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Genes & Diseases 2024年第5期11卷 66-69页

作者： siyi Liu Juanchan Huang Wei zhao Department of Radiation Oncology Guangxi Medical University Cancer HospitalNanningGuangxi 530000China Guangxi Medical University NanningGuangxi 530000China Department of Oncology Affiliated Wuming Hospital of Guangxi Medical UniversityNanningGuangxi 530000China

Cuproptosis is a newly discovered type of programmed cell death that involves the depletion of intracellular copper and is not influenced by other inhibitors of programmed cell *** modality was first identified and named by Tsvetkov et al in the previous year.1 To further explore the relationship between cuproptosis,the tumor microenvironment,immunotherapy,and prognosis for breast cancer(BC),the expression patterns of 19 cuproptosis-related long non-coding RNAs(lncRNAs)were determined using data from the Cancer Genome Atlas(TCGA).

关键词： breast cancer microenvironment

Fiducial Approach for the Storage Reliability Assessment of Complex Repairable Systems

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Journal of Systems Science & Complexity 2024年第4期37卷 1653-1671页

作者： YANG Yang zhao Letian CHEN siyi YU Dan University of Chinese Academy of Sciences Beijing 100190China Computer Application Institute of Nuclear Industry Beijing 100142China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China

In recent years,there has been a growing focus on high-reliability products in industrial and military *** plays a crucial role in these products,and as a result,research on storage reliability has gained more *** paper specifically targets a class of products with complex structures that require long-term storage,regular testing,and ***,an expression method for system availability is provided based on the reliability structure of the system and the maintenance situation of the constituent equipment in *** the expression of system availability is typically complex and difficult to compute,and the storage life of the system cannot be represented as an explicit function of the reliability indicators of the constituent equipment,it is challenging to evaluate the availability and storage life of repairable *** address this,the paper proposes a comprehensive evaluation methodology for assessing the storage reliability of complex repairable systems based on fiducial *** approach is employed to derive point estimates and determine the lower fiducial limits for both system availability and storage ***,simulation results demonstrate that this comprehensive evaluation method for storage reliability of complex repairable systems is not only convenient but also highly effective.

关键词： Availability fiducial method repairable system storage life

Enhancing AI System Privacy:An Automatic Tool for Achieving GDPR Compliance in NoSQL Databases

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Computers, Materials & Continua 2024年第7期80卷 217-234页

作者： Yifei zhao zhaohui Li siyi Lv College of Cyber Science Nankai UniversityTianjin300350China

The EU’s Artificial Intelligence Act(AI Act)imposes requirements for the privacy compliance of AI *** systems must comply with privacy laws such as the GDPR when providing *** laws provide users with the right to issue a Data Subject Access Request(DSAR).Responding to such requests requires database administrators to identify information related to an individual ***,manual compliance poses significant challenges and is *** administrators need to write queries through time-consuming *** demand for large amounts of data by AI systems has driven the development of NoSQL *** to the flexible schema of NoSQL databases,identifying personal information becomes even more *** paper develops an automated tool to identify personal information that can help organizations respond to *** tool employs a combination of various technologies,including schema extraction of NoSQL databases and relationship identification from query *** describe the algorithm used by our tool,detailing how it discovers and extracts implicit relationships from NoSQL databases and generates relationship graphs to help developers accurately identify personal *** evaluate our tool on three datasets,covering different database designs,achieving an F1 score of 0.77 to *** results demonstrate that our tool successfully identifies information relevant to the data *** tool reduces manual effort and simplifies GDPR compliance,showing practical application value in enhancing the privacy performance of NOSQL databases and AI systems.

关键词： GDPR compliance NoSQL databases AI system privacy

Development of a single transcript CRISPR/Cas9 toolkit for efficient genome editing in autotetraploid alfalfa

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3D-printed Mg-1Ca/polycaprolactone composite scaffolds with promoted bone regeneration

The Crop Journal 2024年第3期 788页

作者： Haixia zhao siyi zhao Yingping Cao Xiping Jiang Lijuan zhao Zhimeng Li Mengqi Wang Ruijuan Yang Chuanen Zhou zhaoming Wang Feng Yuan Dongmei Ma Hao Lin Wenwen Liu Chunxiang Fu

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Journal of Magnesium and Alloys 2024年第3期12卷 966-979页

作者： Xiao zhao siyi Wang Feilong Wang Yuan Zhu Ranli Gu Fan Yang Yongxiang Xu Dandan Xia Yunsong Liu Department of Prosthodontics Peking University School and Hospital of StomatologyBeijing 100081China National Center of Stomatology National Engineering Laboratory for Digital and Material Technology of StomatologyNational Clinical Research Center for Oral DiseasesBeijing Key Laboratory of Digital StomatologyResearch Center of Engineering and Technology for Computerized Dentistry Ministry of HealthNMPA Key Laboratory for Dental MaterialsBeijing 100081China Department of Dental Materials Peking University School and Hospital of StomatologyBeijing 100081China

In bone tissue engineering,polycaprolactone(PCL)is a promising material with good biocompatibility,but its poor degradation rate,mechanical strength,and osteogenic properties limit its *** this study,we developed an Mg-1Ca/polycaprolactone(Mg-1Ca/PCL)composite scaffolds to overcome these *** used a melt blending method to prepare Mg-1Ca/PCL composites with Mg-1Ca alloy powder mass ratios of 5,10,and 20 wt%.Porous scaffolds with controlled macro-and microstructure were printed using the fused deposition modeling *** explored the mechanical strength,biocompatibility,osteogenesis performance,and molecular mechanism of the Mg-1Ca/PCL *** 5 and 10 wt%Mg-1Ca/PCL composites were found to have good ***,they promoted the mechanical strength,proliferation,adhesion,and osteogenic differentiation of human bone marrow stem cells(hBMSCs)of pure *** vitro degradation experiments revealed that the composite material stably released Mg_(2)+ions for a long period;it formed an apatite layer on the surface of the scaffold that facilitated cell adhesion and *** tomography and histological analysis showed that both 5 and 10 wt%Mg-1Ca/PCL composite scaffolds promoted bone regeneration bone *** results indicated that the Wnt/β-catenin pathway was involved in the osteogenic ***,Mg-1Ca/PCL composite scaffolds are expected to be a promising bone regeneration material for clinical *** of significance:Bone tissue engineering scaffolds have promising applications in the regeneration of critical-sized bone ***,there remain many limitations in the materials and manufacturing methods used to fabricate *** study shows that the developed Ma-1Ca/PCL composites provides scaffolds with suitable degradation rates and enhanced boneformation ***,the fused deposition modeling method allows precise control of the macroscopic morphology and microsc

关键词： 3D printing Bone tissue engineering Magnesium Osteogenic Polycaprolactone Scaffold.

保护城市传统与文化的重要元素——论城市色彩

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南京艺术学院学报（美术与设计） 2008年第1期 159-160页

作者：赵思毅东南大学建筑学院江苏南京210096

国际学术界正以保护城市传统人文环境、传承城市地域文化为契机,对城市色彩展开了全方位研究,并将它纳入为城市设计学的有机组成部分。当前最为紧迫的任务就是要将城市的色彩调研纳入计划,建立各个城市的色彩档案,以便更全面有效地为维... 详细信息

国际学术界正以保护城市传统人文环境、传承城市地域文化为契机,对城市色彩展开了全方位研究,并将它纳入为城市设计学的有机组成部分。当前最为紧迫的任务就是要将城市的色彩调研纳入计划,建立各个城市的色彩档案,以便更全面有效地为维护城市人文传统和地域特色提供依据。

关键词：城市色彩城市传统文化城市地域文化

腰椎立体定位斜扳法与传统腰椎斜扳法对椎间盘及关节突关节软骨影响的有限元分析

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中医正骨 2024年第1期36卷 14-22页

作者：丘明旺孙玫瑶吴耿佳黄帆刘嘉俊卢曼琪刘岘严兆贤赵思怡田强吴山范志勇广州中医药大学第二临床医学院广东广州510405 广州中医药大学针灸康复临床医学院广东广州510405 香港理工大学康复科学系中国香港999077 广东省中医院广东广州510120 深圳市龙岗区第五人民医院广东深圳518111

目的:分析腰椎立体定位斜扳法与传统腰椎斜扳法对椎间盘及关节突关节软骨的影响。方法:选取1例成年男性L_(4-5)椎间盘突出症患者(椎间盘向左后方突出),采用西门子Light Speed 64排螺旋CT进行腰椎和骨盆扫描,层厚0.5 mm。基于CT扫描数据... 详细信息

目的:分析腰椎立体定位斜扳法与传统腰椎斜扳法对椎间盘及关节突关节软骨的影响。方法:选取1例成年男性L_(4-5)椎间盘突出症患者(椎间盘向左后方突出),采用西门子Light Speed 64排螺旋CT进行腰椎和骨盆扫描,层厚0.5 mm。基于CT扫描数据,应用三维有限元建模软件建立腰椎-骨盆三维有限元模型,通过与文献数据比较验证模型有效性后,分析腰椎立体定位斜扳法与传统腰椎斜扳法作用下腰椎-骨盆整体应力、L_(4-5)椎间盘应力和位移、L_(4-5)关节突关节软骨应力和位移、L_(4-5)上下关节突表面中心点相对空间距离。结果:①腰椎-骨盆三维有限元模型建立及验证结果。建立的腰椎-骨盆三维有限元模型共有550215个节点、344359个单元,高度模拟了腰椎-骨盆的结构与材料特性。在模拟加载条件下,L_(4-5)节段屈伸、侧屈、轴向旋转活动范围与文献中的既往研究结果基本相同。②模型整体应力。实施传统腰椎斜扳法时,腰椎-骨盆三维有限元模型最大应力为5.31 MPa,主要集中于L_(1)、L_(2)、L_(4)、L_(5)椎体;实施腰椎立体定位斜扳法时,腰椎-骨盆三维有限元模型最大应力为29.30 MPa,主要集中于L_(1)、L_(2)椎体及L_(3)、L_(4)、L_(5)椎弓根。③L_(4-5)椎间盘应力及位移。实施传统腰椎斜扳法时,L_(4-5)椎间盘纤维环平均等效应力为1.12 MPa,纤维环整体向左、向前、向下发生位移,平均位移分别为0.36 mm、0.20 mm、0.05 mm;髓核平均等效应力为0.02 MPa,髓核整体向左、向前、向下发生位移,平均位移分别为0.35 mm、0.24 mm、0.06 mm。实施腰椎立体定位斜扳法时,L_(4-5)椎间盘纤维环平均等效应力为1.14 MPa,纤维环整体向左、向前、向下发生位移,平均位移分别为0.39 mm、1.30 mm、0.05 mm;髓核平均等效应力为0.02 MPa,髓核整体向左、向前、向下发生位移,平均位移分别为0.38 mm、1.30 mm、0.07 mm。④L_(4-5)关节突关节软骨应力及位移。实施传统腰椎斜扳法时,L_(4-5)左侧和右侧关节突关节软骨平均等效应力分别为2.46 MPa、3.18 MPa,平均位移分别为1.10 mm、0.21 mm;实施腰椎立体定位斜扳法时,L_(4-5)左侧和右侧关节突关节软骨平均等效应力分别为2.70 MPa、3.22 MPa,平均位移分别为1.46 mm、0.65 mm。⑤L_(4-5)上下关节突表面中心点相对空间距离。实施传统腰椎斜扳法时,L_(4-5)左、右侧上下关节突表面中心点相对空间距离分别为0.75 mm、0.34 mm;实施腰椎立体定位斜扳法时,L_(4-5)左、右侧上下关节突表面中心点相对空间距离分别为0.81 mm、0.23 mm。结论:腰椎立体定位斜扳法与传统腰椎斜扳法均能使腰椎间盘突出症患者病变节段椎间盘及关节突关节软骨产生一定的应力和位移;相较于传统腰椎斜扳法,腰椎立体定位斜扳法能使病变节段椎间盘和关节突关节软骨产生更大的应力和位移,这也可能是腰椎立体定位斜扳法比传统腰椎斜扳法治疗腰椎间盘突出症疗效更佳的原因。

关键词：推拿疗法有限元分析椎间盘移位腰椎生物力学

Establishment and Application of a Radiation Dose Rate Model for Nuclear Medicine Examinees

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China CDC weekly 2024年第23期6卷 553-557,I0019-I0025页

作者： Yuehua Hu Xinyu He Wenjia zhao Lixin Ding Meiying You Zihan Li Xinyu Liu Miaomiao Wang siyi Chen Ziwei Lu Lei Qu Kuke Ding Li Zhang Qiuxian Fu Office of Epidemiology Chinese Center for Disease Control and PreventionBeijingChina Department of Oncology Central Hospital Affiliated to Shandong First Medical UniversityJinan CityShandong ProvinceChina National Institute for Radiological Protection Chinese Center for Disease Control and PreventionBeijingChina National Center for Chronic and Noncommunicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina Laboratory Animal Center Chinese Center for Disease Control and PreventionBeijingChina National Institute of Parasitic Diseases Chinese Center for Disease Control and PreventionShanghaiChina Office of Public Health Management Chinese Center for Disease Control and PreventionBeijingChina Hainan Medical University Haikou CityHainan ProvinceChina

Introduction:Traditional methods for determining radiation dose in nuclear medicine include the Monte Carlo method,the discrete ordinate method,and the point kernel integration *** study presents a new mathematical model for predicting the radiation dose rate in the vicinity of nuclear medicine ***:A new algorithm was created by combining the physical model of“cylinder superposition”of the human body with integral analysis to assess the radiation dose rate in the vicinity of nuclear medicine ***:The model accurately predicted radiation dose rates within distances of 0.1–3.0 m,with a deviation of less than 11%compared to observed *** model demonstrated greater accuracy at shorter distances from the radiation source,with a deviation of only 1.55%from observed values at 0.1 ***:The model proposed in this study effectively represents the spatial and temporal distribution of the radiation field around nuclear medicine patients and demonstrates good agreement with actual *** model has the potential to serve as a radiation dose rate alert system in hospital environments.

关键词： method. deviation cylinder

情绪效价-空间动作隐喻联结对成人和儿童外语情绪词学习的影响

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心理与行为研究 2022年第2期20卷 153-159页

作者：赵思怡李莹王悦郑州大学教育学院郑州450001 美国康奈尔大学人类发展学系伊萨卡14853

为探究情绪效价与空间动作的隐喻联结如何影响中国成人及学龄前和学龄初期儿童对外语情绪词的学习,要求被试在学习阶段根据情绪效价将新学习的实体外语词卡放在对应空间位置。测试阶段采用二选一迫选任务,记录新词学习的反应时和正确率... 详细信息

为探究情绪效价与空间动作的隐喻联结如何影响中国成人及学龄前和学龄初期儿童对外语情绪词的学习,要求被试在学习阶段根据情绪效价将新学习的实体外语词卡放在对应空间位置。测试阶段采用二选一迫选任务,记录新词学习的反应时和正确率。结果显示,无论是成人组还是儿童组被试,隐喻一致组在测试阶段中对所学外语词的再认反应时均快于隐喻不一致组和控制组。研究表明,成人和学龄前和学龄初期儿童均存在情绪效价–空间动作隐喻联结的心理表征,并且该联结可以影响成人及学龄前和学龄初期儿童外语情绪词学习效果。

关键词：空间隐喻身体动作情绪效价外语情绪词儿童

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基于节点可靠度的虚拟SDN映射算法

计算机应用研究 2017年第7期34卷 2134-2139页

作者：赵思逸陈靖龚水清空军工程大学信息与导航学院西安710077

为应对网络故障,提升网络的可靠性,针对SDN环境设计了节点的可靠度指标,提出了基于节点可靠度的虚拟SDN映射算法。在初始可靠映射阶段,该算法根据节点可靠度指标进行v SDN映射,部署控制器时兼顾了控制器与交换机的时延,同时考虑控制网... 详细信息

为应对网络故障,提升网络的可靠性,针对SDN环境设计了节点的可靠度指标,提出了基于节点可靠度的虚拟SDN映射算法。在初始可靠映射阶段,该算法根据节点可靠度指标进行v SDN映射,部署控制器时兼顾了控制器与交换机的时延,同时考虑控制网络的重要性,为控制网络构建相应的备份资源;在故障恢复阶段,针对物理SDN单节点或单链路故障,算法使用迁移方法应对控制节点失效的情况,使用重映射方法应对其他故障。仿真结果表明,算法在请求接受率、故障恢复率、有效承载率和平均控制时延等指标上取得了较好的结果。

关键词：软件定义网络网络虚拟化虚拟网络映射控制器部署节点可靠度