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The.influe.ce.of diffe.e.t contrace.tive.me.hods on vaginal microbiota: Clinical study

He.lth 2013年第7期5卷 19-24页

作者： sonia e. fosch Cristian Yone. Marta Trosse.o Omar Grosso Bioche.ist-Spe.ialist in Clinical Bacte.iology Servicio de Atención Médica Ministerio de Salud 25 de Mayo 254 Sa Pereira Santa Fe Argentina Facultad de.Inge.ie.ía y Cie.cias Hídricas Universidad Nacional del Litoral Pje El Pozo Santa Fe Argentina Programa de.Salud Se.ual y Re.roductiva e. e. Se.vicio de.Ate.ción Me.ica Ministerio de Salud 25 de Mayo 254 Sa Pereira Santa Fe Argentina Se.vicio de.Ate.ción Médica Ministerio de Salud 25 de Mayo 254 Sa Pereira Santa Fe Argentina

Obje.tive. The.aim of this work was to e.aluate.the.vaginal conte.t of wome. atte.ding family planning controls and its re.ationship with the.contrace.tive.practice.use. (oral contrace.tive.pills, intraute.ine.de.ice. condoms, or rhythm me.hod) as we.l as its re.ationship with the.lack of re.ular contrace.tion. De.ign: Obse.vational, de.criptive.study. Se.ting: Se.vicio de.Ate.ción Médica—Ministe.io de.Salud—Sa Pe.e.ra—Santa ***. Population: A total of 250 wome. we.e.studie. following the.BAVACO (balance.of the.vaginal conte.t). Me.hods: Standard me.hod, which include. the.we. mount te.t, and Gie.sa and Gram stain unde. the.Nuge.t score. Re.ults: Obtaine. from the.vaginal microbiota, the.vaginal inflammatory re.ponse. pre.e.ce.of ye.st and Trichomonas allowe. de.ining five.basic vaginal microbial state. which we.e.statistically re.ate. to contrace.tive.me.hods. Main Outcome.Me.sure.: The.association of e.ch of the.five.vaginal state. with the.diffe.e.t contrace.tive.practice. was de.e.mine. by X2 te.t, conside.ing p e.e.ce.(Program e.I-INFO 6. Ve.sion 6.04). Re.ults: A significantly positive.association was found be.we.n oral contrace.tive. and normal microbiota (OR 3.98 – p = 0.000);intraute.ine.de.ice.and bacte.ial vaginosis (OR 10.1 – p = 0.000);whe.e.s a ne.ative.re.ationship (OR 0.18 – p = 0.005) was found be.we.n oral contrace.tive. and bacte.ial vaginosis (OR 0.21 – p = 0.000). Conclusions: a) the.positive.association of combine. oral contrace.tive. with a normal microbiota indicate. a positive.tre.d of prote.tion, b) intraute.ine.de.ice. incre.se.whe.e.s oral contrace.tive. de.re.se.the.risk for bacte.ial vaginosis, while.oral contrace.tive. re.uce.the.fre.ue.cy.

关键词： Vaginal Dysfunction Vaginal Conte.t Vaginal State. Contrace.tion

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Lipid re.e.ve. and immune.de.e.se.in he.lthy and dise.se. migrating monarchs Danaus ple.ippus

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Curre.t Zoology 2013年第3期59卷 393-402页

作者： Dara A. SATTe.FIe.D Amy e. WRIGHT sonia ALTIZe. Odum School of e.ology University of Georgia Athens GA 30602 USA

Re.e.t studie. sugge.t that the.e.e.ge.ic de.ands of long-distance.migration might lowe. the.pool of re.ource. available.for costly immune.de.e.se.. More.ve., migration could amplify the.costs of parasitism if animals suffe.ing from para- site.induce. damage.or de.le.e. e.e.gy re.e.ve. are.le.s able.to migrate.long distance.. We.inve.tigate. re.ationships be.we.n long-distance.migration, infe.tion, and immunity in wild fall-migrating monarch butte.flie. Danaus ple.ippus. Monarchs migrate.annually from e.ste.n North Ame.ica to ce.tral Me.ico, accumulating lipids e.se.tial for migration and winte. survival as the. trave. southward. Monarchs are.commonly infe.te. by the.de.ilitating protozoan parasite.Ophryocystis e.e.troscirrha （Oe.. We.colle.te. data on lipid re.e.ve., parasite.loads, and two immune.me.sure. （he.ocyte.conce.tration and phe.oloxidase.activity） from wild monarchs migrating through north GA （USA） to ask whe.he. （1） parasite.infe.tion ne.ative.y affe.ts lipid re.e.ve., and （2） gre.te. inve.tme.t in lipid re.e.ve. is associate. with lowe. immune.me.sure.. Re.ults showe. that monarchs sample. late. in the.fall migration had lowe. but not significantly diffe.e.t immune.me.sure. and significantly highe. lipid re.e.ve. than those.sample. e.rlie.. Lipid me.sure. corre.ate. ne.ative.y but only ne.rly significantly with one.me.sure.of immune.de.e.se.（phe.oloxidase.activity） in both he.lthy and infe.te. monarchs, but did not de.e.d on monarch infe.tion status or parasite.load. The.e.re.ults provide.we.k support for a trade.off be.we.n e.e.gy re.e.ve. and immune.de.e.se.in migrants, and sugge.t that pre.iously-de.onstrate. costs of Oe.infe.tion for monarch migration are.not cause. by de.le.e. lipid re.e.ve. .

关键词： Butte.fly He.ocyte. Migration Ne.gre.arine Infe.tion e.e.gy re.e.ve.

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Influe.ce.of Contrace.tion on Basic Vaginal State.: A Prospe.tive.Study

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He.lth 2015年第2期7卷 238-244页

作者： sonia e.e.a fosch Cristian Yone. Marta Trosse.o Omar Grosso Be.triz Pe.azzi Se.vicio de.Ate.ción Médica Ministerio de Salud Sa Pereira Argentina Facultad de.Inge.ie.ía y Cie.cias Hídricas Universidad Nacional del Litoral Santa Fe Argentina De.artame.to de.Bioquímica Clínica Hospital de Clínicas Facultad de Farmacia y Bioquímica Universidad de Buenos Aires Buenos Aires Argentina

To e.aluate.the.influe.ce.of contrace.tive.me.hods on the.basic vaginal state. (BVSs) in wome. in fe.tile.age. 108 wome. consulting for birth control (14 - 45 ye.rs) we.e.include. in a prospe.tive.study. The.vaginal conte.t was sample. both be.ore.the. be.an using the.chose. contrace.tive.me.hod (se. be.ow) and thre. months late., and the. analyze. using the.Balance.of Vaginal Conte.t (BAVACO) me.hodology. Five.BVSs we.e.de.ine.: 1) normal microbiota;2) normal microbiota with vaginal inflammatory re.ction (VIR);3) inte.me.iate.microbiota;4) bacte.ial vaginosis and 5) non-spe.ific microbial vaginitis. The.following contrace.tive.me.hods we.e.conside.e.: combine. oral contrace.tive.pill (COCP), intraute.ine.de.ice.(IUD), condom (CON), the.rhythm me.hod (RHYT) and simultane.us double.prote.tion (COCP + CON). The.McNe.ar statistical te.t was use.. COCP (n = 71): 20 sample. re.aine. normal BVSs and two we.e.alte.e.;nine.out of the.49 alte.e. sample. re.urne. to normal;IUD (n = 4): two sample. modifie. the.r normal BVS to III and IV;CON (n = 25): the.VIR incre.se. in 20% of the.sample.;RHYT (n = 6): four sample. re.aine. the.normal BVS;and COCP + CON (n = 2): sample. pre.e.ve. the.r initial BVS (II). The.incre.se. fre.ue.cy of BVS I in the.COCP group was significant (x2 = 3.3;p = 0.04). The.re.ative.fre.ue.cy of e.ch BVS was significantly modifie., attribute. to the.type.of contrace.tive.me.hod use.. The.intake.of hormone. corre.ts alte.ations and re.ains a normal BVS. The.contrace.tive.me.hods that use.an e.te.nal factor of local contact e.the. maintain or alte. the.microbiota and VIR.

关键词： Contrace.tion Basic Vaginal State. Vaginal Conte.t

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A Symbolic-Nume.ic Approach for Parame.rizing Rule. Surface.

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Journal of Syste.s Scie.ce.& Comple.ity 2020年第3期33卷 799-820页

作者： PÉRe.-DÍAZ sonia SHe. Li-Yong Dpto.de.Física y Mate.áticas Universidad de Alcalá28871-Alcaláde HenaresMadridSpain School of Mathe.atical Scie.ce. University of Chinese Academy of SciencesBeijing 100049China

This pape. pre.e.ts symbolic algorithms to de.e.mine.whe.he. a give. surface.implicitly or parame.rically de.ine.)is a rational rule. surface.and find a prope. parame.rization of the.rule. ***,in practical applications,one.has to de.l with nume.ical obje.ts that are.give. approximate.y,probably be.ause.the. proce.d from an e.act data that has be.n pe.turbe. unde. some.pre.ious me.suring proce.s or *** the.e.nume.ical obje.ts,the.authors adapt the.symbolic algorithms pre.e.te. by me.ns of the.use.of nume.ical *** authors de.e.op nume.ic algorithms that allow to de.e.mine.rule. surface."close.to an input(not ne.e.sarily rule.)surface.and the.distance.be.we.n the.input and the.output surface.is compute..

关键词： Implicit re.re.e.tation nume.ic algorithm rule. surface standard parame.rization

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Mode.n planktonic foraminife.a from the.e.ste.n Indian Oce.n

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Acta Oce.nologica Sinica 2018年第10期37卷 46-63页

作者： MUNIR sonia SUN Jun Tianjin Ke. Laboratory of Marine.Re.ource. and Che.istry Tianjin University of Science and Technology Re.e.rch Ce.tre.for Indian Oce.n e.osyste. Tianjin University of Science and Technology

A brie. morphome.ric study of the.re.e.t planktonic foraminife.a in the.e.ste.n Indian Oce.n was provide. with the.taxonomic ke. to spe.ie., synonyms, Se. microphotographs of she.ls and chambe. arrays. By re.e.t classification, curre.tly 20 spe.ie. re.re.e.ting 13 ge.e.a and 6 familie. （Cande.inidae. He.e.ohe.icoidae. He.be.ge.lidae. Hige.ige.inoidae. Globige.inoidae. and Globorotaloidae. ide.tifie. from the.planktonic mate.ial of the.e.ste.n Indian Oce.n up to a de.th of 200 m. The.r distribution in wate. （0-200 m） also re.orts on the.ne. range.of e.pansion in the.e.ste.n Indian Oce.n, with De.tigloborotalia anfracta, Hastige.ina pe.agica, Stre.tochilus globige.us, Globige.ine.la calida, Globige.ine.la adamsi, Orcadia re.de.ii, Te.uite.la parke.ae. Te.uite.la compre.sa, re.orte. for the.first time.in this study are.. In ge.e.al, only around 50 planktonic spe.ie. are.valid worldwide. more.spe.ifically the.spe.ie., e.g., H. pe.agica, G. calida, G. adamsi, S. globige.us, O. rie.e.i, T. parke.ae. T. compre.sa, which occur in the.e.ste.n Indian Oce.n to fill the.the.paucity of the.re.e.t re.ional taxonomic lite.ature.and the.proble.atic ide.tification from the.e.ste.n Indian Oce.n. This work aims to bridge.this gap and he.p scie.tists, manage.s, e.ucators and stude.ts to ide.tify plankton foraminife.s by using spe.ie. note. and image..

关键词： planktonic foraminife.ida He.e.ohe.icoidae He.be.ge.lidae.and Hige.ige.inoidae Globige.inoidae.and Globorotaloidae e.ste.n Indian Oce.n

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The.first snapshot study on horizontal distribution and ide.tification of five.pe.itrich ciliate. (Ge.us Vortice.la Linnae.s and Zoothamnium Bory de.St. Vince.t) from the.e.ste.n Indian Oce.n

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Acta Oce.nologica Sinica 2018年第10期37卷 79-85页

e.ipont pe.itrich ciliate. are.one.of the.most se.silie.protists that attache. to the.substrate.of zooplankton communitie. e.pe.ially cope.ods and crustace.ns. Pe.itrich ciliate. can be.solitary or colonial form found from the.coastal zone. and e.bayme.t around the.world. Pre.e.t re.e.rch re.ort is the.first snapshot study of the.pe.itrich ciliate. and the.horizontal distribution in ope. wate.s from surface.to 200 m de.th in the.e.ste.n Indian Oce.n. Re.e.tly, five.pe.itrich ciliate., e.g., Vortice.la oce.nica, Zootharnnium alte.nans, Z. alrashe.di, Z. pe.agicum, and Z. marinum we.e.colle.te. from plankton ne. tow sample. during the.cruise.from April 10 to May 13, 2014. The.characte.istics of the.pe.itrich ciliate.we.e.de.e.mine. according to the.shape.of the.zooids, the.ciliary structure.and the.stalks. The.morphome.ric shape. size. and characte.s also e.plaine. by e.amination unde. light/scanning e.e.tron microscopy. Vortice.la oce.nica and Z. pe.agicum showe. the.r association with host such as diatom （i.e. Chae.oce.os coarctatus） and cope.od （Oithona bre.icornis） including some.individuals around the.dinoflage.late.spe.ie. （Ce.aitum tripose.. The.distribution of the.e.se.silid ciliate. was dominate. by the.V. oce.nica, Z. pe.agicum and Z. rnarinurn at the.southe.st zone.while.the.large.colonie. of Z. alrashe.di obse.ve. at the.Bay of Be.gal. This distribution can be.influe.ce. by substrate.availability like.diatom （Ch. coarctatus） and cope.ods （O. bre.icornis）.

关键词： Vortice.la oce.nica Zoothamnium alte.nans Zoothamnium alrashe.di Zoothamnium marinum Zoothamnium pe.agicum e.ste.n Indian Oce.n

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e.tract of Codiae.m luzonicum Me.r. ove.come. multidrug re.istance.in human colon cance. ce.ls by modulating P-glycoprote.n

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Asian Pacific Journal of Tropical Biome.icine 2022年第9期12卷 400-410页

作者： Re.ina Joyce.e.Fe.re. Marc Justin C.Ong sonia D.Jacinto Institute.of Biology University of the Philippines DilimanQuezon CityMetro ManilaPhilippines

Obje.tive.To inve.tigate.anti-multidrug re.istance.MDR)activity and safe.y of the.bioactive.fraction(CL11)from Codiae.m luzonicum crude.le.f ***:Cytotoxic activity of CL11 against MDR and nonre.istant colon cance. ce.ls was asse.se. using MTT *** of ce.l de.th was inve.tigate. by anne.in V-propidium iodide.staining,TUNe.,and JC-1 *** e.amine.me.hanism of action,the.e.fe.t on the.e.pre.sion and function of the.MDR-implicate. prote.n P-glycoprote.n was te.te. using We.te.n blotting and calce.n assay,***:CL11 had an e.50 of 0.18,1.03 and 38.52µg/mL against HCT-15,HCT-15/Dox and HCT116,*** was me.iate. by inhibition of P-glycoprote.n function and *** mode.of ce.l de.th involve. mitochondrial me.brane.de.olarization and was mostly non-apoptotic at e.50 conce.trations against HCT-15 and HCT-15/***:Fraction CL11 of Codiae.m luzonicum induce. nonapoptotic ce.l de.th in MDR cance. ce.ls by ove.coming MDR through inhibition of P-glycoprote.n e.pre.sion and function.

关键词： Natural product Le.f e.tract Codiae.m luzonicum MDR cance. P-gp inhibitor Colore.tal cance.

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Pulse. lase. ablation in liquid of sp-carbon chains:Status and re.e.t advance.

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Chine.e.Physics B 2022年第12期31卷 325-345页

作者： Pie.ro Marabotti sonia Pe.giani Ale.sandro Vidale.Carlo Spartaco Casari De.artme.t of e.e.gy Politecnico di MilanoVia Ponzio 34/320133MilanoItaly

This re.ie. provide. a discussion of the.curre.t state.of re.e.rch on sp-carbon chains synthe.ize. by pulse. lase. ablation in *** re.e.t ye.rs,pulse. lase. ablation in liquid(PLAL)has be.n wide.y e.ploye. for polyyne. synthe.is thanks to its fle.ibility with varying lase. parame.e.s,solve.ts,and *** allows the.control of sp-carbon chains prope.tie. as yie.d,le.gth,te.mination and *** many re.ie.s re.ate. to PLAL have.be.n publishe.,a compre.e.sive.work re.orting the.curre.t status and advance. re.ate. to the.synthe.is of sp-carbon chains by PLAL is still *** we.first re.ie. the.principle.of PLAL and the.me.hanisms of formation of sp-carbon *** we.discuss the.role.of lase. flue.ce.*** de.sity),solve.t,and targe. for sp-carbon chains ***,we.re.ort the.progre.s re.ate. to the.prolonge. stability of sp-carbon chains by PLAL e.capsulate. in polyme.ic *** re.ie. will be.a he.pful guide.for re.e.rche.s inte.e.te. in synthe.izing sp-carbon chains by PLAL.

关键词： pulse. lase. ablation in liquid sp-carbon chains carbyne carbon nanostructure.

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Translating curre.t biome.ical the.apie. for long duration,de.p space.missions

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Pre.ision Clinical Me.icine 2019年第4期2卷 259-269页

作者： sonia Iosim Matthe. MacKay Craig We.tove. Christophe. e.Mason De.artme.t of Physiology and Biophysics Weill Cornell MedicineNew YorkNY 10021USA The.HRH Prince.Alwale.d Bin Talal Bin Abdulaziz Alsaud Institute.for Computational Biome.icine Weill Cornell MedicineNew YorkNY 10021USA The.Fe.l Family Brain and Mind Re.e.rch Institute Weill Cornell MedicineNew YorkNY 10021USA The.WorldQuant Initiative.for Quantitative.Pre.iction Weill Cornell MedicineNew YorkNY 10021USA

It is be.n shown that space.light-induce. mole.ular,ce.lular,and physiologic change. cause.alte.ations across many modalitie. of the.human body,including cardiovascular,musculoske.e.al,he.atological,immunological,ocular,and ne.rological *** Twin Study,a multi-ye.r,multi-omic study of human re.ponse.to space.light,provide. de.aile. and compre.e.sive.mole.ular and ce.lular maps of the.human re.ponse.to radiation,microgravity,isolation,and *** rich data ide.tifie. e.ige.e.ic,ge.e.e.pre.sion,inflammatory,and me.abolic re.ponse. to space.light,facilitating a be.te. biome.ical roadmap of fe.ture. that should be.monitore. and safe.guarde. in upcoming ***,by e.ploring ne. de.e.opme.ts in pre.clinical mode.s and clinical trials,we.can be.in to de.ign pote.tial ce.lular inte.ve.tions for e.ploration-class missions to Mars and pote.tially *** pape. will discuss the.ove.all risks astronauts face.during space.light,what is curre.tly known about human re.ponse.to the.e.risks,what pharmace.tical inte.ve.tions e.ist for use.in space.and which tools of pre.ision me.icine.and ce.lular e.gine.ring could be.applie. to ae.ospace.and astronaut me.icine.

关键词： NASA space.light Inte.national Space.Station NASA Twin Study multi-scale.omics

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Me.atonin modifie. SOX2^+ ce.l prolife.ation in de.tate.gyrus and modulate. SIRT1 and Me.P2 in long-te.m sle.p de.rivation

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Ne.ral Re.e.e.ation Re.e.rch 2019年第10期14卷 1787-1795页

作者： Alan Hinojosa-Godíne. Luis F. Jave.Suare. Mario Flore.-Soto Alma Y. Gálve.-Contre.as sonia Luquín e.ith Ore.on-Rome.o Oscar Gonzále.-Pére. Rocio e. Gonzále.-Castane.a Laboratorio de.Microscopía de.Alta Re.olución Departamento de NeurocienciasCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico Laboratorio de.Ne.rocie.cias Facultad de PsicologíaUniversidad de ColimaColimaMéxico División de.Inmunología Centro de Investigación Biomédica de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMéxico División de.Ne.rocie.cias Centro de Investigación Biomédica de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMéxico Instituto de.Inve.tigación e. Cie.cias Biomédicas (IICB) Departamento de Biología Molecular y GenómicaCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico Unidad de.Ate.ción e. Ne.rocie.cias Departamento de Neurociencias. Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajaraMéxico

Me.atonin is a ple.otropic mole.ule.that,afte. a short-te.m sle.p de.rivation,promote. the.prolife.ation of ne.ral ste. ce.ls in the.adult ***,this e.fe.t has not be.n obse.ve. in long-te.m sle.p *** pre.ise.me.hanism e.e.te. by me.atonin on the.modulation of ne.ral ste. ce.ls is not e.tire.y e.ucidate.,but e.ide.ce.indicate. that e.ige.e.ic re.ulators may be.involve. in this *** this study,we.inve.tigate. the.e.fe.t of me.atonin tre.tme.t during a 96-hour sle.p de.rivation and analyze. the.e.pre.sion of e.ige.e.ic modulators pre.icte. by computational te.t mining and ke.word *** re.ults showe. that the.administration of me.atonin unde. sle.p-de.rive. conditions incre.se. the.Me.P2 e.pre.sion and re.uce. the.SIRT1 e.pre.sion in the.de.tate.*** obse.ve. that le.-7 b,mir-132,and mir-124 we.e.highly e.pre.se. in the.de.tate.gyrus afte. me.atonin administration,but the. we.e.not modifie. by sle.p *** addition,we.found more.Sox2^+/5-bromo-2’-de.xyuridine.BrdU)^+ce.ls in the.subgranular zone.of the.sle.p-de.rive. group tre.te. with me.atonin than in the.untre.te. *** findings may support the.notion that me.atonin modifie. the.e.pre.sion of e.ige.e.ic me.iators that,in turn,re.ulate.the.prolife.ation of ne.ral proge.itor ce.ls in the.adult de.tate.gyrus unde. long-te.m sle.p-de.rive. *** proce.ure. pe.forme. in this study we.e.approve. by the.Animal e.hics Committe. of the.Unive.sity of Guadalajara,Me.ico(approval ***-16610)on January 2,2016.

关键词： sle.p-de.rivation me.atonin microRNA ne.roge.e.is Sirtuin 1 SIRT1 me.hyl-CpG-binding prote.n 2 Me.P2 e.ige.e.ic te.t-mining mir-9 le.-7b

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