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Validity and reliability of Sarcopenia Quality of Life® Indonesia questionnaire in sarcopenic patients

Rheumatology & Autoimmunity 2024年第1期4卷 47-56页

作者： Anna Ariane Purwita W.Laksmi siti setiati Rudy Hidayat Suryo Anggoro Kusumo-Wibowo Sumariyono Fadhli Mahri Caroline Tanadi Charlotte Beaudart Internal Medicine Department Rheumatology DivisionFaculty of Medicine Universitas IndonesiaDr.Cipto Mangunkusumo HospitalJakartaIndonesia Internal Medicine Department Geriatric DivisionFaculty of Medicine Universitas IndonesiaDr.Cipto Mangunkusumo HospitalJakartaIndonesia Faculty of Medicine Universitas Indonesia JakartaIndonesia St.Carolus Hospital JakartaIndonesia Department of Biomedical Sciences Namur Research Institute for Life Sciences(NARILIS)Faculty of MedicineUniversity of NamurNamurBelgium

Background:Sarcopenia significantly impairs quality of life(QoL).The Sarcopenia Quality of Life®(SarQol®)questionnaire provides a sarcopenia-specific instrument for the assessment of *** aim of this study was to cross-culturally adapt the SarQol®to an Indonesian language questionnaire and to confirm its validity and reliability as a tool to measure QoL in Indonesian-speaking elderly patients with ***:This cross-sectional study translated and cross-culturally adapted the SarQol®questionnaire,followed by evaluating the psychometric properties of the final cross-culturally adapted SarQol®Indonesia ***:Fifty-nine elderly Indonesian subjects(29 sarcopenic and 30 nonsarcopenic)with a mean age of 72.2±6.3 years were included in this ***®Indonesia questionnaire overall provides a good discriminative value[60.61±14.34 vs.73.60±13.17,p=0.001],good internal consistency(Cronbach'sαcoefficient=0.896 and McDonald'sωcoefficient=0.906,both with good correlation to the questionnaire individual domains),acceptable construct validity,and good test-retest reliability(intraclass correlation coefficient:0.962[95%confidence interval:0.883-0.987]).Conclusions:The SarQol®Indonesia questionnaire provides a conceptual and literally equivalent questionnaire content to its original source with good discriminative value,good internal consistency,acceptable construct validity,and good test-retest *** SarQol®Indonesia questionnaire is ready to be used to measure QoL in Indonesian elderly sarcopenic individuals.

关键词： cross-cultural adaptation quality of life Sarcopenia SarQol validation

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Redefining biofuels:Investigating oil palm biomass as a promising cellulose feedstock for nitrocellulose-based propellant production

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Defence Technology（防务技术） 2024年第7期37卷 111-132页

作者： Khoirul Solehah binti Abdul Rahim Alinda binti Samsuri siti Hasnawati binti Jamal siti Aminah binti Mohd Nor siti Nor Ain binti Rusly Hafizah binti Ariff Nur Shazwani binti Abdul Latif Centre for Tropicalization(CENTROP) Defence Research InstituteUniversiti Pertahanan Nasional MalaysiaKem Sungai Besi57000 Kuala LumpurMalaysia Department of Chemistry and Biology Centre for Defence Foundation StudiesUniversiti Pertahanan Nasional MalaysiaKem Sungai Besi57000 Kuala LumpurMalaysia

This review paper explores the potential of oil palm biomass as a valuable cellulose source for the production of nitrocellulose-based propellants,contributing to the green revolution and sustainable energy *** highlights the availability of the corresponding biomass in Malaysia and in line with global studies,the chemical compositions,as well as a brief description of current technologies for converting biomass of oil palm into value added products specifically *** to achieve maximum utilization of biomass from oil palm industry for cellulose production and prospective source for nitrocellulose-based propellant are also *** methodology section outlines the pretreatment of lignocellulosic fibres,cellulose extraction,and nitrocellulose production ***,the review underscores the prospective of palm oil biomass as a sustainable cellulose source for propellant manufacturing,while acknowledging the need for further research and advancements in the field.

关键词： Biopolymer Cellulose nitrate Energetic materials Green technology Palm oil

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Radiative Blood-Based Hybrid Copper-Graphene Nanoliquid Flows along a Source-Heated Leaning Cylinder

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Computer Modeling in Engineering & Sciences 2024年第4期139卷 1017-1037页

作者： siti Nur Ainsyah Ghani Noor Fadiya Mohd Noor Institute of Mathematical Sciences Faculty of ScienceUniversiti MalayaKuala Lumpur50603Malaysia Center for Data Analytics Consultancy&Services(UM-CDACS) Faculty of ScienceUniversiti MalayaKuala Lumpur50603Malaysia

Variant graphene,graphene oxides(GO),and graphene nanoplatelets(GNP)dispersed in blood-based copper(Cu)nanoliquids over a leaning permeable cylinder are the focus of this *** forms of graphene are highly beneficial in the biological and medical fields for cancer therapy,anti-infection measures,and drug *** non-Newtonian Sutterby(blood-based)hybrid nanoliquid flows are generalized within the context of the Tiwari-Das model to simulate the effects of radiation and heating *** governing partial differential equations are reformulated into a nonlinear set of ordinary differential equations using similar transformational *** equations are then transformed into boundary value problems through a shooting technique,followed by the implementation of the bvp4c tool in *** influences of various parameters on the model’s nondimensional velocity and temperature profiles,reduced skin friction,and reduced Nusselt number are presented for detailed *** results indicated that Cu-GNP/blood and Cu-GO/blood hybrid nanofluids exhibit the lowest and highest velocity distributions,respectively,for increased nanoparticles volume fraction,curvature parameter,Sutterby fluid parameter,Hartmann number,and wall permeability ***,opposite trends are observed for the temperature distribution for all considered parameters,except the mixed convection *** in the reduced skin friction magnitude and the reduced Nusselt number with higher values of graphene/GO/GNP nanoparticle volume fraction are also ***,GNP is identified as the superior heat conductor,with an average increase of approximately 5%and a peak of 7.8%in the reduced Nusselt number compared to graphene and GO nanoparticles in the Cu/blood nanofluids.

关键词： Hybrid nanofluid sutterby fluid tiwari-das model thermal radiation graphene graphene oxides graphene nanoplatelets

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Appraisal of pollution levels and non-carcinogenic health risks associated with the emergence of heavy metals in Indonesian community water for sanitation,hygiene,and consumption

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Emerging Contaminants 2024年第3期10卷 230-249页

作者： Nurul Fahimah Indah Rachmatiah siti Salami Katharina Oginawati Haryo Mubiarto Department of Environmental Engineering Faculty of Civil and Environmental EngineeringInstitut Teknologi BandungJl.Ganesha 10Bandung40132West JavaIndonesia Environmental Management Technology Research Group Department of Environmental EngineeringFaculty of Civil and Environmental EngineeringInstitut Teknologi BandungJl.Ganesha 10Bandung40132West JavaIndonesia Industrial Hygiene and Toxicology Laboratory Faculty of Civil and Environmental EngineeringInstitut Teknologi BandungJl.Ganesha 10Bandung40132West JavaIndonesia

Excessive heavy metal concentrations in water can pose a threat to human *** research analyzed 160 groundwater samples used for hygiene and sanitation,of which 62 were used for consumption,and 98 other types of drinking water were *** research findings indicate that 6%of groundwater for hygiene and sanitation and 13%of drinking water(7.8%groundwater,5.2%refill water)were deemed unfit for use due to elevated concentrations of certain heavy metals surpassing the maximum ***,Cd,Co,Hg,Mn,and Pb were detected in several drinking water samples deemed unsuitable for *** heavy metals suspected to originate from natural sources are Co,Fe,Mn,As,and Zn,while Pb,Cd,Hg,and Co are suspected to have anthropogenic *** arsenic exposure through the ingestion pathway posed a non-carcinogenic health risk to the local *** were found to be more susceptible than adult males and *** estimated average non-carcinogenic risk levels based on the water sources were refill water>well water>rainwater>spring ***,it is essential to monitor raw water sources at refill water depots in the study area and implement policies related to the quality of raw water sources,technology maintenance processes,and the quality of processed water from refill water ***,the community should be educated about householdscale water treatment to minimize health risks and consider using untreated well water and rainwater for consumption.

关键词： Bandung regency Groundwater Heavy metal Human health risk Water quality Refill water

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Single-cell RNA sequencing analysis of the retina under acute high intraocular pressure

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Neural Regeneration Research 2024年第11期19卷 2522-2531页

作者： Shaojun Wang siti Tong Xin Jin Na Li Pingxiu Dang Yang Sui Ying Liu Dajiang Wang Division of Ophthalmology The Third Medical Center of PLA General HospitalBeijingChina Department of Ophthalmology Beijing Rehabilitation HospitalCapital Medical UniversityBeijingChina

High intraocular pressure causes retinal ganglion cell injury in primary and secondary glaucoma diseases,yet the molecular landscape characteristics of retinal cells under high intraocular pressure remain *** models of acute hypertension ocular pressure were established by injection of cross-linked hyaluronic acid hydrogel(Healaflow■).Single-cell RNA sequencing was then used to describe the cellular composition and molecular profile of the retina following high intraocular *** results identified a total of 12 cell types,namely retinal pigment epithelial cells,rod-photoreceptor cells,bipolar cells,Müller cells,microglia,cone-photoreceptor cells,retinal ganglion cells,endothelial cells,retinal progenitor cells,oligodendrocytes,pericytes,and *** single-cell RNA sequencing analysis of the retina under acute high intraocular pressure revealed obvious changes in the proportions of various retinal cells,with ganglion cells decreased by 23%.Hematoxylin and eosin staining and TUNEL staining confirmed the damage to retinal ganglion cells under high intraocular *** extracted data from retinal ganglion cells and analyzed the retinal ganglion cell cluster with the most distinct *** found upregulation of the B3gat2 gene,which is associated with neuronal migration and adhesion,and downregulation of the Tsc22d gene,which participates in inhibition of *** study is the first to reveal molecular changes and intercellular interactions in the retina under high intraocular *** data contribute to understanding of the molecular mechanism of retinal injury induced by high intraocular pressure and will benefit the development of novel therapies.

关键词： apoptosis axon degeneration high intraocular pressure microglia ocular hypertension photoreceptor cells retina retinal degeneration retinal ganglion cells single-cell RNA sequencing

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Structural engineering of antimicrobials for optimal broad-spectrum activity

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Green Chemical Engineering 2024年第4期5卷 473-482页

作者： Arunmozhiarasi Armugam Diane S.W.Lim siti Nurhanna Riduan Shook Pui Chan Jerome Asugan Yugen Zhang Institute of Bioengineering and Bioimaging Institute of Sustainability for Chemicals Energy and Environment(ISCE2) Agency for Science Technology and Research (A*STAR) Diploma in Biomedical Science School of Chemical and Life SciencesSingapore Polytechnic

Antimicrobial materials are a crucial component in eradicating and managing the spread of infectious *** are expected to act on a broad-spectrum of microbes, including emerging pathogens which could cause the next Disease X. Herein, we reassessed a series of antimicrobial imidazolium polymers on our shelves and uncovered extended functionality through dual modes of action. By redesigning their structures, a truly broadspectrum antimicrobial material with optimized activity against bacteria(G +ve, G-ve) and fungi, as well as enveloped and non-enveloped viruses was developed. We demonstrated that the imidazolium polymer exhibits dual modes of function against microbes: targeting the microbial membrane and binding DNA. The latter DNA binding affinity was found to be key against non-enveloped viruses. With this insight, we designed small molecule compounds that exhibited optimum broad-spectrum antimicrobial activity and excellent efficacy against ESKAPE group of pathogens that are responsible for some of the deadliest nosocomial infections worldwide. Our results could also shed light on the design of broad-spectrum antimicrobial compounds against Disease X.

关键词： Broad-spectrum Antimicrobial Polyimidazolium Structure-function Membrane active

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Novel energy recovery from an integrated municipal solid waste and leachate treatment system

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Waste Disposal and Sustainable Energy 2024年第1期6卷 53-61页

作者： siti Salwa Khamis Hadi Purwanto Hamzah Mohd Salleh Alya Naili Rozhan Mohamed Abdur Rahman Mahammadsalman Warimani Noor Alam Faculty of Engineering International Islamic University MalaysiaJalan Gombak53100Kuala LumpurMalaysia Department of Engineering Management Universitas Internasional Semen IndonesiaGresikIndonesia Halalan Thayyiban Research Centre Sultan Sharif Ali Islamic UniversityBandar Seri BegawanBrunei Department of Mechanical Engineering P.A.College of EngineeringMangaloreKarnataka574153India Department of Mechanical Engineering Malaysia-Japan International Institute of TechnologyUniversity of Technology Malaysia54100Kuala LumpurMalaysia

Population growth,waste generation,and massive waste mismanagement have led to environmental *** of municipal solid waste(MSW)requires an efficient and sustainable integrated *** integrated thermal processing of MSW is one of the best waste management *** this study,energy analysis of MSW is carried out based on the material and energy balance of 2000 kg wet MSW,which contains 50%*** the leachate is removed,the dry MSW is sent for carbon content enhancement in carbonization to produce MSW-based ***,the combustion of MSW-based char provided high heat and syngas to be used in a hydrothermal process for MSW leachate *** result shows that the char fuel of MSW produces a sufficient amount of energy,13501.29 MJ(84.55%),in the form of synthetic gas by-product,which has a big potential as an energy *** novelty of the proposed integrated thermal system is to produce 84.55%synthetic gas by-product,which is used for electricity production,cooking,food,and heat energy for industrial *** proposed applications of this paper offer insightful information for policymaking regarding novel MSW techniques,which are economical,energy-efficient,and environmentally ***,it increases the effectiveness of MSW utilization.

关键词： Energy Carbonization Hydrothermal Municipal solid waste Integrated system

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Unusual Presentation of Heart Failure Secondary to Ruptured Aneurysmal Sinus of Valsalva: A Case Report

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World Journal of Cardiovascular Surgery 2024年第1期14卷 1-6页

作者： siti Zubaidah Mohd Zahari Rozaini Hassan National Heart Institute Kuala Lumpur Malaysia

Sinus of Valsalva Aneurysm (SOVA) arises from an abnormal dilation of the aortic root, leading to enlargement between the aortic annulus and the sinotubular junction. Although often presenting without symptoms, these aneurysms bear the potential for life-threatening complications, primarily from the looming risk of rupture. We present the case of a 42-year-old Malay gentleman with a history of bilateral pedal edema and dyspnea on exertion who was diagnosed with a ruptured sinus of Valsalva aneurysm. The patient underwent successful surgical repair of the aneurysm, leading to symptomatic improvement and favorable outcomes. This case highlights the importance of early diagnosis and prompt surgical intervention in managing this uncommon condition.

关键词： Heart Failure Echocardiogram Sinus of Valsalva Aneurysm

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Occurrence of K1 and K2 serotypes and genotypic characteristics of extended spectrumβ-lactamases-producing Klebsiella pneumoniae isolated from selected hospitals in Malaysia

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Asian Pacific Journal of Tropical Medicine 2024年第1期17卷 30-38页

作者： Nurul Syazrah Anuar Hazmin Hazman Sharven Raj Jeyakumar Mohd Nasir Mohd Desa Hasni Idayu Saidi siti Norbaya Masri Nur Afiza Aziz Nurshahira Sulaiman Department of Biomedical Science Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400UPM SerdangSelangorMalaysia Department of Medical Microbiology Faculty of Medicine and Health SciencesUniversiti Putra Malaysia43400UPM SerdangSelangorMalaysia Microbiology Unit Department of PathologyHospital Sultanah AminahJalan Persiaran Sultan Abu Bakar80100 Johor BahruJohorMalaysia

Objective:To determine the distribution,phenotypic and genetic background of extended spectrumβ-lactamases(ESBL)-producing Klebsiella(K.)pneumoniae clinical isolates associated with K1 and K2 serotypes in two selected hospitals in ***:A total of 192 *** isolates were collected and subjected to antibiotic susceptibility,hypermucoviscosity test and multiplex PCR to detect the presence of K1-and K2-serotype associated *** sequence typing(MLST)was performed on ESBL-producing *** isolates presented with K1 and K2 serotypes,followed by phylogenetic ***:A total of 87 out of 192(45.3%)of the *** isolates collected were ESBL ***,only 8.3%(16/192)and 10.9%(21/192)of the total isolates were detected to carry K1-and K2-serotype associated genes,*** analysis showed that K1 and K2 capsular serotypes were not significantly associated with ESBL phenotype(P=0.196).However,they were significantly associated with hypervirulent,as demonstrated by the positive string test(P<0.001).MLST analysis revealed that ST23 as the predominant sequence type(ST)in the K1 serotype,while the ST in the K2 serotype is more ***:Although the occurrence of ESBL-producing isolates among the hypervirulent strains was low,their coexistence warrants the need for continuous *** showed that these isolates were genetically heterogeneous.

关键词： Extended spectrumβ-lactamases Klebsiella pneumoniae Capsular serotypes Genotypic

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Machine Learning-Assisted Fabrication of PCBM-Perovskite Solar Cells with Nanopatterned TiO2 Layer

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Energy & Environmental Materials 2024年第4期7卷 223-230页

作者： siti Norhasanah Sanimu Hwa-Young Yang Jeevan Kandel Ye-Chong Moon Gangasagar Sharma Gaudel Seung-Ju Yu Yong Ju Kim Sejung Kim Bong-Hyun Jun Won-Yeop Rho Graduate School of Integrated Energy-AI Jeonbuk National University School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology (UNIST) Department of Herbal Medicine Resources College of Environmental and Bioresource Sciences Jeonbuk National University School of Chemical Engineering Jeonbuk National University Department of Bioscience and Biotechnology Konkuk University School of International Engineering and Science Jeonbuk National University

To unlock the full potential of PSCs,machine learning （ML） was implemented in this research to predict the optimal combination of mesoporous-titanium dioxide （mp-TiO2） and weight percentage （wt%） of phenyl-C61-butyric acid methyl ester （PCBM）,along with the current density(Jsc),open-circuit voltage (Voc),fill factor （ff）,and energy conversion efficiency （ECE）.

关键词： machine learning nanopatterning PCBM perovskite solar cells prediction

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