检索结果-南通市图书馆

Appropriate teaching and learning strategies for the architectural design process in pedagogic design studios

Frontiers of Architectural Research 2017年第2期6卷 204-217页

作者： Ashraf M. soliman Kingdom University Riffa Bahrain Minia University Minia Egypt

The national qualification framework of a country requires a certain level of knowledge and complexity of skills for an academic degree to be recognized. For architectural programs, student workload is heavy on design courses. Therefore, each course must be carefully developed to ensure that students are not overloaded. Teaching and learning strategies have different implications for courses, which occasionally result in overloading the students. This research aims to study the three main pillars of teaching and [earning strategies for each design phase in pedagogic design studios. The most appropriate model for each teaching and [earning strategy, including a set of the three main pillars, is then identified for each design phase. A practical strategy for managing design studios is also determined. The aforementioned three pillars are as follows： teaching and learning methods, assigned tasks or study aspects, and design communication techniques. Two research methods, namely, a literature review and a survey among design educators, are adopted. The literature review examines aspects that contribute to the design process and its phases, teaching methods, design skills, communication methods, and studio management strategies. On the basis of the literature review, the background of developments and practices in the design education process are used as constructive tools to develop the survey for design educators. Through the survey, the pillars of teaching and [earning strategies that are frequently practiced in design studios are evaluated. Results of this study are classified into three ranks using the nature break classification method for numerical values. Subsequently, three priority models that correspond to teaching and learning strategies, as welt as to the required skills and capabilities, are established. A group-based strategy with an interdisciplinary approach is also determined to be the most suitable technique for managing the pedagogy of architectural

关键词： Architectural design Studio teaching Learning strategy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Uncoupling tumor necrosis factor-αand interleukin-10 at tumor immune microenvironment of breast cancer through miR-17-5p/MALAT-1/H19 circuit

引用

BIOCELL 2022年第3期46卷 769-783页

作者： RAGHDA a.soliman RANA A.YOUNESS TAMER M.MANIE EMAD KHALLAF MOHAMED EL-SHAZLY MONA ABDELMOHSEN HEBA HANDOUSSA MOHAMED Z.GAD Pharmaceutical Biology Department Faculty of Pharmacy and BiotechnologyGerman University in CairoCairo11835Egypt School of Life and Medical Sciences University of Hertfordshire Hosted by Global Academic FoundationNew Administrative Capital11578Egypt Breast Surgery Department National Cancer InstituteCairo UniversityCairoEgypt General Surgery Department Faculty of MedicineCairo UniversityCairoEgypt Department of Phytochemistry National Research CentreGiza12622Egypt Biochemistry Department Faculty of Pharmacy and BiotechnologyGerman University in CairoCairo11835Egypt

Triple Negative Breast Cancer(TNBC)immunotherapy has recently shown promising ***,some TNBC patients presented with *** of the reasons was attributed to the excessive release of cytokines at the tumor microenvironment(TME)such as Tumor necrosis factor alpha(TNF-α)and Interleukin-10(IL-10).Fine regulation of these cytokines’levels via non-coding RNAs(ncRNAs)might alleviate the immune quiescent nature of TME at TNBC ***,the extrapolation of ncRNAs as therapeutic tools is highly ***,disentanglement the nature for the isolation of natural compounds that could modulate the ncRNAs and their respective targets is an applicable translational therapeutic ***,this study aimed to targeting the chief immune suppressive cytokines at the TME(TNF-αand IL-10)via ncRNAs and to examine the effects of Rosemary aerial parts extract on the expression levels of these ncRNAs in *** revealed miR-17-5p as a dual regulator of TNF-αand ***,an intricate interaction has been shown between miR-17-5p and the oncogenic lncRNAs:MALAT1 and *** down of MALAT1 and/or H19 caused an induction in miR-17-5p and reduction in TNF-αand IL-10 expression ***-17-5p was found to be down-regulated,while TNF-α,IL-10,MALAT1 and H19 were up-regulated in BC *** expression of miR-17-5p in MDA-MB-231 cells reduced TNF-α,IL-10,MALAT1 and H19 expression levels,as well as several BC *** a translational approach,ursolic acid(UA)isolated from rosemary induced the expression of miR-17-5p,MALAT1 and decreased H19 expression *** conclusion,this study suggests miR-17-5p as a tumor suppressor and an immune-activator miRNA in BC through tuning up the immunological targets TNF-α,IL-10 at the TME and the oncological mediators MALAT1 and H19 lncRNAs.

关键词： Breast cancer Tumor microenvironment Cytokines TNF-α IL-10 miR-17-5p MALAT1 H19 lncRNAs miRNA Ursolic acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of Aging on the Toughness of Austenitic and Duplex Stainless Steel Weldments

引用

Journal of Materials Science & Technology 2010年第9期26卷 810-816页

作者： Omyma Hassan Ibrahim Ibrahim soliman Ibrahim Tarek Ahmed Fouad Khalifa Metallurgy Dept. Nuclear Research CentreAtomic Energy Authority(Egypt) Nuclear Safety Centre Atomic Energy Authority(Egypt) Shoubra Faculty of Engineering Benha University

In the present study,the effect of aging heat treatment at 650,750,and 850？C on the impact toughness of 316L austenitic stainless steel,2205 duplex stainless steel and their weldments has been *** process was conducted using the TIG（tungsten inert gas） welding *** impact testing,at room temperature,was employed to determine the effect of aging treatment on the impact properties of investigated *** treatment resulted in degradation in the impact toughness as demonstrated by the reduction in the impact fracture energy and deformation parameters（strain hardening capacity,fracture deffection,and crack initiation and propagation energy）.The degree of embrittlement was more noticeable in duplex stainless steel parent and weld-metal than in 316L stainless steel and became greater with the increase of aging *** degradation in impact toughness was discussed in relation to the observed precipitation of the intermetallic sigma phase in the microstructure of the stainless steel weldments and the corresponding fracture surface morphology.

关键词： Austenitic and duplex stainless steels Aging Instrumented impact Toughness

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Glycated Hemoglobin HbA1c:Permittivity Experimental Applications with Some Mathematical Concepts,Temperature and Frequency Variations

引用

Journal of Renewable Materials 2022年第9期10卷 2335-2354页

作者： soliman Abdalla Sherif Kandil Waleed El-Shirbeeny Fatma Bahabri Department of Physics Faculty of ScienceKing Abdulaziz UniversityJeddahSaudi Arabia Department of Materials Science Institute of Graduate Studies and ResearchAlexandria UniversityAlexandriaEgypt Department of Physics Faculty of ScienceJeddah UniversityJeddahSaudi Arabia

Diabetes disorder turns smoothly to be a global epidemic disorder and the glycated hemoglobin(HbA1c)starts to be an efficient marker of *** dielectric spectroscopy on different human normal-and diabetic-blood samples is used to characterize and to estimate the HbA1c concentration.“dc-”and ac-measurement of the complex conductivity in the temperature range from 280 K up to 320 K,and in the frequency range from one Hz up to 32 MHz have been *** thermal activation energy,ΔEσ,of dc-electric conductivity lies in the range 95 meV<ΔEσ<115 meV;while the thermal activation energy,ΔEτ,of RBCs relaxation time is aboutΔEτ=140 *** experimental data have been modeled by a physical-model and good fittings have been found between calculated and experimental *** effective number of charges,nG,T,is estimated after Cole and Cole *** has found that nG,T increases with both temperature,T,and with the glycation rate *** increase may shed some light on an effective and possible way to treat(and to detect)diabetes disorders via eliminating the excess electric charges produced by glycation *** present work sheds the light on the possible combination of focused ultrasound with magnetic resonance imaging to study the dielectric-thermal variations of glycated-RBCs,which can lead to very precise and non-invasive monitoring of glycation concentration in vivo and in vitro via magnetic resonance-thermometry.

关键词： Glycated-hemoglobin rate thermal characterization red blood cells RBCs relaxation of RBCs dielectric constant mathematical model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Linearly and Quadratically Separable Classifiers Using Adaptive Approach

引用

Journal of Computer Science & Technology 2011年第5期26卷 908-918页

作者： Mohamed Abdel-Kawy Mohamed Ali soliman Rasha M.Abo-Bakr Department of Computer and Systems Engineering Faculty of EngineeringZagazig UniversityZagazigEgypt Departement of Mathematics Faculty of ScienceZagazig UniversityZagazigEgypt

This paper presents a fast adaptive iterative algorithm to solve linearly separable classification problems in R *** each iteration,a subset of the sampling data （n-points,where n is the number of features） is adaptively chosen and a hyperplane is constructed such that it separates the chosen n-points at a margin and best classifies the remaining *** classification problem is formulated and the details of the algorithm are ***,the algorithm is extended to solving quadratically separable classification *** basic idea is based on mapping the physical space to another larger one where the problem becomes linearly *** illustrations show that few iteration steps are sufficient for convergence when classes are linearly *** nonlinearly separable data,given a specified maximum number of iteration steps,the algorithm returns the best hyperplane that minimizes the number of misclassified points occurring through these *** with other machine learning algorithms on practical and benchmark datasets are also presented,showing the performance of the proposed algorithm.

关键词： linear classification quadratic classification iterative approach adaptive technique

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Coexisting tubular adenoma with a neuroendocrine carcinoma of colon allowing early surgical intervention and implicating a shared stem cell origin

引用

World Journal of Gastroenterology 2017年第6期23卷 1106-1112页

作者： Mahmoud L soliman Ashish Tiwari Qing Zhao Department of Pathology and Laboratory Medicine Boston University Medical Center Department of Gastroenterology Boston University Medical Center

High-grade colonic neuroendocrine carcinomas (NECs) are uncommon but extremely aggressive. Their co-existence with tubular adenoma (TA) has rarely been reported. We present a 68-year-old man who was found on routine colonoscopy to have multiple colorectal TAs and an ulcerated lesion in the ascending colon. Microscopically, a poorly-differentiated invasive carcinoma juxtaposed with a TA was identified. Differential diagnosis included a poorly-differentiated adenocarcinoma, medullary carcinoma, high-grade NEC and lymphoma. The immunohistochemical profile showed positive staining for keratins, synaptophysin and chromogranin but negative for LCA, CDX2, CK7, CK20, TTF-1 and PSA, supporting the NEC diagnosis. Upon subsequent laparoscopic right hemicolectomy, the tumor was identified as a 3.0 cm umbilicated and ulcerated mass with an adjacent TA. Both TA and NEC showed positive staining for β-catenin indicating a shared colonic origin. The mitotic counts (77/10 high power fields) and a high proliferation rate (75% by Ki-67) corroborated a high-grade stratification. Mutational analysis indicated a wild-type BRAF and KRAS with mismatch repair proficiency. The AJCC (7th edition) pathologic stage is pT3, pN0, pMx. The patient received adjuvant chemotherapy with cisplatin/etoposides for three cycles and will be followed up for a year to detect recurrence. In conclusion, the co-existence of TA with high grade-NEC in our case allowed early identification and intervention of the otherwise asymptomatic but aggressive tumor. In addition, the finding of a high-grade NEC within a large TA in this case suggests a link between the two lesions and could represent a shared stem cell origin.

关键词： Neuroendocrine carcinoma Tubular adenoma Colorectal Colocalization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fano Factor in Strained Graphene Nanoribbon Nanodevices

引用

Chinese Physics Letters 2017年第11期34卷 114-118页

作者： Walid soliman Mina D.Asham Adel H.Phillips Faculty of Engineering Benha UniversityBenhaEgypt Faculty of Engineering AinShams UniversityCairoEgypt

We investigate the Fano factor in a strained armchair and zigzag graphene nanoribbon nanodevice under the effect of ac field in a wide range of frequencies at different temperatures （10？K–70？K）. This nanodevice is modeled as follows： a graphene nanoribbon is connected to two metallic leads. These two metallic leads operate as a source and a drain. The conducting substance is the gate electrode in this three-terminal nanodevice. Another metallic gate is used to govern the electrostatics and the switching of the graphene nanoribbon channel. The substances at the graphene nanoribbon/metal contact are controlled by the back gate. The photon-assisted tunneling probability is deduced by solving the Dirac eigenvalue differential equation in which the Fano factor is expressed in terms of this tunneling probability. The results show that for the investigated nanodevice, the Fano factor decreases as the frequency of the induced ac field increases, while it increases as the temperature increases. In general, the Fano factors for both strained armchair and zigzag graphene nanoribbons are different. This is due to the effect of the uniaxial strain. It is shown that the band structure parameters of graphene nanoribbons at the energy gap, the C–C bond length, the hopping integral, the Fermi energy and the width are modulated by uniaxial strain. This research gives us a promise of the present nanodevice being used for digital nanoelectronics and sensors.

关键词： Fano Factor in Strained Graphene Nanoribbon Nanodevices

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Petrogenesis,Geodynamics and Radioactivity of the Granitic Rocks of the Nugrus Weakness Zone,South Eastern Desert,Egypt

引用

Acta Geologica Sinica(English Edition) 2021年第4期95卷 1183-1198页

作者： soliman ABU ELATTA Abdallah Mahmoud Gehad M.R.MANSOUR Nuclear Materials Authority CairoEgypt.P.O.Box 530 El Maadi

The studied granitic bodies belong to the south Eastern Desert of *** extend in a NNW–SSE trend along the same strike of the Nugrus weakness zone by which they are structurally *** rocks are composed of biotite and biotite-muscovite monzogranites to ***,a higher abundance of Ba and Rb in biotite granites with a relatively low abundance in biotite-muscovite granites as well as the diversity of Th,U,Nb,Ta,Zr,and REE reflects their origin from different sources and geodynamic *** biotite granites are predominantly metaluminous to low peraluminous whereas the biotite-muscovite granites have a peraluminous *** enrichment at the expense of calcium in these rocks reflects a derivation from crustal sources by partial melting in the presence of a volatile *** investigation showed high abundances of U(up to 38 ppm)and Th(up to 26 ppm)in biotite-muscovite granites relative to biotite granites(up to 5 ppm U and 18 ppm Th).Radioactive anomalies furthermore have been recorded in parts of biotite-muscovite granites that were affected by the faults(up to 116 ppm eU and 97 ppm eTh).Consequently,biotite-muscovite granites form a potentially fertile source for uranium mineralization.

关键词： partial melting biotite-muscovite granites peraluminous geodynamic radioactivity Nugrus

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ciprofloxacin adsorption from aqueous solution onto chemically prepared carbon from date palm leaflets

引用

Journal of Environmental Sciences 2012年第9期24卷 1579-1586页

作者： El-Said Ibrahim El-Shafey Haider Al-Lawati Asmaa.soliman Al-Sumri Department of Chemistry College of ScienceSultan Qaboos UniversityP.O.Box 36-Al-Khodh 123MuscatOman

A chemically prepared carbon was synthesized from date palm leaflets via sulphuric acid carbonization at 160℃. Adsorption of ciprofloxacin （CIP） from aqueous solution was investigated in terms of time, pH, concentration, temperature and adsorbent status （wet and dry）. The equilibrium time was found to be 48 hr. The adsorption rate was enhanced by raising the temperature for both adsorbents, with adsorption data fitting a pseudo second-order model well. The activation energy, Ea, was found to be 17 kJ/mol, indicating a diffusion-controlled, physical adsorption process. The maximum adsorption was found at initial pH 6. The wet adsorbent showed faster removal with higher uptake than the dry adsorbent, with increased performance as temperature increased （25--45℃）. The equilibrium data were found to fit the Langmuir model better than the Freundlich model. The thermodynamic parameters showed that the adsorption process is spontaneous and endothermic. The adsorption mechanism is mainly related to cation exchange and hydrogen bonding.

关键词： ciprofloxacin carbon adsorption palm leaflets

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Simultaneous effects of magnetic field and space porosity on compressible Maxwell fluid transport induced by a surface acoustic wave in a microchannel

引用

Chinese Physics B 2013年第12期22卷 323-332页

作者： Khaled S.Mekheimer soliman R.Komy Sara I.Abdelsalam Mathematics & Statistics Department Faculty of Science Taif University Department of Mathematics Faculty of Science (Men) Al-Azhar University Department of Mathematics Faculty of Science Helwan University Basic Science Department Faculty of Engineering The British University in Egypt

Peristaltic motion induced by a surface acoustic wave of a viscous, compressible and electrically conducting Maxwell fluid in a confined parallel-plane microchannel through a porous medium is investigated in the presence of a constant magnetic field. The slip velocity is considered and the problem is discussed only for the free pumping case. A perturbation technique is employed to analyze the problem in terms of a small amplitude ratio. The phenomenon of a “backward flow” is found to exist in the center and at the boundaries of the channel. In the second order approximation, the net axial velocity is calculated for various values of the fluid parameters. Finally, the effects of the parameters of interest on the mean axial velocity, the reversal flow, and the perturbation function are discussed and shown graphically. We find that in the non-Newtonian regime, there is a possibility of a fluid flow in the direction opposite to the propagation of the traveling wave. This work is the most general model of peristalsis created to date with wide-ranging applications in biological, geophysical and industrial fluid dynamics.

关键词： peristaltic flow Maxwell fluid porous medium slip flow microchannel

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：