of Pathology Samsung Medical CenterSungkyunkwan University School of Medicine

BACKGROUND：Prothymosinα（PTMA）is a nuclear oncoprotein-transcription factor essential for cell cycle progression and *** was overexpressed in several human malignancies including hepatocellular carcinoma（HCC）.However,the prognostic significance of PTMA protein expression in HCC remains *** the present study,we evaluated PTMA protein expression by immunohistochemistry in order to elucidate the prognostic roles of PTMA in HCC ***： By immunohistochemistry, we investigated the expression of PTMA protein in tumor tissue from 226 HCC patients who underwent curative hepatectomy. Univariate and multivariate analyses were performed to evaluate its predic- tive value for tumor recurrence and survival of patients. The median follow-up period was 120 months. RESULTS： PTMA expression was observed in 162 （71.7%） of the 226 HCC patients and was significantly associated with higher Edmondson grade, microvascular invasion, intrahe- patic metastasis, higher American Joint Committee on Cancer （AJCC） T-stage, and lower albumin level. PTMA expression was an independent predictor of early recurrence （P=0.001）. PTMA expression showed an unfavorable influence on recurrence- free survival （RFS）（P〈0.001）. Subgroup analysis showed that among patients with tumor size _〈5.0 cm （140 patients）, patients at AJCC T-stage I （95 patients） and patients with a-fetoprotein ≤20 ng/mL （83 patients）, the differences in RFS between PTMA- positive and PTMA-negative groups were also statistically sig- nificant （P=0.017, P=0.002 and P=0.002, respectively）. In addi- tion, PTMA expression was an independent predictor of shorter RFS （P=0.011）. PTMA expression showed an unfavorable influ- ence on overall survival （P=0.014）, but was not an independent predictor of shorter overall survival （P=0.161）. CONCLUSIONS： PTMA protein expression might be a novel predictor of early recurrence and RFS in HCC patients, even those at early stage or with a-fetoprotein-negative after curative hep

关键词： prothymosin a hepatocellular carcinoma recurrence

Tunnel flexibility effect on the ground surface acceleration response

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Earthquake Engineering and Engineering Vibration 2016年第3期15卷 457-476页

作者： Mohammad Hassan Baziar asoud Rabeti Moghadam yun Wook Choo Dong-soo Kim Center of Excellence for Fundamental Studies in Structural Engineering School of Civil EngineeringIran University of Science and TechnologyTehranIran School of Civil Engineering Iran University of Science and TechnologyTehran1ran Department of Civil and Environmental Engineering College of EngineeringKongju National UniversityChungnam 330-717Republic of Korea Department of Civil and Environmental Engineering Korea Advanced Institute of Science&TechnologyDaejeon 305-701Republic of Korea

Flexibility of underground structures relative to the surrounding medium, referred to as the flexibility ratio, is an important factor that influences their dynamic interaction. This study investigates the flexibility effect of a box-shaped subway tunnel, resting directly on bedrock, on the ground surface acceleration response using a numerical model verified against dynamic centrifuge test results. A comparison of the ground surface acceleration response for tunnel models with different flexibility ratios revealed that the tunnels with different flexibility ratios influence the acceleration response at the ground surface in different ways. Tunnels with lower flexibility ratios have higher acceleration responses at short periods, whereas tunnels with higher flexibility ratios have higher acceleration responses at longer periods. The effect of the flexibility ratio on ground surface acceleration is more prominent in the high range of frequencies. Furthermore, as the flexibility ratio of the tunnel system increases, the acceleration response moves away from the free field response and shifts towards the longer periods. Therefore, the flexibility ratio of the underground tunnels influences the peak ground acceleration （PGA） at the ground surface, and may need to be considered in the seismic zonation of urban areas.

关键词： box-shaped tunnel flexibility ratio acceleration response ground surface centrifuge modeling numericalsimulation

Stabilizing lithium deposition within bimodal porous SiO_(2)-TiO_(2) microspheres as 3D host structure

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Nano Research 2024年第11期17卷 10179-10188页

作者： Noeul Kim Jae Hun Choi Min Kim Dae soo Jung yun Chan Kang Department of Materials Science and Engineering Korea University Anam-Dong Seongbuk-Gu Seoul 136-713 Republic of Korea Energy Storage Materials Center Korea Institute of Ceramic Engineering and Technology Soho-ro Jinju-si Gyeongnam-do 52851 Republic of Korea

Three-dimensional (3D) host materials for lithium metal anodes (LMAs) have gained attention because they can mitigate volume expansion and local current density through their large surface area and suppress the dendritic growth of lithium. Recent research on 3D host materials has focused on conductive materials;however, the benefits of 3D host materials cannot be fully utilized because lithium deposition begins at the top of the structure. Herein, we fabricate SiO_(2)-TiO_(2) composite microspheres with bimodal pore structures (bi-SiTiO) by simple spray pyrolysis. These microspheres effectively store lithium within the structure from the bottom of the electrode while preventing lithium dendrite formation. Focused ion beam-scanning transmission electron microscopy (FIB-STEM) analysis reveals that the lithiophilic properties of composite microspheres enhanced their effectiveness in storing lithium, with small pores acting as “lithium-ion sieves” for a uniform lithium-ion flux and large pores that provide sufficient volume for lithium deposition. The bi-SiTiO composite microspheres exhibit a high Coulombic efficiency of 98.5% over 200 cycles at 2.0 mA·cm^(−2) when operated in a lithium half-cell. With a high lithium loading of 5.0 mAh·cm^(−2), the symmetrical cell of the bi-SiTiO electrode sustains more than 900 h. A full cell coupled with an LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2) (NCM811) cathode also exhibits enhanced electrochemical properties in terms of cycling stability and rate capability.

关键词： lithium metal battery spray pyrolysis three-dimensional(3D)host materials bimodal pore structure lithiophilic materials

Nanoconfinement effect of nanoporous carbon electrodes for ionic liquid-based aluminum metal anode

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Journal of Energy Chemistry 2022年第11期31卷 121-127,I0005页

作者： Juhee Yoon Seongbak Moon Son Ha Hyung-Kyu Lim Hyoung-Joon Jin Young soo yun Program in Environmental and Polymer Engineering Inha UniversityIncheon 22212South Korea Department of Polymer Science and Engineering Inha UniversityIncheon 22212South Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul 02841South Korea Division of Chemical Engineering and Bioengineering Kangwon National UniversityGangwon-do 24341South Korea Department of Integrative Energy Engineering Korea UniversitySeoul 02841South Korea

Rechargeable aluminum batteries(RABs),which use earth-abundant and high-volumetric-capacity metal anodes(8040 m Ah cm-3),have great potential as next-generation power sources because they use cheaper resources to deliver higher energies,compared to current lithium ion ***,the mechanism of charge delivery in the newly developed,ionic liquid-based electrolytic system for RABs differs from that in conventional organic ***,targeted research efforts are required to address the large overpotentials and cycling decay encountered in the ionic liquid-based electrolytic *** this study,a nanoporous carbon(NPC)electrode with well-developed nanopores is used to develop a high-performance aluminum *** negatively charged nanopores can provide quenched dynamics of electrolyte molecules in the aluminum deposition process,resulting in an increased collision *** fast chemical equilibrium of anionic species induced by the facilitated anionic collisions leads to more favorable reduction reactions that form aluminum *** nanoconfinement effect causes separated nucleation and growth of aluminum nanoparticles in the multiple confined nanopores,leading to higher coulombic efficiencies and more stable cycling performance compared with macroporous carbon black and 2D stainless steel electrodes.

关键词： Nanoconfinement effect Nanoporous carbon Ionic liquid electrolyte Metal anode Aluminum batteries Multivalent batteries

Recoverable SnO_2-Based Sensors Promoted with MoO_3 and Sb_2O_3 for the Detection of DMMP

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稀有金属材料与工程 2006年第A03期35卷 155-156页

作者： Woo Suk Lee Ho yun Choi soo Chool Lee soo Jae Lee Duk Dong Lee Jeung soo Huh Jae Chang Kim Department of Chemical Engineering Kyungpook National UniversityDaegu 702-701Korea School of Electrical Engineering and Computer Science Kyungpook National UniversityDaegu 702-701Korea Department of Materials Science and Metallurgy Kyungpook National UniversityDaegu 702-701Korea

The sensitivity and the recovery behavior of SnO_2-based gas sensor prepared from a commercial SnO_2 powder were tested under the low concentration of DMMP(0.5μg/g) in the flow system at 350℃.In order to improve the sensitivity of the sensor,promoters such as NiO,Nb_2O_5,MoO_3,and Sb_2O_3 were added into SnO_2 *** sensitivities were increased up to 80% from 50% but they were not *** the SnO2-based gas sensor promoted with MoO_3 and Sb_2O_3 was recovered after detection of DMMP,although the recovery rate was *** particular,the SnO_2-based sensor promoted with 5wt% of MoO_3 and 1wt% of Sb_2O_3 simultaneously showed an complete recovery ability,though its sensitivity was 40% which was lower than that of SnO_2 gas sensor without *** ability was discussed in terms of catalytic roles of promoters.

关键词： SnO2 MoO3 Sb2O3 sensor,recovery DMMP