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Effects of L-arginine supplementation on glycemic profile: Evidence from a systematic review and meta-analysis of clinical trials

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Journal of Integrative Medicine 2020年第4期18卷 284-291页

作者： Esmaeil Yousefi Rad Behzad Nazarian somayeh saboori Ebrahim Falahi Azita Hekmatdoost Nutritional Health Research Center Lorestan University of Medical SciencesKhorramabad ***Iran Student Research Committee Lorestan University of Medical SciencesKhorramabad ***Iran Department of Clinical Nutrition and Dietetics Faculty of Nutrition and Food TechnologyNational Nutrition and Food TechnologyResearch InstituteShahid Beheshti University of Medical SciencesTehran ***Iran Division of Gastroenterology Hepatology and NutritionBritish Columbia’s Children’s Hospital and Child and Family Research Institutethe University of British ColumbiaBritish Columbia ***Canada

Background:The effects of l-arginine supplementation on indices of glycemic control and the role of many factors influencing this intervention have been controversial in clinical ***:This meta-analysis was performed to assess the effects of l-arginine supplementation on indices of glycemic control,including fasting blood glucose(FBG),hemoglobin A1c(HbA1c),serum insulin and homeostatic model assessment of insulin resistance(HOMA-IR)levels in randomized controlled trials(RCTs).Search strategy:This study conducted a systematic review of RCTs published in PubMed,Scopus,Web of Science,Cochrane Library and Embase,up to 5 May,*** criteria:Studies were included in this meta-analysis if they were RCTs with parallel design and reported sufficient data on participants before and after intervention,and outcomes of glycemic profile parameters in both the arginine supplementation and control *** extraction and analysis:The screening of titles and abstracts was performed independently by two *** articles were considered if they met the study’s inclusion *** quality of included studies was assessed by using the Cochrane Collaboration modified *** 710 articles retrieved in the initial search,only 10 trials were suitable for pooling the effects of arginine supplementation on serum glucose,insulin,HOMA-IR and HbA1c levels,with effect sizes of nine,eight,five and five,***:Pooled random-effect analysis revealed that l-arginine supplementation could significantly decrease FBG level(weighted mean difference[WMD]:3.35 mg/dL;95%confidence interval[CI]=[−6.55,−0.16];P=0.04)and serum insulin level(WMD:−2.19μIU/mL;95%CI=[−3.70,−0.67];P=0.005).However,the effects of l-arginine supplementation on HOMA-IR and HbA1c were not *** of subgroup analysis showed that supplementation with l-arginine could significantly decrease serum insulin levels when the dosage of l-arginine is>6.5 g/d(WMD:−3.49μIU/mL;95%CI=

关键词： l-arginine Fasting blood glucose Insulin resistance Hemoglobin A1c Glycemic profile Meta-analysis

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An Overview of PRP-Delivering Scaffolds for Bone and Cartilage Tissue Engineering

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Journal of Bionic Engineering 2024年第2期21卷 674-693页

作者： somayeh Baghersad Behzad Bolandi Rana Imani Shabnam Afaghi Samira Davoudinia Department of Textile Engineering Amirkabir University of Technology(Tehran Polytechnic)Tehran159163-4311Iran Department of Biomedical Engineering Amirkabir University of Technology(Tehran Polytechnic)Tehran159163-4311Iran

Tissue engineering is nowadays an emerging approach that aims to replace or regenerate diseased or damaged organs with engineered constructs. Considering the key role of growth factors (GFs) in the tissue regeneration process, these biomolecules are considered an important part of the tissue engineering process, so the presence of growth factors in engineered scaffolds can accelerate tissue regeneration by influencing the behavior of cells. Platelet-rich plasma (PRP), as an autologous source of a variety of growth factors, is considered a therapeutic agent for the treatment of degenerative diseases. Regarding its ability to promote the healing process and tissue regeneration, PRP therapy has attracted great attention in bone and cartilage tissue engineering. Incorporating PRP and its derivatives into engineered scaffolds not only bioactivates the scaffold, but the scaffold matrix also acts as a sustained and localized growth factor release system. In addition, the presence of a scaffold can promote the bioactivity of GFs by providing an environment that facilitates their interaction, leading to enhanced effects compared to their free form. This review presents a brief overview of PRP's role in bone and cartilage tissue regeneration with the main focus on scaffold-mediated PRP delivery. In addition, the classification of platelet-rich products, current extraction techniques, terminology, and scaffold bioactivation methods are presented to provide a better understanding of the basics and the key aspects that may affect the effectiveness of therapy in bone and cartilage tissue engineering.

关键词： Platelet-rich plasma Growth factors delivery Scaffold Bone Cartilage

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3D-Printed MOF Monoliths:Fabrication Strategies and Environmental Applications

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Nano-Micro Letters 2024年第12期16卷 358-405页

作者： Hossein Molavi Kamyar Mirzaei Mahdi Barjasteh Seyed Yahya Rahnamaee somayeh Saeedi Aliakbar Hassanpouryouzband Mashallah Rezakazemi Department of Chemistry Institute for Advanced Studies in Basic Science(IASBS)Zanjan 45137-66731Iran Department of Chemical and Biological Engineering University at BuffaloThe State University of New YorkBuffaloNY 14260USA Center for Nano-Science and Nanotechnology Institute for Convergence Science&TechnologySharif University of TechnologyTehran 15614Iran Department of Biomedical Engineering Amirkabir University of Technology(Tehran Polytechnic)Hafez Ave.P.O.Box 15875-4413TehranIran Grant Institute School of GeosciencesUniversity of EdinburghWest Main RoadEdinburgh EH93FEUK Faculty of Chemical and Materials Engineering Shahrood University of TechnologyShahroodP.O.Box ***Iran

Metal-organic frameworks(MOFs)have been extensively considered as one of the most promising types of porous and crystalline organic-inorganic materials,thanks to their large specific surface area,high porosity,tailorable structures and compositions,diverse functionalities,and well-controlled pore/size ***,most developed MOFs are in powder forms,which still have some technical challenges,including abrasion,dustiness,low packing densities,clogging,mass/heat transfer limitation,environmental pollution,and mechanical instability during the packing process,that restrict their applicability in industrial ***,in recent years,attention has focused on techniques to convert MOF powders into macroscopic materials like beads,membranes,monoliths,gel/sponges,and nanofibers to overcome these ***-dimensional(3D)printing technology has achieved much interest because it can produce many high-resolution macroscopic frameworks with complex shapes and geometries from digital ***,this review summarizes the combination of different 3D printing strategies with MOFs and MOF-based materials for fabricating 3D-printed MOF monoliths and their environmental applications,emphasizing water treatment and gas adsorption/separation ***,the various strategies for the fabrication of 3D-printed MOF monoliths,such as direct ink writing,seed-assisted in-situ growth,coordination replication from solid precursors,matrix incorporation,selective laser sintering,and digital light processing,are described with the relevant ***,future directions and challenges of 3D-printed MOF monoliths are also presented to better plan future trajectories in the shaping of MOF materials with improved control over the structure,composition,and textural properties of 3D-printed MOF monoliths.

关键词： MOFs 3D-printing Environmental remediation Shaping Monoliths

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Lithium-Metal Free Sulfur Battery Based on Waste Biomass Anode and Nano-Sized Li_(2)S Cathode

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Energy & Environmental Materials 2024年第2期7卷 39-47页

作者： Pejman Salimi Eleonora Venezia somayeh Taghavi Sebastiano Tieuli Lorenzo Carbone Mirko Prato Michela Signoretto Jianfeng Qiu Remo Proietti Zaccaria Istituto Italiano di Tecnologia via Morego 30Genoa 16163Italy Department of Chemistry and Industrial Chemistry University of Genovavia Dodecaneso 311-16146Genoa Italy CATMAT Lab Department of Molecular Sciences and NanosystemsCa'Foscari University Venice and INSTM ConsortiumRU of VeniceVia Torino 15530172Venezia Mestre Italy Department of Physics Shaoxing UniversityShaoxing 312000China

The realization of a stable lithium-metal free(LiMF)sulfur battery based on amorphous carbon anode and lithium sulfide(Li_(2)S)cathode is here *** particular,a biomass waste originating full-cell combining a carbonized brewer's spent grain(CBSG)biochar anode with a Li_(2)S-graphene composite cathode(Li_(2)S70Gr30)is *** design is particularly attractive for applying a cost-effective,high performance,environment friendly,and safe anode material,as an alternative to standard graphite and metallic lithium in emerging battery *** anodic and cathodic materials are characterized in terms of structure,morphology and composition through X-ray diffraction,scanning and transmission electron microscopy,X-ray photoelectron and Raman ***,an electrochemical characterization comprising galvanostatic cycling,rate capability and cyclic voltammetry tests were carried out both in half-cell and full-cell *** systematic investigation reveals that unlike graphite,the biochar electrode displays good compatibility with the electrolyte typically employed in sulfur *** CBSG/Li_(2)S70Gr30 full-cell demonstrates an initial charge and discharge capacities of 726 and 537 mAh g^(-1),respectively,at 0.05C with a coulombic efficiency of 74%.Moreover,it discloses a reversible capacity of 330 mAh g^(-1)(0.1 C)after over 300 *** on these achievements,the CBSG/Li_(2)S70Gr30 battery system can be considered as a promising energy storage solution for electric vehicles(EVs),especially when taking into account its easy scalability to an industrial level.

关键词： biochars ether-based electrolytes lithium sulfide lithium-metal free batteries superior cycling stability

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Representation of Family in the Narratives of Smiling Flower(Gol-e Khandān)

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Cultural and Religious Studies 2024年第7期12卷 409-416页

作者： somayeh Aghajani Kalkhoran Hankuk University of Foreign Studies SeoulSouth Korea

The development of a childs personality is profoundly influenced by the environmental stimuli after their *** this context,lullabies and childhood stories assume significant roles in this formative *** familial environment serves as the primary locus from which individuals acquire their beliefs and *** research investigates the portrayal of family dynamics within the narrative framework of the Persian story Smiling Flower(Gol-e Khandn).In the majority of narratives of this story,featuring the Laughing Flower,a magical agency is bestowed upon an infant girl,thereby shaping her *** analysis of this narratives themes prioritizes the familial element,particularly the central figures of parents,who play pivotal roles in the cultivation of the childs *** of parental representation within this narrative elucidates the prominence of the maternal figure,albeit acknowledging the undeniable influence exerted by the fathers demeanor and character on the childs trajectory.

关键词： Gol-e Khandān family father mother wife

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Necessary prerequisites for evidence-based practice:results of investigating nurses'informatics competency and information literacy skills

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Frontiers of Nursing 2024年第1期11卷 67-76页

作者： Jamileh Farokhzadian somayeh Jouparinejad Mahdieh Montazeri Elham Bakhshipour Amirreza Sabzi Fatemeh Falahati-Marvast Nursing Research Center Kerman University of Medical SciencesKermanIran Coronary Care Unit Shafa HospitalKerman University of Medical SciencesKermanIran Department of Health Information Sciences Faculty of Management and Medical Information SciencesKerman University of Medical SciencesKermanIran Medical Informatics Research Center Institute for Futures Studies in HealthKerman University of Medical SciencesKermanIran Biomechanics and Movement Sciences Interdisciplinary Program University of DelawareNewarkDEUSA Student Research Committee Shiraz University of Medical SciencesShirazIran Department of Health Technology Assessment School of Public HealthShahid Sadoughi University of Medical SciencesYazdIran

This study aimed to evaluate the correlation between nursing informatics(NI)competency and information literacy skills for evidencebased practice(EBP)among intensive care *** cross-sectional study was conducted on 184 nurses working in intensive care units(ICUs).The study data were collected through demographic information,Nursing Informatics Competency Assessment Tool(NICAT),and information literacy skills for EBP *** intensive care nurses received competent and low-moderate levels for the total scores of NI competency and information literacy skills,*** received a moderate score for the use of different information resources but a low score for information searching skills,different search features,and knowledge about search operators,and only 31.5%of the nurses selected the most appropriate *** competency and related subscales had a significant direct bidirectional correlation with information literacy skills for EBP and its subscales(P<0.05).Nurses require a high level of NI competency and information literacy for EBP to obtain up-to-date information and provide better care and *** planners and policymakers should develop interventions to enhance NI competency and information literacy skills among nurses and motivate them to use EBP in clinical settings.

关键词： evidence-based practice nursing informatics nursing informatics competency information literacy critical care nursing

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Protective effect of co-enzyme Q10 on testicular tissue and sperm parameters in adult male rats treated with Sunset Yellow FCF

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Asian pacific Journal of Reproduction 2024年第2期13卷 80-88页

作者： Rohollah Nazari somayeh Akbari Maryam Naseh Shayan Yousufzai Seyede Fatemeh Hosseini Fatemeh Karimi Histomorphometry and Stereology Research Center Shiraz University of Medical SciencesShirazIran Anatomy Department School of MedicineShiraz University of Medical SciencesShirazIran Student Research Committee Medical SchoolShiraz University of Medical SciencesShirazIran Faculty of Tabas School of NursingBirjand University of Medical SciencesBirjandIran

Objective:To determine the protective effect of co-enzyme Q10(CoQ10)on testicular tissue and sperm parameters in male rats treated with SunsetYellow ***:Sixty male Sprague-Dawley rats were randomly divided into 6 groups of the control,CoQ10(10 mg/kg/day),low dose of Sunset Yellow(2.5 mg/kg),high dose of Sunset Yellow(70 mg/kg),low dose of Sunset Yellow(2.5 mg/kg)plus CoQ10,and high dose of Sunset Yellow(70 mg/kg)plus *** drugs were administered via daily oral gavages for 6 *** the end of the experiment,sperm analysis,stereological and histological assessments of the testis were carried ***:The normal morphology(by 41.1%)and progressive spermatozoa(by 74.8%),testicle volume(by 33.4%),lumen volume(by 38.3%),interstitial tissue volume(by 44.7%),seminiferous tubule volume(by 40.7%),and number of spermatogonia(by 53.9%)and Leydig cells(by 70.7%)reduced in the rats that received high doses of Sunset Yellow in comparison to the control ***,all these alterations were recovered by CoQ10 treatment in the CoQ10 plus high dose of Sunset Yellow ***,low doses of Sunset Yellow did not affect different parameters of the testis and ***:CoQ10 could,to some extent,prevent structural changes of the testis induced by the high dose of SunsetYellow.

关键词： Sunset Yellow FCF Co-enzyme Q10 Testicle Sperm Stereology

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Reservoir Quality Controlling Factor of the Asmari Reservoir in an Oil Field in Dezful Embayment, SW Iran

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Open Journal of Geology 2024年第2期14卷 259-278页

作者： Katayoon Rezaeeparto Leila Fazli somayeh Parham Research Institute of Petroleum Industry Tehran Iran Islamic Azad University of Damavand Damavand Iran

The Asmari Formation Oligo-Miocene in age is one of the most important reservoir rocks in SW Iran and Zagros basin and composed of carbonate rocks and locally sandstones and evaporates. In this research, reservoir quality controlling factors have been investigated in a well in one of the oil fields in Dezful Embayment, SW Iran. Based on this research, depositional environment, diagenesis and fracturing have been affected on reservoir quality. 3 distinct depositional settings can be recognized in the studied interval including tidal flat, lagoon, and shoal. Among these depositional setting, shoal environment with ooid grainstone microfacies along with interparticle porosity shows good reservoir characteristics. Diagenetic processes also play an important role on reservoir quality;dolomitization and dissolution have positive effects on porosity and enhances reservoir quality, while cementation, anhydritization and compaction have negative effect on it. Fracturing is another important factor affected on the carbonate reservoirs especially in the Asmari Formation.

关键词： Asmari Formation Dezful Embayment Reservoir Quality Diagenesis Depositional Environment

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Exogenous application of bio-stimulants and growth retardants improve nutrient absorption and fiber quality in upland cotton

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Journal of Cotton Research 2024年第2期7卷 137-147页

作者： Al-Khayri Jameel M. Arif Muhammad Kareem Shadia Hama Salih Anwar Adeel Dehghanisanij Hossein Emami somayeh Yasmeen Azra Aftab Komal Negm Mohamed Department of Agricultural Biotechnology College of Agriculture and Food SciencesKing Faisal University31982 Al‑AhsaSaudi Arabia Water Resources Zone Irrigation Department PunjabD.G.KhanPakistan Department of Biotechnology and Crop Science College of Agricultural Engineering SciencesUniversity of SulaimaniSulaimaniIraq Department of Agronomy PMAS-Arid Agriculture UniversityRawalpindiPakistan Agricultural Research Education and Extension OrganizationAgricultural Engineering Research InstituteKarajAlborzIran Department of Water Engineering University of TabrizTabrizIran Department of Agronomy Bahauddin Zakariya UniversityMultanPakistan Department of Plant Breeding and Genetics Bahauddin Zakariya UniversityMultanPakistan Agricultural Research Center Cotton Research InstituteGiza 12619Egypt

Background Natural and synthetic plant growth regulators are essential for plant health,likewise these regulators also play a role in increasing organic production productivity and improving quality and yield *** the present study,we have evaluated the effects of foliar applied plant growth regulators,i.e.,moringa leaf extract(MLE)and mepiquat chloride(MC)alone and in combination MC and MLE on the conventional cotton cultivar(CIM 573)and transgenic one(CIM 598).The growth regulators were applied at the start of bloom,45 and 90 days after *** The application of MC and MLE at 90 days after blooming significantly improved the relative growth rate,net assimilation rate,the number of bolls per plant,and seed cotton ***,the combined application of MLE and MC at 90 days after blooming significantly boosted the nitrogen uptake in locules,as well as the phosphorus and potassium uptake in the leaves of both cotton *** application of MLE alone has considerably improved the nitrogen uptake in leaves,and phosphorus and potassium contents in locules of Bt and conventional cotton ***,Bt cotton treated with MLE at 90 days after blooming produced significantly higher ginning out turn and oil *** in combination(MLE+MC)at 90 days after blooming produced considerably higher micronaire value,fiber strength,and staple length in conventional *** The natural growth enhancer,MLE is a rich source of minerals and zeatin,improving the nutrient absorption and quality of cotton fiber in both conventional and Bt cotton cultivars.

关键词： Bio-stimulant Cotton Fiber quality Mepiquat chloride Moringa leaf extract Potassium accumulation Oil contents

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Prediction of the burden of road traffic injuries in Iran by 2030: Prevalence, death,and disability-adjusted life years

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Chinese Journal of Traumatology 2024年第4期27卷 242-248页

作者： Mozhgan Seif Sedigheh Edalat Ali Majidpour Azad Shirazi somayeh Alipouri Mohsen Bayati Non-communicable Diseases Research Center Department of EpidemiologySchool of HealthShiraz University of Medical SciencesShirazIran Health Human Resources Research Center School of Health Management and Information SciencesShiraz University of Medical SciencesShirazIran Health Policy Research Center Institute of HealthShiraz University of Medical SciencesShirazIran

Purpose:Road traffic accidents pose a global challenge with substantial human and economic *** a high incidence of road traffic injuries,leading to a significant burden on *** studyaims to predict the future burden of road traffic injuries in Iran until 2030,providing valuable insights forpolicy-making and interventions to improve road safety and reduce the associated human and ***:This analytical study utilized time series models,specifically autoregressive integrated movingaverage(ARIMA)and artificial neural networks(ANNs),to predict the burden of road traffic accidents byanalyzing past data to identify patterns and trends in Iran until *** required data related toprevalence,death,and disability-adjusted life years(DALYs)rates were collected from the Institute forHealth Metrics and Evaluation database and analyzed using R software and relevant modeling andstatistical analysis ***:Both prediction models,ARIMA and ANNs indicate that the prevalence rates(per 100,000)of allroad traffic injuries,except for motorcyclist road injuries which have an almost flat trend,remaining ataround 430,increase by *** on estimations of both models,the rates of death and DALYs due tomotor vehicle and pedestrian road traffic injuries *** motor vehicle road injuries,estimatedtrends decrease to approximately 520 DALYs and 10 ***,for pedestrian road injuries these ratesreached approximately 300 DALYs and 6 deaths,according to the *** cyclists and other roadtraffic injuries,the predicted DALY rates by the ANN model increase to almost 50 and 8,while predictionsconducted by the ARIMA model show a static trend,remaining at 40 and approximately ***,these rates for the prediction of death rate by the ANN model increased to 0.6 and 0.1,while predictionsconducted by the ARIMA model show a static trend,remaining at 0.43 and *** to the ANNmodel,the predicted rates of DALY and death for m

关键词： Accidents Traffic Accident prevention Motorcycles Road injury Forecasting

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