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Cortical plasticity and nerve regeneration after peripheral nerve injury

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Neural Regeneration Research 2021年第8期16卷 1518-1523页

作者： Ci Li song-yang liu Wei Pi Pei-Xun Zhang Department of Orthopedics and Trauma Peking University People’s HospitalBeijingChina Key Laboratory of Trauma and Neural Regeneration Peking UniversityBeijingChina National Center for Trauma Medicine BeijingChina

With the development of neuroscience, substantial advances have been achieved in peripheral nerve regeneration over the past decades. However, peripheral nerve injury remains a critical public health problem because of the subsequent impairment or absence of sensorimotor function. Uncomfortable complications of peripheral nerve injury, such as chronic pain, can also cause problems for families and society. A number of studies have demonstrated that the proper functioning of the nervous system depends not only on a complete connection from the central nervous system to the surrounding targets at an anatomical level, but also on the continuous bilateral communication between the two. After peripheral nerve injury, the interruption of afferent and efferent signals can cause complex pathophysiological changes, including neurochemical alterations, modifications in the adaptability of excitatory and inhibitory neurons, and the reorganization of somatosensory and motor regions. This review discusses the close relationship between the cerebral cortex and peripheral nerves. We also focus on common therapies for peripheral nerve injury and summarize their potential mechanisms in relation to cortical plasticity. It has been suggested that cortical plasticity may be important for improving functional recovery after peripheral nerve damage. Further understanding of the potential common mechanisms between cortical reorganization and nerve injury will help to elucidate the pathophysiological processes of nerve injury, and may allow for the reduction of adverse consequences during peripheral nerve injury recovery. We also review the role that regulating reorganization mechanisms plays in functional recovery, and conclude with a suggestion to target cortical plasticity along with therapeutic interventions to promote peripheral nerve injury recovery.

关键词： cortical plasticity injury mechanisms nerve transfer neurorrhaphy peripheral nerve phantom limb pain recovery regeneration treatment

A review of the research on complex erosion by wind and water

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Journal of Geographical Sciences 2006年第2期16卷 231-241页

作者： song yang YAN Ping liu Lianyou College of Resources Science and Technology Key Laboratory of Environmental Change and NaturalDisaster the Ministry of Education of China Beijing Normal University Beijing 100875 China

Complex erosion by wind and water, which is also called aeolian-fluvial interactions, is an important erosion process and landscape in arid and semiarid regions. The effectiveness of links between wind and water process, spatial environmental transitions and temporal environmental change are the three main driving forces determining the geomorphologic significance of aeolian-fluvial interactions. As a complex interrelating and intercoupling system, complex erosion by wind and water has spatial- temporal variation features. The process of complex erosion by wind and water can be divided into palaeoenvironmental process and contemporary process. Early work in drylands has often been attributed to one of two schools advocating either an ＇aeolianist＇ or a ＇fluvialist＇ perspective, so it was not until the 1930s that the research on complex erosion by wind and water had been conducted. There are two obstacles restricting the research of complex erosion by wind and water. Firstly, how to transform in different temporal and spatial scales is still unsettled; and secondly, the research methodology is still immature. In the future, the mechanism and control of erosion, the complex soil erodibility in wind and water erosion will be the focus of research on complex erosion by wind and water.

关键词： complex erosion by wind and water aeolian-fluvial interactions semiarid regions sediment contemporary process

Approximately Bi-Similar Symbolic Model for Discretetime Interconnected Switched System

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IEEE/CAA Journal of Automatica Sinica 2024年第10期11卷 2185-2187页

作者： yang song Yongzhuang liu Wanqing Zhao School of Mechatronic Engineering and Automation Shanghai UniversityShanghai 200444China School of Computing Newcastle UniversityNewcastle upon Tyne NE45TGUK

Dear Editor,This letter concerns the development of approximately bi-similar symbolic models for a discrete-time interconnected switched system(DT-ISS).The DT-ISS under consideration is formed by connecting multiple switched systems known as component switched systems(CSSs).Although the problem of constructing approximately bi-similar symbolic models for DT-ISS has been addressed in some literature,the previous works have relied on the assumption that all the subsystems of CSSs are incrementally input-state stable.

关键词： approximate symbolic connected

An electroencephalography-based human-machine interface combined with contralateral C7 transfer in the treatment of brachial plexus injury

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Neural Regeneration Research 2022年第12期17卷 2600-2605页

作者： Meng Zhang Ci Li song-yang liu Feng-Shi Zhang Pei-Xun Zhang Department of Orthopedics and Trauma Peking University People’s HospitalBeijingChina Key Laboratory of Trauma and Neural Regeneration Peking UniversityBeijingChina National Center for Trauma Medicine BeijingChina

Transferring the contralateral C7 nerve root to the median or radial nerve has become an important means of repairing brachial plexus nerve ***,outcomes have been ***(EEG)-based human-machine interfaces have achieved promising results in promoting neurological recovery by controlling a distal exoskeleton to perform functional limb exercises early after nerve injury,which maintains target muscle activity and promotes the neurological rehabilitation *** review summarizes the progress of research in EEG-based human-machine interface combined with contralateral C7 transfer repair of brachial plexus nerve *** transfer may result in loss of nerve function in the donor area,so only nerves with minimal impact on the donor area,such as the C7 nerve,should be selected as the *** tendon transfer does not fully restore optimal joint function,so multiple functions often need to be reestablished *** with traditional manual rehabilitation,EEG-based human-machine interfaces have the potential to maximize patient initiative and promote nerve regeneration and cortical remodeling,which facilitates neurological *** the early stages of brachial plexus injury treatment,the use of an EEG-based human-machine interface combined with contralateral C7 transfer can facilitate postoperative neurological recovery by making full use of the brain’s computational capabilities and actively controlling functional exercise with the aid of external *** can also prevent disuse atrophy of muscles and target organs and maintain neuromuscular junction *** cortical remodeling is also particularly important for neurological recovery after contralateral C7 *** studies are needed to investigate the mechanism by which early movement delays neuromuscular junction damage and promotes cortical *** this mechanism should help guide the development of neurolog

关键词： arm injuries brachial plexus brain-computer interfaces nerve transfer nerve regeneration nerve tissue neurofeedback neurological rehabilitation user-computer interface

Symbology of Feynman integrals from twistor geometries

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Science China(Physics,Mechanics & Astronomy) 2024年第3期67卷 44-59页

作者： song He Jiahao liu Yichao Tang Qinglin yang School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUCASHangzhou 310024China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China International Centre for Theoretical Physics Asia-Pacific Beijing 100049 Peng Huanwu Center for Fundamental Theory Hefei 230026China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China

We study the symbology of planar Feynman integrals in dimensional regularization by considering geometric configurations in momentum twistor space corresponding to their leading singularities(LS). Cutting propagators in momentum twistor space amounts to intersecting lines associated with loop and external dual momenta, including the special line associated with the point at infinity, which breaks dual conformal symmetry. We show that cross-ratios of intersection points on these lines, especially those on the infinity line, naturally produce symbol letters for Feynman integrals in D = 4-2∈, which include and generalize their LS. At one loop, we obtain all symbol letters using intersection points from quadruple cuts for integrals up to pentagon kinematics with two massive corners, which agree perfectly with canonical differential equation(CDE) results. We then obtain all two-loop letters, for up to four-mass box and one-mass pentagon kinematics, by considering more intersections arising from two-loop cuts. Finally we comment on how cluster algebras appear from this construction, and importantly how we may extend the method to non-planar integrals.

关键词： Feynman integrals symbol letters twistor geometry

Potential application of radiant floor cooling systems for residential buildings in different climate zones

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Building Simulation 2024年第4期17卷 543-560页

作者： Mengying Cui yang song Yudong Mao Kaimin yang Jiying liu Zhe Tian School of Thermal Engineering Shandong Jianzhu UniversityJinan250101China School of Environmental Science and Engineering Tianjin UniversityTianjin300072China Key Lab of Building Environment and Energy of Tianjin Tianjin UniversityTianjin300072China

A radiant floor cooling system(RFCS)is a high-comfort and low energy consumption system suitable for residential *** floor systems usually work with fresh air,and their operating performance is affected by climatic *** and outdoor environmental disturbances and the system’s control strategy affect the indoor thermal comfort and energy efficiency of the ***,a multi-story residential building model was established in this *** system simulation program was used to study the operation dynamics of three control strategies of the RFCS based on the calibrated ***,the performance of the control strategies in five climate zones in China were compared using multi-criteria decision-making in *** results show that control strategy has a negligible effect on condensation risk,but the thermal comfort and economic performance differ for different control *** adaptability of different control strategies varies in different climate zones based on the consideration of multiple *** performance of the direct-ground cooling source system is better in Hot summer and warm winter *** variable air volume control strategy scores higher in Serve cold and Temperate zones,and the hours exceeding thermal comfort account for less than 3%of the total simulation ***,it is suggested to choose the RFCS control strategy for residential buildings according to the climate zone characteristics,to increase the energy *** results provide a reliable reference for implementing RFCSs in residential buildings.

关键词： control strategy radiant floor cooling system residential building energy efficiency climate zones

Wintertime Arctic Sea-Ice Decline Related to Multi-Year La Niña Events

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Advances in Atmospheric Sciences 2024年第9期41卷 1680-1690页

作者： Wenxiu ZHONG Qian SHI Qinghua yang Jiping liu song yang School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Guangdong Province Key Laboratory for Climate Change and Natural Disaster Studies Sun Yat-sen UniversityGuangzhou 510275China

Arctic sea ice has undergone a significant decline in the Barents-Kara Sea(BKS)since the late *** studies have shown that the decrease in sea ice caused by increased poleward moisture transport is modulated by tropical sea temperature changes(mainly referring to La Niña events).The occurrence of multi-year La Niña(MYLA)events has increased significantly in recent decades,and their impact on Arctic sea ice needs to be further *** this study,we investigate the relationship between sea-ice variation and different atmospheric diagnostics during MYLA and other La Niña(OTLA)*** decline in BKS sea ice during MYLA winters is significantly stronger than that during OTLA *** is because MYLA events tend to be accompanied by a warm Arctic-cold continent pattern with a barotropic high pressure blocked over the Urals ***,more frequent northward atmospheric rivers intrude into the BKS,intensifying longwave radiation downward to the underlying surface and melting the BKS sea ***,in the early winter of OTLA years,a negative North Atlantic Oscillation presents in the high latitudes of the Northern Hemisphere,which obstructs the atmospheric rivers to the south of *** infer that such a different response of BKS sea-ice decline to different La Niña events is related to stratospheric *** the rapid climate changes in the past,more frequent MYLA events may account for the substantial Arctic sea-ice loss in recent decades.

关键词： Arctic sea ice multi-year ENSO Ural blocking atmospheric river Barents-Kara Sea

Chronic administration of triclosan leads to liver fibrosis through hepcidin-ferroportin axis-mediated iron overload

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Journal of Environmental Sciences 2024年第3期137卷 144-154页

作者： Jing liu Lecong Zhang Fang Xu Ping Zhang yang song College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyang 550025China The Institute of Karst Wetland Ecology Guizhou Minzu UniversityGuiyang 550025China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China

Triclosan(TCS)has been manufactured as an antibacterial compound for half a ***,it is widely used in various personal care products;however,its potential adverse effects raise a lot of ***,we create a long-term oral administration mouse model and identify the corresponding hepatotoxicity of *** discover that daily intragastric administration of 10 mg/kg TCS to mice for 12 weeks results in severe hepatic *** study displays that hepatic iron increased 18%,23%and 29%upon oral TCS treatment for4,8 and 12 weeks,*** by hepatic iron variation,splenic and duodenal iron are increased,which indicates systemic iron *** only excessive iron accumulated in the liver,abnormal hepatic malondialdehyde,prostaglandin synthase 2 and glutathione peroxidase 4 are pointed to *** study uncovers that hepcidin expression increases 7%,10%,4%in serum and 2.4-,4.8-,and 2.3-fold on transcriptional levels upon TCS exposure for 4,8 and 12 weeks,*** together,the mice in the TCS-treated group show disordered systemic iron homeostasis via the upregulated hepatic hepcidin-ferroportin ***,both hepatic iron overload(systemic level)and hepatocyte ferroptosis(cellular level)are accused of TCS-induced liver ***■,an iron scavenger,significantly ameliorates TCS-induced liver *** summary,this study confirms the impact of TCS on liver fibrosis;a critical signal pathway is also *** significance of the current study is to prompt us to reevaluate the“pros and cons”of TCS applications.

关键词： Triclosan Iron metabolism Hepcidin Hepatotoxicity Liver fibrosis

Multi-UAVs Collaborative Path Planning in the Cramped Environment

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 529-538页

作者： Siyuan Feng Linzhi Zeng Jining liu Yi yang Wenjie song School of Automation Beijing Institute of TechnologyNanjing 210039China Nanjing Research Institute of Electronics Technology Nanjing 210039China Yichang Testing Technique Research Institute Yichang 443003China IEEE

Due to its flexibility and complementarity, the multiUAVs system is well adapted to complex and cramped workspaces, with great application potential in the search and rescue(SAR) and indoor goods delivery fields. However, safe and effective path planning of multiple unmanned aerial vehicles(UAVs)in the cramped environment is always challenging: conflicts with each other are frequent because of high-density flight paths, collision probability increases because of space constraints, and the search space increases significantly, including time scale, 3D scale and model scale. Thus, this paper proposes a hierarchical collaborative planning framework with a conflict avoidance module at the high level and a path generation module at the low level. The enhanced conflict-base search(ECBS) in our framework is improved to handle the conflicts in the global path planning and avoid the occurrence of local deadlock. And both the collision and kinematic models of UAVs are considered to improve path smoothness and flight safety. Moreover, we specifically designed and published the cramped environment test set containing various unique obstacles to evaluating our framework performance thoroughly. Experiments are carried out relying on Rviz, with multiple flight missions: random, opposite, and staggered, which showed that the proposed method can generate smooth cooperative paths without conflict for at least 60 UAVs in a few *** benchmark and source code are released in https://***/inin-xingtian/multi-UAVs-path-planner.

关键词： Collision avoidance conflict resolution multi-unmanned aerial vehicles(UAVs)system path planning