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Supplementation of vitamin E or.a botanical extr.ct as antioxidants to impr.ve gr.wth per.or.ance and health of gr.wing pigs housed under.ther.oneutr.l or.heat-str.ssed conditions

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Jour.al of Animal Science and Biotechnology 2024年第3期15卷 1101-1118页

作者： Ysenia V.Silva‑Guillen Consuelo Ar.llano jeffrey Wieger. r.Dean Boyd Gabr.ela E.Mar.inez Er.c van Heugten Depar.ment of Animal Science North Carolina State UniversityRaleighNC 27695USA Depar.ment of Statistics North Carolina State UniversityRaleighNC 27695USA Depar.ment of Animal Science Texas A&M UniversityCollege StationTX 77843USA Animal Nutr.tion r.sear.h LLCAlvatonKY 42122USA.

Backgr.und Heat str.ss has sever. negative consequences on per.or.ance and health of pigs,leading to significant economic *** objective of this study was to investigate the effects of supplemental vitamin E and a botanical extr.ct in feed or.dr.nking water.on gr.wth per.or.ance,intestinal health,and oxidative and immune status in gr.w-ing pigs housed under.heat str.ss *** Duplicate exper.ments wer. conducted,each using 64 cr.ssbr.d pigs with an initial body weight of 50.7±3.8 and 43.9±3.6 kg and age of 13-week and 12-week,***(n=128)wer. housed individually and assigned within weight blocks and sex to a 2×4 factor.al ar.angement consisting of 2 envir.nments(ther.o-neutr.l(21.2℃)or.heat-str.ssed(30.9℃))and 4 supplementation tr.atments(contr.l diet;contr.l+100 IU/L of D-α-tocopher.l in water.contr.l+200 IU/kg of DL-α-tocopher.l-acetate in feed;or.contr.l+400 mg/kg of a botanical extr.ct in feed).r.sults Heat str.ss for.28 d r.duced(P≤0.001)final body weight,aver.ge daily gain,and aver.ge daily feed intake(-7.4 kg,-26.7%,and-25.4%,r.spectively)but no effects of supplementation wer. detected(P>0.05).Ser.m vitamin E incr.ased(Pr.and in feed(1.64 vs.3.59 and 1.64 vs.3.24),but not for.the botanical extr.ct(1.64 vs.1.67 mg/kg)and was gr.ater.when supplemented in water.***(P=0.002).Liver.vitamin E incr.ased(Pr.3.9 vs.31.8)and feed(3.9 vs.18.0),but not with the botanical extr.ct(3.9 vs.4.9 mg/kg).Ser.m malondialdehyde was r.duced with heat str.ss on d 2,but incr.ased on d 28(inter.ction,Pr.ater.Pr.antioxidant supplementation compar.d to *** pr.lifer.tion was r.duced(P=0.037)in the jejunum under.heat str.ss,but incr.ased in the ileum when vitamin E was supplemented in feed and water.under.heat str.ss(inter.ction,P=0.04).Tumor.necr.sis factor.αin jejunum and ileum mucosa decr.ased by heat str.ss(Pr.

关键词： Botanical extr.ct Gr.wing pigs Heat str.ss Immune status Oxidative status Tocopher.l Water

Coupled Inver.ion of Pr.ssur. and Tiltmeter.Data for.Mapping Hydr.ulic Fr.ctur. Geometr.

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Acta Mechanica Solida Sinica 2024年第3期37卷 396-405页

作者： Zuor.ng Chen Xiaofang Jiang Zhejun Pan r.ber. G.jeffrey National Key Labor.tor. of Continental Shale Oil Northeast Petroleum UniversityDaqing163318China SCT Oper.tion Pty.Ltd. PO Box 824WollongongNSW2520Australia

Pr.ssur. and tilt data ar. jointly inver.ed to simultaneously map the or.entation and dimensions of a hydr.ulic *** defor.ation induced by a fr.ctur. under.inter.al pr.ssur. is modeled using the distr.buted dislocation *** planar.fr.ctur. is r.pr.sented by four.quar.er.ellipses,joined at the center.and shar.ng *** configur.tion pr.vides a str.ightfor.ar. model for.char.cter.zing asymmetr.c fr.ctur. *** inver.e pr.blem of mapping the fr.ctur. geometr. is for.ulated using the Bayesian pr.babilistic method,combining the a pr.or. infor.ation on the fr.ctur. model with updated infor.ation fr.m pr.ssur. and tilt *** the nonlinear.inver.e pr.blem is achieved by pseudo-r.ndomly sampling the poster.or.pr.bability distr.bution thr.ugh the Mar.ov chain Monte Car.o *** r.sulting poster.or.pr.bability distr.bution is then explor.d to assess uncer.ainty,r.solution,and cor.elation between model *** exper.ments ar. conducted to ver.fy the accur.cy and validity of the pr.posed analysis method in mapping the fr.ctur. geometr. using synthetic pr.ssur. and tilt data.

关键词： Hydr.ulic fr.ctur. mapping Coupled inver.ion Tilt Tr.ating pr.ssur.

Thr.e cases of uncommon medication-associated osteonecr.sis of tempor.l bone

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Wor.d Jour.al of Otor.inolar.ngology-Head and Neck Sur.er. 2024年第3期10卷 237-240页

作者： Hunter.VanDolah Jason r.Cr.ssley H.jeffrey Kim Geor.etown Univer.ity School of Medicine Washington DCUSA Depar.ment of Otolar.ngology–Head and Neck Sur.er. MedStar Georgetown University HospitalWashington DCUSA

Intr.duction:Medication-r.lated osteonecr.sis of the tempor.l bone is r.r. and has been r.por.ed to be associated with the use of anti-r.sor.tive and biologic ***,we pr.sent the fir.t case of tyr.sine-kinase inhibitor.r.lated exter.al auditor. canal(EAC)osteonecr.sis as well as two cases r.lated to anti-r.sor.tive ***:A r.tr.spective case ***:Case one:an 84-year.old female pr.sented with chr.nic otitis exter.a and osteonecr.sis of EACs *** had a histor. of osteopor.sis tr.ated with denosumab and r.sedr.nic *** successfully under.ent left EAC r.constr.ction using an infer.or.y-based pedicle per.osteal flap while the r.ght ear.canal was managed *** two:a 69-year.old male pr.sented with osteonecr.sis of the r.ght *** had a histor. of osteopor.sis tr.ated with alendr.nic acid and zoledr.nic *** osteonecr.sis is conser.atively managed with local debr.dement and antibiotic *** thr.e:a 60-year.old male pr.sented with osteonecr.sis of the r.ght infer.or.*** had a histor. of chr.nic myelogenous leukemia tr.ated with a tyr.sine-kinase inhibitor.*** failing conser.ative ther.py,he under.ent r.ght ear.canal r.constr.ction using a per.osteal vascular.pedicle flap without complication and exper.enced complete r.solution to his ***:Anti-r.sor.tive agents and/or.tyr.sine kinase inhibitor. may lead to dysr.gulation of bone r.modeling and r.sult in r.r. cases of tempor.l bone *** a local debr.dement and antibiotic ther.py fail,definitive sur.ical excision of necr.tic bone with subsequent r.constr.ction of the EAC may offer.patients a possible r.solution in symptoms.

关键词： bisphosphonates denosumab exter.al auditor. canal imatinib medication-r.lated osteonecr.sis osteonecr.sis tempor.l bone tyr.sine-kinase Inhibitor.

New insights on the high-cor.osion r.sistance of UHP Mg-Ge alloys tested in a simulated physiological envir.nment

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Jour.al of Magnesium and Alloys 2024年第3期12卷 1026-1044页

作者： Ting Liu Xingr.i Chen jeffrey Venezuela Yuan Wang Zhiming Shi Wenyi Chen Matthew Dar.usch Centr. for.Advanced Mater.als Pr.cessing and Manufactur.ng(AMPAM) School of Mechanical and Mining Engineeringthe University of QueenslandBrisbaneQLD 4072Australia CSIr. Miner.l r.sour.es 1 Technology CourtPullenvaleQLD 4069Australia

UHP Mg-Ge alloys was r.cently found to pr.vide excellent cor.osion *** paper.pr.vides new insights on the mechanism of impr.ved cor.osion r.sistance of UHP Mg-Ge alloys in Hanks’*** studied UHP Mg-0.5Ge and UHP Mg-1Ge alloys showed super.or.cor.osion r.sistance compar.d to UHP Mg and WE43,with the Mg-1Ge exhibiting the best cor.osion *** exceptional cor.osion r.sistance of the UHP alloy is attr.buted to(i)Mg_(2)Ge’s ability to suppr.ss cathodic kinetics,(ii)Ge’s capability to acceler.te the for.ation of a highly passive layer.and the(iii)low amounts of cor.osion-acceler.ting impur.ties.

关键词： UHP Mg-Ge alloy Cathodic kinetics suppr.ssion Biodegr.dable metals In vitr. cor.osion Magnesium cor.osion.

Back to the dr.wing boar.:Over.iew of the next gener.tion of combination ther.py for.inflammator. bowel disease

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Wor.d Jour.al of Gastr.enter.logy 2024年第25期30卷 3182-3184页

作者： jeffrey A Lowell Michael J Far.er.Keith Sultan Depar.ment of Medicine Zucker School of Medicine at HofstraNorth Shore University Hospital-Long Island Jewish Medical CenterManhassetNY 11030United States Pr.clinical Studies New York Institute of Technology College of Osteopathic MedicineGlen HeadNY 11545United States Division of Gastr.enter.logy Northwell HealthNorth Shore University Hospital and Long Island Jewish Medical CenterGreat NeckNY 10021United States

Inflammator. bowel disease(IBD)is enter.ng a potentially new er. of combined *** et al pr.vide an insightful r.view of the cur.ent state of combination ther.py,with a focus on the use of a combined biologic and immunomodulator.as well as emer.ing data on the futur. potential of dual-biologic ther.py(DBT).While cur.ent evidence for.DBT is limited,encour.ging safety pr.files and ongoing tr.als suggest a br.ghter.futur. for.this *** impor.ance of contr.lled tr.als should be str.ssed in establishing new tr.atment *** pr.spective r.ndomized tr.als of DBT and per.aps futur. combinations of biologics and small molecule ther.pies will hopefully guide the next gener.tion of IBD car..

关键词： Inflammator. bowel disease Biologics Immunomodulator. Dual-ther.py Combination ther.py

The syner.istic inter.lay of ar.ificial intelligence and digital twin in envir.nmentally planning sustainable smar. cities:A compr.hensive systematic r.view

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Envir.nmental Science and Ecotechnology 2024年第4期20卷 79-104页

作者： Simon Elias Bibr. jeffrey Huang Senthil Kumar.Jagatheesaper.mal John Kr.gstie Swiss Feder.l Institute of Technology Lausanne(EPFL) Institute of Computer and Communication Sciences(IINFCOM)School of ArchitectureCivil and Environmental Engineering(ENAC)Media and Design Laboratory(LDM)1015LausanneSwitzerland Depar.ment of Electr.nics&Communication Engineer.ng Mepco Schlenk Engineering CollegeSivakasi626005TamilnaduIndia Depar.ment of Computer.Science Norwegian University of Science and Technology(NTNU)TrondheimNorway

The dynamic landscape of sustainable smar. cities is witnessing a significant tr.nsfor.ation due to the integr.tion of emer.ing computational technologies and innovative *** advancements ar. r.shaping data-dr.ven planning str.tegies,pr.ctices,and appr.aches,ther.by facilitating the achievement of envir.nmental sustainability *** tr.nsfor.ative wave signals a fundamental shift d mar.ed by the syner.istic oper.tion of ar.ificial intelligence(AI),ar.ificial intelligence of things(AIoT),and ur.an digital twin(UDT)*** pr.vious r.sear.h has lar.ely explor.d ur.an AI,ur.an AIoT,and UDT in isolation,a significant knowledge gap exists r.gar.ing their.syner.istic inter.lay,collabor.tive integr.tion,and collective impact on data-dr.ven envir.nmental planning in the dynamic context of sustainable smar. *** addr.ss this gap,this study conducts a compr.hensive systematic r.view to uncover.the intr.cate inter.ctions among these inter.onnected technologies,models,and domains while elucidating the nuanced dynamics and untapped syner.ies in the complex ecosystem of sustainable smar. *** to this study ar. four.guiding r.sear.h questions:*** theor.tical and pr.ctical foundations under.in the conver.ence of AI,AIoT,UDT,data-dr.ven planning,and envir.nmental sustainability in sustainable smar. cities,and how can these components be synthesized into a novel compr.hensive fr.mewor.?*** does integr.ting AI and AIoT r.shape the landscape of datadr.ven planning to impr.ve the envir.nmental per.or.ance of sustainable smar. cities?*** can AI and AIoT augment the capabilities of UDT to enhance data-dr.ven envir.nmental planning pr.cesses in sustainable smar. cities?*** challenges and bar.ier. ar.se in integr.ting and implementing AI,AIoT,and UDT in data-dr.ven envir.nmental ur.an planning,and what str.tegies can be devised to sur.ount or.mitigate them?Methodologically,this study involves a r.gor.us analysis and synthesis of studies publis

关键词： Sustainable smar. cities Ar.ificial intelligence Ar.ificial intelligence of things Ur.an digital twin Data-dr.ven ur.an planning Envir.nmental planning Envir.nmental sustainability

Nano-enhanced solid-state hydr.gen stor.ge:Balancing discover. and pr.gmatism for.futur. ener.y solutions

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Nano r.sear.h 2024年第10期17卷 8729-8753页

作者： Chaochao Dun Xinyi Wang Linfeng Chen Sichi Li Hanna M.Br.unig jeffrey J.Ur.an The Molecular.Foundr. Lawrence Berkeley National Laboratory BerkeleyBerkeleyCA 94720USA Ener.y Analysis and Envir.nmental Impacts Division Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA Lawr.nce Liver.or. National Labor.tor. LivermoreCA 94550USA

Nanomater.als have r.volutionized the batter. industr. by enhancing ener.y stor.ge capacities and char.ing speeds,and their.application in hydr.gen(H_(2))stor.ge likewise holds str.ng potential,though with distinct challenges and mechanisms.H_(2) is a cr.cial futur. zer.-car.on ener.y vector.given its high gr.vimetr.c ener.y density,which far.exceeds that of liquid ***,its low volumetr.c ener.y density in gaseous for. cur.ently r.quir.s stor.ge under.high pr.ssur. or.at low *** r.view cr.tically examines the cur.ent and pr.spective landscapes of solid-state H_(2) stor.ge technologies,with a focus on pr.gmatic integr.tion of advanced mater.als such as metal-or.anic fr.mewor.s(MOFs),magnesium-based hybr.ds,and novel sor.ents into futur. ener.y *** mater.als,enhanced by nanotechnology,could significantly impr.ve the efficiency and capacity of H_(2) stor.ge systems by optimizing H_(2) adsor.tion at the nanoscale and impr.ving the kinetics of H_(2) uptake and *** discuss var.ous H_(2) stor.ge mechanisms—physisor.tion,chemisor.tion,and the Kubas inter.ction—analyzing their.impact on the ener.y efficiency and scalability of stor.ge *** r.view also addr.sses the potential of“smar. MOFs”,single-atom catalyst-doped metal hydr.des,MXenes and entr.py-dr.ven alloys to enhance the per.or.ance and br.aden the application r.nge of H_(2) stor.ge systems,str.ssing the need for.innovative mater.als and system integr.tion to satisfy futur. ener.y ***-thr.ughput scr.ening,combined with machine lear.ing algor.thms,is noted as a pr.mising appr.ach to identify patter.s and pr.dict the behavior.of novel mater.als under.var.ous conditions,significantly r.ducing the time and cost associated with exper.mental *** closing,we discuss the incr.asing involvement of var.ous companies in solid-state H_(2) stor.ge,par.icular.y in pr.totype vehicles,fr.m a techno-economic *** for.ar.-looking per.pective under.cor.s t

关键词： nanomater.als nanotechnology solid-state H_(2)stor.ge techno-economic analysis model-dr.ven mater.al development pr.cesses

Advances in gr.und heat exchanger. for.space heating and cooling:r.view and per.pectives

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Ener.y and Built Envir.nment 2024年第2期5卷 255-269页

作者： Ping Cui Weibo Yang Wenke Zhang Ke Zhu jeffrey D.Spitler.Mingzhi Yu School of Ther.al Engineer.ng Shandong Jianzhu UniversityJinanShandong 250101China College of Electr.cal Energy and Power EngineeringYangzhou UniversityYangzhouJiangsu 225127China Depar.ment of Mechanical Engineer.ng Oklahoma State UniversityStillwaterOKUSA

As a r.newable ener.y sour.e,geother.al ener.y has been widely used to pr.vide space heating and cooling for.*** ther.al per.or.ance of gr.und heat exchanger.GHE)is significant for.the oper.ting efficiency of the gr.und sour.e heat pump(GSHP)*** paper.pr.sents a compr.hensive r.view of developments and advances of thr.e kinds of GHE,including ver.ical bor.hole GHE(VBGHE),Pile GHE(PGHE),and deep bor.hole GHE(DBGHE)which ar. cur.ently popular.in lar.er.GSHP ***,analytical models pr.posed to ana-lyze heat tr.nsfer.pr.cess of VBGHE with differ.nt geological conditions ar. summar.zed,such as homogenous or.heter.geneous gr.und,with or.without gr.undwater.*** and shor.-time step models and measur.s to impr.ve GHE ther.al per.or.ance ar. also ***,a summar. of r.sear.h advances in PGHE is pr.vided,which includes the heat tr.nsfer.models of PGHE,the effects of geometr.c str.ctur.,oper.ation modes,pile spacing,use of phase change mater.al(PCM),ther.al pr.per.ies of PCM,ther.o-mechanical behavior.and/or.ther.al per.or.ance of *** effects of gr.undwater.flow dir.ction and velocity on PGHE ar. also summar.zed in ***,models of thr.e kinds of DBGHEs,i.e.,deep coaxial GHE(DCGHE),deep U-bend GHE(DUGHE)and super.long gr.vity heat pipe(SLGHP),ar. *** physical bases of the dif-fer.nt analytical models ar. elabor.ted and also their.advantages and disadvantages ar. *** in numer.cal modelling and impr.ving numer.cal model calculation speed of DCBHE,DCBHE ar.ay,and DUBHE ar. *** r.view pr.vides a meaningful r.fer.nce for.the fur.her.study of GHEs.

关键词： Ver.ical bor.hole gr.und heat exchanger Pile gr.und heat exchanger Deep bor.hole gr.und heat exchanger Modelling

Pr.dictor. of sur.ival in autoimmune liver.disease over.ap syndr.mes

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Wor.d Jour.al of Hepatology 2024年第9期16卷 1269-1277页

作者： Dujinthan Jayabalan Yi Huang Luis Calzadilla-Ber.ot Malik Janjua Bastiaan de Boer.John Joseph Wendy Cheng Simon Hazeldine Br.ohny W smith Ger.y C MacQuillan Michael C Wallace Geor.e Gar.s Leon A Adams Gar. P jeffrey Medical School University of Western AustraliaNed-lands 6009Western AustraliaAustralia Depar.ment of Hepatology Sir Charles Gairdner HospitalNedlands 6009Western AustraliaAustralia Depar.ment of Anatomical Pathology PathWest Laboratory MedicineNedlands 6009Western AustraliaAustralia Depar.ment of Gastr.enter.logy and Hepatology Royal Perth HospitalPerth 6000Western AustraliaAustralia Depar.ment of Gastr.enter.logy and Hepatology Fiona Stanley HospitalMurdoch 6150Western AustraliaAustralia Medical School University of Western AustraliaNedl-ands 6009Western AustraliaAustralia

BACKGr.UND Sur.ival in patients with autoimmune liver.disease over.ap syndr.mes(AILDOS)compar.d to those with single autoimmune liver.disease is *** To investigate the sur.ival of patients with AILDOS and assess the accur.cy of non-invasive ser.m models for.pr.dicting liver.r.lated *** Patients with AILDOS wer. defined as either.autoimmune hepatitis and pr.mar. biliar. cholangitis over.ap(AIH-PBC)or.autoimmune hepatitis and pr.mar. scler.sing cholangitis over.ap(AIH-PSC)and wer. identified fr.m thr.e ter.iar. centr.s for.this cohor. ***-r.lated death or.tr.nsplantation(liver.r.lated mor.ality)was deter.ined using a population-based data linkage *** scor.s for.liver.r.lated death wer. compar.d for.accur.cy[including liver.outcome scor.(LOS),Hepascor.,Mayo Scor.,model for.end-stage liver.disease(MELD)scor. and MELD incor.or.ted with ser.m sodium(MELD-Na)scor.].r.SULTS Twenty-two AILDOS patients wer. followed for.a median of 3.1 year.(r.nge,0.35-7.7).Four.een wer. female,the median age was 46.7 year.(r.nge,17.8 to 82.1)and median Hepascor. was 1(r.nge,0.07-1).At five year. post enr.lment,57%of patients r.mained fr.e fr.m liver.r.lated mor.ality(74%AIH-PBC,27%AIH-PSC).Ther. was no significant differ.nce in sur.ival between AIH-PBC and *** was a significant pr.dictor.of liver.r.lated mor.ality(Pr.minated liver.r.lated mor.ality in AIH-PBC patients(P=0.012,log-r.nk test,100%sensitivity,77.8%specificity)(Har.ell's C-statistic 0.867).The MELD scor.,MELD-Na scor. and Mayo Scor. wer. not pr.dictive of liver.r.lated mor.ality in any *** Sur.ival in the r.r.,AILDOS is *** cur.ent study suppor.s the LOS as a pr.dictor.of liver.r.lated mor.ality in AIH-PBC *** tr.als investigating pr.dictor. of sur.ival in AILDOS ar. r.quir.d.

关键词： Autoimmune liver.disease over.ap syndr.mes Liver.outcome scor. Liver.r.lated death Hepascor. Autoimmune hepatitis Pr.mar. biliar. cholangitis Pr.mar. scler.sing cholangitis