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Measurements of γ/γ' Lattice Misfit and γ' Volume Fraction for a Ru-containing Nickel-based Single Crystal Superalloy

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Journal of Materials Science & Technology 2011年第10期27卷 899-905页

作者： X.p. Tan J.L. Liu X p song T. Jin X.F. Sun Z.Q. Hu Superalloy Division Institute of Metal Research Chinese Academy of Sciences- Shenyang 110016 China Analysis and Testing Division Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China

A conventional X-ray difFractometer has been used to determine the -y/y＇ lattice misfit and γ＇ volume fraction for a Ru-containing nickel-based single crystal superalloy at room temperature. The rocking curve was used to characterize the distribution of subgrains. The diffraction peaks obtained by w-20 scan were used to determine the γ/γ＇ lattice misfit and γ＇ volume fraction. A three peaks fitting model was proposed. The peak fitting results are in good agreement with the model. The X-ray diffraction results indicate that the nickel-based single crystal superalloy was not a perfect monocrystalline material, which is comprised of many subgrains; and each subgrain also consists of large numbers of mosaic structures. In addition, two anomalous reflection phenomena were found during the experiment and discussed with respect to their occurrence and impact on the measurement. The experimental results show that the γ/γ＇ lattice misfit and ~/r volume fraction will be various at the different regions of its dendritic microstructure. The average γ/γ＇ lattice misfit and γ＇ volume fraction of the experimental alloy are approximately-0.2% and 70%, respectively. Furthermore, the γ＇ volume fraction calculated by atom microprobe （Ap） data is also basically consistent with the experimental results.

关键词： Nickel-based superalloy Microstructure X-ray diffraction Lattice misfit y' volume fraction

A red herring: An unusual case of pneumothorax

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World Journal of Emergency Medicine 2021年第2期12卷 160-161页

作者： Joseph H.Walline Koon-ho Cheung priscilla p.song Colin A.Graham Accident and Emergency Medicine Academic Unit Prince of Wales Hospitalthe Chinese University of Hong KongHong KongChina Department of Accident and Emergency Medicine Prince of Wales HospitalHong Kong Hospital AuthorityHong KongChina Centre for the Humanities and Medicine the University of Hong KongHong KongChina

Dear editor,A 67-year-old Chinese man presented to our emergency department (ED) complaining of right-sided chest wall *** noticed these symptoms three hours prior to arrival. He denied any shortness of breath or recent injury. past medical history was significant only for hypertension. Social history was significant for a history of smoking (40 packs per year).

关键词： sided editor hypertension

前瞻性队列中生殖因素对缺血性心脏病的终身累积效应

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中华高血压杂志 2024年第1期32卷 20-20页

作者： Hou L Liu W Sun W Cao J Shan S Feng Y Zhou Y Yuan C Li X song p 袁源(译) 郑武洪(审校) 不详

本研究基于终身雌激素高暴露降低心血管风险假说,探究终身雌激素暴露与缺血性心脏病(ischaemic heart disease,IHD)的关联性。方法:2004—2008年,采用生殖寿命(reproductive lifespan,RLS)、内源性雌激素暴露(endogenous oestrogen exposure,EEE)和总雌激素暴露(total oestrogen exposure,TEE)对中国Kadoorie生物样本库的绝经后女性进行生殖因素终身累积效应评估。

关键词：生物样本库缺血性心脏病内源性雌激素心血管风险绝经后女性生殖因素累积效应

Synthesis and Isolation of Diastereomers of Optically Active Cyclomercurated Ferrocenylimines

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Chinese Chemical Letters 2000年第11期11卷 975-978页

作者： Wu Y.J. Cui X.L. song M.p. Zhou N. Du C.X. Zhu Y. Department of Chemistry Zhengzhou University Zhengzhou 450052 China Henan prov. Lab. of Appl. Chemistry Zhengzhou University Zhengzhou 450052 China

Asymmetric cyclomercuration of chiral ferrocenylimines (+)-(R)-2 and (-)-(S)-2 with mercuric acetate and subsequent treatment by lithium chloride gave a mixture of diastereomeric cyclomercurated ferrocenylimines. The four enantiomeric pure compounds with both planar and central chirality were isolated from the two mixtures by the thin layer chromatography.

关键词： Sc KBr IR Hg Cl Synthesis and Isolation of Diastereomers of Optically Active Cyclomercurated Ferrocenylimines

The learning curve for transurethral enucleation with bipolar energy for benign prostate hyperplasia:a single-surgeon experience of 494 patients

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Asian Journal of Andrology 2024年第3期26卷 288-294页

作者： Byeongdo song Sang Hun song Seong Jin Jeong Department of Urology Seoul National University Bundang HospitalSeongnam 13620Korea Department of Urology Seoul National University College of MedicineSeoul 03080Korea

This study was performed to investigate the learning curve of transurethral enucleation with bipolar energy(TUEB)for benignprostatic *** study involved 494 consecutive patients who underwent TUEB for benign prostatic hyperplasia fromAugust 2018 to March 2022 by one surgeon(SJJ,Seoul National University Bundang Hospital,Seongnam,Korea).The patientswere followed up at 1 week,1 month,3 months,and 6 months *** evaluate the learning curve of TUEB,perioperativeparameters including the enucleation ratio(enucleated tissue weight/transitional zone volume),TUEB efficiency(enucleatedtissue weight/operation time),and enucleation efficiency(enucleated tissue weight/enucleation time)were *** and postoperative complications were also assessed,including the International prostate Symptom Score(IpSS),IpSSquality-of-life(QoL)score,and uroflowmetry *** patients’median age was 72(interquartile range[IQR]:66–78)years,and the estimated prostate volume and transitional zone volume were 63.0(IQR:46.0–90.6)ml and 37.1(IQR:24.0–60.0)ml,*** enucleation ratio,TUEB efficiency,and enucleation efficiency were 0.60(IQR:0.46–0.54)g ml−1,0.33(IQR:0.22–0.46)g min−1,and 0.50(IQR:0.35–0.72)g min−1,respectively,plateauing after 70 *** functional outcomes,including total IpSS,IpSS QoL score,and uroflowmetry outcomes,significantly improved at 6 months after TUEB(all ppatients developed complications after TUEB,21.5%of whom experienced major complications(Clavien–Dindo grade≥3).The rate of major complications declined as the number ofTUEB cases increased(p=0.013).Our results suggest that the efficiency of TUEB stabilized within 70 procedures.

关键词： benign prostate hyperplasia learning curve perioperative efficiency prostate transurethral enucleation with bipolar energy

Dietary Macleaya cordata extract supplementation improves the growth performance and gut health of broiler chickens with necrotic enteritis

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Journal of Animal Science and Biotechnology 2024年第1期15卷 374-395页

作者： Bochen song Jie He Xue pan Linglian Kong Chuanpi Xiao Chake Keerqin Zhigang song Key Laboratory of Efficient Utilization of Non‑Grain Feed Resources College of Animal Science and TechnologyShandong Agricultural UniversityTaian 271018ShandongChina Center for Mitochondria and Healthy Ageing College of Life SciencesYantai UniversityYantai 264005ShandongChina precision Livestock and Nutrition Unit University of LiègeGembloux Agro‑Bio TechGemblouxBelgium phytobiotics(Jiangsu)Biotech Co. Ltd.Jintan 213200China

Background The poultry industry needs effective antibiotic alternatives to control outbreaks of necrotic enteritis(NE)caused by Clostridium *** The aim of this study was to investigate the effects of dietary supplementation with Macleaya cordata extract(MCE)on the immune function and gut microbiota of broilers with NE.A total of 2881-day-old broiler chicks were randomly assigned to a 2×2 factorial arrangement with two concentrations of dietary MCE supplementation(0 or 350 mg/kg of diet)and two disease challenge statuses(control or NE).Results The results revealed that NE significantly increased the feed conversion rate(FCR),mortality,intestinal lesion score,the levels of IL-1β,IL-17 and IFN-γ/IL-4 in serum and IL-17/IL-10 in the jejunal mucosa,m RNA levels of TLR2,IFN-γand p Ig R in the jejunum,and Clostridium perfringens concentrations in the *** significantly decreased the body weight(BW),body weight gain(BWG),jejunal villus height,V/C,m RNA level of AMpK-α1 in jejunum,IL-4 level in the jejunal mucosa and lactic acid bacteria abundance in the *** significantly increased BW,BWG,jejunal villus height,V/C,m RNA levels of occludin,ZO-1 and AMpK-α1 in the jejunum,the levels of Ig A and Ig G in serum and IL-10 in the jejunal mucosa and m RNA levels of NF-κB,IL-10 and MHC-II in the ***,MCE significantly decreased the FCR,mortality,intestinal lesion score,jejunal crypt depth,the levels of IFN-γand IL-17 in serum and IL-17/IL-10 in the jejunal mucosa,Clostridium perfringens concentrations in the cecum,and m RNA levels of IL-17/IL-10 in the ***,NE significantly increased the abundance of bacteria that are associated with inflammation,obesity and depression(Alistipes,Barnesiella,Intestinimonas,RF39 and UCG-005)and significantly decreased the abundance of short-chain fatty acid(SCFA)-producing bacteria(Anaerotruncus,Butyricicoccus and Bacteroides)in the *** significantly increased the abundance of SCFA-producing b

关键词： Broiler chicken Gut microbiota Immune function Macleaya cordata extract Necrotic enteritis

Dynamic analysis and bifurcation control of a delayed fractional-order eco-epidemiological migratory bird model with fear effect

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International Journal of Biomathematics 2024年第3期17卷 1-33页

作者： Caihong song Ning Li College of Sciences Northeastern University 110819 ShenyangLiaoningP.R.China

In this paper,a new delayed fractional-order model including susceptible migratory birds,infected migratory birds and predators is proposed to discuss the spread of diseases among migratory *** of predators is considered in the model,as fear can reduce the reproduction rate and disease transmission rate among ***,some basic mathematical results of the proposed model are ***,time delay is regarded as a bifurcation parameter,and the delay-induced bifurcation conditions for such an uncontrolled system are established.A novel periodic pulse feedback controller is proposed to suppress the bifurcation *** is found that the control scheme can successfully suppress the bifurcation behavior of the system,and the pulse width can be arbitrarily selected on the premise of ensuring the control *** with the traditional time-delay feedback controller,the control scheme proposed in this paper has more advantages in practical application,which not only embodies the advantages of low control cost and easy operation but also caters to the periodic changes of the *** proposed control scheme,in particular,remains effective even after the system has been disrupted by a *** simulation verifies the correctness of the theoretical results.

关键词： Delayed fractional-order migratory birds fear Hopf bifurcation periodic pulse feedback

Mobile Crowdsourcing Task Allocation Based on Dynamic Self-Attention GANs

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Computers, Materials & Continua 2024年第4期79卷 607-622页

作者： Kai Wei song Yu Qingxian pan School of Computer and Control Engineering Yantai UniversityYantai264005China School of Computer and Information Science Southwest UniversityChongqing400715China

Crowdsourcing technology is widely recognized for its effectiveness in task scheduling and resource *** traditional methods for task allocation can help reduce costs and improve efficiency,they may encounter challenges when dealing with abnormal data flow nodes,leading to decreased allocation accuracy and *** address these issues,this study proposes a novel two-part invalid detection task allocation *** the first step,an anomaly detection model is developed using a dynamic self-attentive GAN to identify anomalous *** to the baseline method,the model achieves an approximately 4%increase in the F1 value on the public *** the second step of the framework,task allocation modeling is performed using a twopart graph matching *** phase introduces a p-queue KM algorithm that implements a more efficient optimization *** allocation efficiency is improved by approximately 23.83%compared to the baseline *** results confirm the effectiveness of the proposed framework in detecting abnormal data nodes,enhancing allocation precision,and achieving efficient allocation.

关键词： Mobile crowdsourcing task allocation anomaly detection GAN attention mechanisms

Combining cisplatin and a STING agonist into one molecule for metalloimmunotherapy of cancer

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National Science Review 2024年第1期11卷 107-119页

作者： Shuren Zhang Dongfan song Wenhao Yu Ji Li Xiaoyu Wang Yachao Li Zihan Zhao Qi Xue Jing Zhao Jie p.Li Zijian Guo State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringChemistry and Biomedicine Innovation Center (ChemBIC) Nanjing University Department of Urology Afflliated Drum Tower HospitalMedical SchoolNanjing University Nanchuang (Jiangsu)Institute of Chemistry and Health

Mounting evidence suggests that strategies combining DNA-damaging agents and stimulator of interferon genes(STING) agonists are promising cancer therapeutic regimens because they can amplify STING activation and remodel the immunosuppressive tumor microenvironment. However, a single molecular entity comprising both agents has not yet been developed. Herein, we designed two ptIV-MSA-2 conjugates(Ⅰand Ⅱ) containing the DNA-damaging chemotherapeutic drug cisplatin and the innate immuneactivating STING agonist MSA-2; these conjugates showed great potential as multispecific small-molecule drugs against pancreatic cancer. Mechanistic studies revealed that conjugate Ⅰ upregulated the expression of transcripts associated with innate immunity and metabolism in cancer cells, significantly differing from cisplatin and MSA-2. An analysis of the tumor microenvironment demonstrated that conjugate I could enhance the infiltration of natural killer(NK) cells into tumors and promote the activation of T cells, NK cells and dendritic cells in tumor tissues. These findings indicated that conjugate I, which was created by incorporating a pt chemotherapeutic drug and STING agonist into one molecule, is a promising and potent anticancer drug candidate, opening new avenues for small-molecule-based cancer metalloimmunotherapy.

关键词： platinum drug STING agonist single-molecule multitarget metalloimmunology