检索结果-南通市图书馆

Hepatitis C virus genotypes in Serbia and Montenegro: The prevalence and clinical signifi cance

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第3期13卷 355-360页

作者： Neda Svirtlih Dragan Delic Jasmina Simonovic Djordje Jevtovic Ljubisa Dokic Eleonora Gvozdenovic Ivan Boricic Dragica Terzic sladjana Pavic Gorana Neskovic Sonja Zerjav Vladimir Urban Institute for Infectious Diseases Clinical Centre of Serbia Belgrade Serbia Institute for Pathology Medical Faculty University of Belgrade Serbia Clinical Centre of Podgorica Montenegro General Hospital Uzice Serbia Institute for Nuclear Sciences Vinca Serbia Medical Faculty University of Belgrade Serbia

AIM： To investigate the prevalence of hepatitis C virus （HCV） genotypes in Serbia and Montenegro and their influence on some clinical characteristics in patients with chronic HCV infection. METHODS： A total of 164 patients was investigated. Complete history, route of infection, assessment of alcohol consumption, an abdominal ultrasound, standard biochemical tests and liver biopsy were done. Gene sequencing of 5＇ NTR type-specific PCR or commercial kits was performed for HCV genotyping and subtyping. The SPSS for Windows （version 10.0） was used for univariate regression analysis with further multivariate analysis. RESULTS： The genotypes 1, 2, 3, 4, 1b3a and 1b4 were present in 57.9%, 3.7%, 23.2%, 6.7%, 6.7% and 1.8% of the patients, respectively. The genotype 1 （mainly the subtype 1b） was found to be independent of age in subjects older than 40 years, high viral load, more severe necro-inflammatory activity, advanced stage of fibrosis, and absence of intravenous drug abuse. The genotype 3a was associated with intravenous drug abuse and the age below 40. Multivariate analysis demonstrated age over 40 and intravenous drug abuse as the positive predictive factors for the genotypes lb and 3a, respectively.CONCLUSION： In Serbia and Montenegro, the genotypes 1b and 3a predominate in patients with chronic HCV infection. The subtype lb is characteristic of older patients, while the genotype 3a is common in drug abusers. Association of the subtype lb with advanced liver disease, higher viral load and histological activity suggests earlier infection with this genotype and eventually its increased pathogenicity.

关键词： Hepatitis C virus Genotypes Prevalence Serbia Montenegro

Nitric oxide and tumour necrosis factor alpha in the process of pseudoexfoliation glaucoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2016年第8期9卷 1138-1142页

作者： Tatjana S.Sarenac Vulovic sladjana M.Pavlovic Vladimir LJ.Jakovljevic Katarina B.Janicijevic Nemanja S.Zdravkovic Department of Ophthalmology Clinical Center Kragujevac Center for Molecular Medicine and Stem Cell Research Faculty of Medical Sciences University of Kragujevac Department of Physiology Faculty of Medical SciencesUniversity of Kragujevac Faculty of Medical Sciences University of Kragujevac

AIMTo establish the role of nitric oxide (NO), ascorbic acid and tumour necrosis factor-α (TNF-α) in the pathogenesis of pseudoexfoliation glaucoma (XFG).METHODSOur study included 120 patients who were referred for cataract surgery. All patients were divided into four groups according to clinical findings: XFG, early and late pseudoexfoliation syndrome (XFS), and cataract (without pseudoexfoliation). Serum and aqueous humour levels of the ascorbic acid, NO and TNF-α were measured. The concentrations of the ascorbic acid and NO were measured by an appropriate spectrophotometric method. Enzyme-linked immunosorbent assay (ELISA) was used to determine TNF-α *** humour concentration of ascorbic acid was significantly lower in patients with late XFS (0.61±0.11 mmol/L) and XFG (0.48±0.15 mmol/L) compared to patients with early XFS (0.9±0.15 mmol/L) and cataract (1.16±0.22 mmol/L), while there was no difference in serum concentration in all examined groups. Aqueous humour concentration of NO was significantly higher in patients with XFG (77.7±11.4 µmol/L) compared to patients with early XFS (50.27±9.34 µmol/L) and cataract (49.77±7.1 µmol/L), while serum concentration was increased in the early stage of XFS (73.26±8.29 µmol/L). Aqueous humour level of proinflammatory cytokine TNF-α was increased in patients with XFS (early 460.04±18.32 pg/mL; late 502.42±53.23 pg/mL) and XFG (510.34±43.07 pg/mL), while there was no difference in serum level in all examined groups of *** ascorbic acid and elevated NO and inflammation related cytokine TNF-α level in aqueous humour of the patients with developed XFG suggest that oxidative stress induces local inflammation.

关键词： ascorbic acid nitric oxide pseudoexfoliation tumour necrosis factor alpha

Monitoring Re-Suspension and Transport of Dioxin Contaminated Sediment to Evaluate the Recovery of a Shallow Urban Creek Post Sediment Remediation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2016年第3期7卷 453-466页

作者： Lisa Richman Liad Haimovici Terry Kolic sladjana Besevic Eric Reiner Ministry of the Environment and Climate Change Etobicoke Canada

Pringle Creek, identified as the source of dioxin/furan (PCDD/F) contamination to a Lake Ontario harbour was remediated in 2008. Surface sediment collected in 2013 near the floodplain remediation was no longer contaminated (∑17PCDD\Fs 17PCDD\Fs 2900 pg/g dw). Nevertheless, sediment ∑17PCDD/F concentrations were lower in 2013 than pre-remediation suggesting that cleaner sediment was being deposited in the creek. Core data confirmed the decrease in sediment contamination through time since the most contaminated sediment was buried. Prior to the development of a remediation strategy for the harbour, the transport of bed-load and suspended sediment contaminated with PCDD/F was assessed. The challenge was the shallow water depth (0.6 m) throughout the creek thereby requiring non-standard sediment traps designed for this study. Suspended sediment collected in traps in 2014 showed residual contamination at the remediated site (∑17PCDD\Fs: 380 pg/g dw;TEQ (TEF fish) < 0.6 pg/g), with concentrations increasing with distance downstream mirroring surface sediment: mean ∑17PCDD\Fs concentration for suspended sediment at the creek mouth was 2200 pg/g (SD 260 pg/g dw) indicating PCDD/F contributions to the harbour. However, congener patterns in bottom sediment and suspended sediment near the remediated site and extending about 100 m downstream were similar to background upstream patterns consistent with atmospheric deposition as the source rather than the historical source which indicated that floodplain remedial actions were successful.

关键词： Dioxins Furans Sediment Remediation Contamination

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

蓝色的丹麦为什么可以风靡全球？

环球人文地理 2021年第11期 40-47页

作者： yoki黄元琪 brooke Mikkel Heribe Tine Uffelemann razvan silas sladjana 丹麦国家旅游局

环球人文地理41蓝色,是丹麦美食的代表色,因为其生产的蓝罐曲奇风靡全球;蓝色,也源于东方的灵感,为丹麦瓷器赢得了"丹麦蓝"的美誉;蓝色,还是大海的延伸,谁能想到,丹麦人将国家水族馆建成了一颗蓝色星球?丹麦有一句名言:"蓝色的天空,绝... 详细信息

环球人文地理41蓝色,是丹麦美食的代表色,因为其生产的蓝罐曲奇风靡全球;蓝色,也源于东方的灵感,为丹麦瓷器赢得了"丹麦蓝"的美誉;蓝色,还是大海的延伸,谁能想到,丹麦人将国家水族馆建成了一颗蓝色星球?丹麦有一句名言:"蓝色的天空,绝不会因为盲人看不见而不存在。"擅长航海的丹麦人,把对蓝色的钟爱刻在了基因中。数个世纪前,维京人用力量和勇气征服大海,现代的丹麦人,则用才华将蓝色的工艺与科技带给全世界。甚至于,连"蓝牙技术"这个名词,都是来源于丹麦国王——哈拉尔嘴里的一颗蓝色牙齿。

关键词：水族馆青花瓷克林格维也纳海洋生物曲奇饼干

Preconditions for Sustainable Development of Bojana River Mouth Surroundings

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Business Review 2022年第4期21卷 124-131页

作者： sladjana Zivanovic Sanja Smolović “Adriatic”University Bar BarMontenegro

By his activity,man leads to degradation of the *** accordance to laws of nature,man has the possibility to adjust nature to his needs only to a certain *** are talking about the limit when man’s behaviour may become devastating when it comes to overall development of living organisms as well as their *** aim of this paper is to show that improvement of the environment by appropriate valorisation of the region of the mouth of Bojana river is a precondition for sustainable development of this region which is very interesting both from the economical as well as ecological point of view considering the rich biodiversity and possibilities for tourist development of the *** term development is usually used to denote growth or ***,this term,especially during the past two centuries,has become a synonym for economical growth considering gross domestic income or income per *** definition has caused a race among nations in order to achieve and maintain development *** goals are often controversial when it comes to the idea of environment *** order to restore a balanced relationship between man and nature,the term sustainable development has been *** this paper,the term sustainable development is understood as development which only enables satisfaction of contemporary needs without endangering the needs of future generations and distracting systems which support life or reduce biodiversity.

关键词： sustainable development sustainability biodiversity tourism

The Ability of Conceptual Monitoring and the Quality of Working Memory at Children With Calculation Difficulties

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Psychology Research 2011年第1期1卷 12-17页

作者： sladjana Arsic Fadilj Eminovic Ivona Stankovic High Medical School of Vocational Training Cuprija Serbia Faculty of Special Education andRehabilitation Belgrade Serbia Head of Clinic for PhysicalMedicine and Rehabilitation Nis Serbia

Calculia is considered to be the ability of performing arithmetic operations, the preconditions for the development of mathematical skills in the complex functioning of psychological functions represented in neuro-anatomical systems, as well in the interaction with the environment. Problems in acquiring arithmetic skills can be described as difficulties in counting as well as developmental dyscalculia. Reported prevalence rate for this problem in general population is 6%-10%. The most common difficulties in counting are: difficulties in logic, difficulties in planning, perseverance of inappropriate (responses) procedures and poor understanding of arithmetic operations. This paper aims to identify the influence of assessed arithmetic skills and to clarify to what extent the assessed cognitive skills affect each other in children with difficulties in counting. The relations between the level of working memory and acquiring of arithmetic skills, between the attention and the conceptual observation, and also between planning ability and acquiring of arithmetic skills have been assessed within the study goals. The tested sample consists of 84 third-grade pupils of general population divided into an experimental and a control group. The subjects of the experimental group were chosen according to the discrepancy between general intellectual competences, general achievement at school and success in the filed of mathematics expressed by school marks. Following tests of neuropsychological test battery were used: (1) Taylor"s word list-Rey test; and (2) Trail-making-TMTa/b test. The results have been analyzed regarding qualitative test results, as well as the aspect of previous knowledge in the studies dealing with dyscalculia. The results of the studies indicate that there is statistically a significant difference in effectiveness of assessed cognitive characteristics of working memory, attention and planning abilities between experimental and control group (sample) (p < 0.01

关键词：计算能力记忆能力儿童影响评估测试样本质量监测算术运算

中东欧国家广播业转型的范例:塞尔维亚广播现状与问题分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国广播 2013年第8期 30-34页

作者：斯拉贾娜·瓦西列维奇(sladjana Vasiljevic)【塞尔维亚】董明锐孟伟塞尔维亚Duboko公共事业委员会不详

起步较早的塞尔维亚的广播业目前已经实现了部分私有化,建立了包括公共广播与商业广播的双轨制,广播在国内受到听众的欢迎,呈现出蓬勃发展的态势,但同时也存在媒体所有权不透明、"海盗电台"盛行等问题。本文对中东欧国家广播事业的整体... 详细信息

起步较早的塞尔维亚的广播业目前已经实现了部分私有化,建立了包括公共广播与商业广播的双轨制,广播在国内受到听众的欢迎,呈现出蓬勃发展的态势,但同时也存在媒体所有权不透明、"海盗电台"盛行等问题。本文对中东欧国家广播事业的整体现状进行了分析,并以塞尔维亚广播业为例做具体的个案研究,具体阐述以上内容。

关键词：中东欧广播事业塞尔维亚