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History and evolution of the use of oral mucosa for urethral reconstruction

Asian Journal of Urology 2017年第2期4卷 96-101页

作者： Guido Barbagli sofia balo Francesco Montorsi Salvatore Sansalone Massimo Lazzeri Centro Chirurgico Toscano ArezzoItaly Division of Oncology/Unit of Urology IRCCS Ospedale San RaffaeleMilanItaly Department of Experimental Medicine and Surgery University of Tor VergataRomeItaly Department of Urology Istituto Clinico Humanitas IRCCSClinical and Research HospitalRozzanoItaly

We report here the history and evolution of the use of oral mucosa in reconstructive urethral surgery since it was first used for urethroplasty in *** that time,many authors have contributed to develop,improve and popularize the use of oral mucosa as a substitute *** urologists should be considered pioneers on the use of oral mucosa as they used it to repair primary and failed *** use of oral mucosa to repair penile and bulbar urethral strictures was described,for the first time,in *** evolutions in the technique for harvesting oral mucosa from the cheek were reported in ***,oral mucosa is considered the gold standard material for any type of anterior urethroplasty in a one-or two-stage repair due to its biological and structural characteristics that make it a highly versatile that is adaptable to any environment required by the reconstructive urethral *** the future approaches,tissue engineering techniques will provide patients with new materials originating from the oral epithelial mucosal cells,which are cultured and expanded into a ***,the path to reach this ambitious objective is still long and many difficulties must be overcome along the way.

关键词： Oral mucosa Cheek Urethra Urethroplasty Tissue engineering Reconstructive urology

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